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41. 发明申请

US20110166413A1 COMPLIANT CARDIAC SUPPORT DEVICE 审中-公开
标题翻译：合规心脏辅助装置
公开(公告)号：US20110166413A1
公开(公告)日：2011-07-07
申请号：US13049499
申请日：2011-03-16
申请人： Clifton A. ALFERNESS , Donald G. ROHRBAUGH , James Edward SHAPLAND , Michael J. GIRARD , Donald F. PALME, II , James E. COX
发明人： Clifton A. ALFERNESS , Donald G. ROHRBAUGH , James Edward SHAPLAND , Michael J. GIRARD , Donald F. PALME, II , James E. COX
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , Y10S623/904
摘要： A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译：生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积，以将其插入体积中并使护套滑过心脏。护套具有在上下端之间的纵向尺寸，足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端。护套适于固定在心脏上，护套至少围绕瓣膜环和心室下肢。护套在心脏上是可调节的，以贴合地符合心脏的外部几何形状，并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张，并允许心脏收缩期间不受阻碍的收缩。

42. 发明授权

US07914438B2 Ventricular restoration patch 失效
标题翻译：心室恢复补片
公开(公告)号：US07914438B2
公开(公告)日：2011-03-29
申请号：US12568573
申请日：2009-09-28
申请人： Gerald D. Buckberg , Constantine L. Athanasuleas
发明人： Gerald D. Buckberg , Constantine L. Athanasuleas
IPC分类号： A61F2/00
CPC分类号： A61F2/2478 , A61F2/2445 , A61F2/2481 , A61F2/2487
摘要： A ventricular patch to restore the ventricular architecture of the heart includes a sheet of biocompatible material having a generally oval configuration, and a continuous ring fixed to the sheet. The ring has a generally oval configuration similar to the generally oval configuration of the sheet of biocompatible material. The ring defines a central generally oval region of the patch inside the ring and a circumferential region of the patch outside of the ring. The central generally oval region has a major axis and a minor axis. The ratio of the major axis to the minor axis is about 4:1.
摘要翻译：恢复心脏心室结构的心室贴片包括具有大致椭圆形构造的生物相容性材料片，以及固定在片材上的连续环。环具有类似于生物相容性材料片的大致椭圆形构造的大致椭圆形构造。环限定环内的贴片的中央大致椭圆形的区域以及环外的贴片的周边区域。中心的大致椭圆形区域具有长轴和短轴。长轴与短轴的比例约为4：1。

43. 发明申请

US20100268019A1 CADIAC SUPPORT DEVICE DELIVERY TOOL WITH INDEPENDENTLY MOVABLE ARMS 有权
标题翻译： CADIAC支持设备交付工具，具有独立可移动的ARMS
公开(公告)号：US20100268019A1
公开(公告)日：2010-10-21
申请号：US12764508
申请日：2010-04-21
申请人： Aaron J. HJELLE , Paul A. PIGNATO , Robert G. WALSH , William E. COHN , Ann Margaret THOMAS
发明人： Aaron J. HJELLE , Paul A. PIGNATO , Robert G. WALSH , William E. COHN , Ann Margaret THOMAS
IPC分类号： A61B17/00
CPC分类号： A61F2/2481 , A61B2017/00243 , A61B2017/22035 , A61B2017/2215 , A61F2002/2484
摘要： A device for delivery of a cardiac support device for treating cardiac disease of a heart includes a multistage deployment mechanism and an actuating mechanism for controlling the positions of the deployment mechanism. The deployment mechanism is operable to change between a retracted state and an extended state, and includes a plurality of independent stages, including, in one embodiment, a first stage including a guide structure for location adjacent a portion of the patient's heart when in the extended state. A second stage is movably coupled to the first stage, and is guided by the guide structure between the retracted and extended states. The second stage further releasably engages and supports the cardiac support device and positions the cardiac support device at the desired implantation location, guided by the guide structure of the stage. In some embodiments, the deployment mechanism may include additional stages. The actuating mechanism drives the deployment mechanism between the retracted and extended states, and independently controls the positions of the multiple stages of the deployment mechanism.
摘要翻译：用于递送用于治疗心脏心脏病的心脏支持装置的装置包括多级部署机构和用于控制部署机构的位置的致动机构。展开机构可操作以在缩回状态和延伸状态之间改变，并且包括多个独立的台阶，在一个实施例中，包括用于在延伸的患者的心脏的一部分附近定位的引导结构的第一阶段州。第二级可移动地联接到第一级，并且由引导结构在缩回状态和伸出状态之间引导。第二阶段进一步可释放地接合和支撑心脏支持装置，并且将心脏支持装置定位在期望的植入位置，并由舞台的引导结构引导。在一些实施例中，展开机构可以包括附加阶段。致动机构在缩回状态和伸展状态之间驱动展开机构，并且独立地控制展开机构的多个阶段的位置。

44. 发明申请

US20100152531A1 IMPLANTABLE MEDICAL DEVICE FOR DRUG DELIVERY AND METHOD OF USE 审中-公开
标题翻译：用于药物递送的可植入医疗装置和使用方法
公开(公告)号：US20100152531A1
公开(公告)日：2010-06-17
申请号：US12634974
申请日：2009-12-10
申请人： Amy M. Goodman , Peter M. Martin , William Mavity , Russell Ivanhoe , Matthew G. Fishler , Craig Mar
发明人： Amy M. Goodman , Peter M. Martin , William Mavity , Russell Ivanhoe , Matthew G. Fishler , Craig Mar
IPC分类号： A61M31/00 , A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484 , A61F2250/0067 , A61L31/10 , A61L31/16 , A61N1/0597 , A61N1/3627
摘要： An apparatus and method of preparing a cardiac harness for use in controllably delivering a medicament such as an mTOR inhibitor or aldosterone blockade from the surface of the cardiac harness to the epicardium of a patient's heart for the site-specific treatment of cardiac and non-cardiac maladies. The delivery of the medicament from the cardiac harness is achieved by: coating the medicament on the surface of the cardiac harness; coating the cardiac harness with a polymer material or dielectric material and impregnating the coating with the medicament; or by loading the medicament into an implant attached to the cardiac harness.
摘要翻译：一种制备心脏线束的装置和方法，用于可控地将诸如mTOR抑制剂或醛固酮阻断剂的药物从心脏线束的表面输送到患者心脏的心外膜用于心脏和非心脏的位点特异性治疗疟疾通过以下方式实现药物从心脏线束的输送：在心脏线束的表面上涂覆药物; 用聚合物材料或介电材料涂覆心脏线束并用药物浸渍该涂层; 或通过将药物装载到附接到心脏线束的植入物中。

45. 发明授权

US07736299B2 Introducer for a cardiac harness delivery 失效
标题翻译：导管员用于心脏线束传送
公开(公告)号：US07736299B2
公开(公告)日：2010-06-15
申请号：US11187276
申请日：2005-07-21
申请人： Alan Klenk , Joshua Wallin
发明人： Alan Klenk , Joshua Wallin
IPC分类号： A61M29/00
CPC分类号： A61B17/00234 , A61B2017/00238 , A61B2017/00243 , A61B2017/00247 , A61B2017/308 , A61B2018/00392 , A61F2/2481 , A61F2002/2484
摘要： A system for creating a passage through the pericardium of a patient to permit access of a cardiac harness delivery device, including a tubular introducer sleeve and a tubular dilator sleeve insertable into the introducer sleeve. The introducer sleeve has a slot and a distal portion biased in a reduced opening. The distal end being positioned within an incision through the pericardium. Insertion of the dilator sleeve into the introducer sleeve causes it to push outwardly against the reduced opening, thereby expanding the reduced opening of the introducer sleeve sufficiently to permit a cardiac harness delivery device to access the epicardium. The introducer sleeve is releasably locked to the dilator sleeve by operation of a slot on the introducer sleeve and a protrusion on the dilator sleeve, which slides within the slot. The slot has detents that releasably lock the dilator sleeve at alternative positions within the introducer sleeve, thereby maintaining the reduced opening or, alternatively, the expanded opening to facilitate operation of a cardiac harness delivery device.
摘要翻译：一种用于创建穿过患者心包通道的系统，以允许进入心脏线束输送装置，包括管状导引器套筒和可插入导引套筒的管状扩张器套筒。引导器套筒具有狭槽和偏置在减小的开口中的远端部分。远端位于穿过心包的切口内。将扩张器套筒插入引导器套筒中使其向外推动减小的开口，从而充分地扩大导引套筒的减小的开口，以允许心脏线束递送装置进入心外膜。引导器套筒通过操作导引器套管上的狭缝和扩张器套筒上的突起而可释放地锁定到扩张器套筒，该突起部在狭槽内滑动。狭槽具有可释放地将扩张器套管锁定在引导器套筒内的替代位置处的棘爪，从而保持减小的开口，或者替换地，扩张开口以便于心脏线束递送装置的操作。

46. 发明申请

US20100137678A1 SELF-ADJUSTING ATTACHMENT STRUCTURE FOR A CARDIAC SUPPORT DEVICE 审中-公开
标题翻译：自我调节辅助设备的附件结构
公开(公告)号：US20100137678A1
公开(公告)日：2010-06-03
申请号：US12701302
申请日：2010-02-05
申请人： Robert G. WALSH , Aaron J. HJELLE , Paul Andrew PIGNATO , Ann Margaret THOMAS , Hani N. SABBAH , Noreen Walen THOMPSON , Holly J. HICKS
发明人： Robert G. WALSH , Aaron J. HJELLE , Paul Andrew PIGNATO , Ann Margaret THOMAS , Hani N. SABBAH , Noreen Walen THOMPSON , Holly J. HICKS
IPC分类号： A61F2/00
CPC分类号： A61F2/2481
摘要： A cardiac support device including a jacket and elastic attachment structure for self-securing the jacket to a heart. The attachment structures can include undulating metal and polymer elements, a silicone band and elastomeric filaments on a base end of the jacket.
摘要翻译：一种心脏支持装置，包括用于将夹套自身固定到心脏的护套和弹性附接结构。附接结构可以包括起伏的金属和聚合物元件，硅胶带和在护套的基端上的弹性纤维。

47. 发明申请

US20100036194A1 METHOD AND DEVICE FOR DEPLOYMENT OF A SUB-PERICARDIAL SACK 有权
标题翻译：用于分配子囊袋的方法和装置
公开(公告)号：US20100036194A1
公开(公告)日：2010-02-11
申请号：US12578280
申请日：2009-10-13
申请人： Timothy G. Dietz , Eugene L. Timperman
发明人： Timothy G. Dietz , Eugene L. Timperman
IPC分类号： A61B17/00
CPC分类号： A61F2/2481 , A61F2002/2484
摘要： Various methods and devices for deploying a sub-pericardial sack about at least a portion of a heart to alleviate congestive heart failure. A medical device housing the sub-pericardial sack is inserted into the pericardial sack. An inverted umbrella framework is deployed through the medical device and into the pericardial sack to position the sub-pericardial sack adjacent the heart. The umbrella framework is then retracted through the medical device once the cardiac assist device is placed adjacent the heart. A steerable catheter can instead be deployed through the pericardial sack to deploy and position a cardiac assist device, such as a mesh, around the heart. The steerable catheter is covered by a sheath housing the cardiac assist device. Once the sheath is pulled back, the cardiac assist device is deployed and secured adjacent the heart. Filaments or tensions wires are used to tighten the mesh around the heart.
摘要翻译：用于部署围绕心脏的至少一部分的心包心包以减轻充血性心力衰竭的各种方法和装置。容纳心包心包的医疗装置插入心包中。通过医疗装置部署一个倒置的伞形框架，并将其放入心包中，将心包旁边的心包放置在心脏附近。一旦将心脏辅助装置放置在心脏附近，则伞形框架然后通过医疗装置缩回。可引导导管可以通过心包进行部署，以在心脏周围部署和定位心脏辅助装置，例如网状物。可导向的导管由容纳心脏辅助装置的护套覆盖。一旦护套被拉回，心脏辅助装置被部署并固定在心脏附近。长丝或紧张线用于收紧心脏周围的网状物。

48. 发明授权

US07641608B1 Sectional cardiac support device and method of delivery 有权
标题翻译：截面心脏支持装置及分娩方法
公开(公告)号：US07641608B1
公开(公告)日：2010-01-05
申请号：US11535251
申请日：2006-09-26
申请人： Joseph M Ruggio
发明人： Joseph M Ruggio
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484 , A61F2250/006 , A61F2250/0071
摘要： A cardiac support device formed from a plurality of compliant sections individually delivered and deployed at positions around the heart and interconnected to one another.
摘要翻译：由多个顺应性部分形成的心脏支持装置，其单独地递送和展开在心脏周围的位置并彼此互连。

49. 发明申请

US20090299133A1 VENTRICULAR INFARCT ASSIST DEVICE AND METHODS FOR USING IT 审中-公开
标题翻译：静脉注射辅助装置及其使用方法
公开(公告)号：US20090299133A1
公开(公告)日：2009-12-03
申请号：US12541112
申请日：2009-08-13
申请人： Hanson S. Gifford, III , Bernard H. Andreas
发明人： Hanson S. Gifford, III , Bernard H. Andreas
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , A61B17/00234 , A61B17/0401 , A61B2017/0419
摘要： This relates to surgical devices and methods of using them. In particular, the devices are used to support and to reform myocardial tissue in the region of and across an infarct. The devices provide tension across the infarct in varying degrees by attachment of the device to the myocardium at sites adjacent the infarct. A support-providing component across the infarct, between the heart attachment sites, provides support to the myocardial wall and support across the infarct. Optionally, but preferably, the support-providing component includes a time-delay element that variously may allow the device to be introduced onto the myocardial surface and to change the support of the support element over time.
摘要翻译：这涉及手术装置和使用它们的方法。特别地，这些装置用于支持和改变梗塞区域内和跨越梗死区域的心肌组织。这些装置通过在与梗塞相邻的位置处将装置附接到心肌而在不同程度上提供跨梗死的张力。在心脏附着位点之间的梗死区域的支持提供组件提供对心肌壁的支持并跨越梗塞的支持。可选地，但是优选地，支撑提供部件包括时间延迟元件，其可以不同地允许将装置引入心肌表面并随时间改变支撑元件的支撑。

50. 发明申请

US20090281372A1 CARDIAC HARNESS ASSEMBLY FOR TREATING CONGESTIVE HEART FAILURE AND FOR DEFIBRILLATION AND/OR PACING/SENSING 审中-公开
标题翻译：心脏线束组件用于治疗顽固性心脏衰竭和用于癫痫发作和/或皮肤/感觉
公开(公告)号：US20090281372A1
公开(公告)日：2009-11-12
申请号：US12115704
申请日：2008-05-06
申请人： Matthew G. Fishler
发明人： Matthew G. Fishler
IPC分类号： A61F2/00 , B29C45/14
CPC分类号： A61F2/2481 , A61N1/0587 , B29C45/14549 , B29C45/14778 , B29K2083/00 , B29K2705/00
摘要： A cardiac harness assembly for treating congestive heart failure and for use in defibrillation and/or pacing/sensing is provided. The cardiac harness includes a number of longitudinal ribs spaced apart by connectors, the longitudinal ribs extending from the base to the apex of the heart. The longitudinal ribs have a high degree of longitudinal flexibility so that when the cardiac harness is mounted on the heart, the longitudinal ribs flex along the longitudinal axis of the ribs as the heart expands and contracts circumferentially. The cardiac harness provides a uniform and continuous compressive force on the heart throughout the cardiac cycle.
摘要翻译：提供用于治疗充血性心力衰竭并用于除颤和/或起搏/感测的心脏线束组件。心脏线束包括由连接器间隔开的多个纵向肋，纵向肋从基部延伸到心脏的顶点。纵向肋具有高度的纵向柔性，使得当心脏线束安装在心脏上时，随着心脏膨胀和周向收缩，纵向肋沿着肋的纵向轴线弯曲。心脏线束在心脏周期内在心脏上提供均匀且持续的压缩力。

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