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51. 发明授权

US06369939B1 Illumination device for a microscope including two light sources 失效
标题翻译：用于显微镜的照明装置包括两个光源
公开(公告)号：US06369939B1
公开(公告)日：2002-04-09
申请号：US09555844
申请日：2000-06-05
申请人： Albrecht Weiss , Michael Ganser , Helmut Rühl , Manfred Gilbert
发明人： Albrecht Weiss , Michael Ganser , Helmut Rühl , Manfred Gilbert
IPC分类号： G02B2112
CPC分类号： G02B21/086
摘要： An illumination system (1) for a microscope, in which a first light source (2), a collector lens (3), an aperture diaphragm (4), and a condenser lens ((5) are arranged in the illumination beam path (6), is described. The illumination light is directed through the aperture diaphragm (4) via the condenser lens (5) into the object plane (9). Arranged in the illumination beam path (6) on the optical axis (20) is a second light source (8) that is imaged at infinity by the condenser lens (5).
摘要翻译：一种用于显微镜的照明系统（1），其中第一光源（2），集光透镜（3），孔径光阑（4）和聚光透镜（（5））布置在照明光束路径照明光通过聚光透镜（5）通过孔径光阑（4）引导到物平面（9）中，在光轴（20）上的照明光束路径（6）中排列为由聚光透镜（5）在无限远处成像的第二光源（8）。

52. 发明授权

US5972668A Production of multi-enzyme granules 失效
标题翻译：生产多酶颗粒
公开(公告)号：US5972668A
公开(公告)日：1999-10-26
申请号：US765379
申请日：1997-07-03
申请人： Meine Georg , Karl-Heinz Maurer , Albrecht Weiss , Kathleen Paatz , Ulrich Haas , Monika Boecker
发明人： Meine Georg , Karl-Heinz Maurer , Albrecht Weiss , Kathleen Paatz , Ulrich Haas , Monika Boecker
IPC分类号： C11D3/386 , C12N9/98 , C12N9/96 , C11D7/42 , C11D17/04
CPC分类号： C11D3/38672 , C12N9/98
摘要： A process is presented for producing stable multi-enzyme containing granules. The process involves the steps of mixing a reversible competitive inhibitor with a first enzyme, adding a second incompatible enzyme, adding a carrier, extruding and granulating the resulting mixture and reducing the moisture content if necessary.
摘要翻译： PCT No.PCT / EP95 / 02363 Sec。 371日期1997年7月3日 102（e）日期1997年7月3日PCT Filed 1995年6月19日PCT公布。出版物WO96 / 00773 日期1996年1月11日提出了一种用于生产稳定的多酶含量颗粒的方法。该方法包括将可逆竞争性抑制剂与第一种酶混合，加入第二种不相容性酶，加入载体，挤出和造粒所得混合物并根据需要降低含水量的步骤。

53. 发明授权

US4518697A Acid stable protease from mutants of genus Aspergillus 失效
标题翻译：来自曲霉属突变体的酸稳定蛋白酶
公开(公告)号：US4518697A
公开(公告)日：1985-05-21
申请号：US449415
申请日：1982-12-13
申请人： Friedhelm Bartnik , Joachim Schindler , Albrecht Weiss , Rolf Schmid
发明人： Friedhelm Bartnik , Joachim Schindler , Albrecht Weiss , Rolf Schmid
IPC分类号： C12N9/58 , A23K20/189 , C12N1/20 , C12N9/62 , C12N1/14 , C12R1/685
CPC分类号： C12R1/685 , A23K20/189 , C12N9/62 , Y10S435/917
摘要： Process for the preparation of acid stable protease having a broad activity spectrum in high yields from mutants of the fungus Aspergillus, and the mutants used therein.
摘要翻译：用于制备具有广谱活性谱的酸稳定蛋白酶的方法，其以高产率从真菌曲霉的突变体及其中使用的突变体制备。

54. 发明授权

US4473644A Acid stable protease from mutants of genus Rhizopus 失效
标题翻译：来自根霉突变体的酸稳定蛋白酶
公开(公告)号：US4473644A
公开(公告)日：1984-09-25
申请号：US409122
申请日：1982-08-18
申请人： Joachim Schindler , Friedhelm Bartnik , Rolf Schmid , Albrecht Weiss
发明人： Joachim Schindler , Friedhelm Bartnik , Rolf Schmid , Albrecht Weiss
IPC分类号： A23K20/189 , C12N1/14 , C12N9/58 , C12R1/845 , C12N15/00
CPC分类号： C12R1/845 , A23K20/189 , C12N9/58 , Y10S435/939
摘要： Process for the preparation of acid stable protease having a broad activity spectrum by culturing selected mutants of Rhizopus rhizopodiformis CBS 227.75 under aerobic conditions in a nutrient medium containing assimilable carbon and nitrogen sources, at a pH between 3 and 7 and at a temperature between 25.degree. C. and 50.degree. C., and separating the resulting protease enzyme; the mutants used in the process together with a process for preparation of the mutants.
摘要翻译：通过在有氧条件下培养选定的根霉（Rhizopus rhizopodiformis）CBS 227.75的突变体，在含有可吸收的碳源和氮源的营养培养基中，pH为3〜7，温度为25℃，制备具有广谱活性谱的酸稳定蛋白酶的方法并分离得到的蛋白酶; 在该过程中使用的突变体连同突变体的制备方法。

55. 发明授权

US09354436B2 Microscope illumination method and microscope 有权
标题翻译：显微镜照明方法和显微镜
公开(公告)号：US09354436B2
公开(公告)日：2016-05-31
申请号：US13558548
申请日：2012-07-26
申请人： Albrecht Weiss
发明人： Albrecht Weiss
IPC分类号： G02B21/10 , G02B21/12 , G02B21/16 , G02B21/08
CPC分类号： G02B21/16 , G02B21/088
摘要： The present invention relates to a method for illuminating a sample (10) in a microscope (26), the sample (10) being analysed in transmitted light bright field illumination or in incident light fluorescence illumination, wherein a white light LED (4) is used as the light source for the transmitted light bright field illumination, and a shutter (6) is activated at a location in the illumination beam path of the transmitted light bright field illumination during incident light fluorescence illumination and this shutter (6) is deactivated during transmitted light bright field illumination.
摘要翻译：本发明涉及一种用于在显微镜（26）中照亮样品（10）的方法，所述样品（10）在透射光明场照明或入射光荧光照明中进行分析，其中白光LED（4）为用作透射光明场照明的光源，并且在入射光荧光照明期间在透射光明场照明的照明光束路径中的位置处激活快门（6），并且该快门（6）在透射光明场照明。

56. 发明授权

US09297992B2 Microscope illumination method and microscope 有权
标题翻译：显微镜照明方法和显微镜
公开(公告)号：US09297992B2
公开(公告)日：2016-03-29
申请号：US13559778
申请日：2012-07-27
申请人： Michael Ganser , Albrecht Weiss
发明人： Michael Ganser , Albrecht Weiss
IPC分类号： G02B21/10 , G02B21/12 , G02B21/08 , G02B21/16 , G02B5/22
CPC分类号： G02B21/088 , G02B5/22 , G02B21/125 , G02B21/16
摘要： The invention relates to a microscope illumination method, to a microscope illumination set, comprising a white light LED (4) and a correction filter (6), and to a corresponding microscope system (1) for analyzing a sample (10) alternately or simultaneously in transmitted light bright field illumination and in incident light fluorescence illumination, wherein a white light LED (4) is used for the transmitted light bright field illumination, and a correction filter (6) is activated at a location in the illumination beam path of the transmitted light bright field illumination both during transmitted light bright field illumination and during incident light fluorescence illumination, wherein the correction filter (6) has a spectral transmission profile which has a minimum in the wavelength range of at least one maximum of the spectrum of the white light LED (4).
摘要翻译：本发明涉及一种显微照明方法，涉及一种包括白光LED（4）和校正滤光片（6）的显微照明组件，以及用于交替或同时分析样品（10）的相应显微系统（1）在透射光明场照明和入射光荧光照明中，其中白光LED（4）用于透射光明场照明，校正滤光片（6）在照明光束路径中的位置被激活在透射光明场照明期间和在入射光荧光照明期间的透射光明场照明，其中所述校正滤光片（6）具有光谱透射分布，所述光谱透射分布在白色光谱的至少一个最大值的波长范围内具有最小值灯LED（4）。

57. 发明授权

US08404468B2 Efficient astaxanthin production strains derived from Haematococcus pluvialis 有权
标题翻译：来源于红球藻的高效虾青素生产菌株
公开(公告)号：US08404468B2
公开(公告)日：2013-03-26
申请号：US12601471
申请日：2008-05-14
申请人： Martin Lucia , Irina Obraztsova , Baldomero F. Cordero , Angeles M. Vargas , Albrecht Weiss , Bernhard Gutsche , Wilhelm Johannisbauer , Herminia Rodriguez
发明人： Martin Lucia , Irina Obraztsova , Baldomero F. Cordero , Angeles M. Vargas , Albrecht Weiss , Bernhard Gutsche , Wilhelm Johannisbauer , Herminia Rodriguez
IPC分类号： C12P1/02 , C12N15/01 , C12N1/15
CPC分类号： C12P1/02 , C12N15/79 , C12P23/00
摘要： The present invention pertains to a method for the efficient production of carotenoids. In particular, the present invention is directed to a method for producing carotenoid and carotenoid-containing cells, especially astaxanthin and astaxanthin-containing cells, by generating mutant microorganisms belonging to the photoautotrophic algae of the Class Chlorophyceae and culturing same. The present invention further relates to methods of generating microorganisms producing high yields of carotenoids, in particular astaxanthin, products containing said microorganisms or said carotenoids, and the use of said carotenoids produced by the microorganisms according to the present invention and deposited mutant strains generated from said microorganisms.
摘要翻译：本发明涉及一种有效生产类胡萝卜素的方法。特别地，本发明涉及通过产生属于类绿藻的光自养藻类的突变微生物并进行培养的方法来生产含有类胡萝卜素和类胡萝卜素的细胞，特别是虾青素和含虾青素的细胞。本发明还涉及产生高产量的类胡萝卜素，特别是虾青素，含有所述微生物或所述类胡萝卜素的产品的微生物的生产方法，以及由本发明的微生物产生的所述类胡萝卜素的用途以及由所述微生物产生的沉积的突变菌株微生物。

58. 发明申请

US20130027769A1 Microscope Illumination Method and Microscope 有权
标题翻译：显微镜照明方法和显微镜
公开(公告)号：US20130027769A1
公开(公告)日：2013-01-31
申请号：US13558548
申请日：2012-07-26
申请人： Albrecht Weiss
发明人： Albrecht Weiss
IPC分类号： G02B21/06
CPC分类号： G02B21/16 , G02B21/088
摘要： The present invention relates to a method for illuminating a sample (10) in a microscope (26), the sample (10) being analysed in transmitted light bright field illumination or in incident light fluorescence illumination, wherein a white light LED (4) is used as the light source for the transmitted light bright field illumination, and a shutter (6) is activated at a location in the illumination beam path of the transmitted light bright field illumination during incident light fluorescence illumination and this shutter (6) is deactivated during transmitted light bright field illumination.
摘要翻译：本发明涉及一种用于在显微镜（26）中照亮样品（10）的方法，所述样品（10）在透射光明场照明或入射光荧光照明中进行分析，其中白光LED（4）为用作透射光明场照明的光源，并且在入射光荧光照明期间在透射光明场照明的照明光束路径中的位置处激活快门（6），并且该快门（6）在透射光明场照明。

59. 发明申请

US20100323415A1 Emulsions in Enzymatic Reactions 失效
标题翻译：酶反应中的乳液
公开(公告)号：US20100323415A1
公开(公告)日：2010-12-23
申请号：US12853657
申请日：2010-08-10
申请人： Albrecht Weiss , Michael Mueller , Eric Dubreucq , Guy Moulin
发明人： Albrecht Weiss , Michael Mueller , Eric Dubreucq , Guy Moulin
IPC分类号： C12P7/64 , C12N9/14 , C12N9/10 , C12N9/16 , C12N9/18 , C12N9/20 , C12P1/00
CPC分类号： C12N9/00 , C12N11/02
摘要： A reaction medium for enzyme-catalyzed reactions is provided, comprising an oil-in-water emulsion including water, an emulsifier, an oil phase and at least one interfacially active enzyme, where the emulsion is produced by the phase inversion temperature process and has a droplet size of 50 to 400 nm. A method for the enzyme-catalyzed esterification, transesterification or hydrolysis of fatty acid alkyl esters and/or triglycerides is also provided where the oil-in-water emulsion is used as the reaction medium.
摘要翻译：提供了用于酶催化反应的反应介质，其包括水包油乳液，其包括水，乳化剂，油相和至少一种界面活性酶，其中乳液通过相转化温度过程产生并具有液滴尺寸为50〜400nm。还提供了一种用于脂肪酸烷基酯和/或甘油三酯的酶催化的酯化，酯交换或水解的方法，其中使用水包油乳液作为反应介质。

60. 发明申请

US20100009063A1 Process for the preparation of active substance concentrate 有权
标题翻译：活性物质浓缩物的制备方法
公开(公告)号：US20100009063A1
公开(公告)日：2010-01-14
申请号：US12271543
申请日：2008-11-14
申请人： Carsten Beverungen , Albrecht Weiss , Eike Ulf Mahnke , Bernhard Gutsche
发明人： Carsten Beverungen , Albrecht Weiss , Eike Ulf Mahnke , Bernhard Gutsche
IPC分类号： A23L1/48
CPC分类号： A61K8/97 , A23F5/267 , A23L33/105 , A61K8/06 , A61K36/16 , A61K36/185 , A61K36/23 , A61K36/27 , A61K36/28 , A61K36/31 , A61K36/45 , A61K36/48 , A61K36/484 , A61K36/49 , A61K36/53 , A61K36/63 , A61K36/76 , A61K36/77 , A61K36/82 , A61K36/84 , A61K36/87
摘要： Disclosed is a process for the preparation of active substance concentrates, which is distinguished in that an active-substance-containing starting material, (i) (a) is either brought into contact with a PIT emulsion and the mixtures are heated to a temperature above the phase inversion temperature of the PIT emulsion, where they are held for a sufficient period of time, or (b) is brought into contact with an aqueous mixture of lipids and emulsifiers, which mixture is suitable for the formation of PIT emulsions, and the mixture is heated with strong shearing to a temperature above the phase inversion temperature with in-situ formation of a PIT emulsion, where the mixture is held for a sufficient period of time, (ii) the mixtures are cooled and filtered and, if appropriate, (iii) subjected to ultrafiltration and/or (iv) a further solvent extraction.
摘要翻译：公开了一种制备活性物质浓缩物的方法，其特征在于含有活性物质的原料（i）（a）与PIT乳液接触，将混合物加热至高于将PIT乳液的相转化温度保持足够的时间，或（b）与脂质和乳化剂的水性混合物接触，该混合物适于形成PIT乳液，并且将混合物用强剪切加热至高于相转化温度的温度，其中原位形成PIT乳液，其中混合物保持足够的时间，（ii）将混合物冷却并过滤，如果合适，（iii）进行超滤和/或（iv）进一步的溶剂萃取。

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