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51. 发明申请

US20090247572A1 AGENT FOR TREATING ATRIAL FIBRILLATION 审中-公开
标题翻译：用于治疗ATRIAL FIBRILLATION的代理
公开(公告)号：US20090247572A1
公开(公告)日：2009-10-01
申请号：US12064148
申请日：2006-08-22
申请人： Koichi Wada , Noriyuki Masuda , Keiichi Taniguchi
发明人： Koichi Wada , Noriyuki Masuda , Keiichi Taniguchi
IPC分类号： A61K31/4725 , A61P9/00
CPC分类号： C07D401/06 , A61K31/4725
摘要： It is intended to provide an agent for treating atrial fibrillation, comprising an If current inhibitor as an active ingredient. In the present invention, the means for resolution comprises an agent for treating atrial fibrillation, comprising an If current inhibitor as an active ingredient. In particular, it comprises an agent for treating atrial fibrillation comprising (−)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide monophosphate as an active ingredient. The active ingredient according to the present invention has more preferred properties for use as an agent for treating atrial fibrillation compared to Verapamil (a Ca antagonist) and Atenolol (a β-blocker) which have been conventionally used as the agents for treating atrial fibrillation.
摘要翻译：本发明提供一种治疗心房颤动的药剂，其包含If电流抑制剂作为活性成分。在本发明中，解决方法包括用于治疗心房颤动的药剂，其包含If电流抑制剂作为活性成分。特别地，其包含用于治疗房颤的药剂，其包含（ - ） - N- {2 - [（R）-3-（6,7-二甲氧基-1,2,3,4-四氢异喹啉-2-羰基）哌啶子基 ]乙基} -4-氟苯甲酰胺单磷酸酯作为活性成分。与通常用作治疗心房颤动的药物的维拉帕米（Ca拮抗剂）和阿替洛尔（β-阻断剂）相比，本发明的活性成分具有更优选的用作治疗心房颤动的药剂的性质。

52. 发明申请

US20090117064A1 STABLE VITAMIN B6 DERIVATIVE 审中-公开
标题翻译：稳定的维生素B6衍生物
公开(公告)号：US20090117064A1
公开(公告)日：2009-05-07
申请号：US12351424
申请日：2009-01-09
申请人： Keiji Sakamoto , Koichi Wada , Hajime Ito , Nobuhiro Take , Hiroshi Morimoto , Fumio Maniwa , Yukiko Shimmoto
发明人： Keiji Sakamoto , Koichi Wada , Hajime Ito , Nobuhiro Take , Hiroshi Morimoto , Fumio Maniwa , Yukiko Shimmoto
IPC分类号： A61K8/49 , A61K31/706 , A61Q19/02 , A23L1/48
CPC分类号： A61K8/673 , A23K20/174 , A23L33/15 , A61K31/66 , A61K31/706 , A61Q5/02 , A61Q19/00 , A61Q19/004 , A61Q19/005 , A61Q19/02 , A61Q19/08 , C07F9/58 , C07H17/02
摘要： A compound represented by the following general formula (I) or a salt thereof: wherein R1 represents a glycosyl group; R2 represents —CH2OH, —CHO, —CH2NH2, —CH2-amino acid residue, or —CH2—OPO2H; and R3 represents hydrogen atom, or —PO3H2, and methods of its use in cosmetics, medicaments, foodstuffs, and/or feeds.
摘要翻译：由以下通式（I）表示的化合物或其盐：其中R1表示糖基; R2表示-CH2OH，-CHO，-CH2NH2，-CH2-氨基酸残基或-CH2-OPO2H; 和R3表示氢原子，或-PO3H2，以及其用于化妆品，药物，食品和/或饲料中的方法。

53. 发明申请

US20070046400A1 Surface acoustic wave apparatus 失效
标题翻译：表面声波装置
公开(公告)号：US20070046400A1
公开(公告)日：2007-03-01
申请号：US11367555
申请日：2006-03-06
申请人： Koichi Wada , Seiichi Mitobe , Shogo Inoue
发明人： Koichi Wada , Seiichi Mitobe , Shogo Inoue
IPC分类号： H03H9/64
CPC分类号： H03H9/14532 , H03H9/02992 , H03H9/1452 , H03H9/14538 , H03H9/14547 , H03H9/6496
摘要： A surface acoustic wave apparatus has a configuration by which the spurious of the higher-order transverse modes is suppressed and a SAW excitation intensity distribution is not changed in the propagation direction. The surface acoustic wave apparatus has at least one interdigital transducer; a region with the plurality of interleaved comb-shaped electrodes is formed with two regions which are a first overlapping region and a second overlapping region with overlapping-lengths weighted along a propagation direction of a surface acoustic wave; the first overlapping region and the second overlapping region are in contact or overlapped in a direction vertical to the propagation direction of the surface acoustic wave; and in either the first or the second overlapping region, an overlapping-length weighting envelope curve has at least two or more changing points in the propagation direction of the surface acoustic wave.
摘要翻译：表面声波装置具有抑制高阶横模的杂散和SAW传播方向上的SAW激发强度分布不变化的结构。声表面波装置具有至少一个叉指式换能器; 具有多个交错梳状电极的区域形成有沿着声表面波的传播方向加权的具有重叠长度的第一重叠区域和第二重叠区域的两个区域; 第一重叠区域和第二重叠区域在与声表面波的传播方向垂直的方向上接触或重叠; 并且在第一或第二重叠区域中，重叠长度加权包络线在表面声波的传播方向上具有至少两个以上的变化点。

54. 发明授权

US07169849B2 Process for production of thermoplatic elastomer composition 有权
标题翻译：生产热塑性弹性体组合物的方法
公开(公告)号：US07169849B2
公开(公告)日：2007-01-30
申请号：US10480991
申请日：2002-06-13
申请人： Masaki Ikuji , Koichi Wada , Masanari Uno
发明人： Masaki Ikuji , Koichi Wada , Masanari Uno
IPC分类号： C08L53/02
CPC分类号： C08K5/14 , C08K5/0025 , C08L23/02 , C08L23/08 , C08L23/10 , C08L53/02 , C08L53/025 , C08L2666/06 , C08L2666/02
摘要： A process for production of a thermoplastic elastomer composition by melt-kneading a mixture in one step to thereby conduct dynamic crosslinking, wherein the mixture comprises a hydrogenated block copolymer (a1) which is prepared by hydrogenating a block copolymer comprising a vinyl aromatic polymer block (A1) and a conjugated diene polymer block (B1) and has number-average molecular weight of 200000 or above and, if necessary, a non-hydrogenated block copolymer (a2) comprising a vinyl aromatic polymer block (A2) and a conjugated diene polymer block (B2), and contains a non-aromatic rubber softening agent (b), a peroxide-crosslinkable olefin resin (c) having a density of 0.94 g/cm3 or above, a peroxide-decomposable olefin resin (d), an organic peroxide (e), and a crosslinking aid (f), the amount of (b) being 50 to 250 parts by mass per 100 parts by mass of the sum of (a1) +(a2), the amount of (c) being 2.5 to 50 parts by mass per 100 parts by mass of (a); and the amount of (d) being 0.5 to 10 times that of (c) by mass.
摘要翻译：一种制备热塑性弹性体组合物的方法，该方法是通过一步熔融捏合混合物，从而进行动态交联，其中该混合物包括氢化嵌段共聚物（一种<！ - SIPO < 包含乙烯基芳族聚合物嵌段（A 1 H 1）和共轭二烯聚合物嵌段（B 1 H 1）的共聚物，其数均分子量为200000以上，如果需要，包含乙烯基芳族聚合物嵌段（A 2 N 2）和共轭二烯聚合物嵌段（B 2 N 2）的非氢化嵌段共聚物（α2 H 2） >），并且含有非芳香族橡胶软化剂（b），密度为0.94g / cm 3以上的过氧化物可交联的烯烃树脂（c），过氧化物可分解的烯烃树脂（d），有机过氧化物（e）和交联助剂（f）中，（b）相对于（a 1 SUB / 1）的总和为100质量份为50〜250质量份 >）+（a _{2 ）（c）相对于（a）100质量份为2.5〜50质量份。（d）的量为（c）的0.5〜10倍。}

55. 发明授权

US07105599B2 Stretch material 有权
标题翻译：拉伸材料
公开(公告)号：US07105599B2
公开(公告)日：2006-09-12
申请号：US10479178
申请日：2002-05-28
申请人： Koichi Wada , Yosuke Jogo
发明人： Koichi Wada , Yosuke Jogo
IPC分类号： C08L53/02
CPC分类号： C08L53/025 , C08F8/04 , C08L23/04 , C08L23/06 , C08L23/10 , C08L25/04 , C08F297/04 , C08L2666/06 , C08L2666/02 , C08L2666/04
摘要： A stretch matenal consists essentially of a thermoplastic polymer matstial that meets the following couditions: (i) the thermoplastic polymer material contains: (a) 100 parts by weight of a hydrogenated block copolymer having a number average molecular weight of 50,000 to 140,000 and comprising am least two polymer blocks (A) composed mainly of a vinyl aromatic compound and at least one hydrogenated polymer block (B) composed mainly of a conjugated diene compound; (b) 0 to 120 parts by weight of a non-aromatic rubber softening agent; (c) 0 to 80 parts by weight of polyethylene that has an MFR of 15 g/10 min or above when measured at 190° C. wider a load of 2.16 kg; and (d) 0 to 40 parts by weight of polystyrene that has an MFR of 5 g/10 min or above when measured at 200° C. under a load of 5.00 kg.
摘要翻译：拉伸成型基本上由满足以下结构的热塑性聚合物基体组成：（i）热塑性聚合物材料包含：（a）100重量份数均分子量为50,000至140,000的氢化嵌段共聚物，并且包含主要由乙烯基芳族化合物和至少一种主要由共轭二烯化合物组成的氢化聚合物嵌段（B）组成的至少两个聚合物嵌段（A）（b）0〜120重量份的非芳香族橡胶软化剂; （c）0〜80重量份在190℃下测定MFR为15g / 10分钟以上的聚乙烯，2.16kg的负荷较宽; 和（d）0〜40重量份在500℃，5.00kg负荷下测定时MFR为5g / 10分钟以上的聚苯乙烯。

56. 发明授权

US06579125B1 Clip connector, method of attaching clip connector, and assembly of clip connector and support member 有权
标题翻译：夹子连接器，夹子连接器的连接方法以及夹子连接器和支撑件的组装
公开(公告)号：US06579125B1
公开(公告)日：2003-06-17
申请号：US09857686
申请日：2001-06-08
申请人： Takaya Nagahata , Koji Nishi , Shigeyoshi Ono , Yasuhiro Yoshikawa , Yoshinobu Kishimoto , Koichi Wada
发明人： Takaya Nagahata , Koji Nishi , Shigeyoshi Ono , Yasuhiro Yoshikawa , Yoshinobu Kishimoto , Koichi Wada
IPC分类号： H01R2400
CPC分类号： H01R12/721 , Y10S439/936
摘要： A clip connector (A) includes an insulating housing (1) and a plurality of terminals (2) projecting from the housing (1). The housing (1) includes an outer surface (1a) for engaging a support member such as a printed board. The outer surface (1a) is irregular, including a plurality of projecting portions (12) and a plurality of retreating portions (13). Each of the terminals (2) includes a straight portion (20a) and a bent portion (20b). Each of the straight portion (20a) is formed with a through-hole (22) through which a resin for bonding the support member and the outer surface (1a) is applied.
摘要翻译：夹子连接器（A）包括绝缘壳体（1）和从壳体（1）突出的多个端子（2）。壳体（1）包括用于接合诸如印刷板的支撑构件的外表面（1a）。外表面（1a）是不规则的，包括多个突出部分（12）和多个后退部分（13）。每个端子（2）包括直线部分（20a）和弯曲部分（20b）。每个直线部分（20a）形成有通孔（22），用于粘合支撑构件和外表面（1a）的树脂通过该通孔。

57. 发明授权

US06534044B1 Cosmetic preparation, surface-hydrophobized silica-coated metal oxide particles, sol of silica-coated metal oxide, and processes for producing these 有权
标题翻译：化妆品制备，表面疏水化二氧化硅涂覆的金属氧化物颗粒，二氧化硅涂覆的金属氧化物的溶胶及其制备方法
公开(公告)号：US06534044B1
公开(公告)日：2003-03-18
申请号：US09889048
申请日：2001-07-11
申请人： Koichi Wada , Nobuaki Ishii , Mitsuharu Irie , Kazuo Sekiguchi , Michihiro Takama
发明人： Koichi Wada , Nobuaki Ishii , Mitsuharu Irie , Kazuo Sekiguchi , Michihiro Takama
IPC分类号： A61K742
CPC分类号： A61K8/585 , A61K8/0212 , A61K8/11 , A61K8/19 , A61K8/25 , A61K8/27 , A61K8/28 , A61K8/29 , A61K2800/262 , A61K2800/413 , A61Q1/02 , A61Q1/06 , A61Q17/04 , A61Q19/00 , B01J13/0047 , B01J13/0069 , B01J13/02 , B01J13/22 , B82Y30/00 , C01P2004/62 , C01P2004/64 , C01P2006/12 , C09C1/043 , C09C1/3684 , C09C3/006 , C09C3/063 , C09C3/12
摘要： The invention relates to (1) a cosmetic material comprising silica-coated metal oxide particles further surface-treated with a hydrophobicizing agent, and (2) metal oxide particles having a specified infrared absorption spectrum intensity ratio and refractive index which are further treated with a hydrophobicizing agent, and to a process for their production. The invention further relates to a silica-coated metal oxide sol which gives such particles, and to a process for its production. The invention can give ultraviolet-screening cosmetic materials with an excellent transparent feel, wherein the particles are satisfactorily dispersed.
摘要翻译：本发明涉及（1）包含用疏水剂进一步表面处理的二氧化硅被覆的金属氧化物粒子的化妆品，（2）具有规定的红外吸收光谱强度比和折射率的金属氧化物粒子，其进一步用疏水剂，以及其生产方法。本发明还涉及给出这种颗粒的二氧化硅被覆金属氧化物溶胶及其制造方法。本发明可以赋予具有优异透明感的紫外线屏蔽化妆品材料，其中颗粒令人满意地分散。

58. 发明授权

US06454573B2 Board-cable connection structure 失效
标题翻译：板电缆连接结构
公开(公告)号：US06454573B2
公开(公告)日：2002-09-24
申请号：US09823760
申请日：2001-04-03
申请人： Hiroaki Hayashi , Takaya Nagahata , Hiroshi Fukumoto , Tokihiko Kishimoto , Koichi Wada
发明人： Hiroaki Hayashi , Takaya Nagahata , Hiroshi Fukumoto , Tokihiko Kishimoto , Koichi Wada
IPC分类号： H01R1200
CPC分类号： H05K3/365 , H01R12/515 , H01R12/721 , H01R12/79 , H01R12/85
摘要： An electrical connection structure includes a circuit board provided at an edge thereof with a plurality of external connection terminals, a flexible flat cable provided at an edge thereof with a plurality of connection terminals in corresponding relationship to the external connection terminals of the circuit board, and a corresponding number of clips. Each of the clips has a first clamping portion open in a first direction for inserting the circuit board, and a second clamping portion open in a second direction opposite to the first direction for inserting the flexible flat cable.
摘要翻译：电连接结构包括设置在其边缘处的多个外部连接端子的电路板，在其边缘处设置有与电路板的外部连接端子相对应的多个连接端子的柔性扁平电缆，以及相应数量的剪辑。每个夹子具有在第一方向上开放以插入电路板的第一夹持部分，以及在与第一方向相反的第二方向上开放以插入柔性扁平电缆的第二夹持部分。

59. 发明授权

US06238237B1 Connector 有权
标题翻译：连接器
公开(公告)号：US06238237B1
公开(公告)日：2001-05-29
申请号：US09381052
申请日：1999-09-13
申请人： Takaya Nagahata , Tokihiko Kishimoto , Koichi Wada , Shigemitsu Suzuki
发明人： Takaya Nagahata , Tokihiko Kishimoto , Koichi Wada , Shigemitsu Suzuki
IPC分类号： H04R1224
CPC分类号： H01R12/79 , H01R12/7011 , H01R12/7041 , H01R12/721
摘要： A connector (1) according to the present invention includes a housing (2) and terminal pins (3) mounted on the housing (2) for electrically connecting connection terminals (16) of a circuit board (15) to a conductor pattern of a flat cable (11). The housing (2) is bonded to the circuit board (15) by an adhesive for mechanical connection thereto. The housing (2) has a projection (5) which, together with the circuit board (15), forms a recess (17) for applying an adhesive thereto.
摘要翻译：根据本发明的连接器（1）包括壳体（2）和安装在壳体（2）上的端子销（3），用于将电路板（15）的连接端子（16）电连接到电路板扁平电缆（11）。壳体（2）通过用于与其连接的粘合剂粘合到电路板（15）。壳体（2）具有与电路板（15）一起形成用于向其施加粘合剂的凹部（17）的突起（5）。

60. 发明授权

US5929275A Catalyst and process for producing unsaturated aldehyde and unsaturated acid 失效
标题翻译：用于生产不饱和醛和不饱和酸的催化剂和方法
公开(公告)号：US5929275A
公开(公告)日：1999-07-27
申请号：US853215
申请日：1997-05-09
申请人： Koichi Wada , Akira Iwamoto , Yoshimasa Seo , Atsusi Sudo , Fumio Sakai , Kazuo Shiraishi , Hideaki Miki
发明人： Koichi Wada , Akira Iwamoto , Yoshimasa Seo , Atsusi Sudo , Fumio Sakai , Kazuo Shiraishi , Hideaki Miki
IPC分类号： B01J23/88 , B01J23/887 , B01J35/08 , B01J37/00 , B01J37/02 , C07B61/00 , C07C27/14 , C07C45/35 , C07C45/37 , C07C45/38 , C07C47/22 , C07C51/25 , C07C51/275 , C07C57/05 , C07C51/16 , B01J23/16 , C07C45/32
CPC分类号： C07C45/37 , B01J23/002 , B01J23/8876 , B01J37/0223 , C07C45/35 , C07C51/252 , B01J2523/00
摘要： A catalyst for the production of unsaturated aldehyde and unsaturated acid, obtained by loading a catalytically active component on a carrier and calcining the loaded catalyst, characterized by an average particle diameter of the catalyst of 4 to 16 mm, an average particle diameter of the carrier of 3 to 12 mm, a calcining temperature of 520 to 600.degree. C. and an amount of the catalytically active component loaded on the carrier of 5 to 80% by weight �weight of the catalytically active component)/(weight of the catalytically active component+weight of the carrier+weight of a strength improver)!, and a process for producing unsaturated aldehyde and unsaturated acid with the catalyst.
摘要翻译：用于生产不饱和醛和不饱和酸的催化剂，其通过将催化活性组分负载在载体上并煅烧负载的催化剂而获得，其特征在于催化剂的平均粒径为4至16mm，载体的平均粒径 3至12mm，煅烧温度为520-600℃，负载在载体上的催化活性组分的量为5-80重量％[催化活性组分的重量] /（催化活性组分的重量）组分+载体重量+强度改进剂的重量）]以及用催化剂生产不饱和醛和不饱和酸的方法。

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