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51. 发明授权

US06641230B2 Anti-locking brake system for a land vehicle 有权
公开(公告)号：US06641230B2
公开(公告)日：2003-11-04
申请号：US09962010
申请日：2001-09-24
申请人： Helmut Gegalski , Thomas Wald , Josef Knechtgens , Thomas Bach , Andreas Marx , Frank Heller , Michael Schwarz , Thomas Wagner
发明人： Helmut Gegalski , Thomas Wald , Josef Knechtgens , Thomas Bach , Andreas Marx , Frank Heller , Michael Schwarz , Thomas Wagner
IPC分类号： B60T848
CPC分类号： F16K39/024 , B60T8/363 , B60T8/4872 , B60T8/4881 , B60T8/5037 , Y10S303/90
摘要： An anti-locking brake system for a land vehicle, which is set up in particular for traction control and vehicle dynamics control, comprises a pump (42) for actuating a wheel brake (37) which removes brake fluid from a brake pressure generating unit (31) and supplies it to the wheel brake (37), wherein a first valve arrangement (1) blocks in a non-actuated (normal) position (1.1) the connection between the brake pressure generating unit (31) and an input connection (42e) of the pump (42) and in at least one actuated position (1.3) establishes a primary flow connection (A), a first electromagnetic valve (50) establishes in a non-actuated position (50.1) the connection between an output connection (42a) of the pump (42) and the brake pressure generating unit (31), and blocks it in an actuated position (50.2), a second electromagnetic valve (39) blocks the connection between the wheel brake (37) and the input connection (42e) of the pump (42) in a non-actuated position, and in an actuated position establishes it, and a third electromagnetic valve (38) establishes the connection between the output connection (42a) of the pump (42) and the wheel brake (37) in a non-actuated position (38.1) and blocks it in an actuated position (38.2). To generate a more accurate pressure modulation during the operating phase “maintain pressure” (II), the third electromagnetic valve (38) is in the actuated position during said operating phase.

52. 发明授权

US5970588A Unlockable snap fastener 失效
标题翻译：可开锁的紧固件
公开(公告)号：US5970588A
公开(公告)日：1999-10-26
申请号：US101744
申请日：1998-07-16
申请人： Winifred Hurtz , Michael Schwarz
发明人： Winifred Hurtz , Michael Schwarz
IPC分类号： A44B17/00
CPC分类号： A44B17/0076 , Y10T24/45733 , Y10T24/45749 , Y10T24/45754
摘要： A snap closure with a male part whose male coupling surfaces have an enlarged closing head at a closing neck, with a two-part female part comprising a housing having an insertion hole for the male coupling surfaces, and with two plate-shaped slides which are identical in shape, spring-loaded in opposite directions, project out on opposite sides of the housing by their outer ends which serve for actuation, and can be pressed in against the spring loading in opposite directions relative to one another transverse to the insertion hole, wherein, on the one hand, the two slides have, in their mutual joint region, complementing closing parts for a common locking profile which engages behind the inserted closing head of the male part when coupling, and, on the other hand, are cut out and have a common release profile for decoupling the closing head, wherein each of the two slides which are made of elastic material are provided at their inner ends with a longitudinally elastic spring portion formed integral with the slides, and in that the free ends of these spring portions are supported alternately at the two slides.
摘要翻译： PCT No.PCT / EP96 / 05677 371日期：1998年7月16日 102（e）日期1998年7月16日PCT提交1996年12月8日PCT公布。公开号WO97 / 28714 日期1997年8月14日具有凸形部件的弹性闭合件，其凸形耦合表面在闭合颈部处具有扩大的闭合头部，两部分凹部分包括具有用于阳联接表面的插入孔的壳体，以及两个板形状相同的弹簧，其弹簧加载在相反的方向上，通过其外端在壳体的相对侧上伸出，用于致动，并且可以相对于彼此横向地以相反的方向压靠弹簧加载一方面，两个滑块在它们的相互接合区域中具有用于共同的锁定轮廓的互补闭合部件，该共同的锁定轮廓在联接时接合在阳性部件的插入的闭合头部后面，并且在另一个上手部被切出并且具有用于使闭合头解耦的公共释放轮廓，其中由弹性材料制成的两个滑块中的每一个在其内端处设置有纵向弹性 c弹簧部分与滑块形成一体，并且这些弹簧部分的自由端交替地支撑在两个滑块上。

53. 发明授权

US5968482A .alpha.-hydroxyketoalkyl derivatives as light protection filters 失效
标题翻译： α-羟基酮烷基衍生物作为防光过滤器
公开(公告)号：US5968482A
公开(公告)日：1999-10-19
申请号：US710767
申请日：1996-09-20
申请人： Roland Martin , Ingeborg Stein , Ulrich Heywang , Michael Schwarz , Thekla Kurz
发明人： Roland Martin , Ingeborg Stein , Ulrich Heywang , Michael Schwarz , Thekla Kurz
IPC分类号： A61K8/00 , A61K8/35 , A61K8/37 , A61K8/49 , A61K31/12 , A61K31/125 , A61K31/19 , A61K31/216 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/53 , A61P17/00 , A61P17/16 , A61P29/00 , A61P35/00 , A61Q17/04 , A61Q19/00 , C07C49/747 , C07C49/753 , C07C49/83 , C07C49/835 , C07C69/738 , C07D235/18 , C07D251/12 , C07D251/26 , C07D487/08 , C09K3/00 , A61K7/42 , A01N43/66 , C07C49/00 , C07D251/00
CPC分类号： C07D251/26 , A61K8/35 , A61K8/37 , A61K8/4946 , A61K8/4966 , A61Q17/04 , C07C49/747 , C07C49/753 , C07C49/83 , C07C49/835 , C07C69/738 , C07D235/18 , A61K2800/57 , Y10S514/844
摘要： The invention relates to the use of .alpha.-hydroxyketoalkyl derivatives as light protection filters for cosmetic or pharmaceutical products, the .alpha.-hydroxyketoalkyl group being linked, if appropriate via a spacer, to a chromophoric group which has an absorption maximum in a wavelength range of between 280 and 400 nm and has a conjugated .pi.-electron system of at least 8 .pi.-electrons, and to new .alpha.-hydroxyalkyl derivatives, processes for their preparation and pharmaceutical and cosmetic formulations comprising these derivatives as light protection substances.
摘要翻译：本发明涉及α-羟基酮烷基衍生物作为化妆品或药物产品的防光过滤器的用途，α-羟基酮烷基如果适当地通过间隔基连接到发色团上，发色团的波长范围在具有至少8个π电子的共轭π电子系统和新的α-羟基烷基衍生物，其制备方法以及包含这些衍生物作为防光物质的药物和化妆品制剂。

54. 发明授权

US5847152A Preparation of a D-(+)-biotin intermediate 失效
标题翻译：制备D - （+） - 生物素中间体
公开(公告)号：US5847152A
公开(公告)日：1998-12-08
申请号：US702450
申请日：1996-09-26
申请人： Jurgen Eckstein , Thomas Koppe , Michael Schwarz , Michael Casutt
发明人： Jurgen Eckstein , Thomas Koppe , Michael Schwarz , Michael Casutt
IPC分类号： A61K31/415 , C07D495/04
CPC分类号： C07D495/04
摘要： The present invention relates to an improved process for making heterocyclic compounds suitable for intermediate products for making D-(+)-biotin and a process for making D-(+)-biotin itself.
摘要翻译： PCT No.PCT / EP95 / 00593 Sec。 371日期1996年9月26日 102（e）1996年9月26日PCT提交1995年2月18日PCT公布。第WO95 / 26965号公报日期1995年10月12日本发明涉及一种制备适于制备D - （+） - 生物素的中间产物的杂环化合物的改进方法和制备D - （+） - 生物素本身的方法。

55. 发明授权

US5721258A Primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases 失效
标题翻译：氟吡汀在神经退行性疾病中的初级和次级神经保护作用
公开(公告)号：US5721258A
公开(公告)日：1998-02-24
申请号：US602742
申请日：1996-04-19
申请人： Michael Schwarz , Gabriela Pergande , Jurgen Engel , Bernd Nickel , Heinz Ulrich , Stefan Szelenyi
发明人： Michael Schwarz , Gabriela Pergande , Jurgen Engel , Bernd Nickel , Heinz Ulrich , Stefan Szelenyi
IPC分类号： C07D213/75 , A61K31/44 , A61P25/00
CPC分类号： A61K31/44
摘要： The NMDA-antagonistic effect of flupirtine permits the preparation of medicaments for the treatment of cerebral ischemia, neurodegenerative disorders, traumatic brain and bone marrow damage, and other illnesses.
摘要翻译： PCT No.PCT / EP94 / 02649 371日期：1996年04月19日 102（e）1996年4月19日PCT PCT 1994年8月10日PCT公布。公开号WO95 / 05175 日期1995年2月23日氟吡汀的NMDA拮抗作用允许制备药物用于治疗脑缺血，神经变性疾病，创伤性脑和骨髓损伤等疾病。

56. 发明授权

US5677314A Bis(methylidene)phenylene derivatives 失效
标题翻译：双（亚甲基）亚苯基衍生物
公开(公告)号：US5677314A
公开(公告)日：1997-10-14
申请号：US563796
申请日：1995-11-28
申请人： Inge Stein , Michael Schwarz , Ulrich Heywang , Michael Kompter
发明人： Inge Stein , Michael Schwarz , Ulrich Heywang , Michael Kompter
IPC分类号： A61K8/35 , A61K8/49 , A61K31/12 , A61K31/445 , A61Q17/04 , C07C45/51 , C07C45/68 , C07C45/74 , C07C49/683 , C07C49/757 , C07C309/23 , C07C309/24 , C07D235/18 , C07D453/02 , A61K31/46
CPC分类号： A61Q17/04 , A61K8/35 , A61K8/4926 , A61K8/4946 , C07C45/513 , C07C45/74 , C07C49/683 , C07C49/757 , C07D453/02
摘要： The invention relates to bis(methylidene)phenylene derivatives of the formula A.sup.1 -Phe-A.sup.2 I wherein Phe is an unsubstituted or substituted phenylene group, A.sup.1 is a group selected from the formulae 1, 2 and 3 and A.sup.2 is a group other than A.sup.1 selected from the formulae 1, 2 and 3 ##STR1## wherein R.sup.1 and R.sup.2 are independently H or CH.sub.3 and their preparation and use as UV filters, in particular cosmetic and pharmaceutical preparations.
摘要翻译：本发明涉及式A1-Phe-A2I的双（亚甲基）亚苯基衍生物，其中Phe是未取代或取代的亚苯基，A1是选自式1,2和3的基团，A2是除A1以外的基团，选自配方1,2和3，其制备和用作UV过滤器，特别是化妆品和药物制剂。

57. 发明授权

US5529170A Feed screw for sedimentation or treatment systems 失效
标题翻译：进料螺杆用于沉淀或处理系统
公开(公告)号：US5529170A
公开(公告)日：1996-06-25
申请号：US375858
申请日：1995-01-20
申请人： Michael Schwarz , Helmut Pfeifhofer
发明人： Michael Schwarz , Helmut Pfeifhofer
IPC分类号： B01D21/24 , B65G33/26
CPC分类号： B01D21/2461 , B65G33/265
摘要： The invention concerns a feed screw in the form of a self-supporting, axleless helix whose surface extends essentially radially, the feed screw being used in sedimentation or treatment systems for clearing suspensions in paper making processes. The invention is characterized by a second helix whose surface, or generatrix, deviates preferably between 0.degree. and 20.degree. from the direction of the central axis and extends in the feed direction. The second helix may deviate between 0.degree. and maximally 40.degree. and have a length--per lead--between 20% and 40% of the lead of the helices.
摘要翻译：本发明涉及一种自支撑的无轴螺旋形式的进料螺杆，其表面基本上径向延伸，进料螺杆用于沉淀或处理系统中，用于清除造纸过程中的悬浮液。本发明的特征在于第二螺旋，其表面或母线优选地从中心轴线的方向偏离0°至20°，并在进给方向上延伸。第二螺旋可以在0°和最大40°之间偏离，并且具有每个引线的长度 - 螺旋的引线的20％和40％之间。

58. 发明授权

US5457265A Process and means for the oxidative destruction of azides 失效
标题翻译：氧化破坏叠氮化物的方法和方法
公开(公告)号：US5457265A
公开(公告)日：1995-10-10
申请号：US94728
申请日：1993-07-21
申请人： Arnulf Heubner , Michael Schwarz , Bernd Reckmann
发明人： Arnulf Heubner , Michael Schwarz , Bernd Reckmann
IPC分类号： C01B21/08 , A62D3/38 , A62D101/45 , C02F1/76 , A62D3/00
CPC分类号： A62D3/38 , A62D2101/45 , Y10S210/903
摘要： The invention relates to a process and means for the oxidative destruction of azides. The process is characterized in that the azide-containing solutions to be disposed of are treated with an iodine solution in the presence of an iodide and a thiosulfate. The means are preferably employed in the form of tablets.
摘要翻译：本发明涉及一种氧化破坏叠氮化物的方法和方法。该方法的特征在于，在碘化物和硫代硫酸盐存在下，用碘溶液处理待处置的含叠氮化物溶液。该方法优选以片剂的形式使用。

59. 发明授权

US5235065A Process for the preparation of a D-(+)-biotin intermediate 失效
标题翻译：制备D-（+） - 生物素中间体的方法
公开(公告)号：US5235065A
公开(公告)日：1993-08-10
申请号：US846105
申请日：1992-03-05
申请人： Michael Schwarz , Michael Casutt , Jurgen Eckstein
发明人： Michael Schwarz , Michael Casutt , Jurgen Eckstein
IPC分类号： A61K31/415 , A61P3/02 , C07D495/04 , C07F1/02 , C07F3/02
CPC分类号： C07D495/04 , C07F1/02 , C07F3/02
摘要： The present invention relates to a process for the preparation of heterocyclic compounds which are suitable as intermediates for the preparation of D-(+)-biotin, and to a process for the preparation of D-(+)-biotin itself. The invention further relates to intermediates in this process.
摘要翻译：本发明涉及适合作为制备D - （+） - 生物素的中间体的杂环化合物的制备方法以及制备D - （+） - 生物素本身的方法。本发明还涉及该方法中的中间体。

60. 发明授权

US5180837A Pilosinine derivatives 失效
标题翻译：吡啶啉衍生物
公开(公告)号：US5180837A
公开(公告)日：1993-01-19
申请号：US781608
申请日：1991-10-23
申请人： Ulrich Heywang , Michael Casutt , Michael Schwarz
发明人： Ulrich Heywang , Michael Casutt , Michael Schwarz
IPC分类号： A61K31/415 , A61P27/02 , B01J25/02 , C07B61/00 , C07D233/58 , C07D241/18 , C07D405/06
CPC分类号： C07D405/06
摘要： The invention relates to a process for the preparation of racemic pilosinine derivatives as precursor for the alkaloid pilocarpine of pharmacological importance from a 5-formyl-1-alkylimidazole of the formula I ##STR1## in which R.sup.1 is a straight-chain or branched alkyl chain with 1-6 C atoms which, via the stage of the thioacetal, is added onto .gamma.-crotonolactone.
摘要翻译：本发明涉及一种制备作为具有药理重要性的生物碱毛果芸香碱的前体的外消旋的四环素衍生物的方法，其由式I的5-甲酰基-1-烷基咪唑制备，其中R 1是直链或支链烷基具有1-6个C原子的链，其通过硫代缩醛的阶段加入到γ-内酯内。

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