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41. 发明授权

US08637516B2 Compounds and compositions as TRK inhibitors 失效
标题翻译：化合物和组合物作为TRK抑制剂
公开(公告)号：US08637516B2
公开(公告)日：2014-01-28
申请号：US13227957
申请日：2011-09-08
申请人： Yi Fan , Jon Loren , Valentina Molteni , Pamela A. Albaugh , Gregory Chopiuk , Jeffrey M. Smith , Brenton T. Flatt
发明人： Yi Fan , Jon Loren , Valentina Molteni , Pamela A. Albaugh , Gregory Chopiuk , Jeffrey M. Smith , Brenton T. Flatt
IPC分类号： A01N43/58 , A61K31/50 , C07D487/00
CPC分类号： C07D471/04 , C07D487/04
摘要： The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TRK kinase activity.
摘要翻译：本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的TRK激酶活性相关的疾病或病症的方法。

42. 发明申请

US20140001098A1 Method and Device for Enclosed Recycling of Oil-Water-Sludge in Oil Shale Dry Distillation System 审中-公开
标题翻译：油页岩干馏系统油水污泥封闭回收方法与装置
公开(公告)号：US20140001098A1
公开(公告)日：2014-01-02
申请号：US13884156
申请日：2011-12-13
申请人： Mingfu Bao , Hualin Wang , Dasong Xing , Jiangang Wang , Da Zhao , Xin Cui , Rongpu Zhang , Yuan Huang , Ling Shen , Qiang Yang , Yi Fan
发明人： Mingfu Bao , Hualin Wang , Dasong Xing , Jiangang Wang , Da Zhao , Xin Cui , Rongpu Zhang , Yuan Huang , Ling Shen , Qiang Yang , Yi Fan
IPC分类号： C10G33/04
CPC分类号： C10G33/04 , C02F11/12 , C10B53/06 , C10G1/00 , C10G1/002 , C10G1/02 , C10G5/04 , C10G33/02 , C10G2300/4081 , C10K1/02 , C10K1/04
摘要： The present invention relates to a method and a device for enclosed recycling of oil-water-sludge in an oil shale dry distillation system. According to the method, the technology is advanced, equipment investment costs are low, the occupied area is small, the failure rate is low, a highly pure shale oil product and a highly concentrated oil sludge product can be obtained efficiently, and the waste water generated in the purification and concentration processes can be recycled, thereby achieving full enclosure of the device system, greatly reducing the energy consumption, and improving the oil shale dry distillation process in the prior art.
摘要翻译：本发明涉及油页岩干馏系统中油 - 水污泥的封闭回收方法和装置。按照该方法，技术先进，设备投资成本低，占地面积小，故障率低，可以高效地获得高纯度页岩油产品和高浓缩油泥产品，废水在净化和浓缩过程中产生的可以再循环，从而实现装置系统的完全封闭，大大降低了能量消耗，并改进了现有技术中的油页岩干馏过程。

43. 发明授权

US08507488B2 Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors 有权
标题翻译：熔融的含氮杂环及其组合物作为激酶抑制剂
公开(公告)号：US08507488B2
公开(公告)日：2013-08-13
申请号：US12992027
申请日：2009-05-07
申请人： Pamela A. Albaugh , Ha-Soon Choi , Gregory Chopiuk , Yi Fan , Paul Vincent Rucker , Zhicheng Wang
发明人： Pamela A. Albaugh , Ha-Soon Choi , Gregory Chopiuk , Yi Fan , Paul Vincent Rucker , Zhicheng Wang
IPC分类号： A01N43/58 , A61K31/495 , C07D487/00
CPC分类号： C07D471/04 , C07D487/04
摘要： The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Ros, KDR, FMS, C-FMS, FLT3, c-Kit, JAK2, JAK3, Aurora, PDGFR, Lck, TrkA, TrkB, TrkC, IGF-IR, ALK4, ALK5 and ALK or combinations thereof.
摘要翻译：本发明提供化合物，包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调激酶活性相关的疾病或病症的方法，特别是Ros，KDR，FMS，C-FMS，FLT3，c-Kit，JAK2， JAK3，Aurora，PDGFR，Lck，TrkA，TrkB，TrkC，IGF-1R，ALK4，ALK5和ALK或其组合。

44. 发明申请

US20120010408A1 Method for Preparing Acyclovir 2/3 Hydrate 有权
标题翻译：阿昔洛韦2/3水合物的制备方法
公开(公告)号：US20120010408A1
公开(公告)日：2012-01-12
申请号：US13259466
申请日：2010-03-17
申请人： Tong Pu , Yi Fan , Tian Chen , Ming Lei , Naixing Wang , Zhen Yang
发明人： Tong Pu , Yi Fan , Tian Chen , Ming Lei , Naixing Wang , Zhen Yang
IPC分类号： C07D473/18
CPC分类号： A61K31/522 , C07D473/18
摘要： Preparation of acyclovir 2/3 hydrate comprises mixing acyclovir with water at weight ratio of 1:5˜50, dissolving at 50˜100° C., filtering, cooling filtrate at 0˜30° C. to precipitate crystal, collecting the crystal by filtration, and drying the crystal at 0˜150° C. for 0.5˜24 hours to obtain acyclovir 2/3 hydrate. The preparation process is simple and suitable for industrial production. The prepared product has good and stable crystal form.
摘要翻译：阿昔洛韦2/3水合物的制备包括将阿昔洛韦与水的重量比为1:5〜50混合，在50〜100℃下溶解，过滤，在0〜30℃下冷却滤液，使晶体析出，收集晶体，过滤，并在0〜150℃干燥晶体0.5〜24小时，得到无环鸟苷2/3水合物。制备工艺简单，适合工业生产。制备的产品具有良好稳定的晶体形式。

45. 发明授权

US07920490B2 Systems and methods for wireless transmission and reception of data including frequency and channel code selection 有权
标题翻译：无线传输和接收数据的系统和方法，包括频率和频道选择
公开(公告)号：US07920490B2
公开(公告)日：2011-04-05
申请号：US11809267
申请日：2007-05-30
申请人： Christopher Deng , Yi Fan , Igor Elgorriaga
发明人： Christopher Deng , Yi Fan , Igor Elgorriaga
IPC分类号： H04B7/005
CPC分类号： H04B7/12 , H04L1/0025 , H04L1/1607 , H04L1/1887
摘要： Systems and methods are disclosed for wireless transmission and reception of data including processing and buffering features. According to one or more exemplary aspects, there is provided a wireless audio receiver for receiving a plurality of packets of encoded audio data. Moreover, the receiver includes at least one receiving component that receives the plurality of packets to generate a plurality of decoded signals, a decoding component that decodes the first packet of encoded data transmitted to produce decoded data, and a selecting component that identifies the mechanisms for receiving additional encoded data. Other exemplary embodiments may include one or more receiving components that processing data regarding antenna, frequencies and channels selected for transmission, as well as an audio component that receives the decoded signals and produces decoded audio signals.
摘要翻译：公开了用于无线传输和接收包括处理和缓冲特征的数据的系统和方法。根据一个或多个示例性方面，提供了一种用于接收多个编码音频数据分组的无线音频接收器。此外，接收机包括接收多个分组以生成多个解码信号的至少一个接收组件，解码发送的第一编码数据分组以产生解码数据的解码部件，以及识别用于接收附加的编码数据。其它示例性实施例可以包括处理关于选择用于传输的天线，频率和信道的数据的一个或多个接收组件，以及接收解码信号并产生解码音频信号的音频组件。

46. 发明申请

US20090190718A1 X-RAY IMAGING APPARATUS AND PORTABLE DETECTOR PANEL 有权
标题翻译： X射线成像设备和便携式探测器面板
公开(公告)号：US20090190718A1
公开(公告)日：2009-07-30
申请号：US12358856
申请日：2009-01-23
申请人： Yi Fan
发明人： Yi Fan
IPC分类号： H05G1/10
CPC分类号： A61B6/4283 , A61B6/4405
摘要： An X-ray imaging apparatus includes: a mobile system console with an X-ray irradiator and a control circuit; and a portable detector panel with an X-ray detector, an interface electronic circuit, and a power supply battery. The system console includes an accommodating section for accommodating the detector panel at the time of nonuse, and the detector panel includes feeding control device for unexecuting and executing feeding to the electronic circuit from the battery according to the accommodation and non-accommodation in the accommodating section, respectively.
摘要翻译： X射线成像装置包括：具有X射线照射器和控制电路的移动系统控制台; 以及具有X射线检测器，接口电子电路和电源电池的便携式检测器面板。所述系统控制台包括用于在不使用时容纳所述检测器面板的容纳部分，并且所述检测器面板包括供给控制装置，用于根据所述容纳部分中的容纳和不接合从所述电池执行和执行对所述电子电路的馈送，分别。

47. 发明申请

US20080298242A1 SYSTEMS AND METHODS FOR TRANSMISSION AND RECEPTION OF DATA INCLUDING PROCESSING AND BUFFERING FEATURES 审中-公开
标题翻译：用于传输和接收数据的系统和方法，包括处理和缓冲特性
公开(公告)号：US20080298242A1
公开(公告)日：2008-12-04
申请号：US12060825
申请日：2008-04-01
申请人： Yi Fan , Christopher Deng , Igor Elgorriaga , Mau-Chung Frank Chang
发明人： Yi Fan , Christopher Deng , Igor Elgorriaga , Mau-Chung Frank Chang
IPC分类号： H04L7/00
CPC分类号： H04J3/0632 , G10L19/167 , H04J3/12 , H04L1/1835 , H04L1/1867 , H04L47/10 , H04L47/14 , H04L47/22 , H04L47/30
摘要： The present invention relates to a wireless data system which has a transmitter including a transmission buffer. The transmitter is configured to transmit a plurality of packets of encoded data, wherein a level of the transmission buffer is encoded in one of the packets of encoded data. The system further has a wireless receiver for receiving the plurality of packets. The receiver has at least one receiving component that receives the plurality of packets to generate a plurality of decoded signals, wherein the at least one receiving component is configured to receive one of the packets of encoded data from the transmitter to determine the level of transmission buffer. The receiving component is further configured to store the plurality of packets received in a receive buffer, to determine the level of the receive buffer, and to calculate an aggregate buffer level from the transmission buffer and the receive buffer. The receiver controls a packet output rate from the receive buffer to maintain the aggregate buffer level at a desired level.
摘要翻译：本发明涉及一种具有发送器的无线数据系统，发送器包括发送缓冲器。发送器被配置为发送多个编码数据分组，其中传输缓冲器的级别被编码在编码数据的分组之一中。该系统还具有用于接收多个分组的无线接收机。所述接收机具有接收所述多个分组以生成多个解码信号的至少一个接收组件，其中所述至少一个接收组件被配置为从所述发射机接收编码数据分组中的一个以确定所述发射缓冲器的电平。接收组件还被配置为存储在接收缓冲器中接收的多个分组，以确定接收缓冲器的电平，并且从发送缓冲器和接收缓冲器计算聚合缓冲器电平。接收器控制来自接收缓冲器的分组输出速率，以将聚合缓冲器级别保持在期望的水平。

48. 发明授权

US07417065B2 Immunosuppressant compounds and compositions 有权
公开(公告)号：US07417065B2
公开(公告)日：2008-08-26
申请号：US10849458
申请日：2004-05-19
申请人： Yuan Mi , Shifeng Pan , Nathanael Schiander Gray , Wenqi Gao , Yi Fan , Tao Jiang
发明人： Yuan Mi , Shifeng Pan , Nathanael Schiander Gray , Wenqi Gao , Yi Fan , Tao Jiang
IPC分类号： A61K31/381 , C07D333/62
CPC分类号： C07D333/58 , C07D261/20 , C07D409/06 , C07D471/04 , C07D473/00 , C07D513/04
摘要： The present invention relates to immunosuppressant, process for their production, their uses and pharmaceutical compositions containing them. The invention provides a novel class of compounds useful in the treatment or prevention of diseases or disorders mediated by lymphocyte interactions, particularly diseases associated with EDG receptor mediated signal transduction.

49. 发明申请

US20080076801A1 Indolylalkylpyridin-2-amines for the inhibition of beta-secretase 审中-公开
标题翻译：用于抑制β-分泌酶的吲哚基烷基吡啶-2-胺
公开(公告)号：US20080076801A1
公开(公告)日：2008-03-27
申请号：US11903073
申请日：2007-09-20
申请人： Yinfa Yan , Ping Zhou , Yi Fan , Albert Robichaud , Michael Malamas
发明人： Yinfa Yan , Ping Zhou , Yi Fan , Albert Robichaud , Michael Malamas
IPC分类号： A61K31/4375 , A61P25/28 , C07D213/02
CPC分类号： C07D401/06
摘要： The present invention provides an indolylalkylpyridin-2-amine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
摘要翻译：本发明提供式I的吲哚基烷基吡啶-2-胺化合物本发明还提供了用于抑制β-分泌酶（BACE）和治疗β-淀粉样沉积物和神经原纤维缠结的方法。

50. 发明申请

US20070038867A1 System for biometric signal processing with hardware and software acceleration 审中-公开
标题翻译：用于硬件和软件加速的生物信号处理系统
公开(公告)号：US20070038867A1
公开(公告)日：2007-02-15
申请号：US10554763
申请日：2004-06-02
申请人： Ingrid Verbauwhede , Patrick Schaumont , David Hwang , Bo-Cheng Lai , Shenglin Yang , Kazuo Sakiyama , Yi Fan , Alireza Hodjat
发明人： Ingrid Verbauwhede , Patrick Schaumont , David Hwang , Bo-Cheng Lai , Shenglin Yang , Kazuo Sakiyama , Yi Fan , Alireza Hodjat
IPC分类号： H04K1/00
CPC分类号： G06Q20/12 , G06F21/32 , G06Q20/4014 , G07C9/00087 , H04L9/0637 , H04L9/085 , H04L9/16 , H04L9/3231 , H04L9/3242 , H04L2209/12 , H04L2209/56 , H04L2209/805
摘要： A secure embedded system that uses cryptographic and biometric signal processing acceleration is described. In one embodiment, the secure embedded system is configured as a wireless pay-point protocol for brick-and-mortar and e-commerce applications in which biometric information is localized and does not require transmission of biometric data for authentication. In one embodiment, a key-generation function uses a dynamic key generator and static biometric components. In one embodiment, an embedded system design methodology provides hardware and software acceleration transparency.
摘要翻译：描述了使用加密和生物特征信号处理加速的安全嵌入式系统。在一个实施例中，安全嵌入式系统被配置为用于实体和电子商务应用的无线支付点协议，其中生物特征信息被定位并且不需要用于认证的生物特征数据的传输。在一个实施例中，密钥生成功能使用动态密钥生成器和静态生物特征组件。在一个实施例中，嵌入式系统设计方法提供硬件和软件加速透明度。

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