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51. 发明授权

US5224037A Design of super-fast three-dimensional projection system for Positron Emission Tomography 失效
标题翻译：用于正电子发射断层扫描的超快三维投影系统的设计
公开(公告)号：US5224037A
公开(公告)日：1993-06-29
申请号：US670291
申请日：1991-03-15
申请人： William F. Jones , Michael E. Casey , Larry G. Byars
发明人： William F. Jones , Michael E. Casey , Larry G. Byars
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/421 , G06T2211/428
摘要： A 3-dimensional projection system (10) for the rapid back projection of multi-ring Positron Emission Tomography (PET) scan data composed of planes (44) of two-dimensional data defining individual Lines Of Response (LOR) (42) into a plurality of image voxels for three-dimensional display on a video screen. The projection system (10) of the preferred embodiment is a Very Large Scale Integration (VLSI) based architecture which will support forward and back projection for a 3-dimensional image detected by a multi-ring PET scanner. A selected number of processing engines (20) are included for forward projection and back projection, the number of engines (20) being inversely proportional to the projection time.
摘要翻译：一种用于快速反投影多环正射子断层扫描（PET）扫描数据的三维投影系统（10），该扫描数据由定义各个响应线（LOR）（42）的二维数据的平面（44）组成一个用于在视频屏幕上进行三维显示的多个图像体素。优选实施例的投影系统（10）是基于超大规模集成（VLSI）的架构，其将支持由多环PET扫描器检测到的三维图像的向前和向后投影。所选数量的处理引擎（20）被包括用于向前投影和反投影，发动机（20）的数量与投影时间成反比。

52. 发明授权

US4750972A Process for fabricating tuned light guide for photoelectrons 失效
标题翻译：制造光电子调谐光导的工艺
公开(公告)号：US4750972A
公开(公告)日：1988-06-14
申请号：US39916
申请日：1987-04-20
申请人： Michael E. Casey , Ronald Nutt , Terry D. Douglass
发明人： Michael E. Casey , Ronald Nutt , Terry D. Douglass
IPC分类号： G01T1/202 , G01T1/29 , H01L21/306 , B44C1/22 , C03C15/00 , C03C25/06
CPC分类号： G01T1/202 , G01T1/2985
摘要： A two dimensional photon position encoder system (10) and process which includes a detector (20) for enhancing the spatial resolution of the situs of the origin of incident photons of gamma rays. A plurality of scintillator material members (22) interact with the incident photons and produce a quantifiable number of photons which exit the scintillation material members. A tuned light guide (68) having a plurality of radiation barriers (92) of predetermined lengths define slots which are operatively associated with one of the scintillator material members. Photons exiting the scintillator material members (22) enter an operatively associated slot in said slotted light guide. These slots (90) serve to enhance the predictability of the statistical distribution of photons along the length of the slotted light guide (68). A detector (20) detects the distribution of the photons at preselected locations along the length of the slotted light guide. In one embodiment, this detector (20) comprises a photomultiplier (70) which gathers information concerning the photoelectrons which are then counted. The statistical distribution of these photoelectrons is processed by an improved pattern recognition technique such that the positioning information can be determined.
摘要翻译：一种二维光子位置编码器系统（10），其包括用于增强伽马射线入射光子原点的位置的空间分辨率的检测器（20）的处理。多个闪烁体材料构件（22）与入射的光子相互作用并产生可从数量上闪烁的材料构件的数量的光子。具有多个具有预定长度的辐射屏障（92）的调谐光导（68）限定与闪烁体材料构件之一可操作地相关的槽。离开闪烁体材料构件（22）的光子进入所述开槽光导中的可操作地关联的狭槽。这些槽（90）用于增强沿着带槽光导（68）的长度的光子的统计分布的可预测性。检测器（20）沿着狭缝光导的长度检测预选位置处的光子的分布。在一个实施例中，该检测器（20）包括光电倍增器（70），其收集关于光电子的信息，然后对其进行计数。这些光电子的统计分布通过改进的模式识别技术来处理，使得可以确定定位信息。

53. 发明授权

US4743764A Two dimensional photon counting position encoder system and process 失效
标题翻译：二维光子计数位置编码器系统及过程
公开(公告)号：US4743764A
公开(公告)日：1988-05-10
申请号：US677931
申请日：1984-12-04
申请人： Michael E. Casey , Ronald Nutt , Terry D. Douglas
发明人： Michael E. Casey , Ronald Nutt , Terry D. Douglas
IPC分类号： G01T1/202 , G01T1/29 , G01T1/20
CPC分类号： G01T1/202 , G01T1/2985
摘要： A two dimensional photon position encoder system (10) and process which includes a detector (20) for enhancing the spatial resolution of the situs of the origin of incident photons of gamma rays. A plurality of scintillator material members (22) interact with the incident photons and produce a quantifiable number of photons which exit the scintillation material members. A tuned light guide (68) having a plurality of radiation barriers (92) of predetermined lengths define slots which are operatively associated with one of the scintillator material members. Photons exiting the scintillator material members (22) enter an operatively associated slot in said slotted light guide. These slots (90) serve to enhance the predictability of the statistical distribution of photons along the length of the slotted light guide (68). A detector (20) detects the distribution of the photons at preselected locations along the length of the slotted light guide. In one embodiment, this detector (20) comprises a photomultiplier (70) which gathers information concerning the photoelectrons which are then counted. The statistical distribution of these photoelectrons is processed by an improved pattern recognition technique such that the positioning information can be determined.
摘要翻译：一种二维光子位置编码器系统（10），其包括用于增强伽马射线入射光子原点的位置的空间分辨率的检测器（20）的处理。多个闪烁体材料构件（22）与入射的光子相互作用并产生可从数量上闪烁的材料构件的数量的光子。具有多个具有预定长度的辐射屏障（92）的调谐光导（68）限定与闪烁体材料构件之一可操作地相关的槽。离开闪烁体材料构件（22）的光子进入所述开槽光导中的可操作地关联的狭槽。这些槽（90）用于增强沿着带槽光导（68）的长度的光子的统计分布的可预测性。检测器（20）沿着狭缝光导的长度检测预选位置处的光子的分布。在一个实施例中，该检测器（20）包括光电倍增器（70），其收集关于光电子的信息，然后对其进行计数。这些光电子的统计分布通过改进的模式识别技术来处理，使得可以确定定位信息。

54. 发明授权

US09645261B2 Normalization coefficients in PET continuous bed motion acquisition 有权
公开(公告)号：US09645261B2
公开(公告)日：2017-05-09
申请号：US13739458
申请日：2013-01-11
申请人： Vladimir Y. Panin , Michael E. Casey
发明人： Vladimir Y. Panin , Michael E. Casey
IPC分类号： G01T1/29 , A61B6/03
CPC分类号： G01T1/2985 , A61B6/037
摘要： Normalization coefficients in are computed for positron emission tomography (PET) continuous bed motion acquisition (CBM). The normalization coefficients for the lines-of-response in CBM account for the change in decay of the injected isotope over time and/or changes in velocity of the bed motion.

55. 发明授权

US08509504B2 Point spread function radial component implementation in Joseph's forward projector 有权
标题翻译：约瑟夫向前投影机的点扩散功能径向元件实现
公开(公告)号：US08509504B2
公开(公告)日：2013-08-13
申请号：US12561139
申请日：2009-09-16
申请人： Michael E. Casey , Vladimir Y. Panin
发明人： Michael E. Casey , Vladimir Y. Panin
IPC分类号： G06K9/00 , G06K9/62
CPC分类号： G06T11/006 , G06T2211/424
摘要： Point spread function (PSF) radial filtering in a line of response space. Modeling a radial component, R, of a point spread filter as a function of at least a radial projection index ρ, a radial image space coordinate r, and an azimuth θ. The index ρ is characterized by an asymmetrical Gaussian distribution having where σleft(r) and σright(r) derived from point source measurements, and an adjustment σJ(r, θ) estimated from point source sinogram by Josephs' projector.
摘要翻译：点扩散函数（PSF）径向滤波在一行响应空间。将点扩展滤波器的径向分量R作为至少径向投影指数rho，径向图像空间坐标r和方位角θ的函数建模。索引rho的特征在于具有不对称高斯分布，其中从点源测量得到sigmaleft（r）和sigmaright（r），以及通过Josephs投影仪从点源正弦图估计的调节σJ（r，θ）。

56. 发明授权

US08170855B2 System for simulating PET gantry 有权
标题翻译：用于模拟PET龙门架的系统
公开(公告)号：US08170855B2
公开(公告)日：2012-05-01
申请号：US12110485
申请日：2008-04-28
申请人： William Jones , John E. Breeding , Johnny H. Reed , Jimmy Everman , Michael E. Casey
发明人： William Jones , John E. Breeding , Johnny H. Reed , Jimmy Everman , Michael E. Casey
IPC分类号： G06F17/50
CPC分类号： G06F11/261
摘要： A system for simulating a Positron Emission Tomography (PET) gantry has a computer system having a bus system for receiving expansion cards, a mass data storage support system, the mass storage system being operable to store coincidence-event and tag packet data, and a data transfer simulation card for said bus system, wherein the data transfer simulation card is operable to simulate transfer timing of the stored coincidence-event and tag packet data.
摘要翻译：用于模拟正电子发射断层扫描（PET）龙门架的系统具有计算机系统，其具有用于接收扩展卡的总线系统，大容量数据存储支持系统，大容量存储系统可操作以存储符合事件和标签分组数据，以及用于所述总线系统的数据传输模拟卡，其中数据传输模拟卡可操作以模拟存储的符合事件和标签分组数据的传送定时。

57. 发明授权

US07949172B2 Iterative image processing 失效
标题翻译：迭代图像处理
公开(公告)号：US07949172B2
公开(公告)日：2011-05-24
申请号：US11771197
申请日：2007-06-29
申请人： Maurizio Conti , Michael E. Casey
发明人： Maurizio Conti , Michael E. Casey
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/424
摘要： A method for processing an image which has the steps of a) receiving acquired data necessary to obtain an image and estimating a preliminary image; b) selecting at least one image element within the image; c) performing an iterative algorithm for processing the image at least on the at least one image element; d) computing a difference between the processed at least one image element and the at least one image element; and e) repeating the steps c) and d) until the difference is below a predefined threshold.
摘要翻译：一种用于处理图像的方法，该方法具有以下步骤：a）接收获取图像所需的获得的数据并估计初步图像; b）选择图像内的至少一个图像元素; c）执行至少在所述至少一个图像元素处理所述图像的迭代算法; d）计算所处理的至少一个图像元素与所述至少一个图像元素之间的差异; 和e）重复步骤c）和d），直到该差值低于预定阈值。

58. 发明申请

US20100076300A1 DATA PROCESSING SYSTEM FOR MULTI-MODALITY IMAGING 有权
标题翻译：用于多模式成像的数据处理系统
公开(公告)号：US20100076300A1
公开(公告)日：2010-03-25
申请号：US12564635
申请日：2009-09-22
申请人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
发明人： Roger E. Arseneau , James Frank Caruba , Michael E. Casey , Mark Musrock , Nan Zhang
IPC分类号： A61B5/055
CPC分类号： G01T1/1603 , A61B6/037 , A61B6/5247
摘要： A data processing process and embodiment for optimizing the signal path for multi-modality imaging is described. The embodiment and process optimizes the signal to noise ratio in a positron emission tomography (PET) signal path utilizing scintillation crystals, avalanche photo diodes, and charge sensitive preamplifiers in a dual modality MRI/PET scanner. The dual use of both and analog pole zero circuit and a digital filter enables higher signal levels or a fixed ADC input range and thus a higher possible signal to noise ratio in the presence of significant pileup caused by high positron activity. The higher signal to noise ratio is needed in the PET signal architecture, because of the presence of non-modal time varying electromagnetic fields from the MR, which are a significant source of noise for the wideband PET signal modality.
摘要翻译：描述了用于优化用于多模态成像的信号路径的数据处理过程和实施例。实施例和过程利用双重模式MRI / PET扫描器中的闪烁晶体，雪崩光电二极管和电荷敏感前置放大器在正电子发射断层摄影（PET）信号路径中优化信噪比。双重使用模拟极零电路和数字滤波器可实现更高的信号电平或固定的ADC输入范围，从而在存在由高正电子活动引起的重大堆积的情况下，可能的信噪比更高。在PET信号架构中需要更高的信噪比，因为存在来自MR的非模态时变电磁场，这是对于宽带PET信号模态的噪声的重要来源。

59. 发明申请

US20100061263A1 DEFINING LOST EVENT TALLEY TAG PACKETS WHEN PET COUNT RATES EXCEED AVAILABLE ACQUISITION BANDWIDTH 有权
标题翻译：当PET计数超过可用的获取带宽时，定义丢失的事件TALLEY TAG PACKETS
公开(公告)号：US20100061263A1
公开(公告)日：2010-03-11
申请号：US12558055
申请日：2009-09-11
申请人： John E. Breeding , Michael E. Casey , Jimmy Everman , William F. Jones , Johhny H. Reed , Wing K. Luk
发明人： John E. Breeding , Michael E. Casey , Jimmy Everman , William F. Jones , Johhny H. Reed , Wing K. Luk
IPC分类号： H04L12/26
CPC分类号： G01T1/00 , H04L67/12 , H04L69/40
摘要： A system identifies when received packets are lost at a node in a multi-node processing chain. The system processing chain may include a gantry interface module for receiving coincident event data from a PET (Positron Emission Tomography) detector array, a DMA (direct memory access) rebinner card, and a transmission line coupled between the gantry interface module and the DMA card. FPGA and FIFO elements in each processing portion receive packets that may be lost if there is insufficient FIFO capacity. Lost packets are marked, discarded, and counted. At specified intervals, set in accordance with a threshold number of packets received a lost tally data packet is generated that includes count information for lost packets. The lost tally data packet is forwarded downstream when sufficient storage capacity exists.
摘要翻译：系统识别在多节点处理链中的节点处收到的数据包丢失的情况。系统处理链可以包括用于从PET（正电子发射断层扫描）检测器阵列，DMA（直接存储器访问）重新接收器卡和耦合在台架接口模块和DMA卡之间的传输线接收重合事件数据的龙门架接口模块。每个处理部分的FPGA和FIFO元素接收到如果FIFO容量不足可能会丢失的数据包。丢失的数据包被标记，丢弃和计数。按指定间隔设置，根据接收到的丢包数据包的阈值数量，生成包括丢失数据包的计数信息。当存在足够的存储容量时，丢失的计数数据分组被转发到下游。

60. 发明授权

US07638771B2 On-line time-of-flight mashing: DMA rebinning applied to a long-axis PET-TOF system for reduced transaxial angular sampling with 3-D nearest-neighbor projection-space rebinning in clinical PET/CT 有权
标题翻译：在线时间飞行糖化：DMA重组应用于长轴PET-TOF系统，用于在临床PET / CT中具有3维最近邻投影空间重组的减少横轴角度采样
公开(公告)号：US07638771B2
公开(公告)日：2009-12-29
申请号：US11749434
申请日：2007-05-16
申请人： John E. Breeding , Michael E. Casey , William F Jones
发明人： John E. Breeding , Michael E. Casey , William F Jones
IPC分类号： G01T1/166
CPC分类号： G06T11/005
摘要： A system for generating time-of-flight (TOF) positron emission tomography (PET) projection data includes a direct memory access rebinner constructed as a digital FPGA pipeline for rebinning TOF coincidence data in accordance with a number of projection space mapping algorithms, such as single-slice rebinning (SSRB) and reduced multiple-slice rebinning (MSRB), together with less precise transaxial and/or axial sampling.
摘要翻译：用于产生飞行时间（TOF）正电子发射断层摄影（PET）投影数据的系统包括构造为数字FPGA流水线的直接存储器访问重组器，用于根据多个投影空间映射算法重新组合TOF重合数据，例如单片重组（SSRB）和减少的多片重组（MSRB），以及较不精确的横轴和/或轴向采样。

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