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51. 发明申请

US20070009203A1 MULTI-STABLE MICRO ELECTROMECHANICAL SWITCHES AND METHODS OF FABRICATING SAME 失效
标题翻译：多稳态微机电开关及其制造方法
公开(公告)号：US20070009203A1
公开(公告)日：2007-01-11
申请号：US11532689
申请日：2006-09-18
申请人： Rogier Receveur , Philippe Habets , Ralph Danzl , Richard Houben , Michael Mattes
发明人： Rogier Receveur , Philippe Habets , Ralph Danzl , Richard Houben , Michael Mattes
IPC分类号： G02B6/26
CPC分类号： H01H59/0009 , B81B3/0054 , B81B2201/018 , B81B2203/051 , H01H2001/0042 , H01H2001/0078 , Y10T29/49105
摘要： A micro electromechanical (MEMS) switch suitable for use in medical devices is provided, along with methods of producing and using MEMS switches. In one aspect, a micro electromechanical switch including a moveable member configured to electrically cooperate with a receiving terminal is formed on a substrate. The moveable member and the receiving terminal each include an insulating layer proximate to the substrate and a conducting layer proximate to the insulating layer opposite the substrate. In various embodiments, the conducting layers of the moveable member and/or receiving terminal include a protruding region that extends outward from the substrate to switchably couple the conducting layers of the moveable member and the receiving terminal to thereby form a switch. The switch may be actuated using, for example, electrostatic energy.
摘要翻译：提供了适用于医疗设备的微机电（MEMS）开关，以及生产和使用MEMS开关的方法。一方面，在基板上形成包括被配置为与接收端子电配合的可移动部件的微机电开关。可移动构件和接收端子各自包括靠近衬底的绝缘层和靠近与衬底相对的绝缘层的导电层。在各种实施例中，可移动构件和/或接收端子的导电层包括从基板向外延伸的可突出地连接可移动构件和接收端子的导电层从而形成开关的突出区域。可以使用例如静电能来致动开关。

52. 发明授权

US09132268B2 Miniaturized feedthrough 有权
标题翻译：小型化馈通
公开(公告)号：US09132268B2
公开(公告)日：2015-09-15
申请号：US11948673
申请日：2007-11-30
申请人： Rogier Receveur
发明人： Rogier Receveur
IPC分类号： A61N1/375 , A61N1/05
CPC分类号： A61N1/05 , A61N1/3754
摘要： Formation of a feedthrough in a substrate for use in an implantable medical device is presented. A substrate includes a first surface and a second surface, and a via that extends through the first and the second surfaces. A dielectric layer is formed over one of a first surface of the substrate. Conductive material is introduced into the via to form a feedthrough.
摘要翻译：提出了在可植入医疗装置中使用的基板中的馈通的形成。衬底包括第一表面和第二表面，以及延伸穿过第一表面和第二表面的通孔。介电层形成在衬底的第一表面之一上。将导电材料引入通孔以形成馈通。

53. 发明授权

US08569633B2 Feedthrough for microelectromechanical system 有权
标题翻译：微机电系统馈通
公开(公告)号：US08569633B2
公开(公告)日：2013-10-29
申请号：US11949005
申请日：2007-11-30
申请人： Rogier Receveur , Michael A. Schugt , William J. Taylor , Brad C. Tischendorf
发明人： Rogier Receveur , Michael A. Schugt , William J. Taylor , Brad C. Tischendorf
IPC分类号： H05K7/00
CPC分类号： A61N1/05 , A61N1/3754
摘要： A hermetically sealed microelectromechanical system (MEMS) package for an implantable medical device is presented. The MEMS comprises a first substrate that includes an aperture. A feedthrough assembly is coupled to the aperture, the feedthrough assembly comprises a conductive element housed in a glass insulator member. A second substrate is coupled to the first substrate.
摘要翻译：介绍了一种用于可植入医疗器械的气密密封微机电系统（MEMS）封装。 MEMS包括包括孔的第一衬底。馈通组件联接到孔，馈通组件包括容纳在玻璃绝缘体构件中的导电元件。第二衬底耦合到第一衬底。

54. 发明申请

US20110072646A1 WAFER LEVEL HERMETICALLY SEALED MEMS DEVICE 审中-公开
标题翻译： WAFER LEVEL HERMETICALY SEALED MEMS DEVICE
公开(公告)号：US20110072646A1
公开(公告)日：2011-03-31
申请号：US12907615
申请日：2010-10-19
申请人： Rogier Receveur , Cornel Marxer
发明人： Rogier Receveur , Cornel Marxer
IPC分类号： H01H11/00
CPC分类号： B81C1/0023 , B81B7/007 , B81C2203/0109 , Y10T29/49105
摘要： A hermetically sealed microelectromechanical system (MEMS) package includes a MEMS switch having a movable portion and a stationary portion with an electrical contact thereon. A glass lid is anodically bonded to the MEMS switch to form a sealed cavity over the movable portion of the MEMS switch. The glass lid includes a contact aperture to allow access to the electrical contact on the stationary portion of the MEMS switch. A family of body-implantable hermetically-sealed MEMS packages are provided according to certain aspects and embodiments of the present invention.
摘要翻译：密封的微机电系统（MEMS）封装包括具有可移动部分的MEMS开关和在其上具有电接触的固定部分。玻璃盖阳极结合到MEMS开关，以在MEMS开关的可移动部分上形成密封空腔。玻璃盖包括接触孔，以允许接近MEMS开关的固定部分上的电接触。根据本发明的某些方面和实施例提供了一系列可植入人体的气密密封的MEMS封装。

55. 发明申请

US20100155204A1 MULTI-STABLE MICRO ELECTROMECHANICAL SWITCHES AND METHODS OF FABRICATING SAME 有权
标题翻译：多稳态微机电开关及其制造方法
公开(公告)号：US20100155204A1
公开(公告)日：2010-06-24
申请号：US12717406
申请日：2010-03-04
申请人： Rogier Receveur , Philippe Habets , Ralph B. Danzl , Richard P.M. Houben , Michael F. Mattes
发明人： Rogier Receveur , Philippe Habets , Ralph B. Danzl , Richard P.M. Houben , Michael F. Mattes
IPC分类号： H01H59/00 , H01H11/00
CPC分类号： H01H59/0009 , B81B3/0054 , B81B2201/018 , B81B2203/051 , H01H2001/0042 , H01H2001/0078 , Y10T29/49105
摘要： A micro electromechanical (MEMS) switch suitable for use in medical devices is provided, along with methods of producing and using MEMS switches. In one aspect, a micro electromechanical switch including a moveable member configured to electrically cooperate with a receiving terminal is formed on a substrate. The moveable member and the receiving terminal each include an insulating layer proximate to the substrate and a conducting layer proximate to the insulating layer opposite the substrate. In various embodiments, the conducting layers of the moveable member and/or receiving terminal include a protruding region that extends outward from the substrate to switchably couple the conducting layers of the moveable member and the receiving terminal to thereby form a switch. The switch may be actuated using, for example, electrostatic energy.
摘要翻译：提供了适用于医疗设备的微机电（MEMS）开关，以及生产和使用MEMS开关的方法。一方面，在基板上形成包括被配置为与接收端子电配合的可移动部件的微机电开关。可移动构件和接收端子各自包括靠近衬底的绝缘层和靠近与衬底相对的绝缘层的导电层。在各种实施例中，可移动构件和/或接收端子的导电层包括从基板向外延伸的可突出地连接可移动构件和接收端子的导电层从而形成开关的突出区域。可以使用例如静电能来致动开关。

56. 发明申请

US20070260287A1 CHIP LEVEL BIOSTABLE INTERCONNECT FOR IMPLANTABLE MEDICAL DEVICES 有权
标题翻译：用于可植入医疗器械的芯片级可生物互连
公开(公告)号：US20070260287A1
公开(公告)日：2007-11-08
申请号：US11735832
申请日：2007-04-16
申请人： Rogier Receveur
发明人： Rogier Receveur
IPC分类号： A61N1/00
CPC分类号： A61N1/3754 , H01L2924/00013 , Y10S439/909 , H01L2224/13099 , H01L2224/13599 , H01L2224/05599 , H01L2224/05099 , H01L2224/29099 , H01L2224/29599
摘要： A lead is connected to an integrated circuit in an implantable medical device in a lead bonding area that includes a lead-receiving recessed region. At least a portion of a lead conductor is bonded in the lead-receiving recessed region, making an electrical and mechanical connection to the integrated circuit that is strong and potentially biostable. In some embodiments, a filler material is provided around the recessed portion of the integrated circuit that receives the lead conductor, and a metal coating is provided around an outer surface of the filler material for additional mechanical stability.
摘要翻译：引线与包括引线接收凹入区域的引线接合区域中的可植入医疗器件中的集成电路连接。引线导体的至少一部分结合在引线接收凹入区域中，使得与集成电路的电连接和机械连接是强的并且具有潜在的生物稳定性。在一些实施例中，填充材料设置在集成电路的凹陷部分周围，该集成电路的凹部接收引线导体，并且在填充材料的外表面周围设置金属涂层以用于额外的机械稳定性。

57. 发明申请

US20060241731A1 Chip level biostable interconnect for implantable medical devices 有权
标题翻译：用于可植入医疗器械的芯片级生物稳定互连
公开(公告)号：US20060241731A1
公开(公告)日：2006-10-26
申请号：US11114451
申请日：2005-04-26
申请人： Rogier Receveur
发明人： Rogier Receveur
IPC分类号： A61N1/05
CPC分类号： A61N1/3754 , H01L2924/00013 , Y10S439/909 , H01L2224/13099 , H01L2224/13599 , H01L2224/05599 , H01L2224/05099 , H01L2224/29099 , H01L2224/29599
摘要： A lead is connected to an integrated circuit in an implantable medical device in a lead bonding region that includes a lead-receiving recessed region. At least a portion of a lead conductor is bonded in the lead-receiving recessed region, making an electrical and mechanical connection to the integrated circuit that is strong and potentially biostable. In some embodiments, a filler material is provided around the recessed portion of the integrated circuit that receives the lead conductor, and a metal coating is provided around an outer surface of the filler material for additional mechanical stability.
摘要翻译：引线连接到包括引线接收凹入区域的引线接合区域中的可植入医疗器件中的集成电路。引线导体的至少一部分结合在引线接收凹入区域中，使得与集成电路的电连接和机械连接是强的并且具有潜在的生物稳定性。在一些实施例中，填充材料设置在集成电路的凹陷部分周围，该集成电路的凹部接收引线导体，并且在填充材料的外表面周围设置金属涂层以用于额外的机械稳定性。

58. 发明申请

US20060192272A1 Wafer level hermetically sealed MEMS device 有权
标题翻译：晶圆级气密密封的MEMS器件
公开(公告)号：US20060192272A1
公开(公告)日：2006-08-31
申请号：US11066820
申请日：2005-02-25
申请人： Rogier Receveur , Cornel Marxer
发明人： Rogier Receveur , Cornel Marxer
IPC分类号： H01L23/58
CPC分类号： B81C1/0023 , B81B7/007 , B81C2203/0109 , Y10T29/49105
摘要： A hermetically sealed microelectromechanical system (MEMS) package includes a MEMS switch having a movable portion and a stationary portion with an electrical contact thereon. A glass lid is anodically bonded to the MEMS switch to form a sealed cavity over the movable portion of the MEMS switch. The glass lid includes a contact aperture to allow access to the electrical contact on the stationary portion of the MEMS switch. A family of body-implantable hermetically-sealed MEMS packages are provided according to certain aspects and embodiments of the present invention.
摘要翻译：密封的微机电系统（MEMS）封装包括具有可移动部分的MEMS开关和在其上具有电接触的固定部分。玻璃盖阳极结合到MEMS开关，以在MEMS开关的可移动部分上形成密封空腔。玻璃盖包括接触孔，以允许接近MEMS开关的固定部分上的电接触。根据本发明的某些方面和实施例提供了一系列可植入人体的气密密封的MEMS封装。

59. 发明申请

US20050115811A1 MEMs switching circuit and method for an implantable medical device 有权
标题翻译：用于可植入医疗装置的MEMs切换电路和方法
公开(公告)号：US20050115811A1
公开(公告)日：2005-06-02
申请号：US10973117
申请日：2004-10-26
申请人： Rogier Receveur , Cornel Marxer
发明人： Rogier Receveur , Cornel Marxer
IPC分类号： A61N1/00 , A61N1/37 , A61N1/39 , H01H59/00
CPC分类号： H01H59/0009 , A61N1/37 , A61N1/3912 , H01H2001/0042
摘要： A bistable MEMS switch for use in selectively opening or closing electrical circuits included in an implantable medical device system is provided. The switch includes a central movable beam having a movable contact; a suspension system for supporting the movable beam and generating a contact force; an actuator for displacing the beam upon application of an activation signal, and a fixed contact for interfacing the movable contact when the switch is in a closed state. The switch is fabricated from a Si/SiO2/Si wafer using photolithography, DRIE and sacrificial oxide etching followed by metalization of electrical contact points with a wear-resistant metal or alloy. An actuation layer may be fabricated from the silicon substrate layer of the wafer and the signal layer may be fabricated from the top silicon layer. The actuation layer and signal layer are thereby electrically decoupled and mechanically coupled by the intervening SiO2 layer.
摘要翻译：提供了一种用于选择性地打开或关闭包括在可植入医疗装置系统中的电路的双稳态MEMS开关。开关包括具有可移动触点的中心可动梁; 用于支撑可移动梁并产生接触力的悬架系统; 用于在施加激活信号时移动所述光束的致动器，以及用于当所述开关处于闭合状态时将所述可动触头对接的固定触点。使用光刻，DRIE和牺牲氧化物蚀刻由Si / SiO 2 / Si / Si晶片制造开关，随后用耐磨金属或合金金属化电接触点。可以从晶片的硅衬底层制造致动层，并且可以从顶部硅层制造信号层。因此，致动层和信号层通过介入的SiO 2层进行电去耦和机械耦合。

60. 发明申请

US20110160790A1 MEASUREMENT OF CORONARY SINUS PARAMETERS TO OPTIMIZE LEFT VENTRICULAR PERFORMANCE 审中-公开
标题翻译：冠状动脉参数的测量优化左心室性能
公开(公告)号：US20110160790A1
公开(公告)日：2011-06-30
申请号：US13042800
申请日：2011-03-08
申请人： Berthold Stegemann , Rogier Receveur
发明人： Berthold Stegemann , Rogier Receveur
IPC分类号： A61N1/365
CPC分类号： A61N1/36585 , A61B5/14532 , A61N1/3627 , A61N1/3655 , A61N1/36557 , A61N1/36571
摘要： In some embodiments, an implantable medical device (IMD) system may include one or more of the following elements: (a) an oxygen sensor for measuring oxygen extraction from blood flowing through a coronary sinus of a patient's heart, (b) an oxygen signal generated by the oxygen sensor, (c) an IMD coupled to the oxygen sensor, wherein the IMD is configured to output pacing pulses as a function of the oxygen signal, and (d) an atrial and a ventricular pacing lead coupled to the IMD to deliver the pacing pulses to the patient's heart, wherein the IMD generates the pacing pulses as a function of the oxygen signal, wherein the pacing pulses are adjusted by the IMD as a function of the oxygen signal, wherein the IMD is configured to adjust the pacing pulses to increase oxygen in the blood flow through the coronary sinus.
摘要翻译：在一些实施例中，可植入医疗装置（IMD）系统可以包括以下元件中的一个或多个：（a）氧传感器，用于测量从流过患者心脏的冠状窦的血液中提取氧气，（b）氧信号由氧传感器产生的，（c）耦合到所述氧传感器的IMD，其中所述IMD被配置为输出作为所述氧信号的函数的起搏脉冲，以及（d）心房和心室起搏线，其耦合到所述IMD至将起搏脉冲递送到患者的心脏，其中IMD根据氧信号产生起搏脉冲，其中起搏脉冲作为氧信号的函数由IMD调节，其中IMD被配置为调整起搏脉冲以增加通过冠状窦的血液中的氧气。

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