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51. 发明申请

US20050243379A1 Document processing system with improved image quality assurance 有权
标题翻译：文件处理系统具有改进的图像质量保证
公开(公告)号：US20050243379A1
公开(公告)日：2005-11-03
申请号：US10837344
申请日：2004-04-30
申请人： Robert Klein , Craig Lapan , George Reasoner
发明人： Robert Klein , Craig Lapan , George Reasoner
IPC分类号： G06K15/00 , G07F19/00
CPC分类号： G06Q20/042 , G06Q20/1085 , G07F19/202 , Y10S707/99931 , Y10S707/99937 , Y10S707/99945
摘要： A document processing system comprising an image capture subsystem for capturing selected image metrics and at least one image rendition from a plurality of documents and for determining if at least one of the selected image metrics for any of the at least one image rendition does not successfully compare against preselected image quality metric threshold values. An image quality flag is generated for any of the at least one image rendition if it does not successfully compare, and a record entry for each imaged document having at least one flagged image rendition is created in an image quality flag file. An image index file for individually accessing the image renditions is modified to include a reference to the corresponding image quality flag file record entry The document processing system may optionally compare selected document metrics against preselected document metrics in a similar manner. Image defects in the plurality of documents can be identified by examining the record entries in the image quality flag file.
摘要翻译：一种文档处理系统，包括用于从多个文档捕获所选择的图像度量和至少一个图像再现的图像捕获子系统，并且用于确定所述至少一个图像再现中的任一个的所选图像度量中的至少一个是否未成功比较针对预选图像质量度量阈值。如果没有成功比较，则生成用于至少一个图像再现的任何图像质量标记，并且在图像质量标记文件中创建具有至少一个标记图像再现的每个成像文档的记录条目。用于单独访问图像再现的图像索引文件被修改为包括对相应图像质量标志文件记录条目的引用。文档处理系统可以可选地以类似的方式将所选择的文档度量与预先选择的文档度量进行比较。可以通过检查图像质量标志文件中的记录条目来识别多个文档中的图像缺陷。

52. 发明授权

US06413936B1 Glycomimetics as selectin antagonists and pharmaceuticals having antiinflammatory activity 失效
标题翻译：作为选择素拮抗剂的Glycomimetics和具有抗炎活性的药物
公开(公告)号：US06413936B1
公开(公告)日：2002-07-02
申请号：US08739855
申请日：1996-10-30
申请人： Wolfgang Schmidt , Ulrich Sprengard , Gerhard Kretzschmar , Robert Klein , Horst Kunz
发明人： Wolfgang Schmidt , Ulrich Sprengard , Gerhard Kretzschmar , Robert Klein , Horst Kunz
IPC分类号： A61K3170
CPC分类号： C07D405/10 , A61K38/00 , C07D307/20 , C07D309/10 , C07D407/06 , C07K9/001
摘要： The invention relates to novel mimetics of the tetrasaccharides sialyl-Lewis-X and sialyl-Lewis-A having an improved action as inhibitors of cell adhesion, to a process for the preparation of these compounds and to their use as pharmacological active compounds and diagnostic agents.
摘要翻译：本发明涉及具有作为细胞粘附抑制剂的改善作用的四糖唾液酸 - 路易斯-X和唾液酸 - 路易斯-A的新型模拟物，制备这些化合物的方法及其作为药物活性化合物和诊断剂的用途。

53. 发明授权

US5420941A Parallel pipelined image processor 失效
标题翻译：并行流水线图像处理器
公开(公告)号：US5420941A
公开(公告)日：1995-05-30
申请号：US123531
申请日：1993-09-17
申请人： Joseph M. Capo , Robert D'Aoust , Debora Y. Grosse , Robert Klein , Ravi K. Nigam , George E. Reasoner, Jr. , David C. Williams
发明人： Joseph M. Capo , Robert D'Aoust , Debora Y. Grosse , Robert Klein , Ravi K. Nigam , George E. Reasoner, Jr. , David C. Williams
IPC分类号： G06T1/20 , G06K9/60
CPC分类号： G06T1/20
摘要： A pipelined image processor generates an image of the information contained on first and second portions of a document. The pipelined image processor includes a first pipe for processing information contained on the first portion of the document, and second pipe for processing information contained on the second portion of the document. The pipes receive the output from two camera assemblies which are used for generating an electrical signal in response to information contained on the document, an image digitizer for generating digitized information from the electrical signal by the means for generating an electrical signal. In addition, both pipes also include a resequencer for generating resequenced information from the digitized information, as well as an image processor for generating processed information from the resequenced information. Finally, the first and second pipes include a transposer/compressor assembly for generating transposed and compressed information from the processed information, and a compressed data buffer for storing the transposed and compressed information.
摘要翻译：流水线图像处理器生成包含在文档的第一和第二部分上的信息的图像。流水线图像处理器包括用于处理包含在文档的第一部分上的信息的第一管道和用于处理包含在文档的第二部分上的信息的第二管道。管道接收来自两个照相机组件的输出，这些照相机组件用于响应于文档中包含的信息而产生电信号，图像数字转换器用于通过用于产生电信号的装置从电信号产生数字化信息。此外，两个管道还包括用于从数字化信息生成可重新排序的信息的再同步器，以及用于从重新排序的信息产生处理的信息的图像处理器。最后，第一和第二管道包括用于从经处理的信息产生转置和压缩信息的转移器/压缩机组件，以及用于存储转置和压缩信息的压缩数据缓冲器。

54. 发明授权

US5157740A Method for background suppression in an image data processing system 失效
标题翻译：图像数据处理系统背景抑制方法
公开(公告)号：US5157740A
公开(公告)日：1992-10-20
申请号：US653403
申请日：1991-02-07
申请人： Robert Klein , Karen A. Wilds , Michael Higgins-Luthman , David C. Williams
发明人： Robert Klein , Karen A. Wilds , Michael Higgins-Luthman , David C. Williams
IPC分类号： G06K9/38
CPC分类号： G06K9/38 , G06K2209/01
摘要： A digital image preprocessing method for eliminating background patterns and scenes from digitized gray level document image data. The method accepts multi-gray level image data as input and produces a gray level output image containing a "white" background. Document image backgrounds are eliminated (or suppressed) by computing a separate (and typically different) threshold value for each gray level pixel of the original document image. Input image pixels whose gray level is greater (brighter) than the threshold value are assumed to be background picture data and are modified to be "white" pixels in the output image. The pixel threshold value is determined dynamically pixel-to-pixel based on gray level pixel data observed within the input image. Additionally, the pixel threshold can be automatically controlled to insure retention of written and/or printed information present in the input image. Threshold control is accomplished by specifying a print contrast signal (PCS) parameter to the image preprocessing method. Documents which might use this preprocessing technique include, but are not limited to, bank checks, remittance documents, charge card slips, deposit slips and similar type financial documents.
摘要翻译：一种用于从数字化灰度文档图像数据中消除背景图案和场景的数字图像预处理方法。该方法接受多灰度级图像数据作为输入，并产生包含“白色”背景的灰度级输出图像。通过为原始文档图像的每个灰度级像素计算单独的（并且通常不同的）阈值来消除（或抑制）文档图像背景。其灰度比阈值大（亮度）的输入图像像素被假设为背景图像数据，并且在输出图像中被修改为“白色”像素。基于输入图像中观察到的灰度级像素数据，动态地像素到像素确定像素阈值。此外，可以自动控制像素阈值，以确保输入图像中存在的写入和/或打印信息的保留。通过为图像预处理方法指定打印对比度信号（PCS）参数来实现阈值控制。可能使用这种预处理技术的文件包括但不限于银行支票，汇款单，收费卡单，存单和类似类型的财务文件。

55. 发明授权

US11782726B1 Serial bootstrap 有权
公开(公告)号：US11782726B1
公开(公告)日：2023-10-10
申请号：US17036604
申请日：2020-09-29
申请人： Barak Wasserstrom , Idan Saar , Robert Klein
发明人： Barak Wasserstrom , Idan Saar , Robert Klein
IPC分类号： G06F9/4401
CPC分类号： G06F9/4401
摘要： Approaches in accordance with various embodiments can be used to provide bootstrap data for a computing device, such as a system on chip (SoC). In particular, various embodiments can use one or more shift registers to receive bits of a sequence of bootstrap data in parallel. Individual bits of this bootstrap data sequence can then be provided to the SoC, from the shift register(s), serially and using a single input. Such an approach prevents the need for multiple bootstrap pins on the SoC, as well as the need to multiplex those pins for use with other external devices.

56. 发明授权

US09084171B2 Predictive hard and soft handover 有权
标题翻译：预测硬和软切换
公开(公告)号：US09084171B2
公开(公告)日：2015-07-14
申请号：US12557254
申请日：2009-09-10
申请人： Robert Klein
发明人： Robert Klein
IPC分类号： H04W36/00 , H04W36/30 , H04W36/24 , H04W72/08 , H04B17/00
CPC分类号： H04W36/30 , H04B17/10 , H04B17/15 , H04B17/318 , H04B17/336 , H04W36/00 , H04W36/24 , H04W72/085
摘要： Methods and apparatus that facilitate predictive hard and soft handover are presented herein. A measurement component can measure signal strength data associated with a source cell and one or more target cells. One or more linear regression lines can be computed based on the signal strength data. Rates of at least one of an increase or a decrease in the signal strength data per unit of time can be determined based on a slope of the one or more linear regression lines—the slope can comprise a change in signal strength data per unit of time. A time to trigger at least one of a hard or soft handover can be triggered based on the rates.
摘要翻译：本文介绍了促进预测性硬切换和软切换的方法和装置。测量组件可以测量与源小区和一个或多个目标小区相关联的信号强度数据。可以基于信号强度数据来计算一个或多个线性回归线。可以基于一个或多个线性回归线的斜率来确定每单位时间的信号强度数据的增加或减少中的至少一个的速率 - 该斜率可以包括每单位时间的信号强度数据的变化。可以基于速率触发触发硬切换或软切换中的至少一个的时间。

57. 发明授权

US08688387B2 Method for the determination of intra- and intermolecular interactions in aqueous solution 有权
标题翻译：测定水溶液中分子间和分子间相互作用的方法
公开(公告)号：US08688387B2
公开(公告)日：2014-04-01
申请号：US13366491
申请日：2012-02-06
申请人： Gudrun Lange , Robert Klein , Juergen Albrecht , Matthias Rarey , Ingo Reulecke
发明人： Gudrun Lange , Robert Klein , Juergen Albrecht , Matthias Rarey , Ingo Reulecke
IPC分类号： G01N33/48 , G06G7/58
CPC分类号： G06F19/701 , G06F19/16 , Y10T436/143333
摘要： The present invention relates to the determination of intra- or intermolecular interaction between molecules in aqueous solution, the method comprising the steps of: (a) determining the dehydration of all atoms in the intermolecular interface, (b) adding the vacuum hydrogen bond energy, and (c) further adding the change in the free enthalpy of the interacting partners upon their interaction. The obtained results can be used for the prediction if and to what extent two molecules of various origin fit to each other.
摘要翻译：本发明涉及水溶液中分子间或分子间相互作用的测定，该方法包括以下步骤：（a）测定分子间界面中所有原子的脱水，（b）加入真空氢键能，和（c）进一步增加相互作用的伙伴在互动时的自由焓的变化。获得的结果可以用于预测各种来源的两个分子如何以及在何种程度上相互适应。

58. 发明申请

US20070162991A1 Transgenic mice containing Lrp5 gene disruptions 审中-公开
标题翻译：含有Lrp5基因破坏的转基因小鼠
公开(公告)号：US20070162991A1
公开(公告)日：2007-07-12
申请号：US11385243
申请日：2006-03-20
申请人： Robert Klein
发明人： Robert Klein
IPC分类号： A01K67/027
CPC分类号： C07K14/705 , A01K67/0275 , A01K2217/072 , A01K2217/075 , A01K2217/20 , A01K2227/105 , A01K2267/03 , A01K2267/0356 , A01K2267/0393 , C12N15/8509 , C12N2800/30
摘要： The present disclosure relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present disclosure provides transgenic mice comprising mutations in a low density lipoprotein-related protein 5 (Lrp5) gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
摘要翻译：本公开涉及转基因动物，以及与基因功能表征相关的组合物和方法。具体地，本公开提供了包含低密度脂蛋白相关蛋白5（Lrp5）基因突变的转基因小鼠。这样的转基因小鼠可用作疾病的模型并用于鉴定调节基因表达和基因功能的试剂，以及作为各种疾病状态和疾病状况的潜在治疗。

59. 发明申请

US20060292114A1 Neurturin receptor 有权
公开(公告)号：US20060292114A1
公开(公告)日：2006-12-28
申请号：US11508791
申请日：2006-08-22
申请人： Robert Klein , Arnon Rosenthal , Mary Hynes
发明人： Robert Klein , Arnon Rosenthal , Mary Hynes
IPC分类号： A61K38/20 , A61K38/19 , A61K38/18 , A61K38/22 , A61K39/395
CPC分类号： C07K14/705 , A01K67/0275 , A61K2039/505 , C07K16/22 , G01N33/6863 , G01N33/6872 , Y10S930/12
摘要： NTNRα, NTNRα extracellular domain (ECD), NTNRα variants, chimeric NTNRα (e.g., NTNRα immunoadhesion), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described, including methods to modulate cell activity and survival by response to NTNRα-ligands, for example NTN, by providing NTNRα to the cell.

60. 发明申请

US20050175672A1 Particulate plant sterol compositions 审中-公开
标题翻译：颗粒植物固醇组合物
公开(公告)号：US20050175672A1
公开(公告)日：2005-08-11
申请号：US10775933
申请日：2004-02-10
申请人： Michael Kluetz , Robert Klein , Stephen Snyder , Melanie Goulson , Vincent Cavallini
发明人： Michael Kluetz , Robert Klein , Stephen Snyder , Melanie Goulson , Vincent Cavallini
IPC分类号： A23L1/30 , A23L1/302 , A23L2/00 , A23L2/02 , A23L2/06 , A61K47/00
CPC分类号： A23L2/02 , A23L2/06 , A23L33/11 , A23L33/15 , A23V2002/00 , A23V2200/326 , A23V2250/2136 , A23V2200/254
摘要： Particulate plant sterol compositions having defined particle size distribution (PSD) characteristics are provided. Processes for preparing the compositions and methods for dispersing the compositions in aqueous media are also provided.
摘要翻译：提供具有确定的粒度分布（PSD）特性的颗粒植物甾醇组合物。还提供了用于制备组合物的方法和将组合物分散在水性介质中的方法。

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