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41. 发明申请

US20110301641A1 Systems And Methods For Treating Septal Defects 审中-公开
标题翻译：系统和方法治疗间隔缺损
公开(公告)号：US20110301641A1
公开(公告)日：2011-12-08
申请号：US13214451
申请日：2011-08-22
申请人： Ryan Abbott , W. Martin Belef , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William Gray , Dean Carson
发明人： Ryan Abbott , W. Martin Belef , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William Gray , Dean Carson
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B17/0644 , A61B17/068 , A61B17/29 , A61B2017/00292 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00668 , A61B2017/00867 , A61B2017/06052 , A61B2017/061 , A61B2017/0649 , A61B2017/2912 , A61B2090/0811
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus, devices for controlling delivery of the treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, and a proximal control device for controlling delivery of the implantable apparatus, among others.
摘要翻译：提供一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置，用于控制治疗装置的输送的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，以及用于控制可植入装置的输送的近端控制装置等。

42. 发明授权

US07828817B2 Apparatus and methods for delivering a closure device 有权
标题翻译：用于传送闭合装置的装置和方法
公开(公告)号：US07828817B2
公开(公告)日：2010-11-09
申请号：US11198811
申请日：2005-08-04
申请人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
发明人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
IPC分类号： A61B17/08
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/064 , A61B17/128 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641
摘要： An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.
摘要翻译：用于递送夹子以封闭通过组织的开口的装置包括护套和载体组件，其包括可在护套上滑动的夹子。致动器组件可连接到护套，并且可伸缩的致动器构件从手柄延伸，所述手柄可连接到托架组件，用于沿着护套推进托架组件。致动器组件上的密封件包括可以部署在鞘的远端之外的花键，并且在展开夹子之前扩展成横向扩展构型以定位护套。致动器构件包括配合的棘爪，当托架组件沿着护套到达预定位置时，选择性地释放致动器构件，用于将夹子从承载器组件展开，并且在使用夹子之后使花键折叠以允许移除装置。

43. 发明授权

US06942674B2 Apparatus and methods for delivering a closure device 有权
公开(公告)号：US06942674B2
公开(公告)日：2005-09-13
申请号：US10081723
申请日：2002-02-21
申请人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
发明人： W. Martin Belef , William N. Aldrich , Michael T. Carley , Ronald J. Jabba , Stephen M. Salmon , Anthony Pantages , Javier Sagastegui
IPC分类号： A61B17/00 , A61B17/064 , A61B17/08 , A61B17/128 , A61B19/00 , A61B17/10
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/064 , A61B17/128 , A61B90/39 , A61B2017/00004 , A61B2017/00637 , A61B2017/00668 , A61B2017/00672 , A61B2017/00862 , A61B2017/0641
摘要： An apparatus for delivering a clip to close an opening through tissue includes a sheath and a carrier assembly including a clip therein that is slidable on the sheath. An actuator assembly is connectable to the sheath, and telescoping actuator members extend from the handle that are connectable to the carrier assembly for advancing the carrier assembly along the sheath. An obturator on the actuator assembly includes splines that may be deployed beyond a distal end of the sheath, and expanded to a transverse expanded configuration for positioning the sheath before deploying the clip. The actuator members include cooperating detents that selectively release the actuator members as the carrier assembly reaches predetermined positions along the sheath for deploying the clip from the carrier assembly, and that collapse the splines to allow removal of the apparatus after deploying the clip.

44. 发明授权

US06846319B2 Devices for sealing openings through tissue and apparatus and methods for delivering them 有权
标题翻译：用于通过组织和装置密封开口的装置和用于传送它们的方法
公开(公告)号：US06846319B2
公开(公告)日：2005-01-25
申请号：US09738431
申请日：2000-12-14
申请人： Richard S. Ginn , Stephen M. Salmon , Ronald J. Jabba
发明人： Richard S. Ginn , Stephen M. Salmon , Ronald J. Jabba
IPC分类号： A61B10/00 , A61B17/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B2010/0003 , A61B2017/00004 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672 , A61B2017/00898
摘要： An apparatus for sealing a passage through tissue includes an elongate shaft and a cylindrical plug disposed on a distal end of the shaft, the plug including a helical thread on its outer surface. Intestinal submucosa may be secured to the plug, e.g., in a cavity in its distal end, that may be delivered into the passage. Alternatively, the plug may be formed from a bioabsorbable material and may be released from the shaft within the passage. The plug is threaded into the passage, thereby engaging the tissue to seal the passage. The shaft is rotated until it engages a blood vessel within the tissue while monitoring blood flow through the vessel. The shaft is rotated to thread the plug into the passage until blood flow ceases through the vessel, whereupon rotation of the shaft is reversed to back the plug until blood flow through the vessel resumes.
摘要翻译：用于密封通过组织的通道的装置包括细长轴和设置在轴的远端上的圆柱塞，该塞在其外表面上包括螺旋形螺纹。肠粘膜下层可以固定到栓塞，例如在其远端的空腔中，其可以被输送到通道中。或者，插塞可以由生物可吸收材料形成，并且可以在通道内从轴释放。塞子被拧入通道中，从而接合组织以密封通道。旋转轴直到其与组织内的血管接合，同时监测通过血管的血流。轴被旋转以将塞子螺纹连接到通道中，直到血流停止通过血管，由此轴的旋转被反向以回到塞子，直到通过血管的血液流动恢复。

45. 发明授权

US06827693B2 System and method for intraluminal imaging 有权
公开(公告)号：US06827693B2
公开(公告)日：2004-12-07
申请号：US10165692
申请日：2002-06-07
申请人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
发明人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
IPC分类号： A61B500
CPC分类号： A61B8/12 , A61B8/4461 , A61M25/00 , A61M39/10
摘要： An improved catheter system having an ultrasonic imaging transducer coupled to a drive cable disposed within a lumen of a flexible tubular catheter body. An improvement including a reconfiguration of the ferrites in the hub assembly, such that the need for the gap between the ferrites is removed. A strain relief member is provide to increase the strength of the electrical transmission lines to enable them to withstand the tensile forces caused by either flushing and/or pull-back operations. A device which allows the electrical transmission lines to extend their length when placed in tension may also be employed to provide strain relief to the electrical transmission lines. Another improvement includes a counter-wound coil structure, which may either expand or contract as the drive cable is being rotated to strengthen the drive cable. The distal tip of the catheter body may be redesigned to provide a lumen which allows for the release of flushing fluids through a distal port in the guidewire lumen.

46. 发明授权

US06793634B2 System and method for intraluminal imaging 有权
标题翻译：管腔内成像系统及方法
公开(公告)号：US06793634B2
公开(公告)日：2004-09-21
申请号：US09862811
申请日：2001-05-22
申请人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
发明人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
IPC分类号： A61B814
CPC分类号： A61B8/12 , A61B8/4461
摘要： An improved catheter system having an ultrasonic imaging transducer coupled to a drive cable disposed within a lumen of a flexible tubular catheter body. An improvement including a reconfiguration of the ferrites in the hub assembly, such that the need for the gap between the ferrites is removed. A strain relief member is provide to increase the strength of the electrical transmission lines to enable them to withstand the tensile forces caused by either flushing and/or pull-back operations. A device which allows the electrical transmission lines to extend their length when placed in tension may also be employed to provide strain relief to the electrical transmission lines. Another improvement includes a counter-wound coil structure, which may either expand or contract as the drive cable is being rotated to strengthen the drive cable. The distal tip of the catheter body may be redesigned to provide a lumen which allows for the release of flushing fluids through a distal port in the guidewire lumen.
摘要翻译：一种改进的导管系统，其具有耦合到设置在柔性管状导管主体的内腔内的驱动电缆的超声成像换能器。包括轮毂组件中的铁氧体的重新配置的改进，使得铁氧体之间的间隙的需要被去除。提供应变消除构件以增加电力传输线的强度，使得它们能够承受由冲洗和/或拉回操作引起的张力。允许电气传输线在放置在张力时延长其长度的装置也可用于向电气传输线提供应变消除。另一个改进包括一个反绕线圈结构，其可以随着驱动电缆的旋转而膨胀或收缩，以加强驱动电缆。可以重新设计导管主体的远侧末端以提供允许通过导丝管腔中的远端端口释放冲洗流体的内腔。

47. 发明授权

US06626852B2 System for intraluminal imaging 失效
公开(公告)号：US06626852B2
公开(公告)日：2003-09-30
申请号：US09862360
申请日：2001-05-22
申请人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
发明人： David A. White , William M. Belef , Lawrence Wasicek , Ronald J. Jabba
IPC分类号： A61B814
CPC分类号： A61B8/12 , A61B8/4461 , A61M25/00 , A61M39/10
摘要： An improved catheter system having an ultrasonic imaging transducer coupled to a drive cable disposed within a lumen of a flexible tubular catheter body. An improvement including a reconfiguration of the ferrites in the hub assembly, such that the need for the gap between the ferrites is removed. A strain relief member is provided to increase the strength of the electrical transmission lines to enable them to withstand the tensile forces caused by either flushing and/or pull-back operations. A device which allows the electrical transmission lines to extend their length when placed in tension may also be employed to provide strain relief to the electrical transmission lines. Another improvement includes a counter-wound coil structure, which may either expand or contract as the drive cable is being rotated to strengthen the drive cable. The distal tip of the catheter body may be redesigned to provide a lumen which allows for the release of flushing fluids through a distal port in the guidewire lumen.

48. 发明申请

US20110218567A1 Systems and Methods for Treating Septal Defects 审中-公开
标题翻译：系统和方法治疗间隔缺损
公开(公告)号：US20110218567A1
公开(公告)日：2011-09-08
申请号：US13111885
申请日：2011-05-19
申请人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
发明人： Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Richard S. Ginn , Ronald J. Jabba , William A. Gray
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要： A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译：提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。可植入治疗装置优选通过中隔壁或其部分植入。治疗系统可以包括柔性细长主体构件，配置成输送可植入装置的输送装置，被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。

49. 发明授权

US07846179B2 Suture-based systems and methods for treating septal defects 失效
标题翻译：基于缝合的系统和治疗间隔缺损的方法
公开(公告)号：US07846179B2
公开(公告)日：2010-12-07
申请号：US11218794
申请日：2005-09-01
申请人： W. Martin Belef , Dean Carson , Richard S. Ginn , Ronald J. Jabba
发明人： W. Martin Belef , Dean Carson , Richard S. Ginn , Ronald J. Jabba
IPC分类号： A61B17/06
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B2017/00575 , A61B2017/0404 , A61B2017/0406 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0448 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0462 , A61B2017/0464 , A61B2017/047 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052
摘要： A system for treating a septal defect having a suture-like implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The suture-like apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the suture-like apparatus, a stabilization device configured to stabilize the delivery device and a positioning device configured to position the delivery device in a desired location. The suture-like device can include a suture body coupled with one or more lock devices or anchor devices.
摘要翻译：提供了一种用于治疗具有缝合线可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。缝线状装置优选通过隔壁或其部分植入。处理系统可以包括柔性细长主体构件，配置成输送缝合线状装置的输送装置，被配置为稳定输送装置的稳定装置和被配置成将输送装置定位在期望位置的定位装置。缝合线状装置可以包括与一个或多个锁定装置或锚定装置连接的缝线体。

50. 发明授权

US06749621B2 Sheath apparatus and methods for delivering a closure device 有权
公开(公告)号：US06749621B2
公开(公告)日：2004-06-15
申请号：US10081725
申请日：2002-02-21
申请人： Anthony Pantages , Ronald J. Jabba , Richard S. Ginn
发明人： Anthony Pantages , Ronald J. Jabba , Richard S. Ginn
IPC分类号： A61B1704
CPC分类号： A61B17/0057 , A61B17/064 , A61B17/08 , A61B2017/00004 , A61B2017/00637 , A61B2017/00659 , A61B2017/00668 , A61B2017/00672 , A61B2017/0641
摘要： An apparatus for delivering a clip includes an introducer sheath including an outer surface extending between its proximal and distal ends. A clip is carried on the outer surface, e.g., on a carrier assembly that is slidable along the outer surface from the proximal end towards the distal end. A skin overlies the outer surface of the sheath and the carrier assembly that is separable from the outer surface as the carrier assembly is advanced from the proximal end towards the distal end of the sheath. During use, the distal end of the sheath is inserted into an opening through tissue, e.g., into a puncture communicating with a blood vessel. The carrier assembly is advanced towards the distal end of the sheath, causing the skin to separate from the outer surface of the elongate member, and the clip is deployed from the carrier to seal the opening.

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