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41. 发明申请

US20080268497A1 TREATMENT SOLUTION, METHOD FOR PRETREATMENT, METHOD FOR ACQUIRING INFORMATION AND METHOD FOR DETECTION 有权
标题翻译：治疗方案，预处理方法，获取信息的方法和检测方法
公开(公告)号：US20080268497A1
公开(公告)日：2008-10-30
申请号：US12098822
申请日：2008-04-07
申请人： Hiroyuki Hashimoto , Manabu Komatsu , Satoru Hatakeyama
发明人： Hiroyuki Hashimoto , Manabu Komatsu , Satoru Hatakeyama
IPC分类号： G01N1/30 , C12Q1/00
CPC分类号： G01N33/6848 , B82Y15/00 , G01N33/54313
摘要： The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens μm and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.
摘要翻译：本发明旨在提供用于鉴定直径为10至数十微米的每个电池中所含的蛋白质的类型的高灵敏度方法和所需的样品处理溶液。上述通过以下三个步骤实现：（1）用含有金颗粒和消化酶的水溶液处理患病组织的切片，并限制性地消化目的蛋白质，（2）测量片段肽的2维分布通过TOF-SIMS，以及（3）使用蛋白质组分析的结果并通过数值分析来显现病变组织切片中靶蛋白的二维分布。

42. 发明授权

US09086272B2 Profile measuring apparatus, method for manufacturing structure, and structure manufacturing system 有权
标题翻译：型材测量装置，结构制造方法和结构制造系统
公开(公告)号：US09086272B2
公开(公告)日：2015-07-21
申请号：US13273265
申请日：2011-10-14
申请人： Manabu Komatsu
发明人： Manabu Komatsu
IPC分类号： G01B11/30 , G01B11/14 , G01B11/24 , G01B11/25
CPC分类号： G01B11/25 , Y10T29/49 , Y10T29/53022
摘要： There is provided a profile measuring apparatus which measures a profile of an object including: a projection unit which projects a pattern on the object from a projection direction; a measurement unit, which is displaced at a difference position for the projection unit and takes an image of the pattern from a direction different from the projection direction to measure a position on a surface of the object based on an image data obtained with the taken image; an object-rotation unit which rotates the object in two directions; and a pattern-rotation unit which is connected to the projection unit so as to be able to rotate the pattern relative to the object-rotation unit.
摘要翻译：提供了一种测量物体的轮廓的轮廓测量装置，包括：投影单元，其从投影方向将物体投影到物体上; 测量单元，其在用于投影单元的差异位置处移位，并且从与投影方向不同的方向拍摄图案的图像，以基于利用拍摄图像获得的图像数据来测量对象的表面上的位置 ; 物体旋转单元，其在两个方向上旋转物体; 以及图案旋转单元，其连接到投影单元以能够相对于物体旋转单元旋转图案。

43. 发明授权

US08243308B2 Image processing apparatus for setting image quality mode and processing image data based on supplemental information 有权
标题翻译：用于基于补充信息设置图像质量模式和处理图像数据的图像处理装置
公开(公告)号：US08243308B2
公开(公告)日：2012-08-14
申请号：US12021562
申请日：2008-01-29
申请人： Manabu Komatsu
发明人： Manabu Komatsu
IPC分类号： H04N1/40 , G03F3/08 , G06K9/00
CPC分类号： H04N1/00204 , H04N1/00347 , H04N1/32358 , H04N2201/0039 , H04N2201/0065 , H04N2201/0094 , H04N2201/3222 , H04N2201/3223 , H04N2201/3242 , H04N2201/3243 , H04N2201/3278 , H04N2201/328 , H04N2201/3288
摘要： A first image-data processing unit unifies characteristics of input image data so that the image data is usable in an image writing unit and an external device, stores characteristic-unified image data in a storing unit, and changes an attribute of supplemental information according to an image input condition. When converting target image data into image data with characteristics suitable for outputting to the image writing unit and an external interface unit, a second image-data processing unit makes the stored image data be reusable in the image writing unit and the external device by performing an image processing based on the supplemental information.
摘要翻译：第一图像数据处理单元将输入图像数据的特征统一起来，使得图像数据可用于图像写入单元和外部设备，将特征统一的图像数据存储在存储单元中，并根据图像输入条件。当将目标图像数据转换成具有适于输出到图像写入单元和外部接口单元的特性的图像数据时，第二图像数据处理单元使存储的图像数据可以在图像写入单元和外部设备中重复使用，基于补充信息的图像处理。

44. 发明授权

US08072645B2 Image processing method and apparatus executing color correction based on color domain specified by user and determined relative to image source 有权
标题翻译：图像处理方法和装置，基于由用户指定的颜色域和相对于图像源确定的色彩校正
公开(公告)号：US08072645B2
公开(公告)日：2011-12-06
申请号：US12132881
申请日：2008-06-04
申请人： Manabu Komatsu
发明人： Manabu Komatsu
IPC分类号： H04N1/60
CPC分类号： H04N1/46
摘要： In an image processing method, a color corresponding to an input color image signal represented by an arbitrary RGB color space is detected and a requested color correction process is executed. A color domain according to property of the RGB color space is determined when determining a color domain based on a two-dimensional image signal representing a color plane converted from the input color image signal.
摘要翻译：在图像处理方法中，检测与由任意RGB颜色空间表示的输入彩色图像信号相对应的颜色，并执行所请求的颜色校正处理。基于代表从输入彩色图像信号转换的色彩平面的二维图像信号确定色域时，根据RGB颜色空间的特性确定色域。

45. 发明授权

US07868996B2 Liquid immersion microscope 失效
标题翻译：液浸式显微镜
公开(公告)号：US07868996B2
公开(公告)日：2011-01-11
申请号：US12083835
申请日：2006-10-18
申请人： Hiromasa Shibata , Manabu Komatsu , Toshio Uchikawa
发明人： Hiromasa Shibata , Manabu Komatsu , Toshio Uchikawa
IPC分类号： G03B27/52
CPC分类号： G02B21/33
摘要： To provide a liquid immersion microscope device enabling nondestructive liquid immersion observation of a substrate without deteriorating quality of the substrate. To attain this, a liquid immersion microscope device of the present invention includes a supporting unit supporting a substrate as an observation target, an objective lens of a liquid immersion type, a first supplying unit supplying ultrapure water as a liquid for observation to a gap between a tip of the objective lens and the substrate, a first draining unit draining the liquid for observation after observation of the substrate, a second supplying unit supplying a liquid for cleaning, which is different from the liquid for observation drained by the first draining unit, to an area, of the substrate, that has been in contact with the liquid for observation, and a second draining unit draining the liquid for cleaning after the substrate is cleaned.
摘要翻译：提供一种液晶显微镜装置，其能够对基板进行非破坏性液浸观察，而不会降低基板的质量。为此，本发明的液浸式显微镜装置包括：支撑单元，其支撑作为观察对象的基板，液浸型物镜;第一供给单元，其将超纯水作为观察用液体供给到第物镜的尖端和基板，在观察基板之后排出用于观察的液体的第一排水单元，供给与第一排水单元排出的观察用液体不同的清洗用液体的第二供给单元，与已经与用于观察的液体接触的基板的区域，以及在清洁基板之后排出用于清洁的液体的第二排出单元。

46. 发明授权

US07864437B2 Adaptor for microscope and microscope apparatus (microscope-use adaptor and microscope device) 有权
标题翻译：显微镜和显微镜装置适配器（显微镜使用适配器和显微镜装置）
公开(公告)号：US07864437B2
公开(公告)日：2011-01-04
申请号：US11817316
申请日：2006-02-23
申请人： Manabu Komatsu , Toshio Uchikawa , Hiromasa Shibata
发明人： Manabu Komatsu , Toshio Uchikawa , Hiromasa Shibata
IPC分类号： G02B21/02 , G03B27/52
CPC分类号： G02B21/33
摘要： A microscope apparatus efficiently supplies and collects a liquid for observation by local liquid immersion. The apparatus includes an objective of a liquid immersion system, a discharging member for discharging the liquid between a front edge of the objective and a substrate, and a sucking member for sucking the liquid. Inclined faces are provided respectively in two positions adjacent to the front edge in the periphery of the objective, and protruded portions are provided in positions adjacent to the inclined faces. An aperture portion bounded by the protruded portions and the substrate is formed at the side face. The discharging member includes a tubular member provided on the inclined face for discharging the liquid. The sucking member includes another tubular member for sucking the liquid while taking in air via the aperture portion.
摘要翻译：显微镜装置通过局部液浸有效地供给和收集用于观察的液体。该装置包括液浸系统的目的，用于在物体的前边缘和基板之间排出液体的排出构件和用于吸取液体的抽吸构件。倾斜面分别设置在与物镜周边的前缘相邻的两个位置，突出部分设置在与倾斜面相邻的位置。在侧面形成有由突出部和基板界定的开口部。排出构件包括设置在倾斜面上用于排出液体的管状构件。抽吸构件包括用于在通过孔部分吸入空气的同时吸取液体的另一个管状构件。

47. 发明申请

US20080259446A1 Adaptor for Microscope and Microscope Apparatus (Microscope-Use Adaptor and Microscope Device) 有权
标题翻译：显微镜和显微镜装置适配器（显微镜使用适配器和显微镜装置）
公开(公告)号：US20080259446A1
公开(公告)日：2008-10-23
申请号：US11817316
申请日：2006-02-23
申请人： Manabu Komatsu , Toshio Uchikawa , Hiromasa Shibata
发明人： Manabu Komatsu , Toshio Uchikawa , Hiromasa Shibata
IPC分类号： G02B21/26
CPC分类号： G02B21/33
摘要： Providing a microscope apparatus supplying efficiently and collecting a liquid upon observation with local liquid immersion. The apparatus including an objective of a liquid immersion system, discharging means discharging the liquid between a front edge of the objective and a substrate, and sucking means sucking the liquid. Inclined faces are provided respectively in two positions adjacent to the front edge in the periphery of the objective, and protruded portions are provided in positions adjacent to the inclined faces. An aperture portion surrounded by the protruded portions and the substrate is formed in the side face. The discharging means includes a tubular member provided on the inclined face and the liquid is discharged by using the tubular member. The sucking means includes a tubular member and the liquid is sucked while taking in the air via the aperture portion by use of the tubular member.
摘要翻译：提供一种显微镜装置，在用局部液浸观察时有效提供并收集液体。该装置包括液浸系统的目的，将物体的前边缘与基板排出液体的排出装置以及吸入液体的吸引装置。倾斜面分别设置在与物镜周边的前缘相邻的两个位置，突出部分设置在与倾斜面相邻的位置。在侧面形成由突出部和基板包围的开口部。排出装置包括设置在倾斜面上的管状构件，并且通过使用管状构件排出液体。抽吸装置包括管状构件，并且通过使用管状构件经由孔部吸入空气而吸入液体。

48. 发明申请

US20080037036A1 Image processing apparatus 有权
标题翻译：图像处理装置
公开(公告)号：US20080037036A1
公开(公告)日：2008-02-14
申请号：US11890640
申请日：2007-08-07
申请人： Atsushi Togami , Tomoyuki Yoshida , Toshiya Hikita , Takeharu Tone , Shuji Kimura , Takumi Nozawa , Toshimi Yamamura , Akira Murakata , Satoshi Ohkawa , Manabu Komatsu , Yasunobu Shirata , Hiroyuki Kawamoto , Yukihiko Tamura
发明人： Atsushi Togami , Tomoyuki Yoshida , Toshiya Hikita , Takeharu Tone , Shuji Kimura , Takumi Nozawa , Toshimi Yamamura , Akira Murakata , Satoshi Ohkawa , Manabu Komatsu , Yasunobu Shirata , Hiroyuki Kawamoto , Yukihiko Tamura
IPC分类号： G06F3/12
CPC分类号： H04N1/33307 , H04N1/00204 , H04N1/00347 , H04N1/33392 , H04N2201/0015 , H04N2201/0067 , H04N2201/0068 , H04N2201/0087 , H04N2201/0091 , H04N2201/0093 , H04N2201/0094 , H04N2201/33378
摘要： An image processing apparatus in which the reusability of digital image data is improved is disclosed. The apparatus includes an image reading unit reading a draft and obtaining the digitized image data; an image writing unit printing image data on a transfer paper; a recording unit recording image data and attached information of the image data; an external I/F unit transmitting and receiving image data and attached information of the image data; a first and a second image data processing units processing the image data from the image reading unit and the recording unit, respectively; and a bus controlling unit connecting each of the units. The first and the second image data processing units match the characteristics of the image data to prescribed characteristics so that the matched image data can be usable for both the image writing unit and the external device.
摘要翻译：公开了一种提高数字图像数据的可重用性的图像处理装置。该装置包括读取草图并获得数字化图像数据的图像读取单元; 图像写入单元，将转印纸上的图像数据打印; 记录单元，记录图像数据和附加的图像数据的信息; 外部I / F单元发送和接收图像数据和附加的图像数据的信息; 第一和第二图像数据处理单元分别处理来自图像读取单元和记录单元的图像数据; 以及连接每个单元的总线控制单元。第一和第二图像数据处理单元将图像数据的特性与规定的特性相匹配，使得匹配的图像数据能够用于图像写入单元和外部设备。

49. 发明申请

US20070226692A1 IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING METHOD 审中-公开
标题翻译：图像处理装置和图像处理方法
公开(公告)号：US20070226692A1
公开(公告)日：2007-09-27
申请号：US11689762
申请日：2007-03-22
申请人： Takumi NOZAWA , Hiroyuki Kawamoto , Toshiya Hikita , Tomoyuki Yoshida , Shuji Kimura , Manabu Komatsu , Takeharu Tone , Toshimi Yamamura , Satoshi Ohkawa , Atsushi Togami , Yasunobu Shirata , Akira Murakata , Yukihiko Tamura
发明人： Takumi NOZAWA , Hiroyuki Kawamoto , Toshiya Hikita , Tomoyuki Yoshida , Shuji Kimura , Manabu Komatsu , Takeharu Tone , Toshimi Yamamura , Satoshi Ohkawa , Atsushi Togami , Yasunobu Shirata , Akira Murakata , Yukihiko Tamura
IPC分类号： G06F9/44
CPC分类号： G06F11/3664 , H04N1/00204 , H04N1/00973 , H04N1/32561 , H04N2201/0094
摘要： An image processing apparatus is disclosed. The image processing apparatus includes: an image processing unit configured to perform a plurality of image processes on image data that is input to the image processing apparatus; a unit configured to receive a specified function; an image debugging interface unit configured to output the image data on which an image process, of the plurality of image processes, corresponding to the specified function has been performed to an external apparatus in a debugging mode; and an image output unit configured to output the image data on which the image process corresponding to the specified function and following at least one image process of the plurality of image processes have been performed in the debugging mode.
摘要翻译：公开了一种图像处理装置。图像处理装置包括：图像处理单元，被配置为对输入到图像处理装置的图像数据执行多个图像处理; 被配置为接收指定功能的单元; 图像调试接口单元，被配置为在调试模式中将对应于所指定的功能的多个图像处理中的图像处理的图像数据输出到外部设备; 以及图像输出单元，被配置为在调试模式中输出在其上执行与所指定的功能相对应的图像处理并遵循多个图像处理中的至少一个图像处理的图像数据。

50. 发明申请

US20050237544A1 Method, computer readable medium and apparatus for converting color image resolution 有权
标题翻译：方法，计算机可读介质和用于转换彩色图像分辨率的装置
公开(公告)号：US20050237544A1
公开(公告)日：2005-10-27
申请号：US11157910
申请日：2005-06-22
申请人： Hiroaki Suzuki , Manabu Komatsu
发明人： Hiroaki Suzuki , Manabu Komatsu
IPC分类号： G06K9/00 , G06K9/32 , G06K15/02 , G06T3/40 , H04N1/393 , H04N1/40 , H04N1/56 , H04N1/60
CPC分类号： H04N1/3935 , G06T3/4015 , G09G5/02 , G09G2340/0407 , H04N1/40068 , H04N1/58
摘要： A method, computer readable medium and apparatus for converting color image resolution include inputting an image enlarging ratio, inputting target pixel data of an image in a first color space to be enlarged in a sequence, sampling reference pixels including the target pixel and pixels at least one of which links to the target pixel, and converting the reference pixel data into a second color space data. Other functions include extracting image feature quantities from the reference pixel data, selecting one of a plurality of pixel multiplying methods according to the extracted image feature quantities, multiplying the target pixel by the selected image multiplying method with an integer value based on the input image enlarging ratio, and outputting pixel data that have been generated by the target pixel multiplying step in a sequence.
摘要翻译：一种用于转换彩色图像分辨率的方法，计算机可读介质和装置，包括：输入图像放大率，输入第一颜色空间中的图像的目标像素数据以便按序列放大，至少包括目标像素和像素的参考像素其中一个链接到目标像素，并将参考像素数据转换为第二颜色空间数据。其他功能包括从参考像素数据提取图像特征量，根据提取的图像特征量选择多个像素乘法方法中的一个，根据所输入的图像放大将目标像素乘以所选择的图像乘法方法与整数值并按顺序输出由目标像素乘法步骤生成的像素数据。

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