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    • 58. 发明申请
    • Process method to facilitate silicidation
    • 硅化方法
    • US20060014393A1
    • 2006-01-19
    • US10894374
    • 2004-07-19
    • Jiong-Ping LuFreidoon MehradLindsey HallVivian LiuClint MontgomeryScott Johnson
    • Jiong-Ping LuFreidoon MehradLindsey HallVivian LiuClint MontgomeryScott Johnson
    • H01L21/302
    • H01L21/28518H01L21/02046H01L21/0206H01L21/28052H01L29/665
    • The present invention substantially removes dry etch residue from a dry plasma etch process 110 prior to depositing a cobalt layer 124 on silicon substrate and/or polysilicon material. Subsequently, one or more annealing processes 128 are performed that cause the cobalt to react with the silicon thereby forming cobalt silicide regions. The lack of dry etch residue remaining between the deposited cobalt and the underlying silicon permits the cobalt silicide regions to be formed substantially uniform with a desired silicide sheet and contact resistance. The dry etch residue is substantially removed by performing a first cleaning operation 112 and then an extended cleaning operation 114 that includes a suitable cleaning solution. The first cleaning operation typically removes some, but not all of the dry etch residue. The extended cleaning operation 114 is performed at a higher temperature and/or for an extended duration and substantially removes dry etch residue remaining after the first cleaning operation 112.
    • 本发明在将钴层124沉积在硅衬底和/或多晶硅材料上之前基本上从干等离子体蚀刻工艺110去除干蚀刻残留物。 随后,进行一个或多个退火工艺128,其使钴与硅反应,从而形成硅化钴区域。 残留在沉积的钴和下面的硅之间的干蚀刻残留物的缺乏允许用期望的硅化物片和接触电阻基本上均匀地形成硅化钴区域。 通过执行第一清洁操作112,然后进行包括合适的清洁溶液的延长清洁操作114,基本上去除了干蚀刻残留物。 第一次清洁操作通常去除一些但不是全部的干蚀刻残留物。 延长的清洁操作114在更高的温度和/或延长的持续时间内进行,并且基本上去除了在第一清洁操作112之后残留的干蚀刻残留物。
    • 59. 发明申请
    • Multiple antigenic peptides immunogenic against Streptococcus pneumonia
    • 针对肺炎链球菌免疫原性的多种抗原肽
    • US20050226891A1
    • 2005-10-13
    • US11145814
    • 2005-06-06
    • Edwin AdesScott JohnsonDanny JueJacquelyn SampsonGeorge Carlone
    • Edwin AdesScott JohnsonDanny JueJacquelyn SampsonGeorge Carlone
    • A61K38/00A61K39/00C07K7/08C07K14/315G01N33/554A61K39/02G01N33/569
    • C07K7/08A61K38/00A61K39/00C07K14/3156Y10S530/806Y10S530/825
    • The invention provides a nucleic acid encoding the 37-kDa pneumococcal surface adhesion A protein (PsaA) from Streptococcus pneumoniae. Also provided are isolated nucleic acids comprising a unique fragment of at least 10 nucleotides of the 37-kDa protein. The invention also provides purified polypeptides encoded by the nucleic acid encoding the 37-kDa protein from and the nucleic acids comprising unique fragment of at least 10 nucleotides of the 37-kDa protein. The invention further provides monoclonal antibodies which selectively bind PsaA. In addition, peptides are provided that immunospecifically bind to the monoclonal antibodies of the invention, and that are immunogenic against Streptococcus pneumoniae infection. Additionally, multiple antigenic peptides that provide protection against S. pneumoniae challenge are provided. These multiple antigen peptides comprise the peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering therapeutic composition comprising the immunogenic peptides of the invention. Also provided are methods of detecting the presence of Streptococcus pneumoniae in a sample using antibodies or antigens and methods of preventing and treating Streptococcus pneumoniae infection in a subject. In addition, a method of identifying the sequence of a peptide potentially capable of eliciting protective immunity against a pathogenic microorganism is provided.
    • 本发明提供编码来自肺炎链球菌的37-kDa肺炎球菌表面粘附A蛋白(PsaA)的核酸。 还提供了分离的核酸,其包含37-kDa蛋白质的至少10个核苷酸的独特片段。 本发明还提供由编码37-kDa蛋白质的核酸编码的纯化多肽和包含37-kDa蛋白质至少10个核苷酸的独特片段的核酸。 本发明还提供选择性结合PsaA的单克隆抗体。 此外,提供了免疫特异性结合本发明的单克隆抗体并且对肺炎链球菌感染具有免疫原性的肽。 另外,提供了提供针对肺炎链球菌攻击的保护的多种抗原肽。 这些多重抗原肽包含免疫特异性结合单克隆抗体的肽。 还提供了包含这种免疫原性肽的疫苗,以及通过施用包含本发明的免疫原性肽的治疗组合物来赋予对肺炎链球菌感染的保护性免疫的方法。 还提供了使用抗体或抗原检测样品中肺炎链球菌存在的方法以及在受试者中预防和治疗肺炎链球菌感染的方法。 此外,提供了鉴定潜在地能够引发对病原微生物的保护性免疫的肽的序列的方法。
    • 60. 发明申请
    • Network abstraction and isolation layer rules-based federation and masquerading
    • 网络抽象和隔离层基于规则的联合和伪装
    • US20050147120A1
    • 2005-07-07
    • US11053770
    • 2005-02-09
    • Charles WillmanScott JohnsonDave McCroryRobert Hirschfeld
    • Charles WillmanScott JohnsonDave McCroryRobert Hirschfeld
    • H04J3/16H04J3/22H04L12/28H04L12/56
    • H04L61/2514H04L61/2521
    • A computer system of a federation coupled to a network including a server having an internal address associated with a first subnet and a network abstraction and isolation layer rules-based federation and masquerading (NAIL RBFM) interface that interfaces the server with the network. The NAIL RBFM interface transforms the internal address between the first subnet and a second subnet for intra-federation communications. The NAIL RBFM interface performs transform and inverse transform operations to convert between internal and external addresses of intra-federation network traffic. The operations may be performed on source and destination addresses, and may be configured in any of several manners, such as modifying at least one bit of an address, replacing at least one octet of an IP address, substituting a prefix of an address, replacing an entire address, etc.
    • 耦合到包括具有与第一子网相关联的内部地址的服务器的网络的联盟的计算机系统以及将服务器与网络接口的网络抽象和隔离层规则的联合和伪装(NAIL RBFM)接口。 NAIL RBFM接口转换第一个子网和第二个子网之间的内部地址以进行联合通信。 NAIL RBFM接口执行变换和逆变换操作,以在联合网络流量的内部和外部地址之间进行转换。 操作可以在源地址和目的地址上执行,并且可以以以下几种方式中的任何一种来配置,诸如修改地址的至少一个位,替换IP地址的至少一个八位字节,替换地址的前缀,替换 整个地址等