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41. 发明申请

US20050271302A1 GPU-based image manipulation method for registration applications 有权
标题翻译：基于GPU的图像处理方法用于注册应用
公开(公告)号：US20050271302A1
公开(公告)日：2005-12-08
申请号：US11109126
申请日：2005-04-19
申请人： Ali Khamene , Christophe Chefd'hotel , Jens Guhring , Bernhard Geiger , Sebastian Vogt
发明人： Ali Khamene , Christophe Chefd'hotel , Jens Guhring , Bernhard Geiger , Sebastian Vogt
IPC分类号： G06K9/00 , G06K9/64 , G06T7/00
CPC分类号： G06T15/005 , G06K9/00986 , G06K9/64 , G06T1/20 , G06T7/35 , G06T2200/28 , G06T2207/10072 , G06T2207/10116 , G06T2207/10132 , G06T2207/30004
摘要： Exemplary systems and methods for performing registration applications are provided. An exemplary system includes a central processing unit (CPU) for transferring a plurality of images to a graphics processing unit (GPU); wherein the GPU performs a registration application on the plurality of images to produce a registration result, and wherein the GPU returns the registration result to the CPU. An exemplary method includes the steps of transferring a plurality of images from a central processing unit (CPU) to a graphics processing unit (GPU); performing a registration application on the plurality of images using the GPU; transferring the result of the step of performing from the GPU to CPU.
摘要翻译：提供了用于执行注册申请的示例性系统和方法。示例性系统包括用于将多个图像传送到图形处理单元（GPU）的中央处理单元（CPU）; 其中所述GPU对所述多个图像执行注册应用以产生注册结果，并且其中所述GPU将所述注册结果返回给所述CPU。一种示例性方法包括将多个图像从中央处理单元（CPU）传送到图形处理单元（GPU）的步骤; 使用所述GPU对所述多个图像执行注册应用; 将执行步骤的结果从GPU传送到CPU。

42. 发明申请

US20050238223A1 Flexible generation of digitally reconstructed radiographs 有权
标题翻译：灵活地生成数字重建的X光片
公开(公告)号：US20050238223A1
公开(公告)日：2005-10-27
申请号：US10953342
申请日：2004-09-29
申请人： Jens Guhring , Sebastian Vogt , Ali Khamene
发明人： Jens Guhring , Sebastian Vogt , Ali Khamene
IPC分类号： G06K9/00 , G06K9/36 , G06T15/08
CPC分类号： G06T15/08
摘要： A system and corresponding method for flexible generation of digitally reconstructed radiograph (DRR) images on a graphics processing unit (GPU) are provided, the system including a processor, an imaging adapter in signal communication with the processor for receiving volumetric data, an integration unit in signal communication with the processor for integrating the volumetric data into incremental line integrals, and a modeling unit in signal communication with the processor for modeling composite line integrals from the incremental line integrals; and the corresponding method including receiving three-dimensional (3D) volumetric data into a graphics pipeline, integrating the 3D volumetric data into incremental line integrals along a plurality of viewing rays, modeling composite line integrals from the incremental line integrals, and adding the incremental line integrals for each composite line integral to form pixels of the DRR image.
摘要翻译：提供了一种用于在图形处理单元（GPU）上灵活生成数字重建X射线照片（DRR）图像的系统和相应方法，该系统包括处理器，与处理器进行信号通信的成像适配器，用于接收体积数据，整合单元与处理器的信号通信，用于将体积数据集成到增量线积分中，以及与处理器进行信号通信的建模单元，用于从增量线积分建模复合线积分; 以及相应的方法，包括将三维（3D）体积数据接收到图形管线中，将3D体积数据集成到沿着多个观察射线的增量线积分中，从增量线积分建模复合线积分，以及将增量线每个复合线的积分积分以形成DRR图像的像素。

43. 发明授权

US06913764B2 Antibiotic(s) preparation with retarding active ingredient release 失效
标题翻译：具有延缓活性成分释放的抗生素制剂
公开(公告)号：US06913764B2
公开(公告)日：2005-07-05
申请号：US10100839
申请日：2002-03-19
申请人： Sebastian Vogt , Matthias Schnabelrauch , Klaus-Dieter Kühn
发明人： Sebastian Vogt , Matthias Schnabelrauch , Klaus-Dieter Kühn
IPC分类号： A61K9/00 , A61K9/10 , A61K9/14 , A61K9/20 , A61K9/22 , A61K9/70 , A61K31/00 , A61K31/70 , A61K31/7036 , A61K31/726 , A61K45/06 , A61K45/08 , A61K47/02 , A61K47/14 , A61K47/16 , A61K47/20 , A61K47/24 , A61L27/54 , A61L31/16 , A61K2/02
CPC分类号： A61K31/7036 , A61K9/0024 , A61K9/2013 , A61K31/00 , A61L27/54 , A61L2300/406 , A61L2300/602 , A61L2300/802
摘要： The present invention concerns an antibiotic/antibiotics preparation for resorbable and non-resorbable implants for human and veterinary medicine, for the treatment of local microbial infections in hard and soft tissue. The invented antibiotic/antibiotics preparation is a mixture consisting of at least one amphiphilic component of a representative of the alkyl sulfates, aryl sulfates, alkylaryl sulfates, cycloalkyl sulfates, alkylcycloalkyl sulfates, alkyl sulfamates, cycloalkyl sulfamates, alkylcycloalkyl sulfamates, aryl sulfamates, alkylaryl sulfamates, alkyl sulfonates, fatty acid-2-sulfonates, aryl sulfonates, alkylaryl sulfonates, cycloalkyl sulfonates, alkylcycloalkyl sulfonates, alkyl disulfates, cycloalkyl disulfates, alkyl disulfonates, cycloalkyl disulfonates, aryl disulfonates, alkylaryl disulfonates, aryl trisulfonates and alkylaryl trisulfonates as well as at least one antibiotic component from the group of aminoglycoside antibiotics, lincosamide antibiotics, 4-quinolone antibiotics and tetracycline antibiotics, and if need be at least one anhydrous organic auxiliary component and if need be at least one inorganic auxiliary component and if need be at least one biologically active component. The antibiotic/antibiotics preparation of the invention has a retarding active ingredient release.
摘要翻译：本发明涉及用于人和兽医药物的可再吸收和不可吸收植入物的抗生素/抗生素制剂，用于治疗硬组织和软组织中的局部微生物感染。本发明的抗生素/抗生素制剂是由至少一种代表烷基硫酸盐，芳基硫酸盐，烷基芳基硫酸盐，环烷基硫酸盐，烷基环烷基硫酸盐，氨基磺酸烷基酯，环烷基磺酸盐，烷基环烷基氨基磺酸盐，芳基亚磺酸盐，烷基芳基亚磺酸盐烷基磺酸盐，脂肪酸-2-磺酸盐，芳基磺酸盐，烷基芳基磺酸盐，环烷基磺酸盐，烷基环烷基磺酸盐，烷基二硫酸盐，环烷基二硫酸盐，烷基二磺酸盐，环烷基二磺酸盐，芳基二磺酸盐，烷基芳基二磺酸盐，芳基三磺酸盐和烷基芳基三磺酸盐以及至少一种来自氨基糖苷类抗生素的抗生素成分，林可素类抗生素，4-喹诺酮类抗生素和四环素抗生素，如果需要至少一种无机有机辅助成分，如果需要至少一种无机辅助成分，如果需要至少一种生物活性成分 ent。本发明的抗生素/抗生素制剂具有缓释活性成分释放。

44. 发明授权

US06702082B2 Leaf spring arrangement, especially for attaching the pressure plate of a pressure plate assembly to a housing 失效
标题翻译：叶片弹簧装置，特别是用于将压板组件的压板连接到壳体
公开(公告)号：US06702082B2
公开(公告)日：2004-03-09
申请号：US09949686
申请日：2001-09-10
申请人： Matthias Dörfler , Andreas Orlamünder , Andreas Dau , Albert Kammermeier , Hartmut Bach , Cora Carlson , Günther Esly , Reinhard Feldhaus , Ingrid Hoffelner , Christoph Kleuker , Paul Kraus , Bernd Peinemann , Michael Peterseim , Gerhard R{overscore (o)}ll , Ralf Till , Sebastian Vogt
发明人： Matthias Dörfler , Andreas Orlamünder , Andreas Dau , Albert Kammermeier , Hartmut Bach , Cora Carlson , Günther Esly , Reinhard Feldhaus , Ingrid Hoffelner , Christoph Kleuker , Paul Kraus , Bernd Peinemann , Michael Peterseim , Gerhard R{overscore (o)}ll , Ralf Till , Sebastian Vogt
IPC分类号： F16D1318
CPC分类号： F16D13/71 , F16D2013/706 , Y10T403/45
摘要： A leaf spring arrangement, especially for connecting a pressure plate to a housing, comprises a plurality of adjacent leaf spring elements, where each leaf spring element has a first attachment area for establishing the connection the pressure plate, a second attachment area for establishing the connection to the housing, and a connecting area extending between the first attachment area and the second attachment area. At least certain areas of at least two of the leaf spring elements are spaced apart between their first attachment area and their second attachment area.
摘要翻译：特别是用于将压板连接到壳体的板簧装置包括多个相邻的板簧元件，其中每个板簧元件具有用于建立压板的连接的第一附接区域，用于建立连接的第二附接区域以及在所述第一附接区域和所述第二附接区域之间延伸的连接区域。至少两个板簧元件的至少一些区域在它们的第一附接区域和它们的第二附接区域之间间隔开。

45. 发明授权

US09289267B2 Method and apparatus for minimally invasive surgery using endoscopes 有权
标题翻译：使用内窥镜进行微创手术的方法和装置
公开(公告)号：US09289267B2
公开(公告)日：2016-03-22
申请号：US11383598
申请日：2006-05-16
申请人： Frank Sauer , Ali Khamene , Sebastian Vogt
发明人： Frank Sauer , Ali Khamene , Sebastian Vogt
IPC分类号： A61B1/00 , A61B1/04 , A62B1/04 , A61B19/00 , G06F19/00
CPC分类号： A61B34/20 , A61B1/0005 , A61B1/04 , A61B90/36 , A61B2090/364 , A61B2090/376 , G16H50/50
摘要： A method and apparatus for presenting three-dimensional data to a physician is provided to facilitate the flexible navigation of an endoscope and surgical instruments with respect to anatomical structures. In accordance with a first embodiment a first set of data corresponding to a three dimensional model of a patient's anatomy is received. This three-dimensional model may be rendered from images taken in CT or MRI scanning, as discussed above. In accordance with this embodiment, this model is then combined with a second set of data corresponding to a view obtained from an endoscope. In another embodiment, the view from the illustrative endoscope is displayed as an inset image on the display of the three-dimensional image. In yet another embodiment, the three-dimensional image comprises a graphical representation of at least a first surgical instrument, such as said endoscope. The surgeon may select among various combinations of views and may zoom in or out from any particular view.
摘要翻译：提供了一种用于向医师呈现三维数据的方法和装置，以便于内窥镜和外科器械相对于解剖结构的灵活导航。根据第一实施例，接收对应于患者解剖结构的三维模型的第一组数据。如上所述，该三维模型可以从在CT或MRI扫描中拍摄的图像呈现。根据本实施例，然后将该模型与对应于从内窥镜获得的视图的第二组数据组合。在另一个实施例中，来自说明性内窥镜的视图作为插入图像被显示在三维图像的显示器上。在另一个实施例中，三维图像包括至少第一外科器械（例如所述内窥镜）的图形表示。外科医生可以在各种视图组合中进行选择，并且可以放大或缩小任何特定视图。

46. 发明申请

US20130231673A1 CARTRIDGE SYSTEM HAVING CONNECTED FEED PLUNGERS 有权
标题翻译：具有连接进料龙头的墨盒系统
公开(公告)号：US20130231673A1
公开(公告)日：2013-09-05
申请号：US13696214
申请日：2011-04-15
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： A61B17/88
CPC分类号： A61B17/8805 , A61C5/64 , B05C17/00506 , B05C17/00513 , B05C17/00553 , B05C17/00576
摘要： Cartridge system for mixing and applying a mix of a medical cement. Cartridges are arranged parallel to each other having and an outlet opening. The cartridges each comprise at least one opening that connect(s) the cartridges to the outlet opening, and the cartridges are bordered laterally through cartridge walls. Each cartridge comprises a feed plunger for expelling starting components of the mix from the cartridges through the openings. The feed plungers are fixedly connected to each other and are fixedly connected to each other through at least one fin. The cartridge walls of the cartridges are connected through the fin(s). The walls comprise slits that are arranged parallel to the cartridge axis, whereby the width of the slits is well-suited for taking up the fin or fins, and the at least one fin moves through regions of the slits when the feed plungers perform a motion in the cartridges.
摘要翻译：用于混合和应用医用水泥混合物的墨盒系统。墨盒彼此平行布置并具有出口开口。每个盒包括将盒连接到出口开口的至少一个开口，并且盒沿横向穿过盒壁。每个墨盒包括用于从墨盒通过开口排出混合物的起始部件的进料柱塞。进料柱塞彼此固定连接并且通过至少一个翅片彼此固定连接。墨盒的墨盒壁通过散热片连接。壁包括平行于盒轴线布置的狭缝，由此狭缝的宽度非常适于吸收翅片或翅片，并且当进给柱塞进行运动时，至少一个翼片移动穿过狭缝的区域在墨盒中。

47. 发明申请

US20130144300A1 APPLICATOR KIT 审中-公开
标题翻译：应用工具包
公开(公告)号：US20130144300A1
公开(公告)日：2013-06-06
申请号：US13553305
申请日：2012-07-19
申请人： Sebastian Vogt , Daniela Villone , Frank Finis , Rüdiger Creuzburg
发明人： Sebastian Vogt , Daniela Villone , Frank Finis , Rüdiger Creuzburg
IPC分类号： A61F2/28
CPC分类号： A61F2/4601 , A61B17/7095 , A61B17/8811 , A61B17/8819 , A61B17/8825
摘要： An applicator and applicator kit for particulate bone replacement materials, autologous or heterologous cancellous bone, demineralised bone matrix. The applicator (1) contains a hollow tube (12) including on one end a bladed shutter. The applicator comprises first fastener (15) for engaging a second component. The second component contains a rod (2) with a handle (21) on one end and a plunger (22) on the opposite end. The rod is arranged in a guide sleeve which is moved along the rod (2) and comprises second fastening means (23) that can be connected to the fastener (15) of the applicator (1) in reversible manner. The applicator kit contains a mixing cup connected to the tube (12) instead of the rod such that the material to be applied is filled into the tube (12) easily prior to application.
摘要翻译：用于颗粒状骨置换材料的自动或异种松质骨，脱钙骨基质的涂抹器和涂抹器套件。施加器（1）包含中空管（12），该中空管（12）的一端包括叶片快门。涂抹器包括用于接合第二部件的第一紧固件（15）。第二部件包括在一端具有手柄（21）的杆（2）和在另一端上的柱塞（22）。杆被布置在沿着杆（2）移动的引导套筒中，并且包括能够以可逆方式连接到施用器（1）的紧固件（15）的第二紧固装置（23）。施用器套件包含连接到管（12）而不是杆的混合杯，使得待施用的材料在施用之前容易地填充到管（12）中。

48. 发明申请

US20120132104A1 DENTAL MATERIALS CONTAINING ANTIMICROBIAL AGENTS, PARTICULARLY FOR THE PREVENTION OF PLAQUE DEPOSITS 审中-公开
标题翻译：含有抗菌剂的牙科材料，特别是防止沉淀物
公开(公告)号：US20120132104A1
公开(公告)日：2012-05-31
申请号：US13382699
申请日：2010-07-24
申请人： Klaus Ruppert , Mario Beyer , Sebastian Vogt
发明人： Klaus Ruppert , Mario Beyer , Sebastian Vogt
IPC分类号： A61K6/00 , C07D401/06 , C08F220/14 , A61K6/083 , C08F236/20
CPC分类号： A61K6/0088 , A61K6/0017 , A61K6/0023 , A61K6/0067 , A61K6/0091 , A61K6/024 , A61K6/083 , A61K6/10 , C08L33/10
摘要： Dental material is provided with at least one antimicrobial active substance that is applied onto inorganic particles or organic polymer beads and is bound non-covalently to the particles or polymer beads.This results in a dental material on which plaque colonisation is prevented.
摘要翻译：牙科材料设置有至少一种抗微生物活性物质，其被施加到无机颗粒或有机聚合物珠粒上并与颗粒或聚合物珠粒非共价结合。这导致防止斑块定植的牙科材料。

49. 发明申请

US20110112210A1 PMMA PASTE 审中-公开
公开(公告)号：US20110112210A1
公开(公告)日：2011-05-12
申请号：US13001890
申请日：2009-06-13
申请人： Sebastian Vogt , Hubert Buechner
发明人： Sebastian Vogt , Hubert Buechner
IPC分类号： A61L24/06
CPC分类号： A61L24/0015 , A61L24/06 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/43 , A61L2430/02 , C08L33/12
摘要： A PMMA paste is made from a mixture of (A) methyl methacrylate having a methacrylic acid content of less than 1% and a water content of less than 1% and (B) at least one polymethyl methacrylate having a Tg of more than 65° C. and a molar mass of greater than or equal to 200,000 g/mol. The methyl methacrylate fraction is sufficient for the PMMA paste to be autosterile, the weight ratio of (B) to (A) preferably being 10-50% (B) to 50-90% (A). The PMMA paste can be used to produce paste-like one-component bone cements and two-component bone cements.
摘要翻译： PMMA糊料由（A）甲基丙烯酸含量小于1％，水含量小于1％的（甲基）甲基丙烯酸酯的混合物制成，（B）至少一种Tg高于65°的聚甲基丙烯酸甲酯并且摩尔质量大于或等于200,000g / mol。甲基丙烯酸甲酯部分足以使PMMA糊状物成为无菌，（B）与（A）的重量比优选为10-50％（B）至50-90％（A）。 PMMA糊剂可用于生产糊状单组分骨水泥和双组分骨水泥。

50. 发明授权

US07923019B2 Antibiotic/s containing bone substitute material with sustained active substance release 有权
标题翻译：含有持久活性物质释放的骨替代材料的抗生素
公开(公告)号：US07923019B2
公开(公告)日：2011-04-12
申请号：US11294001
申请日：2005-12-05
申请人： Klaus-Dieter Kühn , Sebastian Vogt
发明人： Klaus-Dieter Kühn , Sebastian Vogt
IPC分类号： A61K33/42 , A61F2/00
CPC分类号： A61L27/025 , A61L27/54 , A61L2300/404 , A61L2300/406 , A61L2430/02
摘要： Antibiotic/s containing bone substitute material is described which is characterized in that it is composed of a compacted mixture of granules of calcium sulfate dihydrate, calcium carbonate and at least one representative of the aminoglycoside antibiotics, lincosamide antibiotics, glycopeptide antibiotics, macrolide antibiotics, ketolide antibiotics, the nitroimidazoles, the fluorochinolone antibiotics and the oxazolidinone antibiotics, the steroid antibiotics, the antiseptic agents and the fungicidal/fungistatic antibiotics which are partly or entirely sheathed with a layer of glycerol tripalmitate and/or glycerol tristearate and/or glycerol trilaurate and/or 1-hexadecyl alcohol which connects the granules with each other.
摘要翻译：描述了含有抗生素的骨替代材料，其特征在于其由硫酸钙二水合物，碳酸钙和至少一种氨基糖苷类抗生素代谢物的压实混合物，氯胺素抗生素，糖肽抗生素，大环内酯类抗生素，酮内酯抗生素，硝基咪唑，氟喹诺酮抗生素和恶唑烷酮抗生素，类固醇抗生素，防腐剂和杀真菌/抑菌抗生素，其部分或全部用三层棕榈酸甘油酯和/或甘油三硬脂酸酯和/或甘油三月桂酸酯和/ 或将该颗粒彼此连接的1-十六烷基醇。

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