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51. 发明授权

US08921563B2 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof 有权
标题翻译： 1 - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其制备方法和用途
公开(公告)号：US08921563B2
公开(公告)日：2014-12-30
申请号：US13697857
申请日：2011-04-08
申请人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
发明人： Yunfeng Li , Rifang Yang , Youzhi Zhang , Yongzhen Li , Zengliang Jin , Peng Li , Li Yuan , Liuhong Yun , Nan Zhao , Cheng Zhang , Xiaodan Xu , Rusheng Zhao , Hongxia Chen , Rui Xue , Juanjuan Qin , Zhenzhen Wang , Jiazhi Yao
IPC分类号： A61K31/445 , A61K31/505 , C07D211/68 , C07D239/02 , C07D401/06
CPC分类号： C07D401/06
摘要： Provided are N-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives represented by formula I, stereoisomers, pharmaceutically acceptable salts or solvates thereof. The above compounds have the dual activities of 5-hydroxytryptamine 1A receptor ligand and selective serotonin reuptake inhibitor. The preparation methods of the above compounds, the uses of these compounds for the prevention or treatment of nervous system diseases related to 5-hydroxytryptamine system dysfunction and the pharmaceutical compositions containing these compounds are also provided.
摘要翻译：提供由式I表示的N - [（4-羟基哌啶-4-基）甲基]吡啶-2（1H） - 酮衍生物，其立体异构体，药学上可接受的盐或溶剂合物。上述化合物具有5-羟色胺1A受体配体和选择性5-羟色胺再摄取抑制剂的双重活性。还提供了上述化合物的制备方法，这些化合物用于预防或治疗与5-羟色胺系统功能障碍有关的神经系统疾病的用途和含有这些化合物的药物组合物。

52. 发明授权

US08846693B2 Optionally substituted pyrazolo[3,4-d]pyrimidine-4,6-diones 有权
标题翻译：取代的吡唑并[3,4-d]嘧啶-4,6-二酮
公开(公告)号：US08846693B2
公开(公告)日：2014-09-30
申请号：US12746231
申请日：2008-12-06
申请人： Peng Li , Jun Zhao , Hailin Zheng
发明人： Peng Li , Jun Zhao , Hailin Zheng
IPC分类号： C07D487/04 , A61K31/519 , A61P25/24 , A61P25/22 , A61P15/10 , A61P9/12
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06
摘要： 1- or 2- or 7-(substituted)-3-(optionally hetero)arylamino-[1H,2H]-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione derivatives, in free, salt or prodrug form, are useful as pharmaceuticals, particularly as phosphodiesterase 1 inhibitors, useful for the treatment of diseases involving disorders of the dopamine D1 receptor intracellular pathway, such as Parkinson's disease, depression, narcolepsy and damage to cognitive function, e.g., in schizophrenia or disorders that may be ameliorated through enhanced progesterone-signaling pathway, e.g., female sexual dysfunction.
摘要翻译： 1-或2-或7-（取代的）-3-（任选杂）芳基氨基 - [1H，2H] - 吡唑并[3,4-d]嘧啶-4,6（5H，7H） - 二酮衍生物，盐或前药形式，可用作药物，特别是作为磷酸二酯酶抑制剂，可用于治疗涉及多巴胺D1受体细胞内途径疾病的疾病，例如帕金森病，抑郁症，发作性睡病和对认知功能的损害，例如，精神分裂症或通过增强的孕激素信号传导途径可能改善的疾病，例如女性性功能障碍。

53. 发明授权

US08829008B2 Organic compounds 有权
标题翻译：有机化合物
公开(公告)号：US08829008B2
公开(公告)日：2014-09-09
申请号：US13486264
申请日：2012-06-01
申请人： Peng Li
发明人： Peng Li
IPC分类号： A61K31/519
CPC分类号： C07D487/14 , A61K31/519 , A61K45/06
摘要： 1- or 2-substituted (6aR,9aS)-3-(phenylamino)-5-6a,7,8,9,9a-hexahydro-5-methyl-cyclopent[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(1H or, 2H)-one compounds of Formula (I), processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising them.
摘要翻译： 1-或2-取代的（6aR，9aS）-3-（苯基氨基）-5-6a，7,8,9,9a-六氢-5-甲基 - 环戊基[4,5]咪唑并[1,2-a] （I）的吡唑并[4,3-e]嘧啶-4（1H或2H） - 酮化合物，其制备方法，它们作为药物的用途和包含它们的药物组合物。

54. 发明申请

US20140199263A1 HETEROCYCLIC-SUBSTITUTED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 有权
标题翻译：杂环取代的苯唑嘌呤衍生物及其用于治疗病毒性疾病的方法
公开(公告)号：US20140199263A1
公开(公告)日：2014-07-17
申请号：US14343448
申请日：2012-08-16
申请人： Casey Cameron McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Zhong Lai , Qun Dang , Nicolas Zorn
发明人： Casey Cameron McComas , Nigel J. Liverton , Joerg Habermann , Uwe Koch , Frank Narjes , Peng Li , Xuanjia Peng , Richard Soll , Hao Wu , Anandan Palani , Xing Dai , Hong Liu , Shuwen He , Zhong Lai , Qun Dang , Nicolas Zorn
IPC分类号： C07D513/04 , A61K31/497 , C07D405/14 , A61K31/4439 , C07D413/14 , A61K31/4245 , A61K31/444 , A61K31/506 , C07D498/04 , C07D417/14 , A61K31/5377 , A61K31/501 , A61K31/433 , C07D409/14 , A61K31/5365 , A61K31/5383 , C07F7/10 , A61K31/695 , A61K45/06 , C07D471/04
CPC分类号： A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/695 , A61K45/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04 , C07D513/04 , C07F7/10 , Y02A50/385 , Y02A50/387 , Y02A50/389 , A61K31/424 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译：本发明涉及可用作丙型肝炎病毒（HCV）NS5B聚合酶抑制剂，这种化合物的合成以及这些化合物用于抑制HCV NS5B聚合酶活性用于治疗或预防HCV感染的式（I）化合物并用于在基于细胞的系统中抑制HCV病毒复制和/或病毒生产。

55. 发明申请

US20140064117A1 UPLINK SYNCHRONIZATION IN A MULTI-SIM USER EQUIPMENT 有权
标题翻译：多SIM卡用户设备中的上行同步
公开(公告)号：US20140064117A1
公开(公告)日：2014-03-06
申请号：US13777539
申请日：2013-02-26
申请人： Tom Chin , Kuo-Chun Lee , Ian J. Fevrier , Peng Li , Danlu Zhang , Guangming Shi
发明人： Tom Chin , Kuo-Chun Lee , Ian J. Fevrier , Peng Li , Danlu Zhang , Guangming Shi
IPC分类号： H04W56/00
CPC分类号： H04W56/00 , H04W56/0045 , H04W88/06
摘要： A method of wireless communication in a dual subscriber identification module (SIM) terminal includes transmitting a first synchronization message from a first module associated with a first SIM. The method also includes receiving a first acknowledgment (ACK) message on a fast physical access channel (FPACH) in response to the first synchronization message. The method further includes sharing timing information included in the first ACK between the first module and a second module.
摘要翻译：在双用户识别模块（SIM）终端中的无线通信的方法包括从与第一SIM相关联的第一模块发送第一同步消息。该方法还包括响应于第一同步消息在快速物理接入信道（FPACH）上接收第一确认（ACK）消息。该方法还包括在第一模块和第二模块之间共享包括在第一ACK中的定时信息。

56. 发明授权

US08650492B1 System and method for page navigation visualization and analysis 有权
标题翻译：页面导航可视化和分析的系统和方法
公开(公告)号：US08650492B1
公开(公告)日：2014-02-11
申请号：US13271214
申请日：2011-10-11
申请人： Lik Mui , Peng Li , Zhiting Xu , Hao Li , Fenghui Zhang , Lin Liao
发明人： Lik Mui , Peng Li , Zhiting Xu , Hao Li , Fenghui Zhang , Lin Liao
IPC分类号： G06F15/177
CPC分类号： G06F17/30873 , H04L43/045 , H04L43/0829
摘要： Systems and methods for generating a navigation flow visualization of network traffic. The system and method configured to receive user input that identifies a node that is a grouping of network resources. Generating a visualization data of network traffic flowing into the identified node from the incoming nodes and displaying the network traffic flowing out of the identified node to the outgoing nodes. The method includes connecting the incoming nodes with the identified node using the connectors, the connectors having a width dimension that indicates a number of visits from the incoming nodes to the identified node. The method includes connecting the identified node with the outgoing nodes using the connectors that has a width dimension that indicates a number of visits from the identified node to the outgoing nodes.
摘要翻译：用于生成网络流量的导航流可视化的系统和方法。被配置为接收标识作为网络资源分组的节点的用户输入的系统和方法。从入站节点生成流入识别节点的网络流量的可视化数据，并将流出标识节点的网络流量显示给输出节点。该方法包括使用连接器将输入节点与所识别的节点相连，所述连接器具有指示从进入节点到所识别的节点的访问次数的宽度维度。该方法包括使用具有指示从所识别的节点到输出节点的访问次数的宽度维度的连接器来将所识别的节点与输出节点连接。

57. 发明申请

US20140012520A1 PHOTOVOLTAIC STRING MONITOR 审中-公开
标题翻译：光伏监视器
公开(公告)号：US20140012520A1
公开(公告)日：2014-01-09
申请号：US13541105
申请日：2012-07-03
申请人： Ye Zhao , Peng Li , Bradley Lehman , Gianfranco de Palma
发明人： Ye Zhao , Peng Li , Bradley Lehman , Gianfranco de Palma
IPC分类号： G06F19/00 , H02H9/02
CPC分类号： H02H3/042 , H02H3/046 , H02H7/20
摘要： A photovoltaic string monitor that provides PV-string level monitoring to detect abnormal operating conditions. The photovoltaic string monitor includes an indicator unit for indicating normal conditions, existing abnormal conditions or past occurrence of abnormal conditions. In one embodiment, the photovoltaic string monitor includes a plurality of lights and an LCD display.
摘要翻译：一个光伏串监测器，提供PV级串级监控，以检测异常运行状况。光伏串监视器包括用于指示正常状态，现有异常状况或异常情况的过去发生的指示器单元。在一个实施例中，光伏串监视器包括多个灯和LCD显示器。

58. 发明申请

US20140008415A1 WELDING SYSTEM AND METHOD FOR AUTOMATIC WELDING 审中-公开
标题翻译：焊接系统及自动焊接方法
公开(公告)号：US20140008415A1
公开(公告)日：2014-01-09
申请号：US13562787
申请日：2012-07-31
申请人： Hongyuan Shen , Peng Li , Tingting Yang , Yuanbiao Wu , Zhixue Peng , Cheng Sun , Attila Szabo , Meilong Li
发明人： Hongyuan Shen , Peng Li , Tingting Yang , Yuanbiao Wu , Zhixue Peng , Cheng Sun , Attila Szabo , Meilong Li
IPC分类号： B23K3/00
CPC分类号： B23K9/0216 , B23K9/0956 , B23K9/126
摘要： A welding system for automatically welding a welding seam includes a welding arm, a sensor and a controller. The controller includes a welding seam contour detection component, a welding seam contour calculation component, a welding trajectory point calculation component, and a welding parameter setting component. The welding seam contour detection component is used for detecting an initial welding seam contour and detecting remaining welding seam contours after welding each layer of the welding seam. The welding seam contour calculation component is used for calculating the detected welding seam contours. The welding trajectory point calculation component is used for calculating welding trajectory points based on the calculated welding seam contours. The welding parameter setting component is used for setting welding parameters based on the calculated welding seam contours and the calculated welding trajectory points.
摘要翻译：用于自动焊接焊缝的焊接系统包括焊接臂，传感器和控制器。控制器包括焊缝轮廓检测部件，焊缝轮廓计算部件，焊接轨迹点计算部件和焊接参数设定部件。焊缝轮廓检测部件用于检测初始焊缝轮廓，并在焊接每层焊缝之后检测剩余焊缝轮廓。焊缝轮廓计算组件用于计算检测到的焊缝轮廓。焊接轨迹点计算组件用于根据计算的焊缝轮廓计算焊接轨迹点。焊接参数设置组件用于根据计算的焊缝轮廓和计算的焊接轨迹点设置焊接参数。

59. 发明授权

US08615201B1 System for communications link components 有权
标题翻译：通信链路组件系统
公开(公告)号：US08615201B1
公开(公告)日：2013-12-24
申请号：US12250465
申请日：2008-10-13
申请人： Peng Li
发明人： Peng Li
IPC分类号： H04B17/00
CPC分类号： H04B17/3912
摘要： Design systems are provided to assist users in designing circuits that include communications links. A communications link may include a transmitter link subsystem, a receiver link subsystem, and a channel subsystem that interconnects the transmitter and receiver subsystems. A user may specify global link performance characteristics such as bit error rate and data rate. Measured link subsystem performance characteristics may be gathered and stored in a database as probability distribution functions. When analyzing a link, known link subsystems parameters supplied by the user may be used to retrieve appropriate link subsystem performance data. The retrieved link subsystem data and the global link performance data may be analyzed and used to produce recommended subsystem limits. A logic design system may use information on a user's logic design and the recommended limits in producing programmable logic device configuration data.
摘要翻译：提供设计系统以帮助用户设计包括通信链路的电路。通信链路可以包括发射机链路子系统，接收机链路子系统和互连发射机和接收机子系统的信道子系统。用户可以指定全局链路性能特征，例如误码率和数据速率。测量的链路子系统性能特征可以作为概率分布函数收集并存储在数据库中。当分析链路时，可以使用用户提供的已知链路子系统参数来检索适当的链路子系统性能数据。检索的链路子系统数据和全局链路性能数据可以被分析并用于产生推荐的子系统限制。逻辑设计系统可以使用关于用户逻辑设计的信息和用于生成可编程逻辑器件配置数据的推荐限制。

60. 发明申请

US20130331363A1 ORGANIC COMPOUNDS 有权
标题翻译：有机化合物
公开(公告)号：US20130331363A1
公开(公告)日：2013-12-12
申请号：US13701244
申请日：2011-05-31
申请人： Peng Li , Jun Zhao
发明人： Peng Li , Jun Zhao
IPC分类号： A61K31/519 , A61K45/06 , A61K31/5575 , C07D487/14
CPC分类号： A61K31/519 , A61K31/5575 , A61K45/06 , C07D487/14
摘要： Optionally substituted (1- or 3-oxy)-4,5,7,8-tetrahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-imidazo[1,2-a]pyrrolo[3,4-e]pyrimidine or (1- or 3-oxy)-4,5,7,8,9-pentahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-pyrimido[1,2-a]pyrrolo[3,4-e]pyrimidine compounds, processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising the same.
摘要翻译：任选取代的（1-或3-氧）-4,5,7,8-四氢 - （任选4-氧代，4-硫代或4-亚氨基）-2H-咪唑并[1,2-a]吡咯并[ 4-e]嘧啶或（1-或3-氧）-4,5,7,8,9-五氢 - （任选4-氧代，4-硫代或4-亚氨基）-2H-嘧啶并[1,2- a]吡咯并[3,4-e]嘧啶化合物，其制备方法，它们作为药物的用途和包含其的药物组合物。

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