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51. 发明授权

US11311377B2 Transcatheter atrio-ventricular valve prosthesis 有权
公开(公告)号：US11311377B2
公开(公告)日：2022-04-26
申请号：US16685018
申请日：2019-11-15
申请人： HIGHLIFE SAS
发明人： Josef Weber
IPC分类号： A61F2/24 , A61B17/064 , A61B17/122 , A61B17/128 , A61B17/00 , A61B17/04
摘要： A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular valve in a connection channel, having a circumferential connection channel wall structure, between atrial and ventricular chambers of a heart, including an inner device to be disposed in the interior of the connection channel, the inner device having a circumferential support structure which is radially expandable and having a valve attached to the circumferential support structure, and an outer device to be disposed on the exterior of the connection channel, wherein the outer device at least partly extends around the inner device at a radial distance to the inner device, wherein the inner and outer devices form a securing mechanism for securing the circumferential connection channel wall structure therebetween.

52. 发明授权

US11207184B2 Treatment catheter member with encircling function 有权
公开(公告)号：US11207184B2
公开(公告)日：2021-12-28
申请号：US16598623
申请日：2019-10-10
申请人： HIGHLIFE SAS
发明人： Georg Bortlein , Malek Nasr
IPC分类号： A61F2/24 , A61B17/00 , A61B17/04 , A61B17/221
摘要： A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.

53. 发明申请

US20210205077A1 TRANSCATHETER VALVE PROSTHESIS 有权
公开(公告)号：US20210205077A1
公开(公告)日：2021-07-08
申请号：US16736116
申请日：2020-01-07
申请人： HIGHLIFE SAS
发明人： Will WANG , Malek NASR , Georg BÖRTLEIN , Garrett OFFERMAN , Gilbert MADRID , Martin ROTHMAN , Glenn BALKE , Eric DIEP
IPC分类号： A61F2/24
摘要： A replacement heart valve system and a method of implanting a replacement heart valve in a patient. The replacement heart valve system includes a radially self-expandable tubular body and a valve including a plurality of leaflets coupled to the tubular body. The tubular body includes interconnected struts defining circumferential rows of cells, and has an outflow end and an inflow end that flares radially outward so as to have a larger outer diameter than that of the outflow end. A first row of proximal-most cells formed at the inflow end includes circumferentially adjacent cells that are disconnected from each other so as to be spaced from each other in the circumferential direction. A method of implanting the replacement heart valve includes delivering from a delivery catheter the tubular body, and expanding the tubular body such that the proximal-most cells are disposed against the native heart valve annulus.

54. 发明授权

US10828157B2 Transcatheter valve prosthesis 有权
公开(公告)号：US10828157B2
公开(公告)日：2020-11-10
申请号：US15448071
申请日：2017-03-02
申请人： HIGHLIFE SAS
发明人： Georg Börtlein , Malek Nasr
IPC分类号： A61F2/24 , A61F2/848
摘要： A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections. The tubular body is provided with a first plurality of projections which extend from the first or second body section in an axial direction of the tubular body and each of which has a free end arranged to overlap the outer circumferential groove. An elongate outer member may be disposed at the exterior of the connection channel wall structure at a level of the circumferential groove.

55. 发明申请

US20200046499A1 TREATMENT CATHETER MEMBER WITH ENCIRCLING FUNCTION 审中-公开
公开(公告)号：US20200046499A1
公开(公告)日：2020-02-13
申请号：US16598623
申请日：2019-10-10
申请人： HIGHLIFE SAS
发明人： Georg BORTLEIN , Malek NASR
IPC分类号： A61F2/24 , A61B17/00
摘要： A catheter member for interacting with a circumferential tissue structure includes: an elongate primary catheter having at least one inner lumen and extending along a longitudinal axis; first and second elongate secondary catheters, each having an inner lumen, and each positionable in an inner lumen of the primary catheter to be moveable relatively thereto and exposable therefrom; and a first flexing mechanism to provide a distal end portion of the first and/or second secondary catheter with a tendency to assume a first secondary bent shape. The distal end portion of the first and/or second secondary catheters is provided so as to be able to be flexed by the first flexing mechanism to form an arm portion substantially transverse to the direction of the longitudinal axis of the primary catheter so as to assume the first secondary bent shape when exposed from a distal end portion of the primary catheter.

56. 发明授权

US10195027B2 Transcatheter valve prosthesis 有权
公开(公告)号：US10195027B2
公开(公告)日：2019-02-05
申请号：US15343792
申请日：2016-11-04
申请人： HIGHLIFE SAS
发明人： Malek Nasr
IPC分类号： A61F2/24 , A61F2/82
摘要： A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end such that the outflow end includes a proximal section and a plurality of beams. The plurality of beams being disposed distally of the proximal section in an outflow direction. Additionally, the tubular body including struts with peaks and valleys at the inflow end of the tubular body such that the proximal section of the outflow end is disposed distally of the peaks and valleys in the outflow direction. Furthermore, the tubular body being configured such that movement of the proximal section of the outflow end radially inward causes the inflow end to flare radially outward, and an arrangement of the struts being configured such that movement of the peaks radially inward causes the valleys to flare radially outward.

57. 发明授权

US10188514B2 Transcatheter valve prosthesis 有权
公开(公告)号：US10188514B2
公开(公告)日：2019-01-29
申请号：US15343302
申请日：2016-11-04
申请人： HIGHLIFE SAS
发明人： Malek Nasr
IPC分类号： A61F2/24 , A61F2/82
摘要： A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The valve leaflet being supported by only two beams of the plurality of beams, and connection points linking the inflow end of the tubular body and the plurality of beams. A number of connection points being equivalent to a number of the valve leaflets. Additionally, each beam of the plurality of beams being directly connected to an adjacent beam so that the plurality of beams extends the entire circumferential length of the tubular body at the outflow end.

58. 发明申请

US20180125651A1 TRANSCATHETER VALVE PROSTHESIS 审中-公开
公开(公告)号：US20180125651A1
公开(公告)日：2018-05-10
申请号：US15343936
申请日：2016-11-04
申请人： HIGHLIFE SAS
发明人： Malek NASR
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2415 , A61F2/2457 , A61F2002/828 , A61F2220/0075 , A61F2230/001 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/0029 , A61F2250/0036 , A61F2250/0039 , A61F2250/0048
摘要： A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end, and the tubular body including a proximal-most end at the inflow end and a distal-most end at the outflow end. The tubular body including a plurality of arched beams at the outflow end of the tubular body such that the arched beams form the distal-most end of the tubular body. Connection points linking the inflow end of the tubular body and the arched beams, a number of connection points being equivalent to a number of the valve leaflets. Each arched beam being directly attached to an adjacent arched beam such that the arched beams are continuous along the entire circumference of the tubular body at the outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets.

59. 发明申请

US20180125648A1 TRANSCATHER VALVE PROSTHESIS 有权
公开(公告)号：US20180125648A1
公开(公告)日：2018-05-10
申请号：US15343359
申请日：2016-11-04
申请人： HIGHLIFE SAS
发明人： Malek NASR
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2415 , A61F2/2457 , A61F2002/828 , A61F2220/0075 , A61F2230/001 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0029 , A61F2250/0036 , A61F2250/0039 , A61F2250/0048
摘要： A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end and including a plurality of struts with at least one motion buffer component integrated in the tubular body. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed over an outer surface of the tubular body and over an outer surface of the motion buffer component. Additionally, when the outflow end of the tubular body moves radially inward from movement of the valve leaflets, the motion buffer component being configured so as to not move radially inward with the outflow end of the tubular body.

60. 发明申请

US20150257880A1 TRANSCATHETER VALVE PROSTHESIS 有权
公开(公告)号：US20150257880A1
公开(公告)日：2015-09-17
申请号：US14204394
申请日：2014-03-11
申请人： HIGHLIFE SAS
发明人： Georg BÖRTLEIN , Malek NASR
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2409 , A61F2002/8483 , A61F2220/0016 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： A system for implanting a heart valve that includes a radially self-expandable tubular body having an inflow end and a preformed groove disposed at an outer surface of the tubular body between the inflow end and the outflow end, wherein the preformed groove extends at least partially around the tubular body and having a circumferential opening facing radially outward of the tubular body. A valve may be disposed within and attached to the tubular body. Additionally, a trapping member may be configured to form at least a partial loop encircling the preformed groove so as to trap portions of native valve leaflets and/or chords in the preformed groove, the trapping member including one or more barbs.
摘要翻译：一种用于植入心脏瓣膜的系统，其包括具有流入端的径向自扩张管状体和设置在所述管状体的外表面处于所述流入端和所述流出端之间的预成形凹槽，其中所述预成型凹槽至少部分地延伸围绕管体并且具有面向管状体的径向外侧的周向开口。阀可以设置在管状体内并附接到管状体。另外，捕获构件可以被构造成形成环绕预定的凹槽的至少一个部分环，以便将预先形成的凹槽中的自然瓣叶和/或弦的部分捕获，所述捕获构件包括一个或多个倒钩。

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