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51. 发明申请

US20050079483A1 Novel method of diagnosing, monitoring, and staging prostate cancer 失效
标题翻译：诊断，监测和分期前列腺癌的新方法
公开(公告)号：US20050079483A1
公开(公告)日：2005-04-14
申请号：US10939560
申请日：2004-09-13
申请人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
发明人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/156
摘要： The present invention provides a new method for detecting, diagnosing, monitoring, staging and prognosticating prostate cancer.
摘要翻译：本发明提供了一种用于检测，诊断，监测，分期和预测前列腺癌的新方法。

52. 发明授权

US06846650B2 Compositions and methods relating to lung specific genes and proteins 失效
标题翻译：与肺特异性基因和蛋白质有关的组成和方法
公开(公告)号：US06846650B2
公开(公告)日：2005-01-25
申请号：US10002344
申请日：2001-10-25
申请人： Herve E. Recipon , Yongming Sun , Sei-Yu Chen , Chenghua Liu , Leah R. Turner
发明人： Herve E. Recipon , Yongming Sun , Sei-Yu Chen , Chenghua Liu , Leah R. Turner
IPC分类号： G01N33/53 , A61K38/00 , A61K39/00 , A61K39/395 , A61K48/00 , A61P11/00 , A61P35/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/566 , G01N33/574 , C07H21/04
CPC分类号： C07K14/47 , A61K38/00
摘要： The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
摘要翻译：本发明涉及存在于正常和肿瘤性肺细胞中的新鉴定的核酸和多肽，包括核酸和多肽的片段，变体和衍生物。本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。本发明还涉及包含本发明的核酸，多肽，抗体，变体，衍生物，激动剂和拮抗剂以及使用这些组合物的方法的组合物。这些用途包括识别，诊断，监测，分期，成像和治疗肺中的肺癌和非癌性疾病状态，识别肺组织，监测和/或设计本发明多肽的激动剂和拮抗剂。用途还包括基因治疗，转基因动物和细胞的生产以及用于治疗和研究的工程化肺组织的生产。

53. 发明授权

US06737040B1 Method and antibody for imaging breast cancer 失效
标题翻译：用于成像乳腺癌的方法和抗体
公开(公告)号：US06737040B1
公开(公告)日：2004-05-18
申请号：US09762027
申请日：2001-08-06
申请人： Yongming Sun , Herve Recipon , Robert Cafferkey
发明人： Yongming Sun , Herve Recipon , Robert Cafferkey
IPC分类号： A61K4900
CPC分类号： G01N33/57415 , A61K49/16 , A61K51/1051 , C07K16/3015
摘要： The present invention provides a new method of detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating breast cancer.
摘要翻译：本发明提供了检测，诊断，监测，分期，预后，成像和治疗乳腺癌的新方法。

54. 发明申请

US20120319311A1 UV STERILIZATION CHAMBER FOR A HUMIDIFIER 审中-公开
标题翻译：一种除湿器紫外杀菌室
公开(公告)号：US20120319311A1
公开(公告)日：2012-12-20
申请号：US13002598
申请日：2010-10-20
申请人： Francis C Nutter , Zhijing Wang , Robert Zhao , Edisen Lu , Yongming Sun , Sean Wang , Christopher S. Kanel
发明人： Francis C Nutter , Zhijing Wang , Robert Zhao , Edisen Lu , Yongming Sun , Sean Wang , Christopher S. Kanel
IPC分类号： F24F6/02 , A61L2/10
CPC分类号： F24F13/00 , C02F1/32 , F24F6/02 , F24F6/043 , F24F13/20 , F24F2003/1667 , F24F2006/006 , F24F2006/008
摘要： A UV sterilization chamber is provided to a humidifier having a water reservoir, a humidifying element and a pathway for directing water provided by the water reservoir to the humidifying element of the humidifier. The pathway is provided in a humidifier base, over which a humidifier enclosure is removably placed. The UV sterilization chamber includes a serpentine portion of the pathway and a UV radiation source positioned for illuminating the portion of the pathway with UV light. Upwardly-directed projections in the base border a perimeter of the pathway; and a downwardly-directed projection of the UV radiation source extends between the upwardly-directed projections when the enclosure is mated with the base, thereby locating the UV radiation source over the portion of the pathway. A switch disables the UV radiation source when the enclosure is removed from the base.
摘要翻译： UV加压器设置在具有储水器，加湿元件和用于将由储水器提供的水引导到加湿器的加湿元件的通道的加湿器中。该通道设置在加湿器基座中，加湿器外壳可移除地放置在该加湿器基座上。 UV消毒室包括路径的蛇形部分和定位成用UV光照射路径部分的UV辐射源。在基部边界中的向上指向的突起在通路的周边; 并且当外壳与基座配合时，UV辐射源的向下指向的突出部在向上指向的突起之间延伸，从而将UV辐射源定位在路径的该部分上。当外壳从基座上拆下时，开关会禁用紫外线辐射源。

55. 发明申请

US20100167278A1 Novel Method of Diagnosing, Monitoring, and Staging Prostate Cancer 审中-公开
标题翻译：诊断，监测和分期前列腺癌的新方法
公开(公告)号：US20100167278A1
公开(公告)日：2010-07-01
申请号：US12341553
申请日：2008-12-22
申请人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
发明人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/156
摘要： The present invention provides a new method for detecting, diagnosing, monitoring, staging and prognosticating prostate cancer.
摘要翻译：本发明提供了一种用于检测，诊断，监测，分期和预测前列腺癌的新方法。

56. 发明申请

US20100058178A1 Network-Based Method and Apparatus for Filtering Junk Messages 有权
标题翻译：基于网络的垃圾邮件过滤方法和装置
公开(公告)号：US20100058178A1
公开(公告)日：2010-03-04
申请号：US12443371
申请日：2007-08-27
申请人： Qijiang Dong , Yongming Sun
发明人： Qijiang Dong , Yongming Sun
IPC分类号： G06F15/16 , G06F17/24
CPC分类号： G06Q10/107 , H04L51/12
摘要： The present invention discloses a network-based method and system for filtering a junk message. The method includes the following procedures: word-segmenting a target message to obtain characteristic elements within the target message; obtaining probabilities of the characteristic elements in the target message according to a predefined keyword library, the keyword library being updated periodically; and accumulating the probabilities of the characteristic elements in the target message, comparing accumulated probabilities with a predetermined threshold, and concluding the target message is a junk message if the result is greater than the predetermined threshold. Using a predefined keyword library for verification of a target message avoids time delay and system resource waste caused by massive and complicated computations during message verification in existing technologies, thus satisfying the requirement of real-time filtering of junk messages.
摘要翻译：本发明公开了一种用于过滤垃圾信息的基于网络的方法和系统。该方法包括以下步骤：对目标消息进行字分割以获得目标消息内的特征元素; 根据预定义的关键字库获取目标消息中的特征元素的概率，定期更新关键字库; 并且累积目标消息中的特征元素的概率，将累积概率与预定阈值进行比较，并且如果结果大于预定阈值，则结束目标消息是垃圾消息。使用预定义的关键字库来验证目标消息可以避免在现有技术的消息验证过程中大量复杂的计算造成的时间延迟和系统资源浪费，从而满足对垃圾邮件的实时过滤的要求。

57. 发明申请

US20050208546A1 Compositions and methods relating to colon secific genes and proteins 失效
标题翻译：与结肠分泌基因和蛋白质有关的组成和方法
公开(公告)号：US20050208546A1
公开(公告)日：2005-09-22
申请号：US11042241
申请日：2005-01-25
申请人： Yongming Sun , Herve Recipon , Malavika Ghosh , Chenghua Liu
发明人： Yongming Sun , Herve Recipon , Malavika Ghosh , Chenghua Liu
IPC分类号： G01N33/53 , A61K38/00 , A61K39/00 , A61K39/395 , A61K48/00 , A61P35/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12Q1/68 , G01N33/566 , A61K38/17 , C07H21/04 , C07K14/82 , G01N33/574
CPC分类号： C07K14/47 , A61K38/00 , A61K2039/505 , A61K2039/53
摘要： The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic colon cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating colon cancer and non-cancerous disease states in colon tissue, identifying colon tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered colon tissue for treatment and research.
摘要翻译：本发明涉及存在于正常和肿瘤性结肠细胞中的新鉴定的核酸和多肽，包括核酸和多肽的片段，变体和衍生物。本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。本发明还涉及包含本发明的核酸，多肽，抗体，变体，衍生物，激动剂和拮抗剂以及使用这些组合物的方法的组合物。这些用途包括鉴定，诊断，监测，分期，成像和治疗结肠组织中的结肠癌和非癌性疾病状态，鉴定结肠组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。用途还包括基因治疗，转基因动物和细胞的生产以及用于治疗和研究的工程结肠组织的生产。

58. 发明申请

US20050208062A1 Compositions and methods relating to hepatic specific genes and proteins 审中-公开
标题翻译：与肝脏特异性基因和蛋白质有关的组成和方法
公开(公告)号：US20050208062A1
公开(公告)日：2005-09-22
申请号：US10499065
申请日：2002-12-20
申请人： Yongming Sun , Chenghua Liu
发明人： Yongming Sun , Chenghua Liu
IPC分类号： A61K38/00 , A61K39/00 , C07H21/04 , C07K14/47 , C07K14/705 , C12N1/21 , C12N15/12 , C12Q1/68 , G01N33/574
CPC分类号： C07K14/4748 , A61K38/00 , C12Q1/6886 , C12Q2600/158 , G01N33/57438
摘要： The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic hepatic cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating hepatic cancer and non-cancerous disease states in hepatic, identifying hepatic tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered hepatic tissue for treatment and research.
摘要翻译：本发明涉及存在于正常和肿瘤性肝细胞中的新鉴定的核酸分子和多肽，包括核酸和多肽的片段，变体和衍生物。本发明还涉及本发明多肽的抗体，以及本发明多肽的激动剂和拮抗剂。本发明还涉及含有本发明的核酸分子，多肽，抗体，激动剂和拮抗剂以及使用这些组合物的方法的组合物。这些用途包括识别，诊断，监测，分期，成像和治疗肝脏中的肝癌和非癌性疾病状态，鉴定肝组织，监测和鉴定和/或设计本发明多肽的激动剂和拮抗剂。用途还包括基因治疗，转基因动物和细胞的生产以及用于治疗和研究的工程化肝组织的生产。

59. 发明授权

US06902890B1 Method of diagnosing monitoring, staging, imaging and treating cancer 失效
标题翻译：诊断监测，分期，成像和治疗癌症的方法
公开(公告)号：US06902890B1
公开(公告)日：2005-06-07
申请号：US09705500
申请日：2000-11-03
申请人： Herve Recipon , Roberto A. Macina , Sei-Yu Chen , Yongming Sun
发明人： Herve Recipon , Roberto A. Macina , Sei-Yu Chen , Yongming Sun
IPC分类号： A61K39/00 , A61K49/16 , A61K51/10 , C07K16/30 , C12Q1/68 , G01N33/50 , G01N33/53 , G01N33/574
CPC分类号： G01N33/57423 , A61K39/0011 , A61K49/16 , A61K51/1054 , A61K2039/505 , C07K16/3023 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , G01N33/574
摘要： The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating cancer.
摘要翻译：本发明提供了检测，诊断，监测，分期，预后，成像和治疗癌症的新方法。

60. 发明授权

US06861215B1 Method of diagnosing, monitoring, and staging prostate cancer 失效
标题翻译：诊断，监测和分期前列腺癌的方法
公开(公告)号：US06861215B1
公开(公告)日：2005-03-01
申请号：US09700700
申请日：1999-05-12
申请人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
发明人： Shujath Ali , Susana Salceda , Yongming Sun , Robert Cafferkey
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/156
摘要： The present invention provides a new method for detecting, diagnosing, monitoring, staging and prognosticating prostate cancer.
摘要翻译：本发明提供了一种用于检测，诊断，监测，分期和预测前列腺癌的新方法。

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