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    • 58. 发明授权
    • Microprocessor system for the analysis of physiologic and financial datasets
    • 用于生理和金融数据集分析的微处理器系统
    • US07758503B2
    • 2010-07-20
    • US10150842
    • 2002-05-17
    • Lawrence A. LynnEric N. Lynn
    • Lawrence A. LynnEric N. Lynn
    • A61B5/00
    • A61B5/00A61B5/0205A61B5/021A61B5/0809A61B5/087A61B5/145A61B5/14551A61B5/412A61B5/4818A61B5/743G06F19/00G16H50/20G16H50/70
    • A system and method for organization and analysis of complex and dynamically interactive time series is disclosed. One example comprises a processor based system for relational analysis of physiologic signals for providing early recognition of catastrophic and pathologic events such as pathophysiologic divergence. The processor is programmed to identify pathophysiologic divergence of at least one of first and second physiologic parameters in relationship to the other and to output an indication of the divergence. An object-based method of iterative relational processing waveform fragments in the time domain is described wherein each more complex waveform object inherits the characteristics of the waveform objects from which it is derived. The first physiologic parameter can be the amplitude and frequency of the variation in chest wall impedance or nasal pressure and the second parameter can be a measure or indication of the arterial oxygen saturation.
    • 公开了一种用于组织和分析复杂和动态交互的时间序列的系统和方法。 一个例子包括基于处理器的系统,用于生理信号的关系分析,以提供灾难性和病理性事件(例如病理生理学发散)的早期识别。 处理器被编程为识别与另一个关系的第一和第二生理参数中的至少一个的病理发散,并输出发散的指示。 描述了时域中迭代关系处理波形片段的基于对象的方法,其中每个更复杂的波形对象继承了从其导出的波形对象的特性。 第一个生理参数可以是胸壁阻抗或鼻压变化的幅度和频率,第二个参数可以是动脉血氧饱和度的测量或指示。
    • 59. 发明申请
    • MICROPROCESSOR SYSTEM FOR THE ANALYSIS OF PHYSIOLOGIC AND FINANCIAL DATASETS
    • 生理和财务数据分析微波处理系统
    • US20100079292A1
    • 2010-04-01
    • US12629407
    • 2009-12-02
    • Lawrence A. LynnEric N. Lynn
    • Lawrence A. LynnEric N. Lynn
    • G08B23/00
    • A medical alarm system for processing physiologic and laboratory data in hospitals and other environments is disclosed. The alarm system provides early detection of complex pathophysiologic cascades. The alarm system detects aggregated timed patterns of inflammatory indicators, metabolic, pulse, blood pressure, oxygen saturation, and/or ventilation trends to detect expanding cascade patterns characteristic of, for example, progressive sepsis. The system may include a processor programmed to convert at least the physiologic and laboratory data of a patient into a predetermined format favorable for searching. The system may also include a processor programmed to search the formatted data to detect the progressively expanding global patterns of abnormal data characteristic of evolving sepsis and/or septic shock. The alarm system may be configured to provide an early warning for healthcare workers when a pattern indicative of progression of a complex pathophysiologic cascade is detected.
    • 公开了用于在医院和其他环境中处理生理和实验室数据的医疗报警系统。 报警系统提供复杂病理生物学级联的早期检测。 报警系统检测炎症指示剂,代谢,脉搏,血压,氧饱和度和/或通气趋势的聚合时间图,以检测例如渐进性败血症特征的扩张级联模式。 系统可以包括被编程为将至少将患者的生理学和实验室数据转换成有利于搜索的预定格式的处理器。 该系统还可以包括被编程为搜索格式化数据以检测逐渐扩大的异常数据异常数据的进化性败血症和/或败血性休克特征的全局模式的处理器的处理器。 警报系统可以被配置为当检测到指示复杂病理生物学级联进展的模式时,为医护人员提供预警。