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51. 发明申请

US20050025702A1 MATRIX METALLOPROTEINASE INHIBITORS 失效
标题翻译：基质金属蛋白酶抑制剂
公开(公告)号：US20050025702A1
公开(公告)日：2005-02-03
申请号：US09783248
申请日：2001-02-14
申请人： Carl Decicco , David Nelson , John Barrett , Alan Carpenter , Jingwu Duan , Milind Rajopadhye
发明人： Carl Decicco , David Nelson , John Barrett , Alan Carpenter , Jingwu Duan , Milind Rajopadhye
IPC分类号： A61K49/00 , A61K49/14 , A61K51/08 , C07D207/26 , C07D213/82 , C07D267/00 , C07D401/12 , C07D401/14 , C07D413/12 , C07F9/6527 , A61K51/00
CPC分类号： A61K49/14 , A61K49/0002 , A61K49/085 , A61K49/10 , A61K51/088 , C07D207/26 , C07D213/82 , C07D267/00 , C07D401/12 , C07D401/14 , C07D413/12 , C07F9/6527
摘要： Thus the present invention describes novel compounds comprising: 1-10 targeting moieties; a chelator (Ch); and 0-1 linking groups (Ln) between the targeting moiety and chelator; wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to a cytotoxic radioisotope. The present invention also provides novel compositions of the compounds of the invention, kits, and their uses in treatment of diseases associated with MMPs.
摘要翻译：因此，本发明描述了新的化合物，其包含：1-10个靶向部分; 螯合剂（Ch）; 和靶向部分和螯合剂之间的0-1个连接基团（Ln）; 其中靶向部分是基质金属蛋白酶抑制剂; 并且其中所述螯合剂能够缀合到细胞毒性放射性同位素。本发明还提供本发明化合物，试剂盒及其用于治疗与MMP相关的疾病的新型组合物。

52. 外观设计

USD497509S1 Straw with angled output 失效
标题翻译：秸秆角度输出
公开(公告)号：USD497509S1
公开(公告)日：2004-10-26
申请号：US29196018
申请日：2003-12-20
申请人： David Nelson
设计人： David Nelson

53. 发明授权

US06185862B1 Capturing device for insects 失效
标题翻译：昆虫捕获装置
公开(公告)号：US06185862B1
公开(公告)日：2001-02-13
申请号：US09246543
申请日：1999-02-08
申请人： David Nelson
发明人： David Nelson
IPC分类号： A01M302
CPC分类号： A01M1/14 , A01M3/04 , A01M2200/011 , A01M2200/012
摘要： A device for manually capturing and restraining intended insects, the same comprising a pad of stacked, singular sheets each sheet having a partial enveloping means comprised of hydrophillic absorbing material and collapsible sheet construction whereby the sheet partially conforms in response to the insects body mass. Each sheet has a region is coated with a mild compression adhesive material capable of trapping of an insect in response to the physical manipulation by a human being. The pad of stacked adhesive sheets can be used by separating each sheet individually or as a stack. Upon apprehension of an insect, the sheet restraining the insect is separated, if not already separated from its stack, folded to encase the insect and ready for disposal. The pad of stacked adhesive sheets can have various sheet sizes, thickness and density with varying enveloping ability—all depending upon intended insect to be trapped. For increasing the maneuverability of the device, the device can be attached to an elongated rod such as a fly swatter's handle.
摘要翻译：用于手动捕获和限制预期昆虫的装置，其包括层叠的单张片的垫片，每片具有由亲水吸收材料和可折叠片材构造组成的部分包封装置，由此片材响应于昆虫体重部分地符合。每个片材具有涂覆有能够响应于人的物理操纵而捕获昆虫的温和压缩粘合剂材料的区域。堆叠的粘合片的垫片可以通过单独地或作为叠层分离每个片材来使用。在逮捕昆虫时，如果没有将昆虫分离出来，那么将昆虫的片材分开，折叠起来包住昆虫并准备处置。堆叠粘合片的垫片可以具有各种片材尺寸，厚度和密度，具有变化的包封能力，全部取决于要捕获的预期昆虫。为了增加装置的可操作性，该装置可以附接到细长的杆，例如飞溅物的把手。

54. 发明授权

US10553129B2 System and method for recording, documenting and visualizing group conversations 有权
公开(公告)号：US10553129B2
公开(公告)日：2020-02-04
申请号：US15658511
申请日：2017-07-25
申请人： David Nelson
发明人： David Nelson
IPC分类号： G09B19/00 , G06F3/0481 , G06F3/16 , G06F3/0482 , G09B5/06 , G06T11/20 , G10L21/0272 , G10L25/87
摘要： The present disclosure provides systems and methods for recording, documenting, and visualizing group conversations. More specifically, the present invention relates to systems and methods that allows users to record conversations, document each speaker, visualize the conversation in real time, play back the conversation with visualization for how the conversation progressed from person to person, and compile result statistics on participation levels.

55. 发明申请

US20180036161A1 JOINT STABILIZING ORTHOPEDIC DEVICE 审中-公开
公开(公告)号：US20180036161A1
公开(公告)日：2018-02-08
申请号：US15668579
申请日：2017-08-03
申请人： Christian A. Alvarez , Robert B. Murray, III , David Nelson , John Lucas
发明人： Christian A. Alvarez , Robert B. Murray, III , David Nelson , John Lucas
IPC分类号： A61F5/01 , A63B21/04
CPC分类号： A61F5/0118 , A63B21/00061 , A63B21/00065 , A63B21/0442 , A63B21/0552 , A63B21/4005 , A63B21/4007 , A63B21/4017 , A63B21/4025 , A63B23/0494 , A63B23/1245 , A63B2225/09
摘要： The disclosure described herein is directed to an orthopedic device configured to provide support and/or resistance to a joint. The orthopedic device is adjustable and lightweight and configured to permit a substantial full range of motion of the joint. The orthopedic device can comprise a torso portion, an upper arm portion, and a support system, wherein at least the support system is adapted to mimic part of the muscular system structure and function of the muscles that are used during the range of motion of the joint.

56. 发明申请

US20180033332A1 System and Method for Recording, Documenting and Visualizing Group Conversations 审中-公开
公开(公告)号：US20180033332A1
公开(公告)日：2018-02-01
申请号：US15658511
申请日：2017-07-25
申请人： David Nelson
发明人： David Nelson
IPC分类号： G09B19/00 , G06F3/0481 , G10L25/87 , G09B5/06 , G06T11/20 , G10L21/0272 , G06F3/0482 , G06F3/16
CPC分类号： G09B19/00 , G06F3/04817 , G06F3/0482 , G06F3/165 , G06Q10/107 , G06Q50/01 , G06T11/206 , G09B5/06 , G09B5/065 , G10L21/0272 , G10L25/87 , H04L12/1831 , H04M3/42221 , H04M3/56 , H04M2201/42
摘要： The present disclosure provides systems and methods for recording, documenting, and visualizing group conversations. More specifically, the present invention relates to systems and methods that allows users to record conversations, document each speaker, visualize the conversation in real time, play back the conversation with visualization for how the conversation progressed from person to person, and compile result statistics on participation levels.

57. 发明授权

US09579832B2 Method of shortening the time to compression mold a roofing shingle or tile and apparatus for facilitating same 有权
标题翻译：缩短压缩模具屋顶瓦房或瓷砖的时间的方法和便于其使用的装置
公开(公告)号：US09579832B2
公开(公告)日：2017-02-28
申请号：US13652720
申请日：2012-10-16
申请人： Thomas Kevin MacKinnon , David Nelson , Nolan Loy Son , Trevor Reeve
发明人： Thomas Kevin MacKinnon , David Nelson , Nolan Loy Son , Trevor Reeve
IPC分类号： B29C43/04 , B29C43/18 , B29C43/34 , B29C43/00 , B29K703/08 , B29L31/10
CPC分类号： B29C43/18 , B29C43/00 , B29C43/34 , B29C2043/3416 , B29C2043/3433 , B29K2703/08 , B29L2031/104 , Y10T442/3878
摘要： A method of shortening cycle time required to compression mold shingle or tile is provided, wherein carrier plates are comprised of a surface material and a base, and receive a thermoplastic material, thereon. The roofing material is applied to the carrier plate and the carrier plate is subjected to induction heating, by which its surface material has its temperature raised, without substantially raising the temperature of the carrier plate base, such that the thermoplastic material applied thereto is kept heated in the compression mold. Cooling of the thermoplastic material is by heat transfer from the carrier plate surface material to the carrier plate base, and with both materials having good heat conduction capability. The carrier plate surface material has a high receptivity to being heated by induction heating relative the carrier plate base. The carrier plates are serially delivered through the process, to the compression mold.
摘要翻译：提供了一种缩短压缩模板或瓦片所需的循环时间的方法，其中承载板由表面材料和基底构成，并且在其上容纳热塑性材料。将屋顶材料施加到承载板上，并且承载板经受感应加热，通过该感应加热，其表面材料具有其升高的温度，而基本上不升高承载板基座的温度，使得施加到其上的热塑性材料保持加热在压缩模具中。热塑性材料的冷却是通过从承载板表面材料到承载板基底的热传递，并且两种材料具有良好的导热能力。承载板表面材料通过感应加热相对于承载板底座具有高的接受性。承载板通过该过程被顺序地输送到压缩模具。

58. 发明申请

US20150359172A1 Rotary Trimmer with Cutting Blade and Line and Blades for Use with Same 审中-公开
标题翻译：带切割刀片的旋切机和与其一起使用的线和刀片
公开(公告)号：US20150359172A1
公开(公告)日：2015-12-17
申请号：US14717991
申请日：2015-05-20
申请人： David Nelson
发明人： David Nelson
IPC分类号： A01D34/73 , A01D34/416
CPC分类号： A01D34/733 , A01D34/416 , A01D34/73
摘要： A rotary tool for cutting woody brush, that includes an engine, a transmission for transferring rotational movement to a head, an elongate pole, and the head is positioned at the end of the pole, and connected to the head is a cutting blade that has a flat middle section that is adapted to engage and opposite cutting sections that extend downwardly from the middle section, and the cutting sections have cutting surfaces and, in embodiments, the tool includes cutting line.
摘要翻译：一种用于切割木质刷子的旋转工具，其包括发动机，用于将旋转运动传递到头部的传动装置，细长杆体和头部位于杆的端部，并且连接到头部是具有平坦的中间部分适于接合和相对的从中间部分向下延伸的切割部分，并且切割部分具有切割表面，并且在实施例中，该工具包括切割线。

59. 外观设计

USD743448S1 Cutting blade for rotary tool 有权
标题翻译：旋转刀具切割刀片
公开(公告)号：USD743448S1
公开(公告)日：2015-11-17
申请号：US29490645
申请日：2014-05-12
申请人： David Nelson
设计人： David Nelson

60. 发明授权

US08647202B2 Companion object customization 有权
标题翻译：伴随对象定制
公开(公告)号：US08647202B2
公开(公告)日：2014-02-11
申请号：US12970674
申请日：2010-12-16
申请人： Sari Crevin , John Ikeda , David Nelson , Brian Allen Bilodeau
发明人： Sari Crevin , John Ikeda , David Nelson , Brian Allen Bilodeau
IPC分类号： A63F9/24 , A63F13/00 , G06F17/00 , G06F19/00
CPC分类号： A63F13/04 , A63F13/213 , A63F13/28 , A63F13/67 , A63F13/825 , A63F13/98 , A63H3/28 , A63H2200/00
摘要： A game-interactive customizable companion object includes a body, a communication subsystem housed within the body, and a behavior subsystem configured to control movement of the body. The behavior subsystem may include an initiation module configured to set initial behavioral characteristics of the companion object in accordance with the companion object profile, and an update module configured to change behavioral characteristics of the companion object responsive to control commands received from the entertainment system via the communication subsystem.
摘要翻译：游戏交互式可定制的伴侣对象包括身体，容纳在身体内的通信子系统，以及被配置为控制身体移动的行为子系统。行为子系统可以包括启动模块，其被配置为根据伴随对象简档来设置伴随对象的初始行为特征，以及更新模块，被配置为响应于从娱乐系统接收到的控制命令，改变伴随对象的行为特征通讯子系统。

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