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41. 发明授权

US08338593B2 Modulators of toll-like receptor 7 有权
标题翻译： toll样受体7的调节剂
公开(公告)号：US08338593B2
公开(公告)日：2012-12-25
申请号：US12303214
申请日：2007-07-06
申请人： Lee S. Chong , Manoj C. Desai , Brian Gallagher , Michael Graupe , Randall L. Halcomb , Hong Yang , Jennifer R. Zhang
发明人： Lee S. Chong , Manoj C. Desai , Brian Gallagher , Michael Graupe , Randall L. Halcomb , Hong Yang , Jennifer R. Zhang
IPC分类号： C07F9/6561 , C07D473/16 , A61K31/675 , A61P31/20 , C07D473/40
CPC分类号： C07F9/65616
摘要： The present application provides for a compound of Formula (I) or (II): or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods that include the administration of such compounds with at least one additional active agent.
摘要翻译：本申请提供式（I）或（II）的化合物或其药学上可接受的盐，溶剂合物和/或酯，含有这些化合物的组合物，包括施用这些化合物的治疗方法和治疗方法，包括给予这些化合物与至少一种另外的活性剂。

42. 发明授权

US08318791B2 Substituted imidazole derivatives 有权
标题翻译：取代的咪唑衍生物
公开(公告)号：US08318791B2
公开(公告)日：2012-11-27
申请号：US12455798
申请日：2009-06-05
申请人： Weibo Wang , Paul A. Barsanti , Yia Xia , Rustum Boyce , Sabina Pecchi , Nathan Brammeier , Megan C. Phillips , Kris Mendenhall , Kelly Wayman , Liana Marie Lagniton , Ryan Constantine , Hong Yang , Elizabeth Mieuli , Savithri Ramurthy , Elisa Jazan , Anu Sharma , Rama Jain , Sharadha Subramanian , Paul A. Renhowe , Kenneth W. Bair , David Duhl , Annette Walter , Tinya Abrams , Kay Huh , Eric Martin , Mark Knapp , Vincent P. Le
发明人： Weibo Wang , Paul A. Barsanti , Yia Xia , Rustum Boyce , Sabina Pecchi , Nathan Brammeier , Megan C. Phillips , Kris Mendenhall , Kelly Wayman , Liana Marie Lagniton , Ryan Constantine , Hong Yang , Elizabeth Mieuli , Savithri Ramurthy , Elisa Jazan , Anu Sharma , Rama Jain , Sharadha Subramanian , Paul A. Renhowe , Kenneth W. Bair , David Duhl , Annette Walter , Tinya Abrams , Kay Huh , Eric Martin , Mark Knapp , Vincent P. Le
IPC分类号： A61K39/395 , A61K31/4178 , A61K31/427 , A61K31/5386 , A61K31/4174
CPC分类号： C07D233/54 , C07D233/24 , C07D233/64 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/06 , C07D405/12 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D498/10
摘要： The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula:
摘要翻译：本发明涉及新的取代的咪唑化合物及其药学上可接受的盐，酯或前药，新化合物的组合物和药学上可接受的载体，以及新化合物的用途。本发明的化合物具有以下通式：

43. 发明授权

US08262537B2 Method for transitioning control in a multi-mode hybrid transmission 有权
标题翻译：用于在多模混合传输中转换控制的方法
公开(公告)号：US08262537B2
公开(公告)日：2012-09-11
申请号：US12501603
申请日：2009-07-13
申请人： Hong Yang , Shawn H Swales , Joel M. MaGuire
发明人： Hong Yang , Shawn H Swales , Joel M. MaGuire
IPC分类号： B60W10/02
CPC分类号： B60K6/36 , B60K6/365 , B60K6/445 , B60W10/02 , B60W10/08 , B60W20/00 , F16H2037/0866 , F16H2037/101 , F16H2037/102 , F16H2037/108 , F16H2061/6603 , Y02T10/6239 , Y10T477/26
摘要： A multi-mode hybrid transmission including a selectable one-way clutch and first and second torque machines transitions to operating in a target continuously variable mode including applying a selectable one-way clutch and controlling input torque and motor torques of the first and second torque machines using a second kinematic relationship. A multi-step process is executed to transition the first clutch to a deactivated state, transition the second selectable one-way clutch to the applied state, and transition to using the second kinematic relationship to achieve a preferred output torque.
摘要翻译：一种包括可选择单向离合器和第一和第二扭矩机的多模混合变速器转变为以目标连续可变模式操作，包括施加可选择的单向离合器并控制第一和第二扭矩机的输入扭矩和电动机转矩使用第二运动关系。执行多步处理以将第一离合器转换到停用状态，将第二可选择单向离合器转换到施加状态，并且转换到使用第二运动学关系以实现优选的输出转矩。

44. 发明授权

US07820646B2 Cyclized derivatives as Eg-5 inhibitors 失效
标题翻译：环化衍生物作为Eg-5抑制剂
公开(公告)号：US07820646B2
公开(公告)日：2010-10-26
申请号：US11969164
申请日：2008-01-03
申请人： Rustum Boyce , Eric Martin , Weibo Wang , Hong Yang , Paul A. Barsanti
发明人： Rustum Boyce , Eric Martin , Weibo Wang , Hong Yang , Paul A. Barsanti
IPC分类号： C07D403/06 , C07D413/06 , A61K31/422 , A61P35/00
CPC分类号： C07D403/06 , C07D413/06
摘要： The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to uses of the compounds:
摘要翻译：本发明涉及具有下式（I）的新的取代咪唑化合物及其药学上可接受的盐，酯或前药与化合物与药学上可接受的载体的组合物，以及该化合物的用途：

45. 发明申请

US20090258016A1 Substituted imidazole derivatives 有权
标题翻译：取代的咪唑衍生物
公开(公告)号：US20090258016A1
公开(公告)日：2009-10-15
申请号：US12455798
申请日：2009-06-05
申请人： Weibo Wang , Paul A. Barsanti , Yia Xia , Rustum Boyce , Sabina Pecchi , Nathan Brammeier , Megan C. Phillips , Kris Mendenhall , Kelly Wayman , Liana Marie Lagniton , Ryan Constantine , Hong Yang , Elizabeth Mieuli , Savithri Ramurthy , Elisa Jazan , Anu Sharma , Rama Jain , Sharadha Subramanian , Paul A. Renhowe , Kenneth W. Bair , David Duhl , Annette Walter , Tinya Abrams , Kay Huh , Eric Martin , Mark Knapp , Vincent P. Le
发明人： Weibo Wang , Paul A. Barsanti , Yia Xia , Rustum Boyce , Sabina Pecchi , Nathan Brammeier , Megan C. Phillips , Kris Mendenhall , Kelly Wayman , Liana Marie Lagniton , Ryan Constantine , Hong Yang , Elizabeth Mieuli , Savithri Ramurthy , Elisa Jazan , Anu Sharma , Rama Jain , Sharadha Subramanian , Paul A. Renhowe , Kenneth W. Bair , David Duhl , Annette Walter , Tinya Abrams , Kay Huh , Eric Martin , Mark Knapp , Vincent P. Le
IPC分类号： A61K39/395 , A61K31/4178 , A61K31/427 , A61K31/5386 , A61K31/4174 , A61P35/00
CPC分类号： C07D233/54 , C07D233/24 , C07D233/64 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/06 , C07D405/12 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D498/10
摘要： The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula:
摘要翻译：本发明涉及新的取代的咪唑化合物及其药学上可接受的盐，酯或前药，新化合物的组合物和药学上可接受的载体，以及新化合物的用途。本发明的化合物具有以下通式：

46. 发明授权

US07540117B2 Vibration isolation system for building 失效
标题翻译：建筑隔振系统
公开(公告)号：US07540117B2
公开(公告)日：2009-06-02
申请号：US10522765
申请日：2003-08-04
申请人： Hong Yang
发明人： Hong Yang
IPC分类号： E04B1/98
CPC分类号： E04H9/021
摘要： A vibration isolation system for building, comprising a vibration isolation layer, the vibration isolation layer including: an upper layer structure consisted of upper beams and/or slabs and moveable bases, which is coupled to columns of the building; a lower layer structure consisted of lower beams and/or slabs and fixed bases; and vibration isolation devices and elastic member horizon-resetting devices which are mounted between the upper layer structure and the lower layer structure, in which the vibration isolation devices are mounted between the moveable bases and the fixed bases, respectively, and the elastic member horizon-resetting devices are mounted between the beams and/or slabs of the upper layer structure and the lower layer structure, respectively. Therefore, the above devices do not interfere with each other and convenient to maintain, and positions and functional parameters thereof can be set and selected reasonably.
摘要翻译：一种用于建筑物的隔振系统，包括隔振层，所述隔振层包括：上层结构，其由上梁和/或板坯和可移动基座组成，所述上层结构与所述建筑物的塔架联接; 下层结构由下梁和/或板坯和固定基座组成; 以及安装在上层结构和下层结构之间的隔振装置和弹性构件水平重置装置，其中隔振装置分别安装在可移动基座和固定基座之间，弹性构件水平 - 复位装置分别安装在上层结构和下层结构的梁和/或板之间。因此，上述装置不会彼此干扰并且维护方便，并且可以合理地设置和选择其位置和功能参数。

47. 发明申请

US20080083610A1 Sputtering Chamber Having Auxiliary Backside Magnet to Improve Etch Uniformity and Magnetron Producing Sustained Self Sputtering of Ruthenium and Tantalum 失效
标题翻译：具有辅助背面磁铁的溅射室，以提高蚀刻均匀性和制造钌和钽的持续自溅射的磁控管
公开(公告)号：US20080083610A1
公开(公告)日：2008-04-10
申请号：US11689720
申请日：2007-03-22
申请人： Xianmin Tang , Hua Chung , Rongjun Wang , Tza-Jing Gung , Praburam Gopalraja , Jick Yu , Hong Yang
发明人： Xianmin Tang , Hua Chung , Rongjun Wang , Tza-Jing Gung , Praburam Gopalraja , Jick Yu , Hong Yang
IPC分类号： C23C14/35
CPC分类号： C23C14/0641 , C23C14/345 , C23C14/35 , H01J37/3408 , H01J37/3455
摘要： A plasma sputter chamber and process for sputtering ruthenium and tantalum at low pressure or with self-sustained sputtering (SSS). The source magnetron is strongly unbalanced and of sufficient size to project the unbalanced magnetic field toward the wafer to increase the ionization probability. Sputter etch uniformity is increased by the use of an auxiliary magnet system rotating with the source magnetron but placed towards the center of rotation. It may be a larger, nearly balanced auxiliary magnetron with an outer polarity matching that of the source magnetron or an array of magnets of that polarity. An integrated process includes a directional deposition of the refractory metal and its nitride, a sputter etch, and a flash deposition.
摘要翻译：一种等离子体溅射室和用于在低压或自持溅射（SSS）下溅射钌和钽的工艺。源极磁控管是非常不平衡的，并且具有足够的尺寸以将不平衡磁场投射到晶片以增加电离概率。通过使用与源磁控管一起旋转但是朝向旋转中心放置的辅助磁体系统来增加溅射蚀刻均匀性。它可以是较大的，几乎平衡的辅助磁控管，其外极性与源极磁控管或该极性的磁体阵列的极性匹配。集成工艺包括难熔金属及其氮化物的定向沉积，溅射蚀刻和闪蒸沉积。

48. 发明申请

US20070210376A1 INTEGRATED CIRCUIT SYSTEM WITH DOUBLE DOPED DRAIN TRANSISTOR 有权
标题翻译：集成电路系统与双重漏极晶体管
公开(公告)号：US20070210376A1
公开(公告)日：2007-09-13
申请号：US11683655
申请日：2007-03-08
申请人： Yisuo Li , Gang Chen , Francis Benistant , Purakh Raj Verma , Hong Yang , Shao-fu Sanford Chu
发明人： Yisuo Li , Gang Chen , Francis Benistant , Purakh Raj Verma , Hong Yang , Shao-fu Sanford Chu
IPC分类号： H01L29/76
CPC分类号： H01L29/0847 , H01L29/0843 , H01L29/6659 , H01L29/66681 , H01L29/7393 , H01L29/7816 , H01L29/7833
摘要： An integrated circuit system includes a substrate, forming a gate over the substrate, forming a first drift region having a first counter diffused region and a source diffused region, the first drift region in the substrate adjacent a first side of the gate, and forming a second drift region having a second counter diffused region and a drain diffused region, the second drift region in the substrate adjacent a second side of the gate opposite the first side of the gate.
摘要翻译：集成电路系统包括：衬底，在衬底上形成栅极，形成具有第一反扩散区域和源极扩散区域的第一漂移区域，邻近栅极第一侧的衬底中的第一漂移区域，以及形成第二漂移区域，具有第二反扩散区域和漏扩散区域，所述衬底中的所述第二漂移区域邻近所述栅极的与所述栅极的第一侧相对的第二侧。

49. 发明申请

US20070209599A1 METHODS AND COMPOSITIONS FOR INCREASED PRODUCTIVITY IN ANIMALS 审中-公开
标题翻译：动物生产力提高的方法和组成
公开(公告)号：US20070209599A1
公开(公告)日：2007-09-13
申请号：US11684416
申请日：2007-03-09
申请人： Stephanie Block , Michael Cecava , Perry Doane , Mark Franklin , L. Kamel , Nathan Pyatt , Hong Yang
发明人： Stephanie Block , Michael Cecava , Perry Doane , Mark Franklin , L. Kamel , Nathan Pyatt , Hong Yang
IPC分类号： A01K5/00
CPC分类号： A01K29/00 , A23K20/111 , A23K50/00 , A23K50/10 , A23K50/20 , A23K50/30 , A23K50/60
摘要： Methods of improving performance and productivity in animals by feeding the animals an animal feed composition or animal feed supplement comprising a capsaicin product are disclosed. Methods and systems of feeding an animal comprising feeding the animal an animal feed composition or animal feed supplement comprising the capsaicin product are also disclosed. Feed compositions including a capsaicin product are also disclosed.
摘要翻译：公开了通过向动物喂养包含辣椒素产品的动物饲料组合物或动物饲料补充剂来提高动物的性能和生产力的方法。还公开了饲喂动物的方法和系统，包括给动物饲喂包含辣椒素产品的动物饲料组合物或动物饲料补充剂。还公开了包含辣椒素产品的饲料组合物。

50. 发明申请

US20070112038A1 Heterocyclic inhibitors of MEK and methods of use thereof 有权
标题翻译： MEK的杂环抑制剂及其使用方法
公开(公告)号：US20070112038A1
公开(公告)日：2007-05-17
申请号：US11435562
申请日：2006-05-17
申请人： Allison Marlow , Eli Wallace , Jeongbeob Seo , Joseph Lyssikatos , Hong Yang , James Blake
发明人： Allison Marlow , Eli Wallace , Jeongbeob Seo , Joseph Lyssikatos , Hong Yang , James Blake
IPC分类号： C07D213/84 , C07D213/63 , A61K31/44
CPC分类号： C07D213/78 , C07D209/46 , C07D213/80 , C07D213/82 , C07D215/48 , C07D231/56 , C07D237/24 , C07D237/28 , C07D237/32 , C07D239/74 , C07D401/04 , C07D401/06 , C07D413/04 , C07D413/14 , C07D417/04 , C07D471/04
摘要： Disclosed are compounds of the Formulas I and V and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
摘要翻译：公开了式I和V的化合物及其药学上可接受的盐和前药，其中R 1，R 2，R 7，R 7， SUP> 8和R 9，W，X和Y如说明书中所定义。这些化合物是MEK抑制剂，可用于治疗哺乳动物和炎性病症中的过度增殖性疾病，例如癌症和炎症。还公开了使用这些化合物治疗哺乳动物中过度增殖性疾病的方法和含有这些化合物的药物组合物。

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