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51. 发明申请

US20120110993A1 METHOD AND APPARATUS TO STORE ENERGY 审中-公开
标题翻译：储存能源的方法和装置
公开(公告)号：US20120110993A1
公开(公告)日：2012-05-10
申请号：US13318543
申请日：2010-06-30
申请人： Kenneth Whittaker , David Ellis
发明人： Kenneth Whittaker , David Ellis
IPC分类号： F01K15/02 , B60H1/00 , F22B33/00 , F02G1/043
CPC分类号： F01K3/02 , F01K3/10 , F28D20/021 , F28D2020/0026 , Y02E60/145
摘要： A method to store energy, the method comprising: (b) providing a phase change material, having a melting point of at least 500° C., in a container; (c) heating the phase change material to cause at least a portion thereof to melt and so store heat therein; (d) storing the phase change material for a period of time being at least one minute; (e) using at least a portion of heat from the phase change material as a power source; (e) moving the container and the phase change material from a first location to a second location, the first and second locations being spaced apart by at least 10 metres. Embodiments of the invention may be used for a variety of purposes, such as for vehicle propulsion, oil well stimulation and recovery of crude oil from sunken tankers. A vehicle may be moved to a location proximate to where the power source is required which is more convenient and indeed allows steam to be supplied in areas which where hitherto not possible. For certain embodiments the power source produced is used to propel a vehicle comprising the power source. Certain embodiments use a Stirling engine whilst others generate a steam source. In preferred embodiments steam is recovered after use as the power source and preferably reheated as per step (e).
摘要翻译：一种存储能量的方法，所述方法包括：（b）在容器中提供熔点至少为500℃的相变材料; （c）加热相变材料，使其至少一部分熔化，从而在其中储存热量; （d）将相变材料储存至少1分钟; （e）使用来自所述相变材料的至少一部分热量作为电源; （e）将容器和相变材料从第一位置移动到第二位置，第一和第二位置间隔开至少10米。本发明的实施例可以用于各种目的，例如用于车辆推进，油井刺激和从凹下的油轮中回收原油。车辆可以移动到靠近需要电源的位置，这更方便，并且确实允许在迄今为止不可能的区域中供应蒸汽。对于某些实施例，所产生的电源用于推动包括电源的车辆。某些实施例使用斯特林发动机，而另一些则产生蒸汽源。在优选实施例中，蒸汽在使用后作为电源回收，并且优选地按照步骤（e）再加热。

52. 发明申请

US20120065801A1 METHOD AND SYSTEM FOR CONTROLLING A BUILDING LOAD IN TANDEM WITH A REPLENISHABLE ENERGY SOURCE IN ORDER TO INCREASE THE APPARENT SIZE OF THE REPLENISHABLE ENERGY SOURCE 审中-公开
标题翻译：用可替换能源来控制建筑物负荷的方法和系统，以增加可再生能源的平均尺寸
公开(公告)号：US20120065801A1
公开(公告)日：2012-03-15
申请号：US13229739
申请日：2011-09-11
申请人： John Rossi , David Ellis
发明人： John Rossi , David Ellis
IPC分类号： G06F1/26
CPC分类号： G06F1/263 , H02J3/14 , H02J3/32 , H02J13/0006 , H02J2003/143 , Y02B70/3225 , Y02B70/3266 , Y02B90/222 , Y04S20/12 , Y04S20/222 , Y04S20/242
摘要： A method and system for controlling a building load in tandem with a replenishable energy source includes generating a control signal comprising at least one of a source command and a sink command. The control signal is transmitted over a communications network to a replenishable energy storage controller. Next, a capacity of the replenishable energy source is determined in response to the control signal. Then a capacity of the building load is determined in relation to the capacity of the replenishable energy source. After this determination, the building load is used as one of a source for supplying energy and a sink for receiving energy in response to the control signal. The replenishable energy source may also be used as a source for supplying energy or a sink for receiving energy in response to the command signal.
摘要翻译：一种用于与可补充能量源一起控制建筑物负载的方法和系统包括产生包括源命令和宿指令中的至少一个的控制信号。控制信号通过通信网络传输到可补充的储能控制器。接下来，响应于控制信号确定可补充能量源的容量。然后建立负载的容量相对于可补充能源的容量来确定。在该确定之后，建筑物负载被用作响应于控制信号而提供能量的源和用于接收能量的接收器之一。补充能量源也可以用作供应能量的源或用于响应于命令信号接收能量的宿。

53. 发明申请

US20070269526A1 Carotenoid Composition and Method for Preparation Thereof 有权
标题翻译：类胡萝卜素组合物及其制备方法
公开(公告)号：US20070269526A1
公开(公告)日：2007-11-22
申请号：US11576276
申请日：2005-09-29
申请人： Michael Bos , David Ellis
发明人： Michael Bos , David Ellis
IPC分类号： A61K9/14 , A61K31/015 , A61P17/00 , A61K31/047
CPC分类号： A23K20/179 , A23D7/0053 , A23D9/007 , A23D9/02 , A23K20/174 , A23L5/44 , A23V2002/00 , A61K8/31 , A61K9/0014 , A61K9/14 , A61K9/145 , A61K31/015 , A61K2800/413 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61Q19/007 , A61Q19/02 , B82Y5/00 , C07C403/24 , A23V2200/254 , A23V2250/5036
摘要： This invention relates to a carotenoid composition comprising the carotenoid as particles of size smaller than 100 nanometers in an oil medium and a method of preparing the composition by milling the carotenoid in an oil medium and therapeutic compositions containing the carotenoid.
摘要翻译：本发明涉及一种类胡萝卜素组合物，其包含在油介质中含有尺寸小于100纳米的类胡萝卜素的类胡萝卜素，以及通过研磨油介质中的类胡萝卜素和含有类胡萝卜素的治疗组合物制备组合物的方法。

54. 发明申请

US20060112000A1 Method of trading a financial instrument using stop-order quantity 审中-公开
标题翻译：使用止损数量交易金融工具的方法
公开(公告)号：US20060112000A1
公开(公告)日：2006-05-25
申请号：US10994918
申请日：2004-11-22
申请人： David Ellis , David Wilkins
发明人： David Ellis , David Wilkins
IPC分类号： G06Q40/00
CPC分类号： G06Q40/04
摘要： A stop quantity order (SQO) on a market-traded instrument for a computerized trading system. An order to buy [sell] instrument X is an SQO if, in addition to a limit price, and a stop price, it also specifies a stop quantity SQ. It is triggered by either of the following two conditions: The market's best offer [bid] price for the instrument is greater [less] than the stop price, or the market's best offer price equals the stop price and the quantity offered [bid] at the best offer [bid] price is less than or equal to the stop quantity. Once triggered, it is submitted to the market as a limit order at the limit price. General stop quantity Orders (GSQO) are similar to SQO's, but use two markets, one as a trigger instrument, and one as a trade instrument. An order to buy [sell] instrument X is a GSQO if it specifies a limit price, stop price, stop quantity SQ, a stop instrument Y, and a stop direction SD (bid or offer). It is triggered by one of the following two conditions: The stop direction is “offer”, [“bid]”, and the market's best offer [bid] price for instrument Y is greater [less] than the stop price, or the quantity offered [bid] at the best offer [bid] price is less than or equal to the stop quantity, and, once triggered, it is submitted to the market as a limit order at the limit price for instrument X.
摘要翻译：电子交易系统市场交易工具上的停止订单（SQO）。购买[出售]仪器X的订单是SQO，如果除限价和止损价之外，还指定止损量SQ。它是由以下两个条件之一触发的：市场上最优惠的报价价格比止损价格更大，或市场最优惠的价格等于停止价格和提供的数量[投标] 最佳报价[bid]价格小于或等于停止数量。一旦触发，它作为限价订单以限价方式提交给市场。一般停止数量订单（GSQO）与SQO类似，但使用两个市场，一个作为触发工具，一个作为交易工具。如果指定限价，停止价格，停止数量SQ，停止票据Y和停止方向SD（出价或报价），购买[出售]票据X的订单是GSQO。由以下两个条件之一触发：停止方向为“报价”，[“投标”]，Y方的市场最佳报价[bid]价格大于止价，或数量以最优惠价格[bid]价格提供的[bid]价格小于或等于停止数量，一旦触发，则作为限价订单以限价单提交给仪器X.

55. 发明申请

US20050192218A1 Method for reducing pain 有权
标题翻译：减轻疼痛的方法
公开(公告)号：US20050192218A1
公开(公告)日：2005-09-01
申请号：US10956252
申请日：2004-10-01
申请人： David Ellis , George Miljanich , David Shields
发明人： David Ellis , George Miljanich , David Shields
IPC分类号： A61K31/195 , A61K31/4168 , A61K31/445 , A61K31/4468 , A61K31/4535 , A61K31/485 , A61K38/17 , A61K45/06 , A61P25/04
CPC分类号： A61K38/1767 , A61K9/0085 , A61K31/137 , A61K31/195 , A61K31/4168 , A61K31/445 , A61K31/4468 , A61K31/451 , A61K31/4535 , A61K31/485 , A61K38/17 , A61K45/06 , A61K47/12 , A61K47/183 , C07K14/43504 , A61K2300/00
摘要： The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
摘要翻译：本发明直接涉及在哺乳动物受试者中产生止痛的方法。该方法包括向受试者施用欧米加多肽，优选西科肽，与选自吗啡，布比卡因，可乐定，氢吗啡酮，巴氯芬，芬太尼，丁丙诺啡和舒芬太尼的止痛剂或其药学上可接受的盐组合，其中欧米加肽保留其效力并且与止痛化合物物理和化学相容。优选的给药途径是鞘内给药，特别是连续鞘内输注。本发明还涉及一种药物制剂，其包含ω-配肽，优选齐考诺铵，与选自吗啡，布比卡因，可乐定，氢吗啡酮，巴氯芬，芬太尼，丁丙诺啡和舒芬太尼的止痛剂组合。

56. 发明授权

US06211223B1 Indole derivatives useful in therapy 失效
标题翻译：吲哚衍生物用于治疗
公开(公告)号：US06211223B1
公开(公告)日：2001-04-03
申请号：US09551779
申请日：2000-04-18
申请人： Stephen Challenger , Kevin Neil Dack , Andrew Michael Derrick , Roger Peter Dickinson , David Ellis , Yousef Hajikarimian , Kim James , David James Rawson
发明人： Stephen Challenger , Kevin Neil Dack , Andrew Michael Derrick , Roger Peter Dickinson , David Ellis , Yousef Hajikarimian , Kim James , David James Rawson
IPC分类号： A61K31404
CPC分类号： C07D405/06
摘要： The invention provides S-(+)-3-{1-(1,3-benzodioxol-5-yl)-2-[(2-methoxy-4-methylphenyl)sulfonylamino]-2-oxoethyl}-1-methyl-1H-indole-6-carboxylic acid, which is substantially free from its (R)-(−)-enantiomer, and pharmaceutically acceptable derivatives thereof. The compounds are useful in the treatment of inter alia acute renal failure, restenosis and pulmonary hypertension.
摘要翻译：本发明提供了S - （+） - 3- {1-（1,3-苯并间二氧杂环戊烯-5-基）-2 - [（2-甲氧基-4-甲基苯基）磺酰基氨基] -2-氧代乙基} -1-甲基基本上不含其（R） - （ - ） - 对映异构体的-1H-吲哚-6-羧酸及其药学上可接受的衍生物。该化合物可用于治疗尤其是急性肾衰竭，再狭窄和肺动脉高压

57. 发明授权

US5861393A Antithrombotic amidinophenylalanine and amidinopyridylalanine derivatives 失效
标题翻译：抗疟原酸脒基苯丙氨酸和脒基吡啶基丙氨酸衍生物
公开(公告)号：US5861393A
公开(公告)日：1999-01-19
申请号：US902917
申请日：1997-07-30
申请人： John Christopher Danilewicz , David Ellis , Ryszard Jurek Kobylecki
发明人： John Christopher Danilewicz , David Ellis , Ryszard Jurek Kobylecki
IPC分类号： A61K31/47 , A61K31/55 , A61K38/00 , A61P7/02 , A61P9/08 , A61P9/10 , C07D401/12 , C07D401/14 , C07K5/065
CPC分类号： C07D401/12
摘要： This invention relates to compounds of formula (I), ##STR1## pharmaceutically acceptable salt thereof, and pharmaceutically acceptable solvates of either entity, wherein X is CH or N; Y is optionally monousaturated C.sub.3 -C.sub.5 alkylene optionally substituted with C.sub.1 -C.sub.4 allyl or methylene; R.sup.1 is H; C.sub.1 -C.sub.4 alkyl optionally substituted with C.sub.1 -C.sub.4 alkoxy, OH, NR.sup.5 R.sup.6, CONR.sup.5 R.sup.6, C.sub.3 -C.sub.6 cycloalkyl or aryl; or C.sub.3 -C.sub.6 alkenyl; R.sup.2 is H; C.sub.1 -C.sub.4 alkyl optionally substituted with C.sub.1 -C.sub.4 alkoxy, OH, NR.sup.5 R.sup.6, CONR.sup.5 R.sup.6, C.sub.3 -C.sub.6 cycloalkyl or aryl; or CONR.sup.5 R.sup.6 ; R.sup.3 and R.sup.4 are each independently selected from H; C.sub.1 -C.sub.4 alkyl optionally substituted with NR.sup.5 R.sup.6 ; C.sub.1 -C.sub.4 alkoxy; halo; CONR.sup.5 R.sup.6 and aryl; and R.sup.5 and R.sup.6 are each independently selected from H and C.sub.1 -C.sub.4 alkyl; are potent and selective thrombin inhibitors useful in the treatment of, inter alia, deep vein thrombosis; reocclusion following thrombolytic therapy; chronic arterial obstruction; peripheral vascular disease; acute myocardial infarction; unstable angina; atrial fibrillation; thrombotic stroke; transient ischaemic attacks; restenosis and occlusion following angioplasty; or neurodegenerative disorders.
摘要翻译：本发明涉及式（I）化合物，其药学上可接受的盐，以及任一实体的药学上可接受的溶剂化物，其中X为CH或N; Y任选被C1-C4烯丙基或亚甲基取代的单饱和C 3 -C 5亚烷基; R1是H; 任选被C 1 -C 4烷氧基，OH，NR 5 R 6，CONR 5 R 6，C 3 -C 6环烷基或芳基取代的C 1 -C 4烷基; 或C 3 -C 6烯基; R2为H; 任选被C 1 -C 4烷氧基，OH，NR 5 R 6，CONR 5 R 6，C 3 -C 6环烷基或芳基取代的C 1 -C 4烷基; 或CONR5R6; R3和R4各自独立地选自H; 任选被NR 5 R 6取代的C 1 -C 4烷基; C1-C4烷氧基; 光环; CONR5R6和芳基; 并且R 5和R 6各自独立地选自H和C 1 -C 4烷基; 是有效和选择性的凝血酶抑制剂，可用于治疗特别是深静脉血栓形成; 溶栓治疗后再闭塞; 慢性动脉阻塞; 周边血管疾病; 急性心肌梗塞; 不稳定型心绞痛; 房颤; 血栓性脑卒中短暂性脑缺血发作; 血管成形术后再狭窄和闭塞; 或神经变性疾病。

58. 发明授权

US5440592A Method and apparatus for measuring frequency and high/low time of a digital signal 失效
标题翻译：用于测量数字信号的频率和高/低时间的方法和装置
公开(公告)号：US5440592A
公开(公告)日：1995-08-08
申请号：US40623
申请日：1993-03-31
申请人： David Ellis , Gary Brady
发明人： David Ellis , Gary Brady
IPC分类号： G01R23/02 , G01R31/30 , H04L7/00
CPC分类号： G01R23/02 , G01R31/30
摘要： A delay chain having a known number of delay elements providing various delayed outputs of its input, a first and a second register set, and preferably, an array of multiplexors, are provided to measure the frequency of a digital signal, and the high and low time of its period. The digital signal to be measured is provided to the delay chain as input. A first and a second sample of the various delayed outputs are taken at the beginning and the end of a known time period, and stored in the first and second registers, one delayed output per register bit. The sample results stored in the register sets are read out through the multiplexors, and used to determine the frequency of the digital signal being measured, and the high and low time of its period.
摘要翻译：提供具有已知数量的延迟元件的延迟链，其提供其输入，第一和第二寄存器组，以及优选地，多路复用器阵列的各种延迟输出，以测量数字信号的频率，以及高低时间的时间。要测量的数字信号作为输入提供给延迟链。各种延迟输出的第一和第二采样在已知时间周期的开始和结束时获取，并存储在第一和第二寄存器中，每个寄存器位一个延迟的输出。存储在寄存器组中的采样结果通过多路复用器读出，用于确定正在测量的数字信号的频率以及其周期的高低时间。

59. 发明授权

US4910305A Pyridyl and pyridazinyl substituted thyronine compounds 失效
标题翻译：吡啶基和哒嗪基取代的甲腺苷化合物
公开(公告)号：US4910305A
公开(公告)日：1990-03-20
申请号：US168780
申请日：1988-03-16
申请人： David Ellis , John C. Emmett , Anthony H. Underwood , Paul D. Leeson
发明人： David Ellis , John C. Emmett , Anthony H. Underwood , Paul D. Leeson
IPC分类号： A61K31/135 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/215 , A61K31/44 , A61K31/4418 , A61K31/50 , A61P3/06 , A61P5/12 , C07C45/67 , C07C45/71 , C07C51/00 , C07C65/105 , C07C65/24 , C07C67/00 , C07C69/94 , C07C201/00 , C07C205/38 , C07C205/56 , C07C205/57 , C07C213/00 , C07C215/74 , C07C231/00 , C07C231/12 , C07C233/13 , C07C233/18 , C07C233/36 , C07C233/47 , C07C235/46 , C07C237/30 , C07C313/00 , C07C323/37 , C07C323/62 , C07D213/64 , C07D213/65 , C07D237/12 , C07D237/14 , C07D413/12
CPC分类号： C07D213/64 , C07C45/673 , C07C45/71 , C07D213/65 , C07D237/12 , C07D237/14 , C07D413/12
摘要： This invention relates to chemical compounds which have selective thyromimetic activity. A compound of this invention is 3,5-dibromo-3'-[6-oxo-3(1H)-pyridazinylmethyl]-thyronine.

60. 发明授权

US4826876A Chemical compounds having selective thyromimetic activity 失效
标题翻译：具有选择性甲状腺发生活性的化合物
公开(公告)号：US4826876A
公开(公告)日：1989-05-02
申请号：US136240
申请日：1987-12-21
申请人： David Ellis , John C. Emmett , Anthony H. Underwood , Paul D. Leeson
发明人： David Ellis , John C. Emmett , Anthony H. Underwood , Paul D. Leeson
IPC分类号： A61K31/135 , A61K31/165 , A61K31/19 , A61K31/195 , A61K31/215 , A61K31/44 , A61K31/4418 , A61K31/50 , A61P3/06 , A61P5/12 , C07C45/67 , C07C45/71 , C07C51/00 , C07C65/105 , C07C65/24 , C07C67/00 , C07C69/94 , C07C201/00 , C07C205/38 , C07C205/56 , C07C205/57 , C07C213/00 , C07C215/74 , C07C231/00 , C07C231/12 , C07C233/13 , C07C233/18 , C07C233/36 , C07C233/47 , C07C235/46 , C07C237/30 , C07C313/00 , C07C323/37 , C07C323/62 , C07D213/64 , C07D213/65 , C07D237/12 , C07D237/14 , C07D413/12 , C07C101/72 , A61K31/24
CPC分类号： C07D213/64 , C07C45/673 , C07C45/71 , C07D213/65 , C07D237/12 , C07D237/14 , C07D413/12
摘要： This invention relates to chemical compounds which have selective thyromimetic activity. A compound of this invention is 3,5-dibromo-3'-[6-oxo-3(1H)-pyridazinyl-methyl]-thyronine.

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