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51. 发明申请

US20100316556A1 MULTISTAGE REACTORS FOR CONTINUOUS PRODUCTION OF CARBON NANOTUBES 有权
标题翻译：连续生产碳纳米管的多级反应器
公开(公告)号：US20100316556A1
公开(公告)日：2010-12-16
申请号：US12516166
申请日：2008-04-18
申请人： Fei Wei , Yi Liu , Weizhong Qian , Guohua Luo
发明人： Fei Wei , Yi Liu , Weizhong Qian , Guohua Luo
IPC分类号： D01F9/127 , D01F9/133
CPC分类号： B82Y40/00 , B01J8/0055 , B01J8/006 , B01J8/26 , B01J8/28 , B01J8/382 , B01J8/42 , B01J2219/00033 , B01J2219/182 , B82Y30/00 , C01B32/162 , C01B32/164 , C01B2202/02 , C01B2202/04 , C01B2202/06 , Y10S977/742 , Y10S977/842 , Y10S977/843
摘要： The present application provides multistage and multilayer reactors useful for the efficient and continuous production of carbon nanotubes and methods of using the apparatus in the preparation of carbon nanotubes. In one aspect, the multistage reactors include an array of interconnected fluidized-bed reactors. The multilayer reactors include a plurality of reaction zones.
摘要翻译：本申请提供了用于碳纳米管的有效和连续生产的多级和多层反应器以及在制备碳纳米管中使用该装置的方法。在一个方面，多级反应器包括相互连接的流化床反应器阵列。多层反应器包括多个反应区。

52. 发明申请

US20100190749A1 Benzoxazole kinase inhibitors and methods of use 有权
标题翻译：苯并恶唑激酶抑制剂及其使用方法
公开(公告)号：US20100190749A1
公开(公告)日：2010-07-29
申请号：US12586241
申请日：2009-09-17
申请人： Pingda Ren , Yi Liu , Troy Edward Wilson , Liansheng Li , Katrina Chan
发明人： Pingda Ren , Yi Liu , Troy Edward Wilson , Liansheng Li , Katrina Chan
IPC分类号： A61K31/69 , C07D487/04 , C07D413/14 , C07F5/02 , C07D263/58 , A61P35/00 , A61P29/00 , A61P25/00 , A61P9/00
CPC分类号： A61K31/519 , A61K9/0014 , A61K9/0019 , A61K9/0053 , A61K9/0078 , A61K31/275 , A61K31/337 , A61K31/455 , A61K31/5377 , A61K31/7068 , A61K39/3955 , A61K45/06 , C07D413/04 , C07D413/14 , C07D487/04 , C07F5/025 , A61K2300/00
摘要： The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating certain protein kinases such as mTor, tyrosine kinases, and/or lipid kinases such as PI3 kinase. Also provided in the present invention are methods of using these compositions to modulate activities of one or more of these kinases, especially for therapeutic applications.
摘要翻译：本发明提供能够调节某些蛋白激酶例如mTor，酪氨酸激酶和/或脂质激酶例如PI3激酶的化学实体或其化合物及其药物组合物。本发明还提供了使用这些组合物调节这些激酶中的一种或多种，特别是用于治疗应用的活性的方法。

53. 发明申请

US20100050757A1 METHOD AND SYSTEM TO DETERMINE THE EFFICIENCY OF A DIESEL OXIDATION CATALYST 审中-公开
标题翻译：测定柴油氧化催化剂效率的方法和系统
公开(公告)号：US20100050757A1
公开(公告)日：2010-03-04
申请号：US12199882
申请日：2008-08-28
申请人： Yi Liu , Kevin Dean Sisken
发明人： Yi Liu , Kevin Dean Sisken
IPC分类号： G01M15/04
CPC分类号： F01N11/002 , F01N3/0253 , F01N3/106 , F01N13/0097 , F01N2430/085 , F01N2550/02 , F01N2560/06 , F01N2560/14 , F01N2610/03 , F01N2900/1602 , F02B37/00 , Y02T10/47
摘要： A method for determining the efficiency of a diesel oxidation catalyst (DOC) having an inlet and an outlet for the flow of an exhaust gas stream in an exhaust system used in conjunction with an electronic controlled internal combustion engine equipped with an Electronic Control Unit (ECU) having memory, comprising:determining temperature of the exhaust gas stream at the DOC inlet;determining temperature of the exhaust gas stream at the DOC outlet;determining the energy released from the DOC; andcomparing an actual change in temperature of the DOC out to a virtual temperature of the DOC out to determine whether the combustion efficiency of the DOC is below a predetermined value.
摘要翻译：一种用于确定具有用于与配备有电子控制单元（ECU）的电子控制内燃机一起使用的排气系统中的排气流的入口和出口的柴油氧化催化剂（DOC）的效率的方法），包括：确定所述DOC入口处的废气流的温度; 确定DOC出口处的废气流的温度; 确定从DOC释放的能量; 并将DOC的实际温度变化与DOC的虚拟温度进行比较，以确定DOC的燃烧效率是否低于预定值。

54. 发明申请

US20090312319A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS 有权
标题翻译：某些化学实验，组合物和方法
公开(公告)号：US20090312319A1
公开(公告)日：2009-12-17
申请号：US12503776
申请日：2009-07-15
申请人： Pingda Ren , Yi Liu , Troy Edward Wilson , Liansheng Li , Katrina Chan , Christian Rommel
发明人： Pingda Ren , Yi Liu , Troy Edward Wilson , Liansheng Li , Katrina Chan , Christian Rommel
IPC分类号： A61K31/5377 , C07D487/02 , A61K31/519 , C07D473/00 , A61K31/52 , C07D413/14 , C12N9/99 , C12N5/00 , A61P35/00 , A61P29/00 , A61P37/00 , A61P25/00 , A61P3/00 , A61P9/00 , A61P11/00
CPC分类号： A61K31/4725 , A61K31/131 , A61K31/196 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61N5/10 , A61N5/1007 , A61N2005/109 , C07D473/34 , C07D487/04 , Y02A50/401 , Y02A50/414 , Y02A50/465 , Y02P20/55
摘要： Chemical entities that modulate PI3 kinase activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities for treating diseases and conditions associated with PI3 kinase activity are described herein.
摘要翻译：本文描述了调节PI3激酶活性的化学实体，含有化学实体的药物组合物，以及使用这些化学实体治疗与PI3激酶活性相关的疾病和病症的方法。

55. 发明申请

US20090275649A1 Compositions And Methods For Identifying Modulars Of TRPV2 审中-公开
标题翻译：用于识别TRPV2模块的组合和方法
公开(公告)号：US20090275649A1
公开(公告)日：2009-11-05
申请号：US12499891
申请日：2009-07-09
申请人： Ning Qin , Yi Liu , Christopher M. Flores , Tasha Hutchinson , Michael P. Neeper
发明人： Ning Qin , Yi Liu , Christopher M. Flores , Tasha Hutchinson , Michael P. Neeper
IPC分类号： A61K31/352 , G01N33/53 , C12Q1/02 , C12P21/02 , C12N5/10 , C12N1/21 , C12N1/15 , C12N15/63 , A61K31/192 , A61K31/05 , C07K14/00 , C07H21/00
CPC分类号： G01N33/6872 , A61K31/05 , A61K31/352 , G01N33/5058 , G01N33/948 , G01N2500/02
摘要： It has now been discovered that certain cannabinoids specifically activate TRPV2 channel activity. Based on the discovery, novel compositions and methods for screening, identifying and characterizing compounds that increase or decrease the biological activity of a TRPV2.
摘要翻译：现在已经发现某些大麻素特异性地激活TRPV2通道活性。基于发现，用于筛选，鉴定和表征增加或降低TRPV2生物活性的化合物的新型组合物和方法。

56. 发明申请

US20090037179A1 Method and Apparatus for Automatically Converting Voice 有权
标题翻译：自动转换语音的方法和装置
公开(公告)号：US20090037179A1
公开(公告)日：2009-02-05
申请号：US12181553
申请日：2008-07-29
申请人： Yi Liu , Yong Qin , Qin Shi , Zhi Wei Shuang
发明人： Yi Liu , Yong Qin , Qin Shi , Zhi Wei Shuang
IPC分类号： G10L13/08
CPC分类号： G10L13/08 , G10L13/033 , G10L2021/0135
摘要： The invention proposes a method and apparatus for significantly improving the quality of voice morphing and guaranteeing the similarity of converted voice. The invention sets several standard speakers in a TTS database, and selects the voices of different standard speakers for speech synthesis according to different roles, wherein the voice of the selected standard speaker is similar to the original role to a certain extent. Then the invention further performs voice morphing on the standard voice similar to the original voice to a certain extent, in order to accurately mimic the voice of the original speaker, so as to make the converted voice closer to the original voice features while guaranteeing the similarity.
摘要翻译：本发明提出了一种显着提高语音变形质量并保证转换语音相似性的方法和装置。本发明在TTS数据库中设置几个标准扬声器，并根据不同的角色选择不同标准扬声器的语音合成语音，其中所选标准扬声器的声音在一定程度上与原始角色相似。然后本发明在一定程度上进一步对与原始语音相似的标准语音进行声音变形，以便准确地模拟原始扬声器的声音，以便使转换的语音更接近原始语音特征，同时保证相似性。

57. 发明申请

US20080007711A1 Range finder 审中-公开
标题翻译：测距仪
公开(公告)号：US20080007711A1
公开(公告)日：2008-01-10
申请号：US11387371
申请日：2006-03-23
申请人： Yi Liu
发明人： Yi Liu
IPC分类号： G01C3/08 , G02B23/24
CPC分类号： G01S7/4816 , G01C3/08 , G01S17/08 , G01S17/32
摘要： The present invention is generally directed to a range finder for measuring short and long distances via a simple, compact and stable structure without increasing the cost and the size of the device. The range finder according to the present invention comprises a light source for generating a measuring beam, a circuit for modulating the light source, a collimating objective lens, a receiving objective lens, an auxiliary lens or a group of auxiliary lenses, an optoelectronic receiver, a control and calculating unit, and a display unit.
摘要翻译：本发明一般涉及一种用于通过简单，紧凑且稳定的结构测量短距离和长距离的测距仪，而不增加设备的成本和尺寸。根据本发明的测距仪包括用于产生测量光束的光源，用于调制光源的电路，准直物镜，接收物镜，辅助透镜或一组辅助透镜，光电接收器，控制和计算单元和显示单元。

58. 发明申请

US20060258863A1 Synthesis of CCR5 antagonists 失效
标题翻译： CCR5拮抗剂的合成
公开(公告)号：US20060258863A1
公开(公告)日：2006-11-16
申请号：US11326154
申请日：2006-01-05
申请人： Xiongwei Shi , Man Zhu , William Leong , Vilas Dahanukar , Ilia Zavialov , Cecilia Proletei , Shannon Zhao , Hong-Chang Lee , Yi Liu , Hoa Nguyen , Wenxue Wu , Bosco D'Sa , Feng Liang , Loc Tran
发明人： Xiongwei Shi , Man Zhu , William Leong , Vilas Dahanukar , Ilia Zavialov , Cecilia Proletei , Shannon Zhao , Hong-Chang Lee , Yi Liu , Hoa Nguyen , Wenxue Wu , Bosco D'Sa , Feng Liang , Loc Tran
IPC分类号： C07D403/14
CPC分类号： C07D211/96 , C07D211/26 , C07D401/14
摘要： The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.
摘要翻译：本发明涉及4- [4 - [（R） - [1- [环丙基磺酰基] -4-哌啶基]（3-氟苯基）甲基] -3（S） - 甲基-1-哌嗪基] 1 - [（4,6-二甲基-5-嘧啶基）羰基] -4-甲基哌啶]，以及通过新途径从容易获得的起始原料中间产物。

59. 发明申请

US20060157327A1 Rotating button and electronic device utilizing the same 审中-公开
标题翻译：旋转按钮和利用它的电子设备
公开(公告)号：US20060157327A1
公开(公告)日：2006-07-20
申请号：US11335096
申请日：2006-01-18
申请人： Chi Chou , Yi Liu
发明人： Chi Chou , Yi Liu
IPC分类号： H01H19/00
CPC分类号： H01H19/11 , H01H25/065
摘要： An electronic device includes a housing and a rotating button disposed on the housing. A first rotation member includes a first protrusion. A second rotation member is connected to the first rotation member in a rotatable manner. When the second rotation member is rotated, the first rotation member is rotated along with the second rotation member. A moving member is moveably disposed between the first rotation member and the second rotation member, and includes a second protrusion. The shape of the second protrusion corresponds to the shape of the first protrusion so that the moving member can be simply stable at an idle position. An elastic member is disposed between the moving member and the second rotation member.
摘要翻译：电子设备包括壳体和设置在壳体上的旋转按钮。第一旋转构件包括第一突起。第二旋转构件以可旋转的方式连接到第一旋转构件。当第二旋转构件旋转时，第一旋转构件与第二旋转构件一起旋转。移动构件可移动地设置在第一旋转构件和第二旋转构件之间，并且包括第二突起。第二突起的形状对应于第一突起的形状，使得移动部件能够在空闲位置简单地稳定。弹性构件设置在移动构件和第二旋转构件之间。

60. 发明申请

US20050209285A1 Compounds and compositions as protein kinase inhibitors 失效
标题翻译：化合物和组合物作为蛋白激酶抑制剂
公开(公告)号：US20050209285A1
公开(公告)日：2005-09-22
申请号：US10956880
申请日：2004-10-01
申请人： Nathanael Gray , Jiqing Jiang , Yi Liu , Ruo Steensma
发明人： Nathanael Gray , Jiqing Jiang , Yi Liu , Ruo Steensma
IPC分类号： A61K20060101 , A61K31/4439 , C07D401/02 , C07D401/04 , C07D405/14 , C07D43/02
CPC分类号： C07D401/04 , C07D401/02 , C07D405/12 , C07D405/14
摘要： The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, lck, SAPK2α, p38, TGFβ, KDR, c-Kit, b-RAF, c-RAF, FLT1 and FLT4 kinases.
摘要翻译：本发明提供了一类新颖的化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的激酶活性相关的疾病或病症的方法，特别是涉及Abl，BCR-Abl异常活化的疾病或病症，PDGF-R，lck，SAPK2alpha，p38，TGFbeta，KDR，c-Kit，b-RAF，c-RAF，FLT1和FLT4激酶。

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