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41. 发明授权

US07507582B2 Method and device for multicolour 2-photon fluorescence coincidence analysis 有权
标题翻译：多色双光子荧光重合分析方法与装置
公开(公告)号：US07507582B2
公开(公告)日：2009-03-24
申请号：US10333034
申请日：2001-07-18
申请人： Katrin Heinze , Petra Schwille , Andre Koltermann , Ulrich Kettling
发明人： Katrin Heinze , Petra Schwille , Andre Koltermann , Ulrich Kettling
IPC分类号： G01N21/64
CPC分类号： G01N21/6408 , B82Y10/00 , B82Y20/00 , G01J2003/2866 , G01N2021/6441 , Y10T436/13
摘要： A method of fluorescence measurement on analytes, marked with different fluorescent markers, which have spectrally different fluorescence emissions, in a sample is described, having the following steps: illumination of the sample in the measurement volume using a laser to excite the fluorescence emission of the at least two fluorescent markers, the illumination of the measurement volume being performed with a maximum of one single laser line, having an excitation intensity sufficiently high that the fluorescent markers are jointly excited through 2-photon absorptions, detection of the fluorescence emission using at least two detector devices which are designed for light detection in different spectral ranges in accordance with the spectral fluorescence properties of the fluorescent markers, and performance of a cross-correlation and/or coincidence analysis of detector signals of the detector devices. A measurement device for performing the method is also described.
摘要翻译：描述了在样品中具有不同荧光标记的分析物上荧光测量的方法，所述分析物具有不同的荧光发射，具有以下步骤：使用激光照射测量体积中的样品以激发荧光发射至少两个荧光标记物，用最大量的一条单一激光线照射测量体积，具有足够高的激发强度，使得荧光标记物通过双光子吸收共同激发，至少使用至少检测荧光发射两个检测器装置被设计用于根据荧光标记的光谱荧光特性在不同光谱范围内进行光检测，以及执行检测器装置的检测器信号的互相关和/或重合分析。还描述了用于执行该方法的测量装置。

42. 发明申请

US20090051910A1 Calibration reference light source and calibration system using the same 有权
标题翻译：校准参考光源和校准系统使用相同
公开(公告)号：US20090051910A1
公开(公告)日：2009-02-26
申请号：US12229171
申请日：2008-08-20
申请人： Kenji Imura
发明人： Kenji Imura
IPC分类号： G01J3/02
CPC分类号： G01J3/10 , G01J3/0254 , G01J3/28 , G01J2003/104 , G01J2003/2866
摘要： In a calibration reference light source and a sensitivity calibration system using the same, a plurality of single-wavelength light sources for emitting reference lights having mutually different single-wavelengths are used instead of a black body radiation source for radiating a white light, and not only the intensities of the single-wavelength reference lights, but also the wavelengths thereof are measured to obtain sensitivity correction coefficients of intensity-to-radiance conversion data. Thus, obtained reference radiance are highly reliable and sensitivity correction of spectrophotometers and spectral illuminometers can be performed with high accuracy and reliability at a user side, whereby the calibration reference light source and the calibration system using the same can be obtained at low cost.
摘要翻译：在校准基准光源和使用其的灵敏度校准系统中，使用用于发射具有相互不同的单一波长的参考光的多个单波长光源代替用于发射白光的黑体辐射源，而不是仅测量单波长参考光的强度，还测量其波长，以获得强度到辐射转换数据的灵敏度校正系数。因此，获得的基准亮度高度可靠，并且可以在用户侧以高精度和可靠性执行分光光度计和光谱照度计的灵敏度校正，由此可以以低成本获得校准参考光源和使用其的校准系统。

43. 发明授权

US07496391B2 Manual and automatic probe calibration 有权
标题翻译：手动和自动探头校准
公开(公告)号：US07496391B2
公开(公告)日：2009-02-24
申请号：US10757279
申请日：2004-01-13
申请人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
发明人： Mohamed Kheir Diab , Massi E. Kiani , Charles Robert Ragsdale , James M. Lepper, Jr.
IPC分类号： A61B5/145
CPC分类号： A61B5/1495 , A61B5/0205 , A61B5/02427 , A61B5/14552 , A61B5/6826 , A61B5/6838 , A61B2562/08 , G01J3/02 , G01J3/0254 , G01J3/027 , G01J3/0275 , G01J3/0291 , G01J3/10 , G01J2003/2866 , G01N21/255 , G01N21/274 , G01N21/31 , G01N21/3151 , G01N21/39 , G01N2021/3144 , G01N2201/0627
摘要： Embodiments of the present disclosure include an oximeter sensor system including a reusable portion including a substantially rigid connector connected to an end of a cable. The substantially rigid connector includes an electronic element housing at least one electronic component of a probe. The system also includes a disposable portion including a flexible wrap comprising a substantially rigid connection port shaped to receive the substantially rigid connector in a releasably securable manner.
摘要翻译：本公开的实施例包括血氧计传感器系统，其包括可重复使用部分，其包括连接到电缆端部的基本上刚性的连接器。基本刚性的连接器包括容纳探针的至少一个电子部件的电子元件。该系统还包括一次性部分，其包括柔性包装，其包括基本上刚性的连接端口，其形状为以可释放地固定的方式容纳基本上刚性的连接器。

44. 发明授权

US07339665B2 Calibration source for calibrating spectroradiometer, calibration method using the same, and calibration system 有权
标题翻译：用于校准光谱辐射计的校准源，使用其的校准方法和校准系统
公开(公告)号：US07339665B2
公开(公告)日：2008-03-04
申请号：US11303313
申请日：2005-12-16
申请人： Kenji Imura
发明人： Kenji Imura
IPC分类号： G01J3/02 , G01J3/18
CPC分类号： G01J5/522 , G01J3/28 , G01J2003/2866
摘要： A spectroradiometer is calibrated by a calibration source including a plurality of monochromatic sources for emitting monochromatic rays having different wavelengths from each other, respectively; a reference light emitter for emitting monochromatic reference light by receiving the monochromatic rays emitted from the monochromatic sources; a reference sensor for measuring a reference intensity of the monochromatic reference light emitted from the reference light emitter; and a controller for controlling the emission of the monochromatic rays by the monochromatic sources, and the measurement of the reference intensity of the monochromatic reference light by the reference sensor.
摘要翻译：分光辐射计通过校准源校准，校准源包括分别用于发射彼此具有不同波长的单色光的多个单色光源; 参考光发射器，用于通过接收从单色源发出的单色射线发射单色参考光; 用于测量从参考光发射器发射的单色参考光的参考光强度的参考传感器; 以及用于控制单色光源发射单色光的控制器，以及由基准传感器测量单色参考光的参考光强度。

45. 发明授权

US07280251B1 System and method for calibrating color printers 有权
标题翻译：校准彩色打印机的系统和方法
公开(公告)号：US07280251B1
公开(公告)日：2007-10-09
申请号：US10880075
申请日：2004-06-29
申请人： Richard A. Holub
发明人： Richard A. Holub
IPC分类号： H04N1/40
CPC分类号： G01J3/02 , G01J3/0202 , G01J3/0218 , G01J3/0262 , G01J3/0264 , G01J3/0272 , G01J3/0289 , G01J3/0291 , G01J3/18 , G01J3/28 , G01J3/46 , G01J3/462 , G01J3/463 , G01J3/465 , G01J3/50 , G01J3/506 , G01J3/524 , G01J2003/2866 , G01J2003/466 , G01N21/274 , G03B27/547 , G09G5/02 , G09G2320/0276 , G09G2320/043 , G09G2320/0606 , G09G2320/0626 , G09G2320/066 , G09G2320/0666 , H04N1/603 , H04N1/6052 , H04N9/3182 , H04N9/3194
摘要： A system and method for calibrating color printers, and related particularly to, a system and method for calibrating color printers over a network utilizing a profile server (representing a networkable computer server system) which provides color transformations in accordance with printer configurations having at least information read from consumable ink or toner cartridges for such printers. Such color transformations enable different color printers, or even the same color printer with different printer configurations, to render color consistently.
摘要翻译：一种用于校准彩色打印机的系统和方法，特别涉及一种通过网络校准彩色打印机的系统和方法，该配置文件服务器（代表可联网计算机服务器系统）根据具有至少信息的打印机配置提供颜色变换从这种打印机的耗材墨水或碳粉盒中读取。这种颜色转换使得不同的彩色打印机，甚至是具有不同打印机配置的相同彩色打印机能够一致地呈现颜色。

46. 发明申请

US20070183781A1 Broad-and inter-band multi-wavelength-reference method and apparatus for wavelength measurement or monitoring systems 有权
标题翻译：用于波长测量或监测系统的宽带和带间多波长参考方法和装置
公开(公告)号：US20070183781A1
公开(公告)日：2007-08-09
申请号：US11329522
申请日：2006-01-10
申请人： Ke-Cai Zeng
发明人： Ke-Cai Zeng
IPC分类号： H04J14/02
CPC分类号： H04J14/0227 , G01J3/26 , G01J3/28 , G01J9/0246 , G01J2003/2866 , H04B10/07957 , H04J14/0278
摘要： A wavelength measurement or monitoring system provides a tunable Fabry-Perot optical filter. At least one known light source is used to calibrate and correlate separate wavelength bands scanned by the tunable Fabry-Perot optical filter. At least one wavelength reference is utilized to calibrate at least one wavelength band of the tunable Fabry-Perot optical filter. The wavelength reference is transferred to a wavelength band that is identified for measurement when the wavelength reference is not in a wavelength band identified for measurement by the tunable Fabry-Perot optical filter. An unknown optical signal is scanned through the tunable Fabry-Perot optical filter. The wavelengths in the unknown optical signal are specified.
摘要翻译：波长测量或监测系统提供可调谐的法布里 - 珀罗滤光器。使用至少一个已知的光源来校准和关联由可调谐法布里 - 珀罗滤光器扫描的分离的波长带。使用至少一个波长参考来校准可调谐法布里 - 珀罗滤光器的至少一个波长带。当波长参考不在被可调谐法布里 - 珀罗滤光器测量的波长带中时，波长参考被传送到被识别用于测量的波长带。通过可调谐法布里 - 珀罗滤光片扫描未知的光信号。指定未知光信号中的波长。

47. 发明申请

US20070159638A1 OPTICAL SIGNAL MEASUREMENT SYSTEM 失效
标题翻译：光信号测量系统
公开(公告)号：US20070159638A1
公开(公告)日：2007-07-12
申请号：US11615986
申请日：2006-12-24
申请人： Ke-Cai Zeng , Paul Chang , Jurgen Brendel
发明人： Ke-Cai Zeng , Paul Chang , Jurgen Brendel
IPC分类号： G01B9/02
CPC分类号： G01J3/26 , G01J3/02 , G01J3/0286 , G01J3/28 , G01J2003/2866 , G01M11/331 , G01M11/336 , G01M11/338 , H04B10/07951
摘要： An optical signal measurement system provides a tunable optical filter. An unknown optical signal is scanned through the tunable optical filter. The wavelength and chromatic dispersion values of the unknown optical signal scanned through the tunable optical filter are measured by operating the tunable optical filter in a scanning mode for at least one of OSA and PMD measurements, and in a stepping mode for CD measurements. The wavelength and the dispersion values in the unknown optical signal are specified.
摘要翻译：光信号测量系统提供可调光滤波器。通过可调光滤波器扫描未知的光信号。通过可调谐滤光器扫描的未知光信号的波长和色散值通过以扫描模式对OSA和PMD测量中的至少一个进行操作，并以用于CD测量的步进模式来测量。指定未知光信号中的波长和色散值。

48. 发明申请

US20070145258A1 Method and apparatus for automated spectral calibration 审中-公开
标题翻译：用于自动光谱校准的方法和装置
公开(公告)号：US20070145258A1
公开(公告)日：2007-06-28
申请号：US11640197
申请日：2006-12-18
申请人： Matthew Nelson , Patrick Treado
发明人： Matthew Nelson , Patrick Treado
IPC分类号： G01D18/00
CPC分类号： G01J3/28 , A61B5/0059 , A61B2560/0223 , G01J2003/2866
摘要： The disclosure generally relates to a method and apparatus for automated spectral calibration of a spectroscopy device. In one embodiment, the disclosure relates to a method for simultaneous calibration and spectral imaging of a sample by: simultaneously illuminating the sample and a calibrant with a plurality of illuminating photons; receiving, at the spectrometer, a first plurality of photons collected from the sample and a second plurality of photons collected from the calibrant; forming a calibrant spectrum from the first plurality of collected photons and a sample spectrum from the second plurality of collected photons; comparing the calibrant spectrum with a reference spectrum of the calibrant to determine a wavelength-shift in the calibrant spectrum; applying the wavelength-shift to the sample spectrum to obtain a calibrated sample spectrum.
摘要翻译：本发明一般涉及一种用于光谱设备的自动光谱校准的方法和装置。在一个实施方案中，本公开涉及通过以下步骤同时校准和光谱成像的方法：同时用多个照明光子照射样品和校准物; 在光谱仪处接收从样品收集的第一组多个光子和从校准物收集的第二组多个光子; 从所述第一多个收集的光子形成校准谱，以及来自所述第二多个收集的光子的样品光谱; 将校准谱与校准物的参考光谱进行比较，以确定校准谱中的波长漂移; 将波长偏移应用于样本光谱以获得校准的样本光谱。

49. 发明申请

US20070064230A1 Broadband laser spectroscopy 审中-公开
标题翻译：宽带激光光谱仪
公开(公告)号：US20070064230A1
公开(公告)日：2007-03-22
申请号：US11233436
申请日：2005-09-21
申请人： Warren Harper , Richard Williams
发明人： Warren Harper , Richard Williams
IPC分类号： G01J3/28
CPC分类号： G01J3/10 , G01J3/12 , G01J2003/2866 , G01N21/3504 , G01N21/39 , G01N2021/1793 , G01N2021/3513 , G01N2021/399
摘要： Apparatus and processes for chemical sensing are disclosed. Embodiments of the present invention comprise a laser device producing a broadband spectral output that can interact with a sample, a wavelength dispersive element, and a detector. The width of the broadband spectral output is greater than or approximately equal to the width of a spectral feature of the sample. The wavelength dispersive element can resolve the broadband spectral output after the broadband spectral output has had an interaction with the sample. The detector detects the intensity of the wavelength-resolved broadband spectral output.
摘要翻译：公开了用于化学感测的装置和方法。本发明的实施例包括产生可与样品，波长色散元件和检测器相互作用的宽带光谱输出的激光器件。宽带频谱输出的宽度大于或近似等于样本的光谱特征的宽度。波长色散元素可以在宽带频谱输出与样本相互作用后解析宽带频谱输出。检测器检测波长分辨的宽带光谱输出的强度。

50. 发明授权

US07180601B1 Optical system featuring chirped Bragg grating etalon for providing precise reference wavelengths 有权
标题翻译：具有啁啾Bragg光栅标准具的光学系统，用于提供精确的参考波长
公开(公告)号：US07180601B1
公开(公告)日：2007-02-20
申请号：US09703823
申请日：2000-11-01
申请人： Michael A. Davis , David R. Fournier
发明人： Michael A. Davis , David R. Fournier
IPC分类号： G01B9/02
CPC分类号： G01J3/18 , G01J3/1895 , G01J2003/2866
摘要： An optical system has a broadband source and a chirped Bragg grating etalon. In operation, the broadband source provides a broadband optical signal. The chirped Bragg grating etalon responds to the broadband optical signal, for providing a chirped Bragg grating etalon optical signal having a precise set of the optical reference signals. The chirped Bragg grating etalon may include a pair of chirped Bragg gratings. The precise set of the optical reference signals is determined by the spacing of the chirped Bragg gratings of the chirped Bragg grating etalon. The precise set of the optical reference signals includes a series of peaks covering most of a source spectral width of the broad optical source signal with the power at the beginning and end of the spectrum passed unaffected by the chirped Bragg grating etalon due to the limited bandwidth thereof.
摘要翻译：光学系统具有宽带源和啁啾布拉格光栅标准具。在操作中，宽带源提供宽带光信号。啁啾的布拉格光栅标准具响应宽带光信号，用于提供具有精确的一组光参考信号的啁啾布拉格光栅标准具光信号。啁啾的布拉格光栅标准具可以包括一对啁啾的布拉格光栅。光学参考信号的精确集合由啁啾布拉格光栅标准具的啁啾布拉格光栅的间隔确定。光学参考信号的精确集合包括覆盖宽光源信号的大部分源光谱宽度的一系列峰值，其中光谱开始和结束处的功率不受啁啾布拉格光栅标准具的影响，由于有限的带宽其中。

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