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51. 发明申请

US20050214884A1 Method for stabilizing cholesterol dehydrogenase, cholesterol dehydrogenase-containing composition and cholesterol measuring reagent 审中-公开
标题翻译：稳定胆固醇脱氢酶，含胆固醇脱氢酶的组合物和胆固醇测定试剂的方法
公开(公告)号：US20050214884A1
公开(公告)日：2005-09-29
申请号：US10995383
申请日：2004-11-24
申请人： Yasuhiro Sakai , Kenji Isshiki , Kouji Kishi
发明人： Yasuhiro Sakai , Kenji Isshiki , Kouji Kishi
IPC分类号： C12N9/02 , C12N9/04 , C12N9/96 , C12Q1/32 , C12Q1/60 , G01N33/92
CPC分类号： C12N9/96 , C12Q1/60
摘要： The present invention is to provide a novel method for stabilizing cholesterol dehydrogenase. Also, the present invention is to provide a novel cholesterol-containing composition and a cholesterol measuring reagent.
摘要翻译：本发明提供一种稳定胆固醇脱氢酶的新方法。另外，本发明提供一种新型含胆固醇的组合物和胆固醇测定试剂。

52. 发明授权

US06531180B1 Adhesive transparent resin and a composite including the same 失效
标题翻译：粘合剂透明树脂及其组合物
公开(公告)号：US06531180B1
公开(公告)日：2003-03-11
申请号：US09656456
申请日：2000-09-06
申请人： Hidenori Takushima , Yasuhiro Sakai
发明人： Hidenori Takushima , Yasuhiro Sakai
IPC分类号： G02B530
CPC分类号： B32B27/06 , B32B7/12 , B32B2307/416 , B32B2367/00 , B32B2369/00 , B32B2375/00 , B32B2377/00 , C09J7/22 , C09J7/38 , C09J2467/00 , Y10S428/918 , Y10S522/912 , Y10T428/2852 , Y10T428/31551 , Y10T428/31554 , Y10T428/31598 , Y10T428/31609 , Y10T428/31616 , Y10T428/31678
摘要： To provide a transparent resin which is suitable in the process of producing a coating for electronic materials, a glass having both of the scattering-preventing function and the antireflective function, an adhesive agent, a shock-absorbing material, an ultraviolet-cutting sheet for televisions, a filter for VDTs and a high refractive index primer composition as well as the process for the production of primer-coated lenses using said primer composition, is excellent in a coatability, adhesive property, storage stability, durability, shock resistance and the like, and is particularly excellent in a transparency and adhesive property after curing of the same. A transparent resin having an adhesive property characterized by comprising a cured product of the polymerizing composition which comprises at least one of diallyl phthalate, diallyl isophthalate and diallyl terephthalate, and pentaerythritol tetra(3-mercaptopropionate).
摘要翻译：为了提供适合于制造电子材料用涂料的透明树脂，具有防散射功能和抗反射功能两者的玻璃，粘合剂，减震材料，紫外线切割片电视机，用于VDT的过滤器和高折射率底漆组合物以及使用所述底漆组合物生产底漆涂层透镜的方法在涂布性，粘合性，保存稳定性，耐久性，抗冲击性等方面是优异的并且在其固化后的透明性和粘合性特别优异。具有粘合性的透明树脂，其特征在于包含聚合组合物的固化产物，其包含邻苯二甲酸二烯丙酯，间苯二甲酸二烯丙酯和对苯二甲酸二烯丙酯中的至少一种和季戊四醇四（3-巯基丙酸酯）。

53. 发明授权

US06224976B1 Adhesive transparent resin and a composite including the same 失效
标题翻译：粘合剂透明树脂及其组合物
公开(公告)号：US06224976B1
公开(公告)日：2001-05-01
申请号：US08910215
申请日：1997-08-13
申请人： Hidenori Takushima , Riichiro Takeshita , Kouji Futaki , Yasuhiro Sakai
发明人： Hidenori Takushima , Riichiro Takeshita , Kouji Futaki , Yasuhiro Sakai
IPC分类号： B32B712
CPC分类号： B32B27/06 , B32B7/12 , B32B2307/416 , B32B2367/00 , B32B2369/00 , B32B2375/00 , B32B2377/00 , C09J7/22 , C09J7/38 , C09J2467/00 , Y10S428/918 , Y10S522/912 , Y10T428/2852 , Y10T428/31551 , Y10T428/31554 , Y10T428/31598 , Y10T428/31609 , Y10T428/31616 , Y10T428/31678
摘要： To provide a transparent resin which is suitable in the process of producing a coating for electronic materials, a glass having both of the scattering-preventing function and the antireflective function, an adhesive agent, a shock-absorbing material, an ultraviolet-cutting sheet for televisions, a filter for VDTs and a high refractive index primer composition as well as the process for the production of primer-coated lenses using said primer composition, is excellent in a coatability, adhesive property, storage stability, durability, shock resistance and the like, and is particularly excellent in a transparency and adhesive property after curing of the same. A transparent resin having an adhesive property characterized by comprising a cured product of the polymerizing composition which comprises at least one of diallyl phthalate, diallyl isophthalate and diallyl terephthalate, and pentaerythritol tetra(3-mercaptopropionate).
摘要翻译：为了提供适合于制造电子材料用涂料的透明树脂，具有防散射功能和抗反射功能两者的玻璃，粘合剂，减震材料，紫外线切割片电视机，用于VDT的过滤器和高折射率底漆组合物以及使用所述底漆组合物生产底漆涂层透镜的方法在涂布性，粘合性，保存稳定性，耐久性，抗冲击性等方面是优异的并且在其固化之后的透明性和粘合性特别优异.1。一种具有粘合性的透明树脂，其特征在于包含聚合组合物的固化产物，其包括邻苯二甲酸二烯丙酯，间苯二甲酸二烯丙酯和对苯二甲酸二烯丙酯中的至少一种，以及季戊四醇四（3-巯基丙酸酯）。

54. 发明授权

US5985858A Phosphonic diester derivatives 失效
标题翻译：膦酸二酯衍生物
公开(公告)号：US5985858A
公开(公告)日：1999-11-16
申请号：US91946
申请日：1998-06-26
申请人： Kazuyoshi Miyata , Yasuhiro Sakai , Yasuo Shoji , Yoshihiko Tsuda , Yasuhide Inoue , Keigo Sato , Shinya Miki
发明人： Kazuyoshi Miyata , Yasuhiro Sakai , Yasuo Shoji , Yoshihiko Tsuda , Yasuhide Inoue , Keigo Sato , Shinya Miki
IPC分类号： C07F9/6509 , C07F9/6539 , C07F9/6553 , C07F9/6558 , C07F9/6561 , A61K31/67 , A61K31/675
CPC分类号： C07F9/650964 , C07F9/6539 , C07F9/655345 , C07F9/65583 , C07F9/65586 , C07F9/6561
摘要： A phosphonic diester derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents a cycloalkyl group; a phenyl group which may have 1 to 3 substituents selected from the group consisting of a lower alkoxy group, a lower alkyl group, a halogen atom, a halogen-substituted lower alkyl group, a lower alkanoyl group, a nitro group, a benzoyl group, a cyano group, an N-lower alkylcarbamoyl group, an N-phenyl-lower alkylcarbamoyl group, an N-(halogen-substituted phenyl)carbamoyl group and an N,N-di-lower alkylcarbamoyl group; a 1,3,4-thiadiazol-2-yl group having a halogen-substituted lower alkyl group as a substituent; a thiazolyl group; a pyridyl group which may be substituted by a halogen atom; a benzothiazol-2-yl group having 1 to 2 lower alkoxy groups on the phenyl ring; or a 4,5-dihydrothieno[3,2-e]benzothiazol-2-yl group; R.sup.2 represents a hydrogen atom or a phenyl lower alkyl group; R.sup.3 and R.sup.4 each represents a lower alkyl group; and A represents a heterocyclic ring selected from the group consisting of a pyrazine ring, a thiophene ring and a phenyl-substituted thiazole ring; the derivative being of value as an agent for treating and preventing hyperlipidemia, diabetes and cataract, or as an antitumor agent.
摘要翻译： PCT No.PCT / JP96 / 03775第 371日期：1998年6月26日 102（e）日期1998年6月26日PCT 1996年12月24日PCT公布。公开号WO97 / 24360 PCT 日期：1997年7月10日由下式（1）表示的膦酸二酯衍生物：其中R1表示环烷基; 可以具有1〜3个选自低级烷氧基，低级烷基，卤素原子，卤素取代的低级烷基，低级烷酰基，硝基，苯甲酰基的取代基的苯基，氰基，N-低级烷基氨基甲酰基，N-苯基 - 低级烷基氨基甲酰基，N-（卤素取代的苯基）氨基甲酰基和N，N-二低级烷基氨基甲酰基; 具有卤素取代的低级烷基作为取代基的1,3,4-噻二唑-2-基; 噻唑基可被卤素原子取代的吡啶基; 在苯环上具有1至2个低级烷氧基的苯并噻唑-2-基; 或4,5-二氢噻吩并[3,2-e]苯并噻唑-2-基; R2表示氢原子或苯基低级烷基; R3和R4各自表示低级烷基; A表示选自吡嗪环，噻吩环和苯基取代的噻唑环的杂环; 该衍生物作为治疗和预防高脂血症，糖尿病和白内障或作为抗肿瘤剂的药剂是有价值的。

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