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41. 发明授权

US4212938A Reagent and method for the determination of cholesterol 失效
标题翻译：用于测定胆固醇的试剂和方法
公开(公告)号：US4212938A
公开(公告)日：1980-07-15
申请号：US360515
申请日：1973-05-15
申请人： Wolfgang Gruber , Hans U. Bergmeyer , Erich Bernt , Alexander Hagen , Peter Roeschlau , Gunter Lang , Klaus Beaucamp
发明人： Wolfgang Gruber , Hans U. Bergmeyer , Erich Bernt , Alexander Hagen , Peter Roeschlau , Gunter Lang , Klaus Beaucamp
IPC分类号： G01N33/92 , A61B10/00 , C07J9/00 , C12Q1/26 , C12Q1/60 , G01N33/15 , G01N33/48 , C12Q1/50
CPC分类号： C12Q1/60
摘要： Cholesterol is determined by incubating a sample suspected of containing cholesterol in an aqueous medium with cholesterol oxidase and determining either the oxygen consumption, the hydrogen peroxide formed, or cholestenone, as a measure of the initial cholesterol content; reagent compositions comprising cholesterol oxidase and a system for the determination of H.sub.2 O.sub.2 or for the determination of cholestenone are provided.
摘要翻译：胆固醇通过将怀疑含有胆固醇的样品置于水性介质中与胆固醇氧化酶并测定氧消耗，形成的过氧化氢或胆碱酯酶作为初始胆固醇含量的量度来确定; 提供了包含胆固醇氧化酶的试剂组合物和用于测定H 2 O 2或测定胆碱酯的系统。

42. 发明授权

US4164448A Activation of cholesterol oxidase for cholesterol assay 失效
标题翻译：胆固醇氧化酶激活胆固醇测定
公开(公告)号：US4164448A
公开(公告)日：1979-08-14
申请号：US768530
申请日：1977-02-14
申请人： Peter Roeschlau , Gunter Lang , Klaus Beaucamp , Erich Bernt , Wolfgang Gruber
发明人： Peter Roeschlau , Gunter Lang , Klaus Beaucamp , Erich Bernt , Wolfgang Gruber
IPC分类号： C12N9/04 , C12Q1/60 , C07G7/02 , G01N31/14
CPC分类号： C12N9/0006 , C12Q1/60
摘要： Cholesterol oxidase free of unstabilizing residual traces of detergent is activated by adding to the cholesterol oxidase, before use thereof, at least one surface-active compound with lipophilic and hydrophilic properties. Diagnostic agents for determining cholesterol comprising cholesterol oxidase, a hydrogen peroxide detection system, a buffer, and at least one surface-active compound having lipophilic and hydrophilic properties are provided.
摘要翻译：没有不稳定残留痕量的洗涤剂的胆固醇氧化酶通过在使用前加入至少一种具有亲油性和亲水性的表面活性化合物来激活胆固醇氧化酶。提供了用于测定胆固醇的诊断剂，其包含胆固醇氧化酶，过氧化氢检测系统，缓冲液和至少一种具有亲油性和亲水性的表面活性化合物。

43. 发明授权

US4113933A Manufacture of homopolymers and copolymers of .alpha.-monoolefins 失效
标题翻译： “ - 烯烃的共聚物和共聚物的制备”
公开(公告)号：US4113933A
公开(公告)日：1978-09-12
申请号：US762858
申请日：1977-01-27
申请人： Gunther Schweier , Erich Kolk , Heinz Mueller-Tamm , Hans Frielingsdorf , Robert Bachl , Wolfgang Gruber
发明人： Gunther Schweier , Erich Kolk , Heinz Mueller-Tamm , Hans Frielingsdorf , Robert Bachl , Wolfgang Gruber
IPC分类号： C08F10/00 , C08F4/02 , C08F10/02
CPC分类号： C08F10/00
摘要： A process for the manufacture of homopolymers and copolymers of .alpha.-monoolefins of 2 to 6 carbon atoms by polymerizing the monomer or monomers by means of a Ziegler catalyst system comprising (1) a catalyst component containing titanium and (2) a particular compound of aluminum, magnesium or zinc, the atomic ratio of titanium from catalyst component (1) to metal (Me) from catalyst component (2) being from 1 : 0.1 to 1 : 500, wherein the titanium-containing catalyst component (1) employed is the solid-phase product (VI) obtained by (1.1) first bringing into contact (1.1.1) a particular finely divided, porous, inorganic oxidic material (I) and (1.1.2) a particular aluminum compound (II) dissolved in an organic solvent, to form a solid-phase product (III) and (1.2) then bringing into contact (1.2.1) the solid-phase product (III) obtained from stage (1.1) and (1.2.2) a solution (IV) which is obtained on bringing together (IVa) 100 parts by weight of a particular alcohol, (IVb) from 0.01 to 6 parts by weight (calculated as titanium) of a titanium trihalide and (IVc) from 0.01 to 4 parts by weight (calculated as magnesium) of a magnesium compound which is soluble in the alcohol (IVa), to form a dispersion (V), and evaporating the dispersion (V) until it has a dry consistency, thus forming the solid-phase product (VI). The new process is particularly advantageous for the manufacture of homopolymers and copolymers having, for example, particularly advantageous morphological properties.

44. 发明授权

US4066508A Process and reagent for determining triglycerides 失效
标题翻译：用于测定TRIGLYCERIDES的方法和试剂
公开(公告)号：US4066508A
公开(公告)日：1978-01-03
申请号：US707455
申请日：1976-07-21
申请人： Elli Rauscher , Erich Bernt , Wolfgang Gruber , Helmut Determann
发明人： Elli Rauscher , Erich Bernt , Wolfgang Gruber , Helmut Determann
IPC分类号： C12N9/20 , C11C1/04 , C12Q1/02 , C12Q1/44 , C12Q1/48 , C12Q1/61 , G01N33/53 , C12K1/00
CPC分类号： C12Q1/48 , C12Q1/44 , C12Q1/61 , Y10S435/939
摘要： Triglycerides are determined by enzymatic saponification with lipase in a buffer in the presence of a carboxylesterase and an alkali metal or alkaline earth metal (10-15 carbon atom) alkyl sulfate, in the additional presence of a compound of the general formula RO(CH.sub.2 CH.sub.2).sub.n H, in which R is alkyl or alkenyl containing 14 to 20 carbon atoms and n is a number of from 7 to 20; this determination prevents turbidity and does not disadvantageously influence enzyme activity.

45. 发明授权

US4048414A Manufacture of olefin polymers 失效
标题翻译：烯烃聚合物的制造
公开(公告)号：US4048414A
公开(公告)日：1977-09-13
申请号：US657863
申请日：1976-02-13
申请人： Hans Frielingsdorf , Wolfgang Gruber , Heinz Mueller-Tamm
发明人： Hans Frielingsdorf , Wolfgang Gruber , Heinz Mueller-Tamm
IPC分类号： C08F4/00 , C08F4/06 , C08F10/00 , C08F4/02 , C08F4/24
CPC分类号： C08F10/00
摘要： A process for the manufacture of olefin polymers by polymerization of monoolefins using a silicic xerogel/chromium trioxide catalyst obtained by (1) synthesizing a particulate silicic xerogel, (2) doping said xerogel with chromium trioxide or a chromium compound capable of converting to chromium trioxide under the conditions of stage (3) and (3) heating the resulting product in a gas stream containing oxygen. The silicic xerogel/chromium trioxide catalyst used is one which has been obtained by (1) synthesizing the silicic xerogel in the first stage by (1.1) starting with a silicic hydrogel having a relatively high solids content, (1.2) extracting water from said hydrogel by means of an alkanol and/or alkanone until the organic liquid absorbs no further water, (1.3) extracting the organic liquid used in stage (1.2) from the resulting dehydrated gel saturated with said organic liquid by means of a hydrocarbon or oxohydrocarbon until said hydrocarbon or oxohydrocarbon absorbs no further organic liquid from stage (1.2), and (1.4) drying the resulting dehydrated gel saturated with hydrocarbon or oxohydrocarbon (xerogel formation), and (2) doping said xerogel in the second stage with the desired amount of chromium from a solution of chromium trioxide in an alkanone or solution of a chromium compound capable of converting to chromium trioxide under the conditions of stage (3) in an alkanol or alkanone with evaporation of the solvent.
摘要翻译：一种通过使用（1）合成硅氧烷干燥剂获得的硅干燥剂/三氧化铬催化剂聚合单烯烃的方法，（2）用三氧化铬或能够转化成三氧化铬的铬化合物掺杂干燥剂在阶段（3）和（3）的条件下，将所得产物加热到含氧的气流中。所使用的硅干凝胶/三氧化铬催化剂是通过（1）通过（1.1）由具有相对高的固体含量的硅水凝胶合成硅酸凝胶得到的，（1.2）从所述水凝胶中提取水通过烷醇和/或烷酮直到有机液体不再吸收其他水，（1.3）从所得到的用烃或氧代烃饱和的有机液体的脱水凝胶中提取阶段（1.2）中使用的有机液体，直到所述碳氢化合物或氧代烃不会从阶段（1.2）吸收进一步的有机液体，和（1.4）干燥所得到的用烃或氧代烃饱和的脱水凝胶（干凝胶形成），和（2）在第二阶段用所需量的铬掺杂所述干凝胶在三烷基铬溶液中，在烷烃或烷烃或碱的阶段（3）的条件下，可以在烷酮或能够转化成三氧化铬的铬化合物的溶液中，无溶剂蒸发。

46. 发明授权

US4042770A Manufacture of olefin polymers 失效
标题翻译：烯烃聚合物的制造
公开(公告)号：US4042770A
公开(公告)日：1977-08-16
申请号：US631642
申请日：1975-11-13
申请人： Robert Bachl , Hans Frielingsdorf , Wolfgang Gruber , Heinz Mueller-Tamm , Leonhard Gonsior
发明人： Robert Bachl , Hans Frielingsdorf , Wolfgang Gruber , Heinz Mueller-Tamm , Leonhard Gonsior
IPC分类号： C08F4/00 , C08F4/06 , C08F10/00 , C08F4/02 , C08F4/24
CPC分类号： C08F10/00 , Y02P20/52
摘要： This invention relates to a process for the manufacture of olefin polymers by polymerization of monoolefins with the aid of a silicic xerogel/chromium trioxide catalyst obtained by (1) synthesizing a particulate silicic xerogel, (2) doping this xerogel with chromium trioxide or a chromium compound which converts to chromium trioxide under conditions of stage (3) and (3) maintaining the resulting product at an elevated temperature in a water-free oxygen-containing stream of gas. The characteristic feature of the process of the invention is that the silicic xerogel/chromium trioxide catalyst used is one obtained by (1) synthesizing the silicic xerogel in the first stage as follows: (1.1) taking an aqueous solution of a sodium silicate, (1.2) substituting substantially all of the sodium ions contained in said solution by hydrogen ions by means of an ion exchanger, (1.3) introducing a water-soluble aluminum salt into the resulting aqueous silicic acid solution, (1.4) adjusting the pH of the solution obtained in stage (1.3) to from 0.1 to 3.5, if necessary, (1.5) adjusting the solution obtained in (1.3) or (1.4) to a pH of from 4 to 12 by means of a nitrogen-base compound, (1.6) extracting the product forming the solid phase in stage (1.5) (silicic hydrogel) by means of an alkanol and/or alkanone until the organic liquid absorbs no more water and, finally, (1.7) drying the dehydrated gel saturated with organic liquid resulting from stage (1.6) (xerogel formation). This process makes it possible to obtain polymers having a satisfactory particle size distribution and a favorable melt index.
摘要翻译：本发明涉及一种通过使用（1）合成硅氧烷干凝胶得到的硅胶干凝胶/三氧化铬催化剂，通过单烯烃的聚合制备烯烃聚合物的方法，（2）将这种干凝胶与三氧化铬或铬在阶段（3）和（3）的条件下转化成三氧化铬的化合物在无水的含氧气流中保持所得产物在升高的温度。本发明方法的特征在于，使用的硅干燥剂/三氧化铬催化剂是通过（1）在第一阶段合成硅干凝胶得到的催化剂如下：（1.1）取硅酸钠水溶液（ 1.2）通过离子交换器用氢离子基本上全部取代所述溶液中所含的所有钠离子，（1.3）将水溶性铝盐引入所得水性硅酸溶液中，（1.4）调节溶液的pH （1.3）中得到的化合物为0.1至3.5，如果需要，（1.5）通过氮碱化合物将（1.3）或（1.4）中获得的溶液调节至4至12的pH，（1.6）通过链烷醇和/或烷酮萃取在阶段（1.5）（硅水凝胶）中形成固相的产物，直到有机液体吸收不再多的水，最后（1.7）干燥由有机液体饱和的脱水凝胶阶段（1.6）（干凝胶形成）。该方法可以获得具有令人满意的粒度分布和良好熔融指数的聚合物。

47. 发明授权

US3979447A .gamma.-Glutamyl-4-nitroanilide compounds 失效
标题翻译： {65-氨基-4-硝基苯胺化合物
公开(公告)号：US3979447A
公开(公告)日：1976-09-07
申请号：US419455
申请日：1973-11-27
申请人： Erich Bernt , Wolfgang Gruber , Erich Haid , Fritz Stahler , August Wilhelm Wahlefeld , Gunter Weimann
发明人： Erich Bernt , Wolfgang Gruber , Erich Haid , Fritz Stahler , August Wilhelm Wahlefeld , Gunter Weimann
IPC分类号： G01N33/50 , C07C67/00 , C07C237/04 , C07C301/00 , C07C303/22 , C07C303/32 , C07C309/46 , C07C309/51 , C12Q1/48 , C07C103/50
CPC分类号： C12Q1/48
摘要： .gamma.-Glutamyl-4-nitroanilide compounds of the formula ##SPC1##Wherein R is a .gamma.-glutamyl radical and X is an acid group, and salts of such compounds, are used to determine .gamma.-glutamyltranspeptidase by contacting a sample suspected of containing .gamma.-glutamyltranspeptidase with said compound and glycylglycine and determining the liberation of the resulting p-nitroaniline compound as a measure of the .gamma.-glutamyltranspeptidase activity initially present in the sample.
摘要翻译：通过将疑似含有γ-谷氨酰基转肽酶的样品与含有γ-谷氨酰基转肽酶的样品接触的γ-谷氨酰基-4-硝基苯胺化合物，其中WHEREIN R是γ-谷氨酰基，X是酸基，并且这些化合物的盐用于测定γ-谷氨酰转肽酶所述化合物和甘氨酰甘氨酸，并确定所得到的对硝基苯胺化合物的释放作为样品中最初存在的γ-谷氨酰转肽酶活性的量度。

48. 发明授权

US3977944A Enzyme-kinetic determination of the concentration of a substrate 失效
标题翻译：酶 - 动力学测定底物的浓度
公开(公告)号：US3977944A
公开(公告)日：1976-08-31
申请号：US511402
申请日：1974-10-02
申请人： Reinhard Muller-Matthesius , Wolfgang Gruber
发明人： Reinhard Muller-Matthesius , Wolfgang Gruber
IPC分类号： G01N21/75 , C12Q1/00 , C12Q1/32 , C12Q1/54 , C12Q1/62 , C12K1/04 , G01N31/14 , G01N33/16
CPC分类号： C12Q1/00 , C12Q1/32 , C12Q1/54 , C12Q1/62
摘要： Enzyme-kinetic determination of the concentration of an enzyme substrate which is acted on during an enzymatic reaction is carried out by adding at least one competitive inhibitor to an enzymatic reaction medium to bring the ratio of the substrate concentration C.sub.3 to the apparent Michaelis constant K'.sub.M to 0.2:1 or less, homogenizing the medium and determining the rate change of the enzymatic reaction at certain intervals of time.
摘要翻译：通过在酶促反应介质中加入至少一种竞争性抑制剂以使底物浓度C3与表观米氏常数K'的比例来进行酶反应过程中酶底物浓度的酶 - 动力学测定， M至0.2：1或更低，均化培养基并确定酶反应的速率变化在一定的时间间隔。

49. 发明授权

US08350460B2 Fluorescent coating for high output lamps with color temperatures of less than 2700 kelvin 失效
标题翻译：高输出灯的荧光涂层，色温低于2700开
公开(公告)号：US08350460B2
公开(公告)日：2013-01-08
申请号：US12312007
申请日：2007-10-22
申请人： Claudia Castiglioni , Wolfgang Gruber , Armin Konrad
发明人： Claudia Castiglioni , Wolfgang Gruber , Armin Konrad
IPC分类号： H01J63/04 , C09K11/78
CPC分类号： H01J61/44 , C09K11/778 , C09K11/7787
摘要： The invention relates to a fluorescent coating for Hg low-pressure discharge lamps, comprising a fluorescent composition from at least one green fluorescent material emitting in the green spectral range, especially a Tb-and/or Eu-doped green fluorescent material, and a red fluorescent material emitting in the red spectral range, especially a Eu and/or Mn red fluorescent material. The invention is characterized in that a further fluorescent material is present which is adapted to absorb UV Hg and Hg-Vis radiation.
摘要翻译：本发明涉及一种用于Hg低压放电灯的荧光涂层，其包括由绿色光谱范围内发出的至少一种绿色荧光材料的荧光组合物，特别是Tb掺杂和/或掺杂Eu的绿色荧光材料，以及红在红色光谱范围内发射的荧光材料，特别是Eu和/或Mn红色荧光材料。本发明的特征在于存在适于吸收UV Hg和Hg-Vis辐射的另外的荧光材料。

50. 发明申请

US20090053854A1 MEMORY CIRCUIT ARRANGEMENT AND METHOD FOR THE PRODUCTION THEREOF 有权
公开(公告)号：US20090053854A1
公开(公告)日：2009-02-26
申请号：US12258742
申请日：2008-10-27
申请人： Wolfgang Gruber , Ronald Kakoschke , Thomas Schweizer , Dominik Wegertseder
发明人： Wolfgang Gruber , Ronald Kakoschke , Thomas Schweizer , Dominik Wegertseder
IPC分类号： H01L21/00
CPC分类号： G11C5/025 , H01L25/18 , H01L2924/0002 , H01L2924/00
摘要： A memory circuit arrangement and fabrication method thereof are presented in which the parts of the memory circuit arrangement are situated on two different substrates. An integrated memory cell array is situated on one substrate. An integrated control circuit that controls access to the memory cells is situated on the other (logic circuit) substrate. The control circuit controls sequences when reading, writing or erasing content of a memory cell. The logic circuit substrate also contains a CPU and encryption coprocessor. The memory circuit contains a sense amplifier, with the aid of which the memory state of a memory cell can be determined, and a decoding circuit that selects a word or bit line.

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