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41. 发明授权

US07022672B2 Formulation, solubilization, purification, and refolding of tissue factor pathway inhibitor 失效
公开(公告)号：US07022672B2
公开(公告)日：2006-04-04
申请号：US09996588
申请日：2001-11-30
申请人： Glenn J. Dorin , Bo H. Arve , Gregory L. Pattison , Robert F. Halenbeck , Kirk Johnson , Bao-Lu Chen , Rejsharan K. Bana , Maninder S. Hoba , Hassan Madani , Michael Tsang , Mark E. Gustafson , Gary S. Bild , Gary V. Johnson
发明人： Glenn J. Dorin , Bo H. Arve , Gregory L. Pattison , Robert F. Halenbeck , Kirk Johnson , Bao-Lu Chen , Rejsharan K. Bana , Maninder S. Hoba , Hassan Madani , Michael Tsang , Mark E. Gustafson , Gary S. Bild , Gary V. Johnson
IPC分类号： A61K38/00 , C07K14/00
CPC分类号： C07K14/475 , A23L7/111 , A23L7/165 , A23L9/10 , A23L9/22 , A23L19/09 , A23L19/18 , A23L21/15 , A23L29/212 , A23L29/219 , A23P20/12 , A61K9/0019 , A61K9/08 , A61K38/57 , A61K47/02 , A61K47/12 , A61K47/183 , A61K47/36 , C07K1/1136 , C07K14/8114 , Y10S514/97 , Y10S514/973
摘要： A method of modifying protein solubility employs polyionic polymers. These facilitate the solubilization, formulation, purification and refolding of proteins especially incorrectly folded proteins and aggregated proteins. Compositions are described that are suitable for formulating TFPI. The compositions allow preparation of pharmaceutically acceptable compositions of TFPI at concentrations above 0.2 mg/mL and above 10 mg/mL.

42. 发明申请

US20050170058A1 Jelly food containing soybean 7s-protein 审中-公开
标题翻译：含有大豆7s蛋白的果冻食品
公开(公告)号：US20050170058A1
公开(公告)日：2005-08-04
申请号：US10509594
申请日：2003-04-03
申请人： Toshimitsu Baba , Mitsuka Kohno , Motohiko Hirotsuka
发明人： Toshimitsu Baba , Mitsuka Kohno , Motohiko Hirotsuka
IPC分类号： A23J3/16 , A23L21/12 , A23L21/15 , A23L1/05
CPC分类号： A23J3/16 , A23L21/12 , A23L21/15 , A23V2002/00 , A23V2250/5488 , A23V2250/5024 , A23V2250/032 , A23V2250/5072
摘要： A jelly food containing soybean protein that even when a soybean protein is contained, realizes high storage stability, exhibits low probability of deposition at a weak acid zone and ensures excellent flavor. In particular, jelly food wherein use is made of low phytic acid soybean 7S-protein. More particularly, a jelly food containing soybean 7S-protein wherein the phytic acid content is 0.2% or less, preferably 0.1% or less, per protein.
摘要翻译：含有大豆蛋白质的大豆蛋白质的果冻食品即使含有大豆蛋白也能实现高储存稳定性，在弱酸性区域的沉积概率低，并且确保优异的风味。特别是使用低植酸大豆7S蛋白质的果冻食品。更具体地，是含有大豆7S蛋白质的果冻食品，其中植酸含量为每个蛋白质0.2％以下，优选0.1％以下。

43. 发明申请

US20050032710A1 Alternative agent with vitamin D-like activity and an improving agent for intestinal function 审中-公开
标题翻译：具有维生素D样活性的替代药物和肠功能改善剂
公开(公告)号：US20050032710A1
公开(公告)日：2005-02-10
申请号：US10845362
申请日：2004-05-14
申请人： Hidetake Fujinaka , Junji Nakamura , Daiki Murase , Hatsumi Souno , Hisataka Kobayashi
发明人： Hidetake Fujinaka , Junji Nakamura , Daiki Murase , Hatsumi Souno , Hisataka Kobayashi
IPC分类号： A21D2/16 , A21D2/18 , A23C9/152 , A23F3/14 , A23G3/00 , A23G3/34 , A23G3/36 , A23G3/42 , A23G9/32 , A23G9/34 , A23L1/068 , A23L1/09 , A23L1/302 , A23L2/39 , A23L2/52 , A61K31/7024
CPC分类号： A23F3/14 , A21D2/16 , A21D2/18 , A23C9/1522 , A23G3/346 , A23G3/36 , A23G3/42 , A23G9/32 , A23G9/34 , A23G2200/00 , A23G2200/04 , A23L2/39 , A23L2/52 , A23L5/00 , A23L7/00 , A23L21/00 , A23L21/15 , A23L29/30 , A23L33/125 , A23L33/15 , A23V2002/00 , A61K31/7024 , A23V2250/7042 , A23V2250/7044 , A23V2250/7052 , A23V2250/708 , A23V2250/712 , A23V2250/628 , A23V2250/5036 , A23V2250/507 , A23V2250/032 , A23V2200/32 , A23V2250/54246 , A23V2250/0632 , A23V2250/70 , A23V2250/156 , A23V2250/5108 , A23V2250/5118
摘要： The present invention relates to an alternative agent with vitamin D-like activity or an improving agent for age-related depression of intestinal function, comprising a sugar-phosphate ester or a salt thereof, as an active ingredient.
摘要翻译：本发明涉及具有维生素D样活性的替代药剂或用于年龄相关的肠功能障碍的改善剂，其包含糖磷酸酯或其盐作为活性成分。

44. 发明申请

US20050003047A1 Intestinal mineral absorption capacity improver 审中-公开
标题翻译：肠道矿物吸收能力改良剂
公开(公告)号：US20050003047A1
公开(公告)日：2005-01-06
申请号：US10845120
申请日：2004-05-14
申请人： Hidetake Fujinaka , Junji Nakamura , Daiki Murase , Hatsumi Souno , Hisataka Kobayashi
发明人： Hidetake Fujinaka , Junji Nakamura , Daiki Murase , Hatsumi Souno , Hisataka Kobayashi
IPC分类号： A21D2/16 , A21D2/18 , A23C9/152 , A23F3/14 , A23G3/00 , A23G3/34 , A23G3/36 , A23G3/42 , A23G9/32 , A23G9/34 , A23L1/068 , A23L1/09 , A23L1/302 , A23L2/39 , A23L2/52 , A61K31/7024 , A23K1/175
CPC分类号： A23F3/14 , A21D2/16 , A21D2/18 , A23C9/1522 , A23G3/346 , A23G3/36 , A23G3/42 , A23G9/32 , A23G9/34 , A23G2200/00 , A23G2200/04 , A23L2/39 , A23L2/52 , A23L5/00 , A23L7/00 , A23L21/00 , A23L21/15 , A23L29/30 , A23L33/125 , A23L33/15 , A23V2002/00 , A61K31/7024 , A23V2250/7042 , A23V2250/7044 , A23V2250/7052 , A23V2250/708 , A23V2250/712 , A23V2250/628 , A23V2250/5036 , A23V2250/507 , A23V2250/032 , A23V2200/32 , A23V2250/54246 , A23V2250/0632 , A23V2250/70 , A23V2250/156 , A23V2250/5108 , A23V2250/5118
摘要： The present invention relates to an intestinal mineral absorption capacity improver containing glucose 1-phosphate sodium salt as an effective ingredient.
摘要翻译：本发明涉及含有葡萄糖-1-磷酸钠盐作为有效成分的肠内矿物质吸收能力改进剂。

45. 发明申请

US20040208977A1 Pearl starch ball product with filling of natural fruits or vegetables 审中-公开
标题翻译：珍珠淀粉球产品，填充天然水果或蔬菜
公开(公告)号：US20040208977A1
公开(公告)日：2004-10-21
申请号：US09887044
申请日：2001-06-25
发明人： Mei-Li Chuang Chien , Min-Chih Chuang , Min-Jan Chuang
IPC分类号： A23K001/00
CPC分类号： A23L19/05 , A23L7/1963 , A23L11/01 , A23L11/03 , A23L21/15 , A23L29/284 , A23P20/12
摘要： A pearl starch ball product with filling of natural fruits or vegetables, the said pearl starch ball product can be divided into at least an inner layer and an outer layer, the inner layer is the filling ingredient primarily made of fruits, five grains, vegetables or healthy food ingredients from Chinese herb medicines, the outer layer is a starch layer covering on the external periphery of the filling ingredient, wherein the filling ingredient can be further divided into more than two layers of different ingredient layers, from the inside to the outside respectively, the first layer is a layer of fruits or vegetables, the second layer is a sugar coating, etc.; the implement of the present invention enables the pearl starch ball not only possess the original chewy texture, but also possess the luscious flavor of the grains of natural fruits or vegetables.
摘要翻译：具有天然水果或蔬菜馅料的珍珠淀粉球产品，所述珍珠淀粉球产品可分为至少内层和外层，内层为主要由水果，五粒，蔬菜或中草药的健康食品成分，外层是覆盖在填充成分外周的淀粉层，其中填充成分可以从内向外分为两层以上不同的成分层第一层是一层水果或蔬菜，第二层是糖衣等; 本发明的工具使得珍珠淀粉球不仅具有原始的耐嚼质地，而且具有天然水果或蔬菜颗粒的甜味。

46. 发明申请

US20040052880A1 Oral preparations having itching-relievign or antipruritic activity 审中-公开
标题翻译：口服制剂具有瘙痒 - 相反或反痒活性
公开(公告)号：US20040052880A1
公开(公告)日：2004-03-18
申请号：US10433788
申请日：2003-06-06
发明人： Yoshinori Kobayashi , Yumiko Nakano , Kiyoko Inayama , Akiko Sakai , Toshikazu Kamiya
IPC分类号： A61K035/78
CPC分类号： A61K9/0095 , A21D2/16 , A21D2/36 , A23F3/163 , A23F3/34 , A23G3/346 , A23G3/48 , A23G4/068 , A23G9/42 , A23G2200/14 , A23K10/30 , A23K20/10 , A23L2/38 , A23L21/12 , A23L21/15 , A23L27/11 , A23L33/105 , A23V2002/00 , A61K9/0058 , A61K9/2018 , A61K9/4858 , A61K36/28 , A23V2250/21 , A23V2250/708 , A23V2250/7042 , A23V2250/7044 , A23V2250/7052 , A23V2250/032
摘要： The present invention relates to oral preparations, foods, drinks, feeds, food additives or feed additives having an itching-relieving or antipruritic activity which contain, as an active ingredient, plant body of a plant that belongs to the genus Matricaria or Anthemis or an extract of the plant body.
摘要翻译：本发明涉及具有瘙痒缓解或止痒活性的口服制剂，食品，饮料，饲料，食品添加剂或饲料添加剂，其含有属于母菊属或蚁草属植物的植物体作为活性成分，或植物体提取物。

47. 发明授权

US06620445B1 Alkali metal bisulfates as acidulants in food 有权
标题翻译：碱金属硫酸氢盐作为食品中的酸化剂
公开(公告)号：US06620445B1
公开(公告)日：2003-09-16
申请号：US09635821
申请日：2000-08-09
申请人： Carl Joseph Knueven
发明人： Carl Joseph Knueven
IPC分类号： A21D400
CPC分类号： A23L2/68 , A21D2/02 , A21D4/00 , A23G1/305 , A23G1/56 , A23G3/362 , A23G2210/00 , A23L7/117 , A23L21/10 , A23L21/15 , A23L27/60 , A23L27/82 , A23L29/015 , A23L29/284
摘要： A method for providing an acidulant effect in a food. A food is prepared including alkali metal bisulfate in an amount effective to act as an acidulant. Moisture is added in an amount effective to dissolve the alkali metal bisulfate. In a preferred embodiment, a leavened baked good is prepared including a baking carbonate, and alkali metal bisulfate in an amount effective to react with the baking carbonate to release carbon dioxide to leaven the baked good. A food composition includes alkali metal bisulfate in an amount effective to act as an acidulant in the food, and moisture in an amount effective to dissolve the alkali metal bisulfate.
摘要翻译：一种在食物中提供酸化效果的方法。制备的食品包括碱金属硫酸氢盐，其量有效地用作酸化剂。以有效溶解碱金属硫酸氢盐的量添加水分。在优选的实施方案中，制备发酵烘焙食品，其包括焙烧碳酸盐和碱金属硫酸氢盐，其量可以有效地与焙烧碳酸盐反应以释放二氧化碳以使焙烤物发酵。食品组合物包含碱金属硫酸氢盐，其量可以有效地作为食品中的酸化剂，和水分以有效溶解碱金属硫酸氢盐的量。

48. 发明申请

US20020132031A1 Edible food produced such as sports beverages, health drinks, fruit bars, jams and jellies 有权
标题翻译：生产的食用食品如运动饮料，保健饮料，水果酒吧，果酱和果冻
公开(公告)号：US20020132031A1
公开(公告)日：2002-09-19
申请号：US10050398
申请日：2002-01-15
发明人： Israel N. Rabinowitz
IPC分类号： A23L001/20 , A23L001/28
CPC分类号： A23L2/385 , A23L2/02 , A23L21/15 , A23L25/30
摘要： Commuting dry almond hulls into fine particles, infusing the particles with water, extracting soluble compounds from them in a counter-current aqueous process. Separating the fibers to provide an aqueous solution, and ultrafiltering the remaining aqueous solution to provide ingredients for products such as sports beverages, health drinks, fruit bars, jams, jellies, and fibers. If desired, the aqueous solution from counter-current extraction can be treated with a yeast to increase the inositol content of the aqueous solution.
摘要翻译：将干燥的杏仁皮包裹成细颗粒，用水注入颗粒，以逆流水溶液方式从中提取可溶性化合物。分离纤维以提供水溶液，并对剩余的水溶液进行超滤，以提供诸如运动饮料，保健饮料，水果酒吧，果酱，果冻和纤维之类的产品的成分。如果需要，来自逆流萃取的水溶液可以用酵母处理以增加水溶液的肌醇含量。

49. 发明授权

US06451121B2 Thermally-inhibited non-pregelatinized granular starches and flours and process for their preparation 失效
标题翻译：耐热非预胶化粒状淀粉和面粉并进行制备
公开(公告)号：US06451121B2
公开(公告)日：2002-09-17
申请号：US09798520
申请日：2001-03-02
申请人： Chung-Wai Chiu , Eleanor Schiermeyer , David J. Thomas , Manish B. Shah , Douglas J. Hanchett , Roger Jeffcoat
发明人： Chung-Wai Chiu , Eleanor Schiermeyer , David J. Thomas , Manish B. Shah , Douglas J. Hanchett , Roger Jeffcoat
IPC分类号： C08B3000
CPC分类号： A23G9/34 , A21D2/186 , A21D6/00 , A21D6/003 , A23C9/137 , A23C19/0765 , A23G3/346 , A23G9/52 , A23G2200/06 , A23L7/111 , A23L7/165 , A23L7/198 , A23L9/10 , A23L19/09 , A23L19/18 , A23L21/15 , A23L21/18 , A23L23/00 , A23L27/60 , A23L27/63 , A23L29/212 , A23L29/219 , A23L29/225 , A23P20/12 , C08B30/12 , C08B30/14
摘要： Thermally-inhibited starches and flours which are functionally equivalent to chemically-crosslinked starches are prepared by a process which comprises the steps of dehydrating a granular starch or flour to anhydrous or substantially anhydrous (
摘要翻译：在功能上等同于化学交联淀粉的热抑制淀粉和面粉通过包括以下步骤的方法制备，所述方法包括以下步骤：将颗粒状淀粉或面粉脱水至无水或基本无水（<1％水分）并热处理脱水淀粉或面粉一段时间并且足以抑制淀粉的温度（例如，120-180℃长达20小时）。优选地，在脱水之前将淀粉的pH调节至中性或更高（例如，pH 8-9.5）。脱水可以是与热处理同时进行的热脱水或通过用溶剂（例如乙醇）萃取或通过冷冻干燥进行的非热脱水。

50. 发明授权

US06444252B1 Methods of preparation of gel products fortified with calcium 有权
标题翻译：用钙强化的凝胶产品的制备方法
公开(公告)号：US06444252B1
公开(公告)日：2002-09-03
申请号：US09596512
申请日：2000-06-19
申请人： Daniel L. Gordon , Souyma Roy , Ann L. Ryan , Kelly S. Schwenn
发明人： Daniel L. Gordon , Souyma Roy , Ann L. Ryan , Kelly S. Schwenn
IPC分类号： A23L105
CPC分类号： A23G3/36 , A23G3/362 , A23G3/40 , A23G3/48 , A23G3/54 , A23L21/12 , A23L21/15 , A23L29/212 , A23L29/231 , A23V2002/00 , A23V2250/5024 , A23V2250/5054 , A23V2250/5118 , A23V2250/50722 , A23V2250/032 , A23V2250/1578 , A23V2250/5432
摘要： Disclosed are improved, intermediate moisture sweetened gelled food compositions fortified with calcium supplied by calcium phosphate that is dispersed in an oil and/or fat. The gelled compositions comprise: A) about 55 to 85% by weight nutritive carbohydrate sweeteners; B) sufficient amounts of a gelling agent(s) to provide a gel strength of about 2-8 kg/cm2; C) about 50 to 1500 mg/oz total calcium; and D) about 9 to 20% moisture, and E) about to 0.1% to 5% of an edible fatty triglyceride. Also disclosed are methods for the preparation of such fruit products involving forming a concentrated slurry of calcium phosphate having a particle size such that at least 90% are less than 150 &mgr;m dispersed in at least a portion of the oil and/or fat, forming a gellable blend and admixing the gellable composition with the slurry to form a gellable calcium fortified composition and forming into desired shaped and sized pieces.
摘要翻译：公开了改进的中和水分甜化胶凝食品组合物，其被分散在油和/或脂肪中的由磷酸钙提供的钙强化。凝胶组合物包含：A）约55至85重量％的营养碳水化合物甜味剂; B）足够量的胶凝剂以提供约2-8kg / cm2的凝胶强度; C）约50至1500mg /盎司总钙; 和D）约9至20％的水分，以及E）约0.1％至5％的食用脂肪甘油三酯。还公开了用于制备这种水果产品的方法，包括形成磷酸钙的浓缩浆料，其具有使得至少90％小于150μm的颗粒分散在至少一部分油和/或脂肪中，形成可胶凝的混合物并将可凝胶组合物与浆料混合以形成可胶凝的钙强化组合物并形成所需的形状和尺寸的碎片。

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