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41. 发明授权

US06868291B1 Arrangement for implanting an endocardial cardiac lead 有权
标题翻译：用于植入心内膜心脏铅的装置
公开(公告)号：US06868291B1
公开(公告)日：2005-03-15
申请号：US09699865
申请日：2000-10-30
申请人： Matthew D. Bonner , Timothy G. Laske
发明人： Matthew D. Bonner , Timothy G. Laske
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61M25/0043 , A61M25/01 , A61N2001/0578
摘要： An arrangement for introducing and implanting the electrode(s) of an endocardial implantable cardiac lead at a cardiac implantation site within a heart chamber or vessel. An elongated guide body formed of flexible material and extending between a guide body proximal end and a guide body distal end is advanced transvenously to position the guide body distal end in relation to the cardiac implantation site. Guide body tracking means is coupled with the lead distal end for receiving and slidingly engaging the guide body to allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. Pusher means formed of an elongated pusher body of flexible material extends between a pusher body proximal end and a pusher body distal end and has a cardiac lead engaging means for engaging the cardiac lead at or adjacent the distal lead end. The pusher body has sufficient column strength to be advanced alongside the guide body and lead body with the cardiac lead engaging means engaging and slidingly advancing the guide body tracking means and the cardiac lead distally along the guide body to thereby allow the cardiac lead to be advanced along the guide body until the electrode is positioned at the cardiac implantation site. The lead body is released from the lead engaging means and fixed, if the lead includes a fixation mechanism. The pusher means is retracted by retraction of the pusher body.
摘要翻译：用于在心室或血管内的心脏植入部位处引入和植入心内可植入心脏引线的电极的装置。由柔性材料形成并在引导体近端和引导体远端之间延伸的细长引导体相对于心脏植入部位传递推进以引导体远端。引导体跟踪装置与引线远端联接，用于接收和滑动地接合引导体，以允许心脏引导沿引导体前进，直到电极定位在心脏植入部位。由细长的柔性材料推动器构成的推动器装置在推动器本体近端和推动器主体远端之间延伸，并且具有心脏引线接合装置，用于在远侧引线端处或与其相邻的心脏引线接合。推动器主体具有足够的柱强度，以使引导体和引线体沿着引导体接合装置前进，引导体跟踪装置和心引导件沿引导体向远侧滑动，从而允许心导线前进沿着引导体直到电极位于心脏植入部位。如果引线包括固定机构，则引线体从引线接合装置释放并固定。推动器装置通过推动器主体的缩回缩回。

42. 发明授权

US06021354A Single pass lead and method of use 有权
标题翻译：单通铅和使用方法
公开(公告)号：US06021354A
公开(公告)日：2000-02-01
申请号：US224739
申请日：1998-12-31
申请人： Eduardo N. Warman , Matthew D. Bonner
发明人： Eduardo N. Warman , Matthew D. Bonner
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： A cardiac pacing lead for pacing the atria and a method of its use. The lead is provided with a mechanism for maintaining an atrial pacing electrode adjacent stimulable tissue in a patient's superior vena cava and an additional electrode locatable in the right ventricle or elsewhere when the atrial electrode is so located. One such mechanism for maintaining the atrial electrode's position may be a lead body displaying pre-formed laterally extending curves sized to span a patient's superior vena cava, with the atrial electrode located thereon.
摘要翻译：用于起搏心房的心脏起搏线及其使用方法。该引线设置有用于将心房起搏电极维持在患者上腔静脉中的可刺激组织旁边的机构，以及当心房电极如此定位时位于右心室或别处的附加电极。用于维持心房电极的位置的一种这样的机构可以是引导体，其显示预先形成的横向延伸的曲线，其尺寸跨越患者的上腔静脉，心房电极位于其上。

43. 发明授权

US5968086A Pacing and cardioversion lead systems with shared lead conductors 失效
标题翻译：起搏和心脏复律引导系统具有共用引线导体
公开(公告)号：US5968086A
公开(公告)日：1999-10-19
申请号：US28143
申请日：1998-02-23
申请人： Matthew D. Bonner , Adrianus P. Donders
发明人： Matthew D. Bonner , Adrianus P. Donders
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0563
摘要： An implantable electrical lead having an elongated insulative lead body carrying a cardioversion/defibrillation electrode and a sensing electrode spaced from the cardioversion/defibrillation electrode. A diode enclosure is mounted in the lead body between the cardioversion/defibrillation electrode and the sensing electrode, the diode enclosure having conductive end walls and including a diode or diodes therein coupled between the conductive end walls. The enclosure is also provided with a feedthrough tube extending through said enclosure, passing through the end walls. An elongated conductor extends through the lead body and through the feedthrough tube of said enclosure and is electrically coupled to the sensing electrode. The cardioversion/defibrillation electrode and the sensing electrode are each electrically coupled to one of the conductive end walls of the diode enclosure.
摘要翻译：一种可植入电引线，其具有承载心脏复律/除颤电极的细长绝缘引线体和与心脏复律/除颤电极间隔开的感测电极。二极管外壳安装在心脏复律电极和感测电极之间的引线主体中，二极管外壳具有导电端壁并且包括耦合在导电端壁之间的二极管或二极管。外壳还设置有穿过所述外壳延伸穿过端壁的馈通管。细长的导体延伸穿过引线主体并穿过所述外壳的馈通管并且电耦合到感测电极。心脏复律/除颤电极和感测电极各自电耦合到二极管外壳的导电端壁之一。

44. 发明授权

US09775982B2 Implantable medical device fixation 有权
公开(公告)号：US09775982B2
公开(公告)日：2017-10-03
申请号：US13096881
申请日：2011-04-28
申请人： Vladimir Grubac , Matthew D. Bonner , Raymond W. Usher , Thomas A. Anderson , Arshad A. Alfoqaha
发明人： Vladimir Grubac , Matthew D. Bonner , Raymond W. Usher , Thomas A. Anderson , Arshad A. Alfoqaha
IPC分类号： A61N1/05 , A61N1/375
CPC分类号： A61N1/05 , A61N1/0573 , A61N1/37518 , A61N1/3756
摘要： Various fixation techniques for implantable medical device (IMDs) are described. In one example, an assembly comprises an IMD; and a set of active fixation tines attached to the IMD. The active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the IMD to a hooked position in which the active fixation tines bend back towards the IMD. The active fixation tines are configured to secure the IMD to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue.

45. 发明申请

US20150045868A1 IMPLANTABLE MEDICAL DEVICE FIXATION 审中-公开
标题翻译：可植入医疗器械固定
公开(公告)号：US20150045868A1
公开(公告)日：2015-02-12
申请号：US13959808
申请日：2013-08-06
申请人： Matthew D. Bonner , Thomas A. Anderson , William A. Berthiaume , Noelle C. Hurtig
发明人： Matthew D. Bonner , Thomas A. Anderson , William A. Berthiaume , Noelle C. Hurtig
IPC分类号： A61N1/375 , A61N1/362
CPC分类号： A61N1/3756 , A61N1/0573 , A61N1/362 , A61N1/37205 , A61N1/37518
摘要： Various fixation techniques for implantable medical device (IMDs) are described. In one example, an assembly comprises an IMD; and a set of active fixation tines attached to the IMD. The active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the IMD to a hooked position in which the active fixation tines bend back towards the IMD. The active fixation tines are configured to secure the IMD to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue.
摘要翻译：描述了用于可植入医疗装置（IMD）的各种固定技术。在一个示例中，组件包括IMD; 以及一组附加在IMD上的活动固定齿。组合中的主动固定齿可从弹簧加载位置展开，其中活动固定尖端的远端指向远离IMD的钩状位置，其中主动固定齿向IMD向后弯曲。活动的固定齿构造成当展开时将IMD固定到患者组织，同时主动固定齿的远端定位成与患者组织相邻。

46. 发明申请

US20120172892A1 IMPLANTABLE MEDICAL DEVICE FIXATION 有权
标题翻译：可植入医疗器械固定
公开(公告)号：US20120172892A1
公开(公告)日：2012-07-05
申请号：US13096881
申请日：2011-04-28
申请人： Vladimir Grubac , Matthew D. Bonner , Raymond W. Usher , Thomas A. Anderson , Arshad A. Alfoqaha
发明人： Vladimir Grubac , Matthew D. Bonner , Raymond W. Usher , Thomas A. Anderson , Arshad A. Alfoqaha
IPC分类号： A61N1/05 , A61B19/00
CPC分类号： A61N1/05 , A61N1/0573 , A61N1/37518 , A61N1/3756
摘要： Various fixation techniques for implantable medical device (IMDs) are described. In one example, an assembly comprises an IMD; and a set of active fixation tines attached to the IMD. The active fixation tines in the set are deployable from a spring-loaded position in which distal ends of the active fixation tines point away from the IMD to a hooked position in which the active fixation tines bend back towards the IMD. The active fixation tines are configured to secure the IMD to a patient tissue when deployed while the distal ends of the active fixation tines are positioned adjacent to the patient tissue.
摘要翻译：描述了用于可植入医疗装置（IMD）的各种固定技术。在一个示例中，组件包括IMD; 以及一组附加在IMD上的活动固定齿。组合中的主动固定齿可从弹簧加载位置展开，其中活动固定尖端的远端指向远离IMD的钩状位置，其中主动固定齿向IMD向后弯曲。活动的固定齿构造成当展开时将IMD固定到患者组织，同时主动固定齿的远端定位成与患者组织相邻。

47. 发明申请

US20120109148A1 SYSTEM AND METHOD FOR RETRIEVAL OF AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于检索可植入医疗器械的系统和方法
公开(公告)号：US20120109148A1
公开(公告)日：2012-05-03
申请号：US12915745
申请日：2010-10-29
申请人： Matthew D. Bonner , Raymond W. Usher
发明人： Matthew D. Bonner , Raymond W. Usher
IPC分类号： A61B17/00
CPC分类号： A61N1/372 , A61N1/3756 , A61N2001/0578
摘要： System and method for extracting an implantable medical device. An implantable medical device has a fixation member operatively coupled to the housing having an engaged state configured to engage tissue of a patient, the medical device being magnetically attractable. A catheter has a lumen and a distal portion configured for insertion in proximity of the implantable medical device. A magnetic element is configured to pass through the lumen of the catheter and to magnetically engage the implantable medical device when inserted toward the distal portion of the catheter.
摘要翻译：用于提取可植入医疗装置的系统和方法。可植入医疗装置具有可操作地联接到壳体的固定构件，其具有被配置为接合患者的组织的接合状态，该医疗装置是磁吸引的。导管具有被配置为插入在可植入医疗装置附近的内腔和远侧部分。磁性元件构造成穿过导管的内腔，并且当插入到导管的远端部分时磁性地接合可植入医疗装置。

48. 发明申请

US20090276025A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 有权
公开(公告)号：US20090276025A1
公开(公告)日：2009-11-05
申请号：US12433768
申请日：2009-04-30
申请人： John E. Burnes , Mary M. Morris , Michael R.S. Hill , Avram Scheiner , Ruth N. Klepfer , Matthew D. Bonner
发明人： John E. Burnes , Mary M. Morris , Michael R.S. Hill , Avram Scheiner , Ruth N. Klepfer , Matthew D. Bonner
IPC分类号： A61N1/05
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient.

49. 发明授权

US07191016B2 Medical system including a novel bipolar pacing and sensing pair 失效
标题翻译：包括新型双极起搏和感应对的医疗系统
公开(公告)号：US07191016B2
公开(公告)日：2007-03-13
申请号：US10439201
申请日：2003-05-15
申请人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
发明人： Mark T. Marshall , Teresa A. Whitman , Eduardo N. Warman , Jeffrey M. Gillberg , Matthew D. Bonner , Mark L. Brown
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , A61N1/0568 , A61N1/057 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： A medical electrical lead includes a first low voltage electrode adapted for intimate contact with tissue at an implant site, in order to provide pacing stimulation, and a second low voltage electrode positioned in proximity to the first electrode, isolated from the first electrode and adapted to function in conjunction with the first electrode to provide bipolar sensing of near-field signals. A porous layer is formed over the second electrode; the porous layer allows conduction therethrough while preventing contact between the second electrode and tissue in proximity to the implant site.
摘要翻译：医疗电引线包括适于在植入部位处与组织紧密接触的第一低电压电极，以便提供起搏刺激，以及位于第一电极附近的第二低电压电极，与第一电极隔离并且适于与第一电极结合起来提供近场信号的双极感测。在第二电极上形成多孔层; 多孔层允许穿过其中，同时防止在植入部位附近的第二电极和组织之间的接触。

50. 发明授权

US09504820B2 System and method for implantation of an implantable medical device 有权
标题翻译：用于植入可植入医疗装置的系统和方法
公开(公告)号：US09504820B2
公开(公告)日：2016-11-29
申请号：US12915859
申请日：2010-10-29
申请人： Matthew D. Bonner , Raymond W. Usher
发明人： Matthew D. Bonner , Raymond W. Usher
IPC分类号： A61B19/00 , A61N1/05 , A61N1/372 , A61N1/375
CPC分类号： A61N1/057 , A61N1/372 , A61N1/37205 , A61N1/3756 , A61N2001/0578 , A61N2001/058
摘要： System and method for implanting an implantable medical device. A catheter has a lumen and a distal portion configured for insertion in proximity of tissue of a patient. An implantable medical device has a fixation member operatively coupled to the housing having an unengaged state when in the lumen of the catheter and an engaged state configured to engage tissue of a patient when outside of the lumen of the catheter, the medical device being magnetically attractable. A magnetic element is configured to magnetically engage the implantable medical device and to pass through the lumen of the catheter.
摘要翻译：用于植入可植入医疗装置的系统和方法。导管具有被配置用于插入患者组织附近的内腔和远端部分。可植入医疗装置具有可操作地联接到壳体的固定构件，其在导管的内腔中具有未接合状态，并且被配置为在导管内腔外部接合患者的组织的接合状态，医疗装置是磁性吸引的。磁性元件构造成磁性接合可植入医疗装置并穿过导管的内腔。

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