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51. 发明申请

US20100190757A1 COMBINATION PREPARATION FOR ORAL CONTREACEPTION AND ORAL THERAPY OF DYSFUNCTIONAL UTERINE BLEEDING CONTAINING ESTRADIOL VALERATE AND DIENOGEST AND METHOD OF USING SAME 审中-公开
标题翻译：用于口服避孕的口服制剂和含有雌激素的异常子宫切除术的口服治疗及其使用方法
公开(公告)号：US20100190757A1
公开(公告)日：2010-07-29
申请号：US12726804
申请日：2010-03-18
申请人： Susan Zeun , Pol Boudes , Angelo Secci , Jan Nedrikat , Holger Zimmermann
发明人： Susan Zeun , Pol Boudes , Angelo Secci , Jan Nedrikat , Holger Zimmermann
IPC分类号： A61K31/565 , A61P15/18
CPC分类号： A61K31/56 , A61K31/57
摘要： The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase consisting of 2 daily dosage units, each containing 3 mg of estradiol valerate or
摘要翻译：用于口腔治疗功能障碍性子宫出血和口服避孕药的多相组合制剂含有由2个日剂量单位组成的第一相，每个剂量单位含有3mg戊酸雌二醇或<3mg雌二醇; 第二组由第一组5个每日剂量单位组成，每组由2mg的地诺孕酮与2mg戊酸雌二醇或2mg雌二醇的组合组成，第二组由17个日剂量单位组成，每组包含的3mg的地诺孕酮与2mg戊酸雌二醇或<2mg雌二醇的组合; 第三阶段由2个日剂量单位组成，每个单位含有1毫克戊酸雌二醇或<1毫克雌二醇; 另一个阶段由药物无害安慰剂的2个日剂量单位组成。

52. 发明申请

US20070111977A1 COMBINATION PREPARATION FOR ORAL CONTRACEPTION AND ORAL THERAPY OF DYSFUNCTIONAL UTERINE BLEEDING CONTAINING ESTRADIOL VALERATE AND DIENOGEST AND METHOD OF USING SAME 有权
标题翻译：用于口服合同和含有雌激素的功能性尿液排泄物的口服治疗的组合制剂及其使用方法
公开(公告)号：US20070111977A1
公开(公告)日：2007-05-17
申请号：US11609705
申请日：2006-12-12
申请人： Susan Zeun , Pol Boudes , Angelo Secci , Jan Endrikat , Holger Zimmermann
发明人： Susan Zeun , Pol Boudes , Angelo Secci , Jan Endrikat , Holger Zimmermann
IPC分类号： A61K31/57 , A61K31/56
CPC分类号： A61K31/56 , A61K31/57
摘要： The multiphase combination preparation for oral therapy of dysfunctional uterine bleeding and for oral contraception contains a first phase consisting of 2 daily dosage units, each containing 3 mg of estradiol valerate or
摘要翻译：用于口腔治疗功能障碍性子宫出血和口服避孕药的多相组合制剂含有由2个日剂量单位组成的第一相，每个剂量单位含有3mg戊酸雌二醇或<3mg雌二醇; 第二组由第一组5个每日剂量单位组成，每组由2mg的地诺孕酮与2mg戊酸雌二醇或2mg雌二醇的组合组成，第二组由17个日剂量单位组成，每组包含的3mg的地诺孕酮与2mg戊酸雌二醇或<2mg雌二醇的组合; 第三阶段由2个日剂量单位组成，每个单位含有1毫克戊酸雌二醇或<1毫克雌二醇; 另一个阶段由药物无害安慰剂的2个日剂量单位组成。

53. 发明授权

US07092326B2 Player for storage media 有权
标题翻译：播放器用于存储媒体
公开(公告)号：US07092326B2
公开(公告)日：2006-08-15
申请号：US10491251
申请日：2002-09-20
申请人： Volker Becker , Holger Zimmermann
发明人： Volker Becker , Holger Zimmermann
IPC分类号： G11B7/00
CPC分类号： G11B27/002 , G11B27/105 , G11B27/11 , G11B27/34 , G11B2220/2529 , G11B2220/2545 , G11B2220/2562 , G11B2220/65
摘要： A player for storage media having a number of data groups is provided, which player enables a data group to be selected in a clearly organized way, particularly when a large number of data groups is stored on such a storage medium. In this context, a read head is provided for reading out the data of a first storage medium, and a read-head control is provided for positioning the read head in the area of a data group to be played, which data group is stored on the first storage medium. In addition, an input unit is provided where, on the one hand, various storage media and, on the other hand, various data groups, are selectable on a selected storage medium to be played. A conversion device is provided, which, in response to the number of data groups on the first storage medium exceeding a predefined value, forms at least two subsets from the number of data groups of the first storage medium, each of these subsets at the input unit being selectable as a different storage medium. The conversion device drives the read-head control as a function of the subset selected as storage medium at the input unit, to position the read head.
摘要翻译：提供了具有多个数据组的存储介质的播放器，该播放器使得能够以清晰有组织的方式选择数据组，特别是当在这种存储介质上存储大量数据组时。在这种情况下，提供读头以读出第一存储介质的数据，并且提供读头控制用于将读头定位在要播放的数据组的区域中，该数据组被存储在第一存储介质。此外，提供了一个输入单元，其中一方面各种存储介质，另一方面，各种数据组可在所选择的要播放的存储介质上选择。提供了一种转换装置，其响应于第一存储介质上的数据组的数量超过预定值，从第一存储介质的数据组的数量形成至少两个子集，这些子集中的每一个在输入端单元可选择为不同的存储介质。转换装置驱动读取头控制作为在输入单元处被选择为存储介质的子集的函数，以定位读取头。

54. 发明授权

US07053077B1 Use of biogenic estrogen sulfamates for hormone replacement therapy 有权
标题翻译：使用生物源性雌激素氨基磺酸盐治疗激素替代疗法
公开(公告)号：US07053077B1
公开(公告)日：2006-05-30
申请号：US09744574
申请日：1999-05-13
申请人： Walter Elger , Pekka Lähteenmäki , Matti Lehtinen , Gudrun Reddersen , Holger Zimmermann , Michael Oettel , Sigfrid Schwarz
发明人： Walter Elger , Pekka Lähteenmäki , Matti Lehtinen , Gudrun Reddersen , Holger Zimmermann , Michael Oettel , Sigfrid Schwarz
IPC分类号： A61K31/56
CPC分类号： A61K31/566 , A61K31/565 , A61K31/57 , Y10S514/874 , A61K2300/00
摘要： The invention relates to the use of biogenic estrogen sulfamates for the oral discontinuous application for hormone replacement therapy (HRT). The discontinuous administration takes place in intervals ranging from 2 to 40 days. The invention also provides the additional application of gestagens, preferably continuously in the form of an implant or in the form of an intrauterine releasing system (IUD). Estrone sulfamate, estradiol sulfamate or an N-acyl sulfamate of estrone, estradiol or estriol having up to 7 C-atoms in the acyl chain, or a combination comprised of two or more of said active ingredients are used as biogenic estrogen sulfamates.
摘要翻译：本发明涉及用于激素替代治疗（HRT）的口服不连续应用的生物源性雌激素氨基磺酸盐的用途。不连续给药时间间隔为2至40天。本发明还提供了孕妇的额外应用，优选连续地以植入物的形式或以子宫内释放系统（IUD）的形式。氨基磺酸氨基磺酸酯，氨基磺酸雌二醇酯或酰基链中具有至多7个C原子的雌酮，雌二醇或雌三醇的N-酰基氨基磺酸酯或由两种或更多种所述活性成分组成的组合物用作生物来源的雌激素亚磺酸盐。

55. 发明授权

US06977083B1 Bioadhesive tablet containing testosterone/testosterone ester mixtures and method for producing a predetermined testosterone time-release profile with same 失效
标题翻译：含有睾酮/睾酮酯混合物的生物粘附片剂和用于产生具有相同的预定睾酮时间释放特性的方法
公开(公告)号：US06977083B1
公开(公告)日：2005-12-20
申请号：US09806639
申请日：1999-09-30
申请人： Doris Huebler , Guenter Kaufmann , Michael Oettel , Holger Zimmermann , Michael Dittgen , Sabine Fricke , Manfred Boese , Ralf Ladwig , Sven Claussen , Carsten Timpe
发明人： Doris Huebler , Guenter Kaufmann , Michael Oettel , Holger Zimmermann , Michael Dittgen , Sabine Fricke , Manfred Boese , Ralf Ladwig , Sven Claussen , Carsten Timpe
IPC分类号： A61F13/00 , A61K9/00
CPC分类号： A61K9/006
摘要： The method of making a bioadhesive tablet for controlling testosterone blood level, especially in elderly men suffering from partial androgen deficiency, includes spray-drying an alcoholic solution or suspension of testosterone and at least one testosterone ester, preferably in a ratio of 1:10 to 1:1.5, separately or together, with an organic polymer and optionally one or more auxiliary ingredient to form an active ingredient premix. Then various other auxiliary ingredients are mixed, as needed, with the active ingredient premix to form the bioadhesive tablet with an active ingredient layer and an adhesive layer. The active ingredient layer contains an effective amount of the active ingredient premix. The adhesive layer includes auxiliary ingredients including the bioadhesive polymer. The bioadhesive tablet may be buccally administered to provide a predetermined timed release profile of testosterone, advantageously varying according to a circadian rhythm.
摘要翻译：制备用于控制睾酮血液水平的生物粘附片剂的方法，特别是在患有部分雄激素缺乏症的老年男性中，包括将睾酮和至少一种睾酮酯的醇溶液或悬浮液喷雾干燥，优选1:10至 1：1.5，分别或一起与有机聚合物和任选的一种或多种辅助成分形成活性成分预混物。然后根据需要将各种其它辅助成分与活性成分预混合物混合以形成具有活性成分层和粘合剂层的生物粘附片剂。活性成分层含有有效量的活性成分预混物。粘合层包括辅助成分，包括生物粘附聚合物。生物粘附片剂可以经口给药以提供睾酮的预定定时释放曲线，其有利地根据昼夜节律改变。

56. 发明授权

US06526003B1 Playback device for disc-shaped recording media 有权
标题翻译：磁盘设备能够播放音频光盘和存储光盘
公开(公告)号：US06526003B1
公开(公告)日：2003-02-25
申请号：US09601731
申请日：2000-10-20
申请人： Jens Maier , Holger Zimmermann
发明人： Jens Maier , Holger Zimmermann
IPC分类号： G11B2108
CPC分类号： G11B27/105 , G11B19/02 , G11B27/329 , G11B2220/213 , G11B2220/2545
摘要： A playback device for disk-shaped recording media is proposed, which makes it possible to skip over storage data groups on audio disks. The playback device includes a scanning device and a device for evaluating content data recorded in a start-up area on the recording medium. The recording medium inserted in the playback device is recognized as a storage disk or as an audio disk, depending on the evaluation of the content data. In the event that a storage disk is recognized, a playback process is terminated, and in the event an audio disk is recognized, the scanning device skips to a just addressed title of the audio disk. The scanning device, during the playback of a title of the audio disk, scans coded supplemental information data recorded with respect to this title. The evaluation device, on the basis of the supplemental information, recognizes whether the title just played is an audio data group or a storage data group. In the event that a storage data group is recognized, the scanning device skips to a different title.
摘要翻译：提出了一种用于盘形记录介质的回放装置，可以跳过音频盘上的存储数据组。回放装置包括扫描装置和用于评估记录在记录介质上的启动区域中的内容数据的装置。根据内容数据的评价，插入回放装置中的记录介质被识别为存储盘或音频盘。在存储盘被识别的情况下，重放过程终止，并且在识别到音频盘的情况下，扫描设备跳到音频盘的刚好寻址的标题。扫描装置在播放音频盘的标题期间扫描关于该标题记录的编码补充信息数据。评估装置基于补充信息识别刚刚播放的标题是音频数据组还是存储数据组。在存储数据组被识别的情况下，扫描设备跳过不同的标题。

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