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51. 发明申请

US20210260015A1 COMPOSITION FOR INHIBITING FAT ACCUMULATION 有权
公开(公告)号：US20210260015A1
公开(公告)日：2021-08-26
申请号：US17256785
申请日：2019-07-02
申请人： National University Corporation Tokyo University of Agriculture and Technology , THE FOOD SCIENCE INSTITUTE FOUNDATION , MEIJI CO., LTD.
发明人： Ikuo KIMURA , Daisuke KOZUTSUMI , Kinya ASHIDA , Kentaro NAKAMURA
IPC分类号： A61K31/23 , A61P3/04 , A23L33/12 , A23L33/00 , A23D9/00
摘要： An object of the present invention is to provide a novel composition for use in suppressing fat accumulation, a novel composition for use in suppressing body weight gain, and a composition for use in promoting the production of a ketone body. According to the present invention, there is provided a composition for use in suppressing fat accumulation, suppressing body weight gain and/or promoting the production of a ketone body, comprising, as an active ingredient, a medium chain fatty acid glyceride comprising a saturated fatty acid having 8 carbon atoms as a constituent fatty acid. The ratio of the amount of the saturated fatty acid having 8 carbon atoms to the total amount of medium chain fatty acids of the medium chain fatty acid glyceride can be set to 0.6 or more. The medium chain fatty acid glyceride may further comprise, as a constituent fatty acid, a saturated fatty acid having 10 carbon atoms and/or a saturated fatty acid having 12 carbon atoms. The medium chain fatty acid glyceride is preferably a medium chain fatty acid triglyceride.

52. 发明申请

US20210213077A1 A COMPOSITION FOR ENHANCING IMMUNE CHECKPOINT BLOCKADE THERAPY 有权
公开(公告)号：US20210213077A1
公开(公告)日：2021-07-15
申请号：US17058329
申请日：2019-06-13
申请人： MEIJI CO., LTD.
发明人： Hirotaka KAWANABE , Marie NAKAMURA
IPC分类号： A61K35/747 , A61K35/20 , A61P37/04
摘要： The object of the invention is to provide a composition for enhancing an immune checkpoint blockade therapy. A composition forenhancing an immune checkpoint blockade therapy, which contains an exopolysaccharide of a lactic acid bacterium is provided. Preferred examples of the lactic acid bacterium include Lactobacillus bacteria (especially Lactobacillus delbrueckii subsp. bulgaricus OLL1073 R-1).

53. 发明申请

US20210190732A1 SOLID-LIQUID DISTRIBUTION DETECTING APPARATUS 有权
公开(公告)号：US20210190732A1
公开(公告)日：2021-06-24
申请号：US16760230
申请日：2018-11-08
申请人： MEIJI CO., LTD.
发明人： Nobuyuki KONISHI
IPC分类号： G01N29/22 , B01D9/04 , G01N29/036 , G01N29/12 , G01N29/44
摘要： It is an object of the present invention is to obtain a solid-liquid distribution detecting apparatus that detects solid-liquid distribution in a solid-liquid separation column. A solid-liquid distribution detecting apparatus (20) of the present invention detects solid-liquid distribution of a content in a solid-liquid separation column (10) of a freeze concentration device and includes a sound source (21) that emits a sound wave to the column surface of the solid-liquid separation column (10), a measuring device (22) that measures a resonance waveform on the surface of the column, and an analysis device (24) that analyzes the resonance waveform measured by the measuring device (22) and determines a solid-liquid distribution state of the content in the solid-liquid separation column based on the analysis result.

54. 发明申请

US20200371036A1 METHOD FOR DETECTING PROTEIN 审中-公开
公开(公告)号：US20200371036A1
公开(公告)日：2020-11-26
申请号：US16762653
申请日：2018-11-09
申请人： MEIJI CO., LTD.
发明人： Akihiro NAKAJIMA , Keiko MORIKUBO
IPC分类号： G01N21/78 , G01N33/08 , G01N33/04 , G01N21/25 , G01N33/12
摘要： An object of the present invention is to provide a simple method of detecting a protein in a liquid, which requires less labor or cost as compared with a conventional method. In the present invention, it has been found that coloring a protein by a color reaction specific to the protein, performing filtration using a filter which easily adsorbs a protein to concentrate the protein on the filter, and checking coloration allows for simply and easily detecting and measuring a protein. In addition, it has been found that filtering a protein using a filter, concentrating the protein on the filter, then coloring the protein by a color reaction specific to the protein, and checking the protein allows simply and easily detecting and measuring a protein.

55. 发明申请

US20200088735A1 DEVICE FOR MONITORING EFFECTIVE STATE OF KETOGENIC DIET 审中-公开
公开(公告)号：US20200088735A1
公开(公告)日：2020-03-19
申请号：US16494864
申请日：2018-04-06
申请人： MEIJI CO., LTD.
发明人： Kinya ASHIDA
IPC分类号： G01N33/64 , G01N33/497
摘要： The purpose of the present invention is to provide a ketogenic diet monitoring device for managing the effective state of a ketogenic diet for an animal individually. The ketogenic diet monitoring device of the present invention has a configuration in which the amount of metabolite in gases carried from the inside to the outside of the body of an animal for which the effective state of a ketogenic diet is being managed is measured once and/or a plurality of times over time and monitored.

56. 发明申请

US20190307141A1 LACTIC ACID BACTERIAL FERMENTATION PROMOTING AGENT 审中-公开
公开(公告)号：US20190307141A1
公开(公告)日：2019-10-10
申请号：US16309565
申请日：2017-06-16
申请人： MEIJI CO., LTD.
发明人： Keisuke FURUICHI , Emi TOYAMA
IPC分类号： A23C9/13 , A23C9/123
摘要： The present invention provides a lactic acid bacterial fermentation-promoting agent and a fermentation method suitable for use in food production. The present invention relates to a fermentation promoting agent for a lactic acid bacterium, having a compound having a purine skeleton with a hydrogen atom attached to the carbon atom at position 2, and a method for promoting fermentation for a lactic acid bacterium using the same and a method for producing a fermented food such as fermented milk.

57. 发明申请

US20190201460A1 ANTICARIOGENIC AGENT AND ANTICARIOGENIC COMPOSITION 审中-公开
公开(公告)号：US20190201460A1
公开(公告)日：2019-07-04
申请号：US16353678
申请日：2019-03-14
申请人： Meiji Co., Ltd.
发明人： Masaki TERAHARA , Takeshi TAKAHASHI , Hiroyuki ITOU
IPC分类号： A61K35/745 , A61K9/16 , A23L33/135 , C12N1/20 , A61Q11/00 , A61K47/36 , A61K8/99
CPC分类号： A61K35/745 , A23L33/135 , A23V2002/00 , A61K8/99 , A61K9/16 , A61K47/36 , A61Q11/00 , C12N1/20
摘要： The present invention provides a novel anticariogenic agent without side effects so that anticariogenic effect can also be obtained in humans who are highly sensitive to oligosaccharides and sugar alcohols. Also, an agent for preventing periodontal disease or for treating periodontal disease which has an effect of preventing or treating periodontal disease and which does not have side effects is provided. The invention relates to an anticariogenic agent and an anticariogenic composition comprising a bifidobacterium, an agent and a composition for preventing periodontal disease comprising a bifidobacterium and an agent and a composition for treating periodontal disease comprising a bifidobacterium.

58. 发明申请

US20190201459A1 ANTI-ALLERGIC AGENT FOR INFANTS 审中-公开
公开(公告)号：US20190201459A1
公开(公告)日：2019-07-04
申请号：US16353135
申请日：2019-03-14
申请人： Meiji Co., Ltd. , SHIGA UNIVERSITY OF MEDICAL SCIENCE
发明人： Shigeki Koshida , Masaki Terahara
IPC分类号： A61K35/745 , A61K35/74 , A23L33/135 , A61K9/00 , A23L33/00 , A61K47/36 , A61P37/08
CPC分类号： A61K35/745 , A23L33/135 , A23L33/40 , A23V2002/00 , A23V2200/304 , A23V2250/5114 , A23Y2300/25 , A61K9/0053 , A61K9/0095 , A61K35/74 , A61K47/36 , A61P37/08
摘要： Provided herein is an anti-allergic agent for ameliorating an allergic disease in infants, particularly newborns, without causing side effects. The anti-allergic agent for infants comprises a bifidobacterium.

59. 发明申请

US20190134114A1 Composition for Improving Brain Function for Neonates 审中-公开
公开(公告)号：US20190134114A1
公开(公告)日：2019-05-09
申请号：US16092778
申请日：2017-04-12
申请人： MEIJI CO., LTD.
发明人： Satoshi KUSUDA , Satsuki TOTSU , Masaki TERAHARA
IPC分类号： A61K35/745 , A23L33/135 , A23L33/00
摘要： An object of the present invention is to provide a brain function improving agent for neonates, especially, newborn neonates. According to the present invention, there is provided a brain function improving agent for neonates, comprising a lactic acid bacterium and/or a Bifidobacterium. The brain function improving agent or composition for improving brain function for neonates according to the present invention is advantageous in that the use thereof can improve the developmental quotient without any side effect and also enables effective development and growth of neonates.

60. 发明授权

US10049602B2 Swallowing simulation apparatus and method 有权
公开(公告)号：US10049602B2
公开(公告)日：2018-08-14
申请号：US14387531
申请日：2013-03-18
申请人： Meiji Co., Ltd. , Yukihiro Michiwaki
发明人： Yukihiro Michiwaki , Keigo Hanyuu , Tetsu Kamiya , Yoshio Toyama , Rika Murakami
IPC分类号： G09B23/32 , G09B23/28 , G09B23/30 , G06T17/00 , A61C19/045 , A61C11/00 , A61B5/00
摘要： A swallowing simulation apparatus that facilitate approximately reproducing an actual phenomenon of swallowing and allows quantifying a physical quantity related to a behavior and a physical property of an orally-ingested product is provided. The swallowing simulation apparatus 100A comprises a head-and-neck modeling unit 10 configured to form a dynamic three-dimensional model of the head-and-neck 10a that includes head-and-neck organs, an organ movement setting unit 30 configured to set movements of the respective head-and-neck organs in the dynamic three-dimensional model of the head-and-neck, an orally-ingested-product physical-property setting unit 40 configured to set an orally-ingested product as an analysis target and a physical property of the orally-ingested product, an input unit 81 configured to input a pseudo-orally-ingested product 20 formed by modeling the orally-ingested product to an oral cavity, a movement analysis unit 50 configured to analyze the movements of the respective head-and-neck organs in the dynamic three-dimensional model of the head-and-neck 10a and a behavior of the pseudo-orally-ingested product 20 during swallowed in a three-dimensional space using a particle method, and a display unit 82 configured to display an analysis result of the movements of the respective head-and-neck organs and the behavior of the pseudo-orally-ingested product during swallowed that are analyzed by the movement analysis unit 50 on a movement screen.

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