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51. 发明申请

US20120289423A1 ONLINE REAL-TIME WATER QUALITY MONITORING AND CONTROL SYSTEM INCORPORATING SYSTEMS FOR AUTOMATED MICROBIOLOGICAL TESTING AND ONE-STEP DNA DETECTION 审中-公开
标题翻译：在线实时水质监测和控制系统自动化微生物测试和一步DNA检测的合成系统
公开(公告)号：US20120289423A1
公开(公告)日：2012-11-15
申请号：US13465777
申请日：2012-05-07
申请人： Michael Kane , Bruce Applegate , Sergei Savikhin , James Walsh , Paul Duffy , Gerry Woods
发明人： Michael Kane , Bruce Applegate , Sergei Savikhin , James Walsh , Paul Duffy , Gerry Woods
IPC分类号： C40B40/06 , C40B30/04 , G01N21/64
CPC分类号： G01N21/6428 , B01L3/5027 , B01L7/52 , B01L2200/143 , B01L2300/0636 , B01L2300/1822 , G01N2021/6441
摘要： A system for detecting deoxyribonucleic acid (DNA) biomarkers. The system is configured to monitor and control standard parameters (temperature, pH, free chlorine, redox potential, TDS, turbidity), via an array of sensors. The system is configured to perform automated microbiological testing using a DNA hybridization based optical detection sensor, wherein the sensor is configured to provide automated sample collection, primer and buffer addition, thermocycling and fluorescence detection via laser excitation and a linear CCD.
摘要翻译：一种检测脱氧核糖核酸（DNA）生物标志物的系统。该系统配置为通过一组传感器监控和控制标准参数（温度，pH，游离氯，氧化还原电位，TDS，浊度）。该系统被配置为使用基于DNA杂交的光学检测传感器进行自动化微生物测试，其中所述传感器被配置为通过激光激发和线性CCD提供自动采样，引物和缓冲液添加，热循环和荧光检测。

52. 发明申请

US20110319954A1 METRICS AND TECHNIQUES FOR OPTIMIZATION OF CARDIAC THERAPIES 审中-公开
标题翻译：用于优化心脏病治疗的方法和技术
公开(公告)号：US20110319954A1
公开(公告)日：2011-12-29
申请号：US12825063
申请日：2010-06-28
申请人： Imran Niazi , Kyungmoo Ryu , Peter Chelius , Scott Patrick Simon , Michael Kane , Timothy A. Fayram
发明人： Imran Niazi , Kyungmoo Ryu , Peter Chelius , Scott Patrick Simon , Michael Kane , Timothy A. Fayram
IPC分类号： A61N1/00
CPC分类号： A61N1/3627 , A61B5/0215 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/11 , A61B5/686 , A61N1/3684 , A61N1/3686 , G06F19/3481 , G16H50/20
摘要： An exemplary method includes, based on metrics available as input to a chronic phase optimization algorithm for selecting an optimal electrode configuration for delivery of a cardiac pacing therapy, executing the chronic phase optimization algorithm during an acute phase to select an optimal electrode configuration for delivery of a cardiac pacing therapy; during the acute phase, acquiring position information with respect to time for electrodes implanted in a body; determining one or more acute phase metrics based on the acquired position information; and validating the chronic phase optimization algorithm based at least in part on the one or more acute phase metrics.
摘要翻译：示例性方法包括：基于可用作用于选择用于递送心脏起搏治疗的最佳电极配置的慢性相位优化算法的输入的度量，在急性期期间执行慢性相位优化算法，以选择用于递送心脏起搏治疗; 在急性期，获取相对于植入体内的电极的时间的位置信息; 基于所获取的位置信息确定一个或多个急性相位度量; 以及至少部分地基于所述一个或多个急性相位度量来验证所述慢性相位优化算法。

53. 发明申请

US20110077962A1 SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES 审中-公开
标题翻译：促进中心候选人选择和监测临床试验研究中的主体参与的系统和方法
公开(公告)号：US20110077962A1
公开(公告)日：2011-03-31
申请号：US12963765
申请日：2010-12-09
申请人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
发明人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
IPC分类号： G06Q50/00 , G06Q10/00
CPC分类号： G06Q10/10 , G06Q10/06393 , G06Q30/0203 , G06Q50/22 , G06Q50/24 , G06Q99/00 , G16H10/20
摘要： A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results.
摘要翻译：在临床试验研究中促进受试者的集中和标准化远程评级的系统和方法包括向位于一个或多个中心评价点的评估者提供培训，使得评估者被训练以在确定候选人是否合格的受试者时应用基本相似的标准用于临床试验和/或实际评估，或信息收集阶段的临床踪迹。通过拥有独立于临床试验研究者的集中，一致训练的评估者，提高了评估者的可靠性，减少潜在的偏差，从而通过提供更多的合格科目和更准确的结果来提高临床试验结果的有效性。

54. 发明申请

US20100211581A1 OPEN ARCHITECTURE VEHICLE INFORMATION MODULE AND SYSTEM AND METHOD THEREOF 审中-公开
标题翻译：开放式建筑物车辆信息模块及其系统及方法
公开(公告)号：US20100211581A1
公开(公告)日：2010-08-19
申请号：US12372350
申请日：2009-02-17
申请人： Jennifer KOTSKI , Conrad Coffman , Michael Kane , John J. Cole , Patrick Jesse , Matthew Leas
发明人： Jennifer KOTSKI , Conrad Coffman , Michael Kane , John J. Cole , Patrick Jesse , Matthew Leas
IPC分类号： G06F17/30 , B60Q1/00 , G08B21/00 , G06F15/16
CPC分类号： G07C5/008 , G07C5/085
摘要： A module, system, and method for presenting vehicle data to a client. A vehicle information module (VIM) is configured to interpret, store, and communicate to interested clients the status of a vehicle. Interested clients or end-users may include a GUI, a database, an Interrogative Diagnostics & Prognostics System and other future stakeholders, such as a fleet management system, a logistics system, a maintenance system, and a mobile personal digital assistant.
摘要翻译：用于向客户端呈现车辆数据的模块，系统和方法。车辆信息模块（VIM）被配置为对感兴趣的客户端解释，存储和通信车辆的状态。感兴趣的客户或最终用户可以包括GUI，数据库，询问诊断和预测系统以及其他未来的利益相关者，例如车队管理系统，物流系统，维护系统和移动个人数字助理。

55. 发明申请

US20100100397A1 SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES 审中-公开
标题翻译：促进中心候选人选择和监测临床试验研究中的主体参与的系统和方法
公开(公告)号：US20100100397A1
公开(公告)日：2010-04-22
申请号：US12643594
申请日：2009-12-21
申请人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
发明人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
IPC分类号： G06Q50/00
CPC分类号： G06Q10/10 , G06Q10/06393 , G06Q30/0203 , G06Q50/22 , G06Q50/24 , G06Q99/00 , G16H10/20
摘要： A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results.
摘要翻译：在临床试验研究中促进受试者的集中和标准化远程评级的系统和方法包括向位于一个或多个中心评价点的评估者提供培训，使得评估者被训练以在确定候选人是否合格的受试者时应用基本相似的标准用于临床试验和/或实际评估，或信息收集阶段的临床踪迹。通过拥有独立于临床试验研究者的集中，一致训练的评估者，提高了评估者的可靠性，减少潜在的偏差，从而通过提供更多的合格科目和更准确的结果来提高临床试验结果的有效性。

56. 发明授权

US07676459B2 Method and system for creating and maintaining an index for tracking files relating to people 有权
标题翻译：用于创建和维护跟踪与人相关的文件的索引的方法和系统
公开(公告)号：US07676459B2
公开(公告)日：2010-03-09
申请号：US11155386
申请日：2005-06-17
申请人： Trevor A. Carone , Batista Macario Gazoli , Matthew Michael Kane , Edgar A. Penaflor
发明人： Trevor A. Carone , Batista Macario Gazoli , Matthew Michael Kane , Edgar A. Penaflor
IPC分类号： G06F17/30 , G06F7/00
CPC分类号： G06Q40/02 , Y10S707/944 , Y10S707/99931 , Y10S707/99933 , Y10S707/99934 , Y10S707/99954
摘要： A computer system creates and maintains an index for tracking information relating to individuals. Such information can include, but is not limited to, social security numbers, names, address information, credit bureau identification numbers, and credit history information on individuals. The invention employs logical rules to this information in order to create and maintain a set of files for each individual. The logical rules can include social security rules, geography rules, and address ranking rules. The invention is designed to evaluate slight variations in information very carefully in order to insure that appropriate files are assigned the same index identification number or that appropriate records are assigned separate and different index identification numbers as a situation warrants. The present invention is designed to maintain numerous files for each individual being tracked instead of merging and purging files as is done in the conventional art.
摘要翻译：计算机系统创建和维护用于跟踪与个人有关的信息的索引。这些信息可以包括但不限于个人的社会保险号码，姓名，地址信息，信用局识别号码和信用记录信息。本发明对该信息采用逻辑规则，以便为每个个体创建和维护一组文件。逻辑规则可以包括社会保障规则，地理规则和地址排序规则。本发明旨在非常仔细地评估信息的轻微变化，以确保适当的文件被分配相同的索引标识号，或者适当的记录被分配和不同的索引识别号码作为情况。本发明被设计成为跟踪的每个个体维护许多文件，而不是像传统技术中那样进行合并和清除文件。

57. 发明申请

US20090132288A1 SYSTEM AND METHOD FOR FACILITATING CENTRALIZED CANDIDATE SELECTION AND MONITORING SUBJECT PARTICIPATION IN CLINICAL TRIAL STUDIES 审中-公开
标题翻译：促进中心候选人选择和监测临床试验研究中的主体参与的系统和方法
公开(公告)号：US20090132288A1
公开(公告)日：2009-05-21
申请号：US12349730
申请日：2009-01-07
申请人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
发明人： John Michael Kane , Paul Michael Gilbert , Livingston Johnson
IPC分类号： G06Q50/00
CPC分类号： G06Q10/10 , G06Q10/06393 , G06Q30/0203 , G06Q50/22 , G06Q50/24 , G06Q99/00 , G16H10/20
摘要： A system and method of facilitating centralized and standardized remote ratings of subjects in clinical trial studies includes providing training to raters located at one or more central rating sites such that the raters are trained to apply substantially similar criteria in determining whether a candidate is a qualified subject for the clinical trial and/or in the actual assessment, or information collection, phase of the clinical trail. By having centralized, consistently trained raters that are independent of clinical trial investigators, inter-rater reliability is enhanced and potential bias is reduced, thus increasing the effectiveness of the clinical trial results by providing more qualified subjects and more accurate results.
摘要翻译：在临床试验研究中促进受试者的集中和标准化远程评级的系统和方法包括向位于一个或多个中心评价点的评估者提供培训，使得评估者被训练以在确定候选人是否合格的受试者时应用基本相似的标准用于临床试验和/或实际评估，或信息收集阶段的临床踪迹。通过拥有独立于临床试验研究者的集中，一致训练的评估者，提高了评估者的可靠性，减少潜在的偏差，从而通过提供更多的合格科目和更准确的结果来提高临床试验结果的有效性。

58. 发明申请

US20080171682A1 Compositions for Cleaning Ion Implanted Photoresist in Front End of Line Applications 失效
标题翻译：用于清洁离子注入光刻胶的组合在前端应用
公开(公告)号：US20080171682A1
公开(公告)日：2008-07-17
申请号：US11817874
申请日：2006-03-13
申请人： Sean Michael Kane , Steven A. Lippy
发明人： Sean Michael Kane , Steven A. Lippy
IPC分类号： C11D11/00
CPC分类号： G03F7/423 , C11D3/3947 , C11D7/08 , C11D7/10 , C11D7/3263 , C11D7/34 , C11D7/5009 , C11D7/5013 , C11D11/0047 , G03F7/426 , H01L21/31133
摘要： A front end of the line (FEOL) stripping and cleaning composition for cleaning unashed ion-implanted photoresist from a wafer substrate comprises: a) at least one organic stripping solvent, b) fluoride ions from at least one of ammonium fluoride, ammonium bifluoride or hydrogen fluoride, c) at least one acidifying agent selected from inorganic or organic acids, and d) water, with an oxidizing agent optionally also being present in the composition.
摘要翻译：线路前端（FEOL）剥离和清洁组合物用于从晶片衬底清洁未曝光的离子植入光致抗蚀剂，包括：a）至少一种有机剥离溶剂，b）氟化铵，氟化铵或氟化铵中的至少一种的氟离子氟化氢，c）至少一种选自无机或有机酸的酸化剂，以及d）水，与组合物中任选地还含有氧化剂。

59. 发明申请

US20070088214A1 Implantable physiologic monitoring system 审中-公开
标题翻译：植入式生理监测系统
公开(公告)号：US20070088214A1
公开(公告)日：2007-04-19
申请号：US11250928
申请日：2005-10-14
申请人： Allan Shuros , Rodney Salo , Michael Kane
发明人： Allan Shuros , Rodney Salo , Michael Kane
IPC分类号： A61B8/00
CPC分类号： A61B8/065 , A61B5/076 , A61B5/1076 , A61B5/6876 , A61B5/6884 , A61B8/02 , A61B8/06 , A61B8/12 , A61B8/4483
摘要： An ultrasonic implantable device includes an ultrasonic sensor having a plurality of transducers. The sensor is configured for mounting to a vessel wall. A first of the transducers directs sound waves in a direction at least partially upstream or downstream in the vessel. A second of the transducers directs sound waves in a radial direction through an interior of the vessel against a sidewall of the vessel. The sensor monitors a change in frequency of the sound waves from the first transducer to determine a fluid velocity in the vessel. The sensor also monitors a reflection time of the sound waves from the second transducer that return from the sidewall to determine an internal diameter of the vessel. The determined fluid velocity and vessel diameter can be used to determine a volumetric flow rate of the fluid in the vessel.
摘要翻译：超声波可植入装置包括具有多个换能器的超声波传感器。传感器被配置为安装到血管壁。换能器中的第一个将声波沿至少部分在容器的上游或下游的方向引导。传感器中的第二个将声波沿径向引导通过容器的内部抵靠容器的侧壁。传感器监测来自第一换能器的声波的频率变化以确定容器中的流体速度。传感器还监测来自第二换能器的声波的反射时间，其从侧壁返回以确定容器的内径。确定的流体速度和容器直径可用于确定容器中流体的体积流量。

60. 发明授权

US07204037B2 Framer's tape hook 失效
标题翻译：成帧器的磁带钩
公开(公告)号：US07204037B2
公开(公告)日：2007-04-17
申请号：US11158904
申请日：2005-06-22
申请人： Michael Kane
发明人： Michael Kane
IPC分类号： G01B3/10
CPC分类号： G01B3/1056
摘要： The invention called a Framer's Tape Hook is a modification of a tape hook, which is attached to a retractable tape measure. The modification adds the capacity to offset the tape hook by ½ the thickness of any framing member. The purpose of this modification is to mark the edge locations of wall studs, floor and ceiling joist, rafters, and trusses. The Framer's Tape Hook can extend ¾ of an inch for dimension lumber. The Framer's Tape Hook can extend ⅝ of an inch for LGS, or light gauge steel studs. The Framer's Tape Hook can extend 1¼ inches for 2½ inch wide strapping. The Framer's Tape Hook can be set, to accommodate any stud, joist, or rafter size. The Framer's Tape Hook adds speed and accuracy when marking layout, whether it is a 16 inch on-center layout, 24 inch on-center layout, or any other desired layout.
摘要翻译：本发明称为成帧器的磁带挂钩是将磁带挂钩的修改，其附接到可伸缩卷尺。该修改增加了将胶带钩偏移1/2任何框架构件的厚度的能力。该修改的目的是标记墙壁螺柱，地板和天花板托梁，椽子和桁架的边缘位置。成帧器的胶带钩可以延伸3/4英寸的尺寸木材。成帧器的胶带钩可以延伸5/8英寸的LGS或轻型钢螺柱。成帧器的胶带钩可以延伸1¼英寸，用于2½英寸宽的捆扎带。成帧器的胶带钩可以设置，以适应任何螺柱，托梁或椽子尺寸。无论是16英寸的中心布局，24英寸的中心布局，还是其他所需的布局，Framer的Tape Hook在标记布局时增加了速度和精度。

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