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    • 52. 发明申请
    • Fuel supply apparatus and fuel pressure regulator
    • 燃油供应装置和燃油压力调节器
    • US20050056257A1
    • 2005-03-17
    • US10493579
    • 2002-05-29
    • Hiroshi YoshiokaHisashi Kuwada
    • Hiroshi YoshiokaHisashi Kuwada
    • F02M37/00F02M37/10F02M37/22F02M69/26F02M69/54F02M1/00
    • F02M37/10F02M37/106F02M37/221F02M69/26F02M69/54F02M2037/225F02M2037/226Y10T137/7766Y10T137/7838Y10T137/87555
    • A fuel supply apparatus having a fuel pressure regulator (60) for regulating the pressure of fuel discharged from a fuel pump (4) to a predetermined pressure, the fuel pressure regulator (60) including: a first chamber (62), formed in a case (61), into which fuel discharged from the fuel pump (4) flows, and a second chamber (63), into which the fuel flows via the first chamber (62); a fuel limiting means (64) disposed between the first chamber (62) and the second chamber (63), for limiting fuel flowing from the first chamber (62) into the second chamber (63); a pilot valve unit (65) having a passageway for opening to discharge fuel tank (2), when the fuel pressure in the second chamber (63) is more than a first set pressure (Pp); and a main valve unit (66) having a passageway for opening to discharge fuel into the fuel tank (2) when the fuel pressure in the first chamber (62) is equal to a second set pressure (Pm) between the first set pressure (Pp) and the predetermined pressure (Pi), whereby, in cases where returning flow volume drops, the pressure of the fuel delivered under pressure to the injector does not drop.
    • 一种燃料供给装置,具有用于调节从燃料泵(4)排出的燃料的压力达到预定压力的燃料压力调节器(60),所述燃料压力调节器(60)包括:第一室(62),形成在 从燃料泵(4)排出的燃料流入的壳体(61)和燃料通过第一室(62)流过的第二室(63); 设置在第一室(62)和第二室(63)之间的燃料限制装置(64),用于限制从第一室(62)流入第二室(63)的燃料; 当所述第二室(63)中的燃料压力大于第一设定压力(Pp)时,具有用于打开以排放燃料箱(2)的通道的先导阀单元(65); 以及主阀单元(66),当第一室(62)中的燃料压力等于第一设定压力(Pm)之间时,具有用于打开燃料以将燃料排放到燃料箱(2)中的通道的主阀单元(66) Pp)和预定压力(Pi),由此,在返回流量下降的情况下,在压力下输送到喷射器的燃料的压力不会下降。
    • 53. 发明授权
    • Fuel feed device
    • 燃油进给装置
    • US06655364B1
    • 2003-12-02
    • US10110536
    • 2002-04-15
    • Hiroshi Yoshioka
    • Hiroshi Yoshioka
    • F02M3704
    • F02M37/22B01D29/70B01D35/0273B01D35/26F02M37/10F02M37/103F02M2037/225F02M2037/226F02M2037/228
    • A fuel supply system in which a fuel filter has a large filtration area is obtained without increasing an outer diameter of the fuel supply system and an outer diameter of a tank hole through which a pump module is inserted in a fuel tank. The fuel supply system comprises a fuel pump 5, a fuel pressure regulator 9 for regulating pressure of fuel, and a fuel filter 6 having a hollow cylindrical filter case 7for filtering the fuel, and in which the filter case 7 has a holding hole 7a for holding the fuel pump, a center line CL1 of the holding hole is eccentric with respect to a center line CL2 of the filter case 7 by a predetermined distance M, and a first enlarged space portion S1 in which fuel system parts such as fuel pressure regulator 9 are accommodated is formed at a part surrounded by an outer circumferential portion of the fuel pump 5 and an outer circumferential portion of the filter case 7.
    • 在不增加燃料供给系统的外径和泵模块插入燃料箱中的罐孔的外径的情况下,获得燃料过滤器具有大的过滤面积的燃料供给系统。 燃料供给系统包括燃料泵5,用于调节燃料压力的燃料压力调节器9和具有用于过滤燃料的中空圆柱形过滤器壳体7的燃料过滤器6,其中过滤器壳体7具有用于 保持燃料泵,保持孔的中心线CL1相对于过滤器壳体7的中心线CL2偏心预定距离M,以及第一扩大空间部S1,其中燃料系统部件例如燃料压力调节器 9被容纳在由燃料泵5的外周部分包围的部分和过滤器壳体7的外周部分上。
    • 56. 发明授权
    • Fuel feeder for vehicles
    • 车辆用燃料给料机
    • US06065452A
    • 2000-05-23
    • US341875
    • 1999-07-19
    • Hiroshi Yoshioka
    • Hiroshi Yoshioka
    • B60K15/077F02M37/10F02M37/14F02M37/22F02M37/04
    • B60K15/077F02M37/106F02M37/14F02M37/22B60K2015/03105B60K2015/03236B60K2015/03467B60K2015/0777F02M2037/225F02M2037/226
    • A vehicular fuel supply apparatus in which a sub-tank 21 that is inserted into and attached to the bottom wall opening 1b of the fuel tank 1 has integrally formed therein by molding a fuel chamber 24, support cavities 7c, 22c, 23c and a fuel flow paths 27 and 29, and a fuel pump 7, a fuel filter 22 and a pressure regulator 23 are accommodated and supported within the respective support cavities. The fuel chamber 24 is substantially closed against a rush flow of the fuel except for the air vent hole 24b and the fuel inlet port 24a through which the fuel flows at a predetermined flow rate per time, and has formed in the wall surface of the fuel pump support cavity 7c a groove 38 for accommodating and supporting a power supply line 11. Parts for assembling the components or elements of the apparatus are not necessary and the weight and the parts number is decreased, resulting in an easy assembly and a small cost. Also, the fuel does not flow out from the sub-tank even at the time of the abrupt acceleration or deceleration of the vehicle.
    • PCT No.PCT / JP97 / 04214 Sec。 371日期1999年7月19日第 102(e)日期1999年7月19日PCT 1997年11月19日PCT公布。 出版物WO99 /​​ 25975 日期1999年5月27日一种车辆燃料供给装置,其中插入并附接到燃料箱1的底壁开口1b的副罐21通过模制燃料室24,支撑腔7c,22c, 23c和燃料流路27和29,并且燃料泵7,燃料过滤器22和压力调节器23容纳并支撑在相应的支撑腔内。 燃料室24基本上与除了通气孔24b和燃料入口24a之间的燃料的急流相对应,燃料入口端口24a以每个时间预定的流量流过燃料,并且形成在燃料的壁表面中 泵支撑腔7c具有用于容纳和支撑电源线11的凹槽38.用于组装装置的部件或部件的部件不是必需的,并且重量和部件数量减少,导致组装容易和成本低。 此外,即使在车辆的急剧加速或减速时,燃料也不会从副罐流出。
    • 57. 发明授权
    • Inhibition adsorption of proteins on the liposome surface
    • 抑制蛋白质在脂质体表面的吸附
    • US5846458A
    • 1998-12-08
    • US677122
    • 1996-07-09
    • Hiroshi YoshiokaHiroshi Goto
    • Hiroshi YoshiokaHiroshi Goto
    • A61K9/127A61K38/16A61K47/34A61P7/08B01J13/02B01J13/22
    • A61K9/1271A61K9/1272Y10S514/832Y10T428/2984
    • Agents for inhibiting adsorption of proteins on the liposome surface and liposomes which are agglutination-free by binding said inhibiting agent on the surface are disclosed. The above-mentioned inhibiting agents comprise a hydrophobic moiety and a hydrophilic macromolecular chain moiety. Adsorption of plasma proteins on the liposomes is inhibited due to the hydrophilic moiety exposed on the liposome surface with a result that agglutination of the liposomes in plasma is prevented. Therefore, there is no danger of embolism in blood vessels inhibiting blood flow when the liposomes are introduced into the living body. Accordingly, the liposomes are especially highly useful as artificial erythrocytes for which a large dose of liposomes is needed for administration. Moreover, when liposomes are introduced into the living body, antibody protein (immunoglobulin) to the liposome which is an antigen will be adsorbed on the liposome to produce foreign body recognition in the phagocytes (macrophage) with a result that the liposome will be included in the macrophage and disappear within a short period of time. Thus, inhibition of the protein adsorption on liposome can delay disappearance of the liposome in plasma. In addition, a method for preparing the above-described liposomes is disclosed.
    • 公开了通过在表面上结合所述抑制剂来抑制脂质体表面上的蛋白质吸附和不凝集的脂质体的试剂。 上述抑制剂包含疏水部分和亲水性大分子链部分。 血浆蛋白在脂质体上的吸附由于在脂质体表面上暴露的亲水部分而受到抑制,从而阻止了血浆中脂质体的凝集。 因此,当将脂质体引入生物体时,血管阻塞血栓的危险不存在。 因此,脂质体特别高度用作需要大剂量脂质体用于给药的人造红细胞。 此外,当将脂质体引入生物体中时,作为抗原的脂质体的抗体蛋白质(免疫球蛋白)将被吸附在脂质体上,以在吞噬细胞(巨噬细胞)中产生异物识别,结果将脂质体包含在 巨噬细胞在短时间内消失。 因此,抑制脂质体上的蛋白质吸附可以延迟脂质体在血浆中的消失。 此外,公开了制备上述脂质体的方法。