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51. 发明申请

US20120016103A1 PEPSTATIN A DERIVATIVES 有权
标题翻译： PEPSTATIN衍生物
公开(公告)号：US20120016103A1
公开(公告)日：2012-01-19
申请号：US12990247
申请日：2009-04-30
申请人： Claudia Borelli , Hans Christian Korting , Elisabeth Ruge , Hans Dieter Hoeltje , Robert Huber , Beate Koksch , Cosimo Damiano Cadicamo
发明人： Claudia Borelli , Hans Christian Korting , Elisabeth Ruge , Hans Dieter Hoeltje , Robert Huber , Beate Koksch , Cosimo Damiano Cadicamo
IPC分类号： C07K7/06 , C07K1/107
CPC分类号： C07K7/02
摘要： The invention relates to a compound having a structure according to the general formula P3-P2-P1-P1′-P2′ (I), wherein residues P3, P2, P1, P1′ and P2′ are specifically defined and may be, e.g., certain amino acid residues. The invention further relates to the use of said compound and to a method for synthesizing a peptide.
摘要翻译：本发明涉及具有根据通式P3-P2-P1-P1'-P2'（I）的结构的化合物，其中残基P3，P2，P1，P1'和P2'是具体限定的，可以是例如，某些氨基酸残基。本发明还涉及所述化合物和合成肽的方法的用途。

52. 发明授权

US08037470B2 Manufacturing system software version management 有权
标题翻译：制造系统软件版本管理
公开(公告)号：US08037470B2
公开(公告)日：2011-10-11
申请号：US11860145
申请日：2007-09-24
申请人： Robert Huber
发明人： Robert Huber
IPC分类号： G06F9/44 , G06F9/445
CPC分类号： G06F8/71
摘要： Version management for manufacturing system software involves a two-part data structure, having two identifiers that are separately and automatically modified, depending upon the changes or modifications that are made, respectively, to top-level and lower-level subsets of manufacturing system programs. According to various other aspects of the present invention, methods for managing revisions involve automatically assigning a version designator under preselected conditions, automatically notifying personnel having a need to know of the change, and managing revisions by way of a revision compare function.
摘要翻译：制造系统软件的版本管理涉及两部分数据结构，具有分别自动修改的两个标识符，这取决于分别对制造系统程序的顶级和低级子集进行的更改或修改。根据本发明的各种其他方面，用于管理修订的方法包括在预选条件下自动分配版本指示符，自动通知需要知道变化的人员，以及通过修订比较功能来管理修订。

53. 发明申请

US20100240076A1 IMMUNOASSAY INVOLVING MUTANT ANTIGENS TO REDUCE UNSPECIFIC BINDING 审中-公开
标题翻译：免疫突变涉及突变型抗体以减少无意义的结合
公开(公告)号：US20100240076A1
公开(公告)日：2010-09-23
申请号：US12376774
申请日：2007-07-12
申请人： Uwe Jacob , Constanze Breithaupt , Robert Huber
发明人： Uwe Jacob , Constanze Breithaupt , Robert Huber
IPC分类号： G01N33/53
CPC分类号： G01N33/6896 , G01N33/6854 , G01N2333/70503 , G01N2800/285
摘要： A method for a quantitative in vitro analysis to diagnose, to categorise, to predict and/or to monitor the progression of a condition comprising the following steps: a) Obtaining a sample suspected of containing anti-A-antibodies from a subject to be analysed, b) Providing native and mutant antigen A, c) Contacting the sample suspected of containing anti-A-antibodies with mutant antigen A and with native antigen A, d) Detecting the amount of anti-A-antibodies bound to native antigen A after step c), wherein the presence of anti-A-antibodies bound to native antigen A allows the diagnosis, the categorisation, the prediction and/or the monitoring of the progression of a condition.
摘要翻译：一种用于诊断，分类，预测和/或监测病症进展的定量体外分析的方法，包括以下步骤：a）从待分析的受试者获得怀疑含有抗A抗体的样品 b）提供天然和突变抗原A，c）将怀疑含抗A抗体的样品与突变抗原A和天然抗原A接触，d）检测与天然抗原A结合的抗A抗体的量步骤c），其中与天然抗原A结合的抗A抗体的存在允许对病症进展的诊断，分类，预测和/或监测。

54. 发明授权

US07784968B2 Slide controller for an audio mixer 有权
标题翻译：用于音频混合器的滑动控制器
公开(公告)号：US07784968B2
公开(公告)日：2010-08-31
申请号：US12048479
申请日：2008-03-14
申请人： Robert Huber
发明人： Robert Huber
IPC分类号： F21V33/00
CPC分类号： H04H60/04 , G06F3/0362 , G11B27/038
摘要： A controller or adjustment device may adjust a value of a parameter for different functions. The adjustment device may include actuators, which may be associated with one or more functions. A light source in proximity to the adjustment device may identify the function of the device. Mixers and filters may automatically modify the hue and/or value of the color based on the selected function. A different color light may be used to identify different functions of the adjustment device.
摘要翻译：控制器或调节装置可以调整不同功能的参数值。调节装置可以包括可以与一个或多个功能相关联的致动器。靠近调节装置的光源可以识别装置的功能。混合器和过滤器可以根据所选择的功能自动修改色彩和/或颜色的值。可以使用不同的颜色的光来识别调节装置的不同功能。

55. 发明授权

US07601512B2 Methods for identifying inhibitors of the 20S and 26S proteasome 失效
标题翻译：鉴定20S和26S蛋白酶体抑制剂的方法
公开(公告)号：US07601512B2
公开(公告)日：2009-10-13
申请号：US10621866
申请日：2003-07-17
申请人： Christian Aichinger , Peter Schreier , Ronald Ebbert , Robert Huber , Michael Groll
发明人： Christian Aichinger , Peter Schreier , Ronald Ebbert , Robert Huber , Michael Groll
IPC分类号： C12Q1/68 , C12Q1/18
CPC分类号： A01N61/00 , C12Q1/18
摘要： The present invention relates to methods for identifying fungicides and also inhibitors of the 20S and 26S proteasomes, to methods for isolating 20S proteasomes, to the use of 20S proteasomes for identifying fungicides and to the use of the inhibitors of 26S and/or 20S proteasomes as fungicides.
摘要翻译：本发明涉及用于鉴定杀真菌剂以及20S和26S蛋白酶体抑制剂的方法，用于分离20S蛋白酶体的方法，使用20S蛋白酶体鉴定杀真菌剂以及使用26S和/或20S蛋白酶体抑制剂作为杀菌剂。

56. 发明申请

US20080202257A1 Coriolis mass flowmeter with an oscillatable straight measuring tube 有权
标题翻译：科里奥利质量流量计，带有可摆动的直管
公开(公告)号：US20080202257A1
公开(公告)日：2008-08-28
申请号：US11984301
申请日：2007-11-15
申请人： Satish Gunturi , Frank Kassubek , Jorg Gebhardt , Lothar Deppe , Matthias Dettmer , Rene Friedrichs , Robert Huber , Steffen Keller
发明人： Satish Gunturi , Frank Kassubek , Jorg Gebhardt , Lothar Deppe , Matthias Dettmer , Rene Friedrichs , Robert Huber , Steffen Keller
IPC分类号： G01F1/84
CPC分类号： G01F1/849 , G01F1/8413 , G01F1/8418
摘要： The disclosure relates to a Coriolis mass flowmeter with an oscillatable straight measuring tube consisting of a corrosion-resistant metal, in particular of titanium or a titanium alloy, to which are attached mounted parts connected directly to the measuring tube for the implementation of the Coriolis measurement principle. Furthermore, stabilizing elements running parallel to the measuring tube are coupled to the measuring tube via mounted parts connected directly to the measuring tube, the mounted parts and the stabilizing elements consisting of a metal other than that of the measuring tube. The stabilizing elements are manufactured from a second material which possesses a coefficient of thermal expansion adapted to the metal of the measuring tube. The mounted parts connected directly to the measuring tube are manufactured from a third material which possesses a higher coefficient of thermal expansion than the metal of the measuring tube.
摘要翻译：本公开涉及一种科里奥利质量流量计，其具有由耐腐蚀金属，特别是钛或钛合金组成的可振荡直测量管，附接的安装部件直接连接到测量管，用于实施科里奥利测量原理。此外，平行于测量管行进的稳定元件通过直接连接到测量管，安装部件和稳定元件的测量管连接到测量管以外的金属。稳定元件由具有适合于测量管的金属的热膨胀系数的第二材料制成。与测量管直接连接的安装部件由具有比测量管的金属更高的热膨胀系数的第三材料制造。

57. 外观设计

USD569370S1 Portion of an audio mixer 有权
公开(公告)号：USD569370S1
公开(公告)日：2008-05-20
申请号：US29255262
申请日：2006-03-06
申请人： Rene Wussler , Andy Brown , Robert Huber
设计人： Rene Wussler , Andy Brown , Robert Huber

58. 发明申请

US20070274062A1 Slide Controller for an Audio-Mixer 有权
标题翻译：用于音频混合器的幻灯片控制器
公开(公告)号：US20070274062A1
公开(公告)日：2007-11-29
申请号：US10568791
申请日：2004-08-11
申请人： Robert Huber
发明人： Robert Huber
IPC分类号： F21V33/00
CPC分类号： H05K5/0017 , H04H60/04
摘要： The invention relates to a slide control for an audio mixer, whereby a slide can be displaced along a defined path in a slit-shaped opening in a front plate. The aim of the invention is to create one such slide control that clearly indicates the function it is carrying out or the parameters it can influence by its position. To this end, an illuminable element is provided, said element extending along the opening.
摘要翻译：本发明涉及一种用于音频混合器的滑动控制装置，由此滑块可沿着前板中的狭缝形开口中的限定路径移位。本发明的目的是创建一个这样的滑动控制，其清楚地指示其正在执行的功能或其可以通过其位置影响的参数。为此，提供可照亮元件，所述元件沿开口延伸。

59. 发明授权

US07074896B1 Recombinant soluble Fc receptors 有权
公开(公告)号：US07074896B1
公开(公告)日：2006-07-11
申请号：US09856933
申请日：1999-12-03
申请人： Peter Sondermann , Robert Huber , Uwe Jacob
发明人： Peter Sondermann , Robert Huber , Uwe Jacob
IPC分类号： C07K14/00 , A61K39/00
CPC分类号： C07K14/70535 , A61K38/00 , C07K2299/00
摘要： Recombinant soluble Fc receptors according to the present invention are characterized by the absence of transmembrane domains, signal peptides and glycosylation. Such Fc receptors can easily be obtained by expressing respective nucleic acids in prokaryotic host cells and renaturation of the obtained inclusion bodies, which procedure leads to a very homogenous and pure product. The products can be used for diagnostic as well as pharmaceutical applications and also for the generation of crystal structure data. Such crystal structure data can be used for the modelling of artificial molecules. A further embodiment comprises coupling the Fc receptors according to the invention to solid materials like chromatography materials that can be used to separate and/or enrich antibodies.

60. 发明申请

US20050260727A1 Crystal structure of the mitochondrial protoporphyrinogen IX oxidase 审中-公开
标题翻译：线粒体原卟啉原IX氧化酶的晶体结构
公开(公告)号：US20050260727A1
公开(公告)日：2005-11-24
申请号：US11078991
申请日：2005-03-11
申请人： Jorg Freigang , Michael Koch , Constanze Breithaupt , Reiner Kiefersauer , Albrecht Messerschmidt , Robert Huber
发明人： Jorg Freigang , Michael Koch , Constanze Breithaupt , Reiner Kiefersauer , Albrecht Messerschmidt , Robert Huber
IPC分类号： C12N9/02 , G01N33/48 , G01N33/50 , G06F19/00
CPC分类号： C12N9/001 , C07K2299/00 , C12Y103/03004
摘要： The present invention relates to crystals of a protoporphyrinogen IX oxidase, to processes for preparing crystals of a protoporphyrinogen IX oxidase, to processes for determining the structure of protoporphyrinogen IX oxidases alone or complexed with a ligand, and to processes for identifying ligands of the mitochondrial protoporphyrinogen IX oxidase, which may be used as herbicides. The present invention also relates to the use of the crystal structure described here of the Nicotiana tabacum mitochondrial protoporphyrinogen IX oxidase for generating protein models of related enzymes and to the identification of inhibitors of related proteins.
摘要翻译：本发明涉及原卟啉原IX氧化酶的晶体，用于制备原卟啉原IX氧化酶的晶体的方法，用于确定单独或与配体络合的原卟啉原IX氧化酶的结构的方法，以及用于鉴定线粒体原卟啉原配体的方法 IX氧化酶，可用作除草剂。本发明还涉及这里描述的烟草线粒体原卟啉原IX氧化酶的晶体结构用于产生相关酶的蛋白质模型和鉴定相关蛋白质的抑制剂。

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