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51. 发明授权

US5100901A Cyclic amine compounds and pharmaceutical use 失效
标题翻译：循环胺化合物和药物使用
公开(公告)号：US5100901A
公开(公告)日：1992-03-31
申请号：US423349
申请日：1989-10-18
申请人： Hachiro Sugimoto , Yutaka Tsuchiya , Kunizou Higurashi , Norio Karibe , Youichi Iimura , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Shin Araki , Takashi Kosasa , Atsuhiko Kubota , Michiko Kosasa , Kiyomi Yamatsu
发明人： Hachiro Sugimoto , Yutaka Tsuchiya , Kunizou Higurashi , Norio Karibe , Youichi Iimura , Atsushi Sasaki , Yoshiharu Yamanishi , Hiroo Ogura , Shin Araki , Takashi Kosasa , Atsuhiko Kubota , Michiko Kosasa , Kiyomi Yamatsu
IPC分类号： C07D211/18 , A61K31/452 , A61P25/02 , C07D207/09 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/32 , C07D211/34 , C07D211/44 , C07D211/70 , C07D211/76 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D471/04
CPC分类号： C07D401/06 , C07D207/09 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/32 , C07D211/34 , C07D211/44 , C07D211/70 , C07D211/76 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D471/04 , Y10S152/90
摘要： A cyclic amine compound is defined by the formula: ##STR1## in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is --(CHR22) r--, R22 being H or methyl, --CO-- (CHR22)r--, .dbd.(CH--CH.dbd.CH)b--, .dbd.CH--(CH2)c-- or .dbd.(CH--CH)d.dbd. and the ring including T and Q is piperidine. The compound is useful to treat senile dementia.

52. 发明授权

US09045240B2 Flight control device, spacecraft, and reference trajectory correcting method 有权
标题翻译：飞行控制装置，航天器和参考轨迹校正方法
公开(公告)号：US09045240B2
公开(公告)日：2015-06-02
申请号：US14131502
申请日：2012-07-11
申请人： Tetsuya Nagase , Atsushi Sasaki
发明人： Tetsuya Nagase , Atsushi Sasaki
IPC分类号： G01C23/00 , B64G1/24
CPC分类号： B64G1/242 , B64G1/24 , B64G1/62
摘要： A flight control method and device for correcting a reference trajectory based on a distance from a current position to a target position in a spacecraft in flight. A CPU included in the spacecraft generates a reference trajectory which is a trajectory for allowing the spacecraft in flight to arrive at the target position on a celestial body with the atmosphere, and which is identified based on velocity or energy of the spacecraft and on drag acceleration of the spacecraft. The CPU calculates a ratio between the range that is a distance from the current position based on the reference trajectory to the target position, and the real range that is a real distance from a current position to the target position, and corrects the reference trajectory by calculating the drag acceleration in the reference trajectory using the calculated ratio.
摘要翻译：一种飞行控制方法和装置，用于基于从飞行中的航天器中的当前位置到目标位置的距离来校正参考轨迹。包括在航天器中的CPU产生参考轨迹，该轨迹是允许飞行中的航天器到达具有大气的天体上的目标位置的轨迹，并且基于航天器的速度或能量以及拖曳加速度来识别的航天器。 CPU根据基准轨迹计算与当前位置距离的距离与目标位置之间的距离，以及作为从当前位置到目标位置的实际距离的实际范围，并将基准轨迹修正为使用计算的比率计算参考轨迹中的拖动加速度。

53. 发明授权

US08908246B2 Image reading device and method for reading an image with dummy interval 有权
标题翻译：以虚拟间隔读取图像的图像读取装置和方法
公开(公告)号：US08908246B2
公开(公告)日：2014-12-09
申请号：US13214982
申请日：2011-08-22
申请人： Atsushi Sasaki
发明人： Atsushi Sasaki
IPC分类号： H04N1/46 , H04N1/10 , H04N1/40
CPC分类号： H04N1/40056 , H04N1/1017 , H04N2201/04767
摘要： An image reading device has a light source and an image sensor configured to transfer an electric charge accumulated on an opto-electric conversion element to a shift register through a shift gate. A reading controller configured to control image reading inserts a dummy interval into a shift period for which the electric charge is transferred from the opto-electric conversion element so as to shift timing to start sensor reading on every line and to arrange peak positions of noise included in a read image differ from one another on every line.
摘要翻译：图像读取装置具有光源和图像传感器，该图像传感器被配置为通过移位门将累积在光电转换元件上的电荷传送到移位寄存器。配置为控制图像读取的读取控制器将虚拟间隔插入到从光电转换元件传送电荷的移位周期中，以便移位定时以在每行上开始传感器读取，并且布置包括的噪声的峰值位置读取图像在每条线上彼此不同。

54. 发明申请

US20120199827A1 THIN-FILM TRANSISTOR CIRCUIT SUBSTRATE AND METHOD OF MANUFACTURING THE SAME 有权
标题翻译：薄膜晶体管电路基板及其制造方法
公开(公告)号：US20120199827A1
公开(公告)日：2012-08-09
申请号：US13329545
申请日：2011-12-19
申请人： Tetsuya Shibata , Hajime Watakabe , Atsushi Sasaki , Yuki Matsuura , Muneharu Akiyoshi , Hiroyuki Watanabe
发明人： Tetsuya Shibata , Hajime Watakabe , Atsushi Sasaki , Yuki Matsuura , Muneharu Akiyoshi , Hiroyuki Watanabe
IPC分类号： H01L29/786 , H01L21/34
CPC分类号： H01L27/1225 , H01L29/66969 , H01L29/78606 , H01L29/7869
摘要： According to one embodiment, a method of manufacturing a thin-film transistor circuit substrate including forming an oxide semiconductor thin film above an insulative substrate, forming a gate insulation film and a gate electrode which are stacked on a first region of the oxide semiconductor thin film, and exposing from the gate insulation film a second region and a third region of the oxide semiconductor thin film, the second region and the third region being located on both sides of the first region of the oxide semiconductor thin film, forming an interlayer insulation film of silicon nitride including dangling bonds of silicon, the interlayer insulation film covering the second region and the third region of the oxide semiconductor thin film, the gate insulation film and the gate electrode, and forming a source electrode and a drain electrode.
摘要翻译：根据一个实施例，制造薄膜晶体管电路衬底的方法包括在绝缘衬底上形成氧化物半导体薄膜，形成栅极绝缘膜和栅电极，所述栅极绝缘膜和栅电极层叠在氧化物半导体薄膜的第一区域上并且从所述栅极绝缘膜暴露所述氧化物半导体薄膜的第二区域和第三区域，所述第二区域和所述第三区域位于所述氧化物半导体薄膜的所述第一区域的两侧，形成层间绝缘膜包括硅的悬挂键，覆盖第二区域的层间绝缘膜和氧化物半导体薄膜的第三区域，栅极绝缘膜和栅电极，以及形成源电极和漏电极。

55. 发明授权

US07612114B2 Selective estrogen receptor modulator 有权
标题翻译：选择性雌激素受体调节剂
公开(公告)号：US07612114B2
公开(公告)日：2009-11-03
申请号：US11158245
申请日：2005-06-22
申请人： Shinichi Hamaoka , Noritaka Kitazawa , Kazumasa Nara , Atsushi Sasaki , Atsushi Kamada , Tadashi Okabe
发明人： Shinichi Hamaoka , Noritaka Kitazawa , Kazumasa Nara , Atsushi Sasaki , Atsushi Kamada , Tadashi Okabe
IPC分类号： A61K31/136 , C07C211/44
CPC分类号： C07C217/22 , C07C215/78 , C07C217/18 , C07C217/78 , C07C217/84 , C07C219/34 , C07C323/25 , C07C2602/10 , C07D205/04 , C07D207/09 , C07D209/08 , C07D209/14 , C07D209/30 , C07D209/44 , C07D211/14 , C07D211/26 , C07D211/46 , C07D211/58 , C07D213/38 , C07D213/64 , C07D213/73 , C07D223/16 , C07D243/08 , C07D277/66 , C07D295/088 , C07D295/13 , C07D295/135 , C07D307/14 , C07D309/04 , C07D309/14 , C07D311/58 , C07D317/66 , C07D333/20 , C07D333/58 , C07D405/12 , C07D451/06 , C07D453/02 , C07D487/08 , C07D491/10 , C07F5/025 , C07F7/1804 , C07F7/2208
摘要： The present invention provides a compound represented by the following formula (I); [wherein T represents a single bond, a C1-C4 alkylene group which may have a substituent and the like; formula (I-1) represents a single bond or a double bond; A represents a single bond, a bivalent 5- to 14-membered heterocyclic group which may have a substituent and the like; Y represents a single bond and the like; Z represents a methylene group and the like; ring G represents a phenylene group and the like which may condense with a 5- to 6-membered ring and may have a heteroatom; Ra and Rb are the same as or different from each other and represent a hydrogen atom and the like; W represents a single bond and the like; R′ represents 1 to 4 independent hydrogen atoms and the like; and R″ represents 1 to 4 independent hydrogen atoms and the like] or a salt thereof, or a hydrate thereof.
摘要翻译：本发明提供由下式（I）表示的化合物。 [其中T表示单键，可以具有取代基的C1-C4亚烷基等; “img id =”CUSTOM-CHARACTER-00001“he =”3.56mm“wi =”21.84mm“file =”US07612114-20091103-P00001.TIF“alt =”custom character“img-content =”character“img-format =“tif”/>式（I-1）表示单键或双键; A表示单键，可以具有取代基的二价5〜14元杂环基等; Y表示单键等; Z表示亚甲基等; 环G表示可以用5-至6-元环缩合并可具有杂原子的亚苯基等; R a和R b彼此相同或不同，表示氢原子等; W表示单键等; R'表示1〜4个独立的氢原子等; R“表示1〜4个独立的氢原子等]或其盐或其水合物。

56. 发明授权

US07538123B2 Indole derivative having piperidine ring 失效
标题翻译：具有哌啶环的吲哚衍生物
公开(公告)号：US07538123B2
公开(公告)日：2009-05-26
申请号：US11579903
申请日：2005-05-11
申请人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
发明人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
IPC分类号： A61K31/454
CPC分类号： C07D491/08 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. This compound has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor, and is useful as an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage.
摘要翻译：本发明涉及由下式表示的化合物，其药理学可接受的盐或其作为药物的用途：其中R 1和R 2是彼此相邻的取代基，并且与它们各自连接的两个碳原子一起形成可被1〜4个选自（1）氧代基，（2）羟基等的取代基取代的5〜7元非芳族碳环基等。 R3表示氢原子等; R6表示氢原子等。该化合物与5-HT 1A受体的结合强度优异，对受体具有拮抗作用，可用作治疗或预防下尿路症状的药剂，特别是有关尿液储存的症状。

57. 发明申请

US20080119518A1 1-(Piperidin-4- Yl)-1H-Indole Derivatives 审中-公开
标题翻译： 1-（哌啶-4-基）-1H-吲哚衍生物
公开(公告)号：US20080119518A1
公开(公告)日：2008-05-22
申请号：US11795923
申请日：2006-02-02
申请人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Daisuke Shinmyo , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
发明人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Daisuke Shinmyo , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
IPC分类号： A61K31/4545 , A61K31/454 , C07D403/14
CPC分类号： C07D401/04 , C07D401/14
摘要： The present invention provides a compound represented by the formula (1) or a pharmacologically acceptable salt thereof, or a hydrate thereof (provided that a compound in which all of R4a, R4b, and R4c are hydrogen atoms is excluded.): [wherein R1 represents a hydrogen atom, R2 represents a hydrogen atom, R3 represents the formula: wherein R4a, R4b, and R4c are the same as or different from each other and each represents a hydrogen atom, a C1-6 alkyl group or a C1-6 alkoxy group, etc.]
摘要翻译：本发明提供由式（1）表示的化合物或其药理学上可接受的盐或其水合物（不包括其中R4a，R4b和R4c全部为氢原子的化合物。）：[其中R 1 表示氢原子，R2表示氢原子，R3表示下式：其中R4a，R4b和R4c彼此相同或不同，各自表示氢原子，C 1-6 >烷基或C 1-6烷氧基等]

58. 发明申请

US20050256103A1 Indole derivative having piperidine ring 审中-公开
标题翻译：具有哌啶环的吲哚衍生物
公开(公告)号：US20050256103A1
公开(公告)日：2005-11-17
申请号：US11126209
申请日：2005-05-11
申请人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
发明人： Yuichi Suzuki , Koichi Ito , Atsushi Sasaki , Koshi Ueno , Miyuki Sakai , Hiroki Ishihara , Atsuhiko Kubota
IPC分类号： A61K31/454 , A61K31/4725 , A61K31/536 , A61K31/55 , A61K31/553 , A61P13/02 , A61P13/10 , A61P43/00 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14 , C07D491/08 , C07D41/14 , C07D43/14
CPC分类号： C07D491/08 , C07D401/04 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to a compound represented by the following formula, a pharmacologically acceptable salt thereof, or a use thereof as a pharmaceutical: wherein R1 and R2 are substituents adjacent to each other, and together with two carbon atoms to each of which they attach, form a 5- to 7-membered non-aromatic carbocyclic group or the like, which may be substituted by 1 to 4 substituents selected from (1) an oxo group, (2) a hydroxyl group, and the like; R3 represents a hydrogen atom or the like; and R6 represents a hydrogen atom or the like. It is an object of the present invention to discover an agent for treating or preventing lower urinary tract symptoms, and particularly symptoms regarding urinary storage, which has a superior strength of binding to a 5-HT1A receptor and an antagonism to the receptor.
摘要翻译：本发明涉及由下式表示的化合物，其药理学上可接受的盐或其作为药物的用途：其中R 1和R 2是相邻的取代基并且与它们各自连接的两个碳原子一起形成5-至7-元非芳族碳环基等，其可以被1至4个选自以下的取代基取代：（1）氧代基团，（2）羟基等; R 3表示氢原子等; R 6表示氢原子等。本发明的目的是发现用于治疗或预防下尿路症状的药剂，特别是关于尿液储存的症状，其具有优于5-HT 1A受体的结合强度和对受体的拮抗作用。

59. 发明授权

US06875761B2 Certain 1,3-disubstituted isoquinoline derivatives 失效
标题翻译：某些1,3-二取代异喹啉衍生物
公开(公告)号：US06875761B2
公开(公告)日：2005-04-05
申请号：US10796673
申请日：2004-03-10
申请人： Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
发明人： Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
IPC分类号： C07D217/22 , C07D217/24 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/04 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/10 , C07D495/04 , A61K31/33 , A61K31/47 , A61K31/495 , C07D217/00 , C07D241/04
CPC分类号： C07D401/04 , C07D217/22 , C07D217/24 , C07D401/06 , C07D401/10 , C07D401/12 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/04 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/10 , C07D495/04
摘要： Condensed pyridine compounds represented by formula (I): wherein: R1 and R3 are, independently, hydrogen, lower alkyl, or lower alkoxy; R2 represent an amino substituent; ring A is a benzene ring, pyridine ring, thiophene ring, or furan ring; and B represents a substituent containing a ring structure. Also, pharmaceutically acceptable salt and hydrates thereof. These compounds are clinically useful medicaments having serotonin antagonism, and in particular, for treating, ameliorating, or preventing spastic paralysis. They are also useful as central muscle relaxants for ameliorating myotonia.
摘要翻译：由式（I）表示的缩合吡啶化合物：其中：R 1和R 3独立地是氢，低级烷基或低级烷氧基; R 2表示氨基取代基; 环A为苯环，吡啶环，噻吩环或呋喃环; B表示含有环结构的取代基。此外，其药学上可接受的盐和水合物。这些化合物是具有5-羟色胺拮抗作用的临床上有用的药物，特别是用于治疗，改善或预防痉挛性麻痹。它们也可用作改善肌强直的中枢肌肉松弛剂。

60. 发明授权

US06340759B1 Fused pyridine derivatives 失效
标题翻译：融合吡啶衍生物
公开(公告)号：US06340759B1
公开(公告)日：2002-01-22
申请号：US09509778
申请日：2000-03-31
申请人： Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
发明人： Kohshi Ueno , Atsushi Sasaki , Koki Kawano , Tadashi Okabe , Noritaka Kitazawa , Keiko Takahashi , Noboru Yamamoto , Yuichi Suzuki , Manabu Matsunaga , Atsuhiko Kubota
IPC分类号： C07D24102
CPC分类号： C07D401/04 , C07D217/22 , C07D217/24 , C07D401/06 , C07D401/10 , C07D401/12 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/14 , C07D413/10 , C07D417/04 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/10 , C07D495/04
摘要： The present provides a condensed pyridine compound (I) represented by the following formula: (wherein, R2 represents ring A represents benzene ring, pyridine ring, thiophene ring or furan ring; and B represents its pharmaceutically acceptable salt or hydrates thereof, which is a clinically useful medicament having a serotonin antagonism, in particular, that for treating, ameliorating or preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.
摘要翻译：本发明提供由下式表示的缩合吡啶化合物（I）（其中，R2表示A表示苯环，吡啶环，噻吩环或呋喃环; B表示其药学上可接受的盐或水合物，其为临床上有用的药物具有5-羟色胺拮抗作用，特别是用于治疗，改善或预防痉挛性麻痹或用于改善肌强直的中枢肌肉松弛剂。

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