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51. 发明申请

US20050010131A1 Breast biopsy system and methods 审中-公开
公开(公告)号：US20050010131A1
公开(公告)日：2005-01-13
申请号：US10913747
申请日：2004-08-06
申请人： Fred Burbank , Michael Jones , Paul Lubock
发明人： Fred Burbank , Michael Jones , Paul Lubock
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： An apparatus and method are provided for precisely isolating a target lesion in a patient's body tissue, resulting in a high likelihood of “clean” margins about the lesion when it is removed for diagnosis and/or therapy. This approach advantageously will often result in the ability to both diagnose and treat a malignant lesion with only a single percutaneous procedure, with no follow-up percutaneous or surgical procedure required, while minimizing the risk of migration of possibly cancerous cells from the lesion to surrounding tissue or the bloodstream. In particular, the apparatus comprises a biopsy instrument having a distal end adapted for entry into the patient's body, a longitudinal shaft, and a cutting element disposed along the shaft. The cutting element is actuatable between a radially retracted position and a radially extended position. Advantageously, the instrument is rotatable about its axis in the radially extended position to isolate a desired tissue specimen from surrounding tissue by defining a peripheral margin about the tissue specimen. Once the tissue specimen is isolated, it may be segmented by further manipulation of the cutting element, after which the tissue segments are preferably individually removed from the patient's body through a cannula or the like. Alternatively, the specimen may be encapsulated and removed as an intact piece.

52. 发明授权

US09017273B2 Devices and methods for treating restless leg syndrome 有权
标题翻译：用于治疗不宁腿综合征的装置和方法
公开(公告)号：US09017273B2
公开(公告)日：2015-04-28
申请号：US12396358
申请日：2009-03-02
申请人： Fred Burbank , Mike Jones , Al Memmolo
发明人： Fred Burbank , Mike Jones , Al Memmolo
IPC分类号： A61H23/00 , A61H1/02 , A61H1/00 , A61H7/00 , A61H9/00 , A61H15/00 , A61H23/02 , A61N1/36 , A61F7/00 , A61F7/02 , A61N2/00
CPC分类号： A61H23/02 , A61F2007/0071 , A61F2007/0075 , A61F2007/0296 , A61H1/008 , A61H1/0237 , A61H1/0255 , A61H1/0266 , A61H7/001 , A61H7/004 , A61H9/0078 , A61H9/0092 , A61H15/0078 , A61H23/0218 , A61H23/0263 , A61H2015/0014 , A61H2201/0142 , A61H2201/02 , A61H2201/0228 , A61H2201/0242 , A61H2201/0257 , A61H2201/0285 , A61H2201/10 , A61H2201/105 , A61H2201/1207 , A61H2201/1215 , A61H2201/1642 , A61H2201/165 , A61H2201/1676 , A61H2201/5005 , A61H2203/0456 , A61H2205/10 , A61H2205/106 , A61H2205/108 , A61H2205/12 , A61N1/36021 , A61N2/00
摘要： An exemplary system for generating a counter-stimulation in a patient suffering from RLS includes a device configured and arranged to generate a counter-stimulation in a patient suffering from RLS, the counter-stimulation of an amplitude, intensity, and time duration lower than that which would wake the patient and higher than that sufficient to relieve RLS, or sufficient to relieve RLS symptoms and allow the patient to return to sleep, a controller configured and arranged to drive the counter-stimulation generation device, the controller being in communication with the counter-stimulation device, and a base configured and arranged to hold the counter-stimulation generation device adjacent to a patient, the counter-stimulation device attached to the base. An exemplary method of treating RLS includes selecting a patient experiencing RLS, and stimulating a portion of the patient at an amplitude, intensity, and duration sufficient to act as a counter-stimulation to RLS.
摘要翻译：用于在患有RLS的患者中产生反刺激的示例性系统包括配置和布置成在患有RLS的患者中产生反刺激的装置，对抗RLS的患者的反搏刺激，幅度，强度和持续时间低于其将唤醒患者并且高于足以减轻RLS的量，或者足以减轻RLS症状并允许患者返回睡眠的控制器，被配置和布置成驱动反刺激产生装置的控制器与控制器通信反刺激装置，以及被配置和布置为将反刺激产生装置保持在与患者相邻的基部，所述反刺激装置附接到所述基部。治疗RLS的示例性方法包括选择经历RLS的患者，并以足以用作对RLS的反刺激的幅度，强度和持续时间刺激患者的一部分。

53. 发明申请

US20080097473A1 Treatment for post partum hemorrhage 审中-公开
标题翻译：治疗产后出血
公开(公告)号：US20080097473A1
公开(公告)日：2008-04-24
申请号：US11881981
申请日：2007-07-30
申请人： Fred Burbank , Michael Jones , Jill Uyeno
发明人： Fred Burbank , Michael Jones , Jill Uyeno
IPC分类号： A61B17/42
CPC分类号： A61B17/12 , A61B17/2812 , A61B17/42 , A61B2017/00057 , A61B2017/2837 , A61B2090/064 , A61B2090/378
摘要： The invention is directed to instruments and procedures using such instruments for temporarily reducing or terminating blood flow through a female patient's uterine artery to treat post partum hemorrhage (PPH). The uterine artery is occluded by a clamping device which includes a pair of pivotally connected clamping members, with each of the clamping members having a handle and a clamping element at the distal end of the handle. The clamping elements are inclined with respect to the longitudinal axes of the handles at an included obtuse angle between about 120° and about 170°, preferably between about 130° and 160°. An artery locating sensor is provided on the distal end of at least one of the clamping elements. Preferably, the artery locating sensor is a Doppler ultrasound blood flow sensor. After birth, the clamping device is inserted into the female patient's post partum vaginal canal and advanced therein until one of the clamping elements Is in the patient's uterine cervix and the other clamping element is on the exterior of the uterine cervix. The clamping element on the exterior of the patient's uterine cervix is pressed against the patient's vaginal fornix and the clamping device closed so as to occlude the uterine artery disposed within tissue grasped by the clamping device. The clamping device is locked in the closed configuration and maintained in the condition until the patient's uterus is sufficiently clotted up to ensure termination of the hemorrhaging, typically about 5 minutes to about 7 hours.
摘要翻译：本发明涉及使用这种器械临时减少或终止通过女性患者子宫动脉的血液流动以治疗产后出血（PPH）的仪器和程序。子宫动脉被包括一对枢转连接的夹紧构件的夹紧装置封闭，其中每个夹紧构件具有手柄和在手柄的远端处的夹紧元件。夹紧元件相对于把手的纵向轴线以约120°至约170°之间，优选地在约130°至160°之间的包含的钝角倾斜。动脉定位传感器设置在至少一个夹紧元件的远端上。优选地，动脉定位传感器是多普勒超声血流传感器。出生后，将夹紧装置插入雌性患者的产后阴道管中并推进到其中，直到其中一个夹紧元件位于患者的子宫颈中，而另一个夹紧元件位于子宫颈的外部。患者子宫颈外侧的夹紧元件被压靠在患者的阴道穹窿上，并且夹紧装置关闭，从而封闭设置在由夹紧装置抓握的组织内的子宫动脉。夹紧装置被锁定在闭合构型中并保持在状态，直到患者的子宫充分凝结，以确保终止出血，通常约5分钟至约7小时。

54. 发明申请

US20080077045A1 Tissue specimen encapsulation device and method thereof 有权
标题翻译：组织标本包封装置及其方法
公开(公告)号：US20080077045A1
公开(公告)日：2008-03-27
申请号：US11811952
申请日：2007-06-12
申请人： Fred Burbank , Richard Quick , Jacob Louw , Michael Jones , Paul Lubock
发明人： Fred Burbank , Richard Quick , Jacob Louw , Michael Jones , Paul Lubock
IPC分类号： A61B10/02
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00234 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2017/00287 , A61B2017/2212 , A61B2017/320064 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for encapsulating tissue specimens includes a wand assembly, a sheath, and a guide assembly. The guide assembly pulls, draws, or otherwise moves the sheath about the tissue specimen. The wand assembly is disposed proximate to the tissue specimen, typically either adjacent or through the specimen. In an aspect of the encapsulating device, the guide assembly has sheath deployment members that are disposed about the tissue specimen. The sheath, which is attached to ends of the sheath deployment members and the wand assembly, is drawn over the tissue specimen as the sheath deployment members are pushed or pulled. The guide assembly is an arm or a housing that rotates about the tissue specimen. The sheath, which is secured at one end to the guide assembly and at another end to the wand assembly, is drawn over the tissue specimen as the guide assembly rotates.
摘要翻译：用于封装组织样本的装置包括棒组件，护套和引导组件。引导组件拉动，牵引或以其他方式使护套围绕组织标本移动。棒组件靠近组织标本设置，通常是相邻的或通过样本。在封装装置的一个方面中，引导组件具有围绕组织标本设置的护套展开部件。当护套展开构件被推动或拉动时，附接到鞘展开构件和杆组件的端部的护套被拉过组织标本。引导组件是围绕组织标本旋转的臂或壳体。当引导组件旋转时，在一端固定到引导组件并且另一端固定到杆组件的护套在组织样本上被拉伸。

55. 发明申请

US20070232955A1 Apparatus and method for accessing a body site 有权
公开(公告)号：US20070232955A1
公开(公告)日：2007-10-04
申请号：US11807293
申请日：2007-05-25
申请人： Fred Burbank , Paul Lubock , Martin Shabaz , Frank Louw
发明人： Fred Burbank , Paul Lubock , Martin Shabaz , Frank Louw
IPC分类号： A61B10/02 , A61B18/14
CPC分类号： A61B10/0266 , A61B10/02 , A61B10/0275 , A61B10/0283 , A61B10/04 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2010/0208 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00291 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1412 , A61B2018/1425 , A61B2018/1455 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device and method of using the device to access a desired tissue site within a patient's body and separating a tissue specimen from the tissue site suitable for evaluation. The device includes a probe member having an arcuate tissue-cutting RF powered electrode secured to and distally spaced from the distal end of the probe and a small dimensioned distal extremity which when an inner lumen thereof is subjected to a vacuum, secured tissue for the specimen to the surface of the distal extremity. A circular tissue-cutting blade preferably secured to the distal end of a supporting tube is configured to rotate and move longitudinally along the shaft of the probe member effective to sever a tissue specimen from tissue secured to the surface of the distal extremity of the probe member. The supporting tube covers the separated specimen, and may be disposed within an accessing cannula.

56. 发明申请

US20070049973A1 Method and device for treating adenomyosis and endometriosis 审中-公开
标题翻译：治疗子宫腺肌症和子宫内膜异位症的方法和装置
公开(公告)号：US20070049973A1
公开(公告)日：2007-03-01
申请号：US11214606
申请日：2005-08-29
申请人： Fred Burbank , Michael Jones , R. Serra , Greig Altieri , Jill Uyeno , Yu-Tung Wong , Randy Werneth
发明人： Fred Burbank , Michael Jones , R. Serra , Greig Altieri , Jill Uyeno , Yu-Tung Wong , Randy Werneth
IPC分类号： A61N1/00
CPC分类号： A61B17/2812 , A61B5/026 , A61B8/06 , A61B8/12 , A61B17/122 , A61B17/282 , A61B17/2833 , A61B17/42 , A61B2017/00106 , A61B2017/2808 , A61B2017/4216
摘要： The invention provides devices, systems and methods for reducing or abolishing blood flow by occluding uterine arteries for treating adenomyosis and endometriosis. A non-invasive uterine artery occlusion device embodying features of the invention includes a pair of pressure-applying members with opposed tissue-contacting surfaces, a supporting shaft configured to adjust the distance between tissue-contacting surfaces, and at least one sensor for locating a uterine artery disposed on at least one pressure-applying member. Uterine arteries are occluded by indirectly compressing the artery by compressing tissue near to an artery. One uterine artery may be occluded or both may be occluded simultaneously. A uterine artery may be accessed via a body cavity, such as a patient's vagina, and may be occluded by compressing a portion of the vaginal wall around a portion of a uterine artery.
摘要翻译：本发明提供了用于通过闭塞子宫动脉来治疗子宫腺肌症和子宫内膜异位症来减少或消除血流的装置，系统和方法。体现本发明特征的非侵入性子宫动脉阻塞装置包括一对具有相对的组织接触表面的压力施加构件，配置成调节组织接触表面之间的距离的支撑轴和至少一个用于定位子宫动脉设置在至少一个压力施加构件上。通过压迫动脉附近的组织间接压迫动脉来闭塞子宫动脉。一个子宫动脉可能被闭塞，或两者可能同时闭塞。子宫动脉可以通过体腔（例如患者的阴道）进入，并且可以通过在子宫动脉的一部分周围压缩阴道壁的一部分来封闭子宫动脉。

57. 发明申请

US20060167377A1 Methods and devices for automated biopsy and collection of soft tissue 审中-公开
公开(公告)号：US20060167377A1
公开(公告)日：2006-07-27
申请号：US11388453
申请日：2006-03-24
申请人： Mark Ritchart , J. Stuart , Fred Burbank , Kenneth Galt
发明人： Mark Ritchart , J. Stuart , Fred Burbank , Kenneth Galt
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B6/12 , A61B8/0841 , A61B10/0275 , A61B10/0283 , A61B17/221 , A61B2010/0208 , A61B2010/0225 , A61B2017/303
摘要： Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.

58. 发明申请

US20060122503A1 Imageable biopsy site marker 审中-公开
公开(公告)号：US20060122503A1
公开(公告)日：2006-06-08
申请号：US11342011
申请日：2006-01-27
申请人： Fred Burbank , Paul Lubock , Michael Jones , Nancy Forcier
发明人： Fred Burbank , Paul Lubock , Michael Jones , Nancy Forcier
IPC分类号： A61B6/00
CPC分类号： A61B90/39 , A61B10/02 , A61B2017/00004 , A61B2090/3788 , A61B2090/3908 , A61B2090/3925 , A61B2090/3929 , A61B2090/3933 , A61B2090/395 , A61B2090/3975 , A61B2090/3987 , A61B2090/3995 , A61K49/006 , A61M37/0069
摘要： A biopsy site marker having at least one small marker body or pellet of bioresorbable material such as gelatin, collagen, polylactic acid, polyglycolic acid which has a radiopaque object, preferably with a non-biological configuration. The at least one bioresorbable body or pellet with a radiopaque object is deposited into the biopsy site, by an delivery device that includes an elongated tubular body with a piston slidable within the tubular body. One end of the tube is placed into the biopsy site. At least one but preferably several marker bodies or pellets are deposited sequentially into the biopsy site through the tube. At least the bioresorbable materials of the detectable markers remain present in sufficient quantity to permit detection and location of the biopsy site at a first time point (e.g., 2 weeks) after introduction but clear from the biopsy site or otherwise do not interfere with imaging of tissues adjacent the biopsy site at a second time point (e.g., 5-7 months) after introduction.

59. 发明申请

US20060036165A1 Tissue site markers for in vivo imaging 有权
公开(公告)号：US20060036165A1
公开(公告)日：2006-02-16
申请号：US11238201
申请日：2005-09-29
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick , Frank Louw , Stephen De Santis
IPC分类号： A61B6/00
CPC分类号： A61M37/0069 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B90/39 , A61B2017/00004 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/006 , A61K49/222
摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

60. 发明申请

US20050245842A1 Methods and apparatus for securing medical instruments to desired locations in a patient's body 有权
标题翻译：将医疗器械固定在患者身体所需位置的方法和装置
公开(公告)号：US20050245842A1
公开(公告)日：2005-11-03
申请号：US11179277
申请日：2005-07-11
申请人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
发明人： Fred Burbank , Paul Lubock , Michael Jones , Richard Quick
IPC分类号： A61B10/02 , A61B10/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/12 , A61B18/14 , A61B19/00 , A61F2/82
CPC分类号： A61B10/04 , A61B10/02 , A61B10/0241 , A61B10/0266 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/12 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/320064 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2019/5487 , A61B2019/5491 , A61B2090/3908 , A61B2090/3991
摘要： Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.
摘要翻译：提供了设备和方法，用于使用固定剂将医疗器械牢固地固定在患者体内的期望的组织上。这样的医疗器械可以包括定位线或组织采集器械，例如活检器械。在组织采集仪器的情况下，本发明人已经发现了将组织采集仪器的远端牢固地固定到特定组织靶区域的显着优点。例如，这种方法允许成像环境与程序环境分离，从而不需要使用诸如立体定向成像设备之类的昂贵和经常不可用的成像设备。在优选的实施方案中，使用粘合剂，例如粘合剂，手术胶或溶剂作为固定剂。

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