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51. 发明申请

US20070020704A1 Diaryl ureas with kinase inhibiting activity 审中-公开
标题翻译：具有激酶抑制活性的二芳基脲
公开(公告)号：US20070020704A1
公开(公告)日：2007-01-25
申请号：US10571100
申请日：2004-05-19
申请人： Scott Wilhelm , Jacques Dumas , Gaetan Ladouceur , Mark Lynch , William Scott
发明人： Scott Wilhelm , Jacques Dumas , Gaetan Ladouceur , Mark Lynch , William Scott
IPC分类号： G01N33/567 , C12Q1/37 , A61K31/165 , A61K31/16 , A61K31/66
CPC分类号： A61K45/06 , A61K31/00 , A61K31/16 , A61K31/165 , A61K31/4412 , A61K31/4418 , A61K31/443 , A61K31/66 , A61L31/16 , A61L2300/204 , A61L2300/416 , G01N33/5041 , G01N33/5743 , G01N33/57438 , A61K2300/00
摘要： The present invention provides methods of using aryl ureas to treat diseases and conditions associated with signal transduction pathways comprising at least one of raf, VEGFR, PDGFR, p38 and/or FLT-3. The present invention also provides compositions and methods for identifying conditions and diseases which can be modulated with compounds of the present invention. These methods facilitate the selection of subjects who can be efficiently treated with compounds of the present invention. Additionally, the invention provides methods for monitoring subjects who have been administered a compound of the present invention.
摘要翻译：本发明提供使用芳基脲来治疗与包含raf，VEGFR，PDGFR，p38和/或FLT-3中的至少一种的信号转导途径相关的疾病和病症的方法。本发明还提供用于鉴定可用本发明化合物调节的病症和疾病的组合物和方法。这些方法有助于选择可以用本发明化合物有效治疗的受试者。此外，本发明提供了用于监测已经施用本发明化合物的受试者的方法。

52. 发明申请

US20060277816A1 Conical point sharpener 失效
标题翻译：圆锥磨刀机
公开(公告)号：US20060277816A1
公开(公告)日：2006-12-14
申请号：US11442466
申请日：2006-05-25
申请人： William Scott
发明人： William Scott
IPC分类号： A01K83/00
CPC分类号： A01K97/00 , B24B19/16 , B24D15/06
摘要： A conical point sharpener for sharpening conical shaped points such as fishhooks, needles, surgical instruments includes a handle, a mandril with an abrasive material coating fixed to one end of said handle, a drive spindle, wherein said drive spindle is movably attached to said handle and envelops said mandril, an outwardly protruding tapered opening on said drive spindle, and a precision point alignment nest, formed between said abrasive material coating on said mandril and said drive spindle, such that when the conical point to be sharpened is placed in said outwardly protruding tapered opening of said drive spindle, the item to be sharpened is located in said precision point alignment nest and the point of the item is touching said abrasive material coating on said mandril so that the user can then rotate said drive spindle while holding the item to be sharpened, thereby conically sharpening the point as the item to be sharpened rotates around said mandril.
摘要翻译：一种锥形点磨刀器，用于磨削圆锥形点，例如鱼钩，针，外科器械，包括手柄，固定到所述手柄的一端的磨料涂层的心轴，驱动心轴，其中所述驱动心轴可移动地连接到所述手柄并且在所述驱动主轴上包围所述的中心锥体，一个向外突出的锥形开口，以及形成在所述心轴上的所述研磨材料涂层和所述驱动心轴之间的精密点对准座，使得当要被削尖的锥形点被放置在所述向外所述驱动轴的突出的锥形开口，待磨削的物品位于所述精密点对准座中，并且物品的点接触所述心轴上的所述磨料涂层，使得使用者可以在保持物品的同时旋转所述驱动主轴被削尖，从而当要削尖的物品围绕所述心轴旋转时锥形磨锐。

53. 发明申请

US20050081175A1 Method for discrete gate sizing in a netlist 审中-公开
标题翻译：网表中离散门尺寸的方法
公开(公告)号：US20050081175A1
公开(公告)日：2005-04-14
申请号：US10683628
申请日：2003-10-10
申请人： William Scott , Viktor Lapinskii
发明人： William Scott , Viktor Lapinskii
IPC分类号： G06F9/45 , G06F17/50
CPC分类号： G06F17/505
摘要： A set of gate sizes for a netlist having a plurality of gates wherein for each of the gates a number of discrete gate sizes is available is selected such that the selection minimizes worst slack in the netlist. A current gate size for each gate is selected and an a current weight assigned to each one of the timing edges in the netlist. A new gate size is selected for each one of the gates from one of the current gate size and second one of the available gates sizes wherein such selection of each new gate size minimizes a sum of weighted delays obtained over all timing edges. The minimum sum of weighted delays is obtained from a min-cut in a timing flow graph. The results of the min-cut are used in the next iteration and re-iterating occurs until an exit criteria is determined.
摘要翻译：具有多个门的网表的一组门尺寸，其中对于每个门，选择多个离散门尺寸是可用的，使得选择使网表中最差的松弛最小化。选择每个门的当前门尺寸和分配给网表中的每个时序边缘的当前权重。从当前栅极尺寸和可用栅极尺寸中的一个选择栅极大小，其中每个新栅极尺寸的这种选择使得在所有定时边缘上获得的加权延迟之和最小化。加权延迟的最小总和是从定时流程图中的最小值获得的。最小切割的结果在下一次迭代中使用，并且重新迭代发生，直到确定退出标准。

54. 发明授权

US06799694B1 Speciman cup with handle 失效
标题翻译：标准杯带手柄
公开(公告)号：US06799694B1
公开(公告)日：2004-10-05
申请号：US10455966
申请日：2003-06-06
申请人： William Scott
发明人： William Scott
IPC分类号： B65D2528
CPC分类号： A61B10/007
摘要： A speciman cup with handle for improving sanitary performance and ease of use of providing a specimen. The speciman cup with handle includes a container member having a bottom wall and a perimeter wall extending upwardly from said bottom wall, the container member defines an interior space, and a lid member couplable to the container member for selectively closing the container.
摘要翻译：具有手柄的标准杯，用于提高卫生性能并提供样品的易用性。具有手柄的标准杯包括具有底壁和从所述底壁向上延伸的周壁的容器构件，容器构件限定内部空间，以及可与容器构件联接的盖构件，用于选择性地关闭容器。

55. 发明授权

US06344476B1 Inhibition of p38 kinase activity by aryl ureas 失效
公开(公告)号：US06344476B1
公开(公告)日：2002-02-05
申请号：US09083396
申请日：1998-05-22
申请人： Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
发明人： Gerald Ranges , William Scott , Michael Bombara , Deborah Rauner , Aniko Redman , Roger Smith , Holger Paulsen , David Gunn , Jinshan Chen , Joel Renick
IPC分类号： A61K3138
CPC分类号： A61K31/4709 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/4025 , A61K31/433 , Y02A50/411 , Y02A50/414
摘要： This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical compositions for use in such therapy.

56. 发明授权

US5689092A Conveyor friction scale 失效
标题翻译：输送机摩擦秤
公开(公告)号：US5689092A
公开(公告)日：1997-11-18
申请号：US662683
申请日：1996-06-12
申请人： Albert Wurz , William Scott , Richard Skokowski
发明人： Albert Wurz , William Scott , Richard Skokowski
IPC分类号： B65B35/44 , G01G11/00 , G01G11/04 , G01G19/03 , G01L5/00 , G01G19/00 , G01G13/02 , G01G19/22 , G01N3/56
CPC分类号： G01G11/046 , G01G11/006 , G01G19/03
摘要： A conveyor scale assembly for use in combination with a conveyor belt for weighing an article on the moving conveyor belt. The conveyor scale assembly is comprised of a slider bed which contacts the underside of the moving conveyor belt which generates a friction force between the conveyor belt and the slider bed. Attached to the slider bed is a sensor which continuously measures the friction force and transmits data representing the measured friction force. A CPU receives and processes the representative data and provides a weight for the article on the conveyor belt.
摘要翻译：一种用于与传送带组合使用的输送机秤组件，用于称重移动的传送带上的物品。输送机秤组件包括滑动床，滑动床接触移动的传送带的下侧，其在传送带和滑动床之间产生摩擦力。连接到滑块床的是传感器，其连续测量摩擦力并发送表示测量摩擦力的数据。 CPU接收并处理代表性数据，并为传送带上的物品提供重量。

57. 发明授权

US5548107A Scanner for reconstructing optical codes from a plurality of code fragments 失效
标题翻译：用于从多个代码片段重建光学代码的扫描器
公开(公告)号：US5548107A
公开(公告)日：1996-08-20
申请号：US087597
申请日：1993-07-02
申请人： Charles Lapinski , Charles Eckert , Richard Skokowski , James Cox , William Scott , Edward Chaleff , Meghanad D. Wagh
发明人： Charles Lapinski , Charles Eckert , Richard Skokowski , James Cox , William Scott , Edward Chaleff , Meghanad D. Wagh
IPC分类号： G06K7/016 , G06K7/10 , G06K7/14
CPC分类号： G06K7/0166 , G06K7/10871 , G06K7/14 , G06K7/1491
摘要： A scanner which can read machine-readable code on an object. A scanner has a scanning device, a data device and a reconstruction device. The scanning device can repetively scan the code and provide a scan signal repetively corresponding to at least fragments of the code. The data device is coupled to the scanning device and responds to its scan signal for repetively storing it. The reconstruction device is coupled to the data device for reconstructing the code from at least two of the fragments of the code.
摘要翻译：可以读取对象上的机器可读代码的扫描仪。扫描仪具有扫描装置，数据装置和重建装置。扫描装置可以重复地扫描代码并提供重复地对应于代码片段的扫描信号。数据设备耦合到扫描设备并响应其扫描信号以重复存储它。重建设备耦合到数据设备，用于从代码的至少两个片段重建代码。

58. 发明授权

US5466921A Scanner to combine partial fragments of a complete code 失效
标题翻译：扫描器组合完整代码的部分片段
公开(公告)号：US5466921A
公开(公告)日：1995-11-14
申请号：US902574
申请日：1992-06-22
申请人： Charles Lapinski , Charles Eckert , Richard Skokowski , James Cox , William Scott , Edward Chaleff , Jeffrey G. Sharpe , David A. Wurz
发明人： Charles Lapinski , Charles Eckert , Richard Skokowski , James Cox , William Scott , Edward Chaleff , Jeffrey G. Sharpe , David A. Wurz
IPC分类号： G06K7/10 , G06K7/016 , G06K7/14
CPC分类号： G06K7/10871 , G06K7/0166 , G06K7/14 , G06K7/1491
摘要： A scanner can read machine-readable code on an object. A scanner has a scanning device, a data device, and a registration device. The scanning device can repetitively scan the code and provide a scan signal repetitively corresponding to at least fragments of the code. The data device is coupled to the scanning device and responds to its scan signal for repetitively storing it. The registration device is coupled to the data device for reconstructing the code from at least two of the fragments of the code by relatively shifting the code fragments until they are in registration.

59. 发明授权

US09468642B2 Imidazopyrazines 有权
标题翻译：咪唑吡嗪
公开(公告)号：US09468642B2
公开(公告)日：2016-10-18
申请号：US13635734
申请日：2011-03-16
申请人： Ulrich Klar , Marcus Koppitz , Dirk Kosemund , Rolf Bohlmann , Benjamin Bader , Philip Lienau , Gerhard Siemeister , Stefan Prechtl , Duy Nguyen , William Scott
发明人： Ulrich Klar , Marcus Koppitz , Dirk Kosemund , Rolf Bohlmann , Benjamin Bader , Philip Lienau , Gerhard Siemeister , Stefan Prechtl , Duy Nguyen , William Scott
IPC分类号： C07D487/14 , A61K31/519 , C07D487/04 , A61K45/06
CPC分类号： A61K31/519 , A61K45/06 , C07D487/04 , C07D487/14
摘要： The present invention relates to imidazopyrazine compounds of general Formula (I): in which X, R1, R2, R3a, R3b, R4a, R4b, R4C, and R4D are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, as well as to intermediate compounds useful in the preparation of said compounds.

60. 发明授权

US09326908B2 Body stretching assembly 有权
标题翻译：身体拉伸组装
公开(公告)号：US09326908B2
公开(公告)日：2016-05-03
申请号：US14161257
申请日：2014-01-22
申请人： William Scott
发明人： William Scott
IPC分类号： A61H1/02 , A63B21/00 , A63B21/16 , A63B21/068
CPC分类号： A61H1/02 , A61H1/0237 , A61H1/0274 , A61H1/0296 , A61H2201/1261 , A61H2201/1269 , A61H2201/1607 , A61H2201/1638 , A61H2201/1642 , A61H2201/1664 , A63B21/00178 , A63B21/00185 , A63B21/068 , A63B21/154 , A63B21/1663 , A63B21/4003 , A63B21/4019 , A63B21/4035
摘要： A body stretching assembly is provided. The assembly comprises a pulley, a plurality of body attachment straps, and a rope. The pulley comprises a securing end and a wheeled end, wherein the securing end includes a frame having a proximal aperture, a protrusion, and a pair of distal legs with fastening apertures. The proximal aperture is configured for connection with a pulley assembly supporting structure, such as a door jam or an exposed support such as a pole. A user threads a rope over the pulley wheel to begin treatment. One end of the rope comprises a hand attachment, whereas the opposing rope end includes one of a head, hand, or ankle attachment. The user pulls one end of the rope, thereby causing the opposing end to pull on the body of a user. Gradual actuation of the rope end provides a stretching exercise to a user.
摘要翻译：提供身体拉伸组件。组件包括滑轮，多个主体附接带和绳索。所述滑轮包括固定端和轮端，其中所述固定端包括具有近端孔，突起和具有紧固孔的一对远端腿的框架。近端孔被构造成用于与滑轮组件支撑结构（例如门堵塞或暴露的支撑件例如杆）连接。用户将绳索穿过皮带轮轮开始治疗。绳索的一端包括手部附件，而相对的绳索端部包括头部，手部或脚踝附件中的一个。使用者拉动绳索的一端，从而使相对端拉动使用者的身体。绳索端部的逐渐致动为使用者提供伸展运动。

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