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41. 发明授权

US06656174B1 Devices and methods for creating lesions in blood vessels without obstructing blood flow 有权
标题翻译：消融导管与径向设置的可充气室
公开(公告)号：US06656174B1
公开(公告)日：2003-12-02
申请号：US09619857
申请日：2000-07-20
申请人： Anant V. Hegde , Steven L. Olson , David K. Swanson
发明人： Anant V. Hegde , Steven L. Olson , David K. Swanson
IPC分类号： A61B1808
CPC分类号： A61B18/1492 , A61B2018/00065 , A61B2018/0022 , A61B2018/00238 , A61B2018/00375
摘要： An ablation catheter that includes radially disposed inflatable chambers is provided. The ablation catheter includes an elongate catheter body and an electrode structure mounted on the distal end of the catheter body. The electrode structure includes a plurality of radially disposed inflatable chambers. The elongate catheter body may be composed of an inner shaft having an inner shaft lumen, a stiffening mandrel disposed within the inner shaft lumen, and an outer shaft having an outer shaft lumen, wherein the inner shaft is disposed within the outer shaft lumen. The outer shaft includes a plurality of inflation lumens in communication with the interior regions of the inflatable chambers, which deliver an inflation medium to the inflatable chambers. The inner shaft includes a plurality of lumens that house electrical leads for delivering ablation energy to the electrode structure.
摘要翻译：提供包括径向设置的可充气室的消融导管。消融导管包括细长的导管主体和安装在导管主体的远端上的电极结构。电极结构包括多个径向设置的可充气室。细长导管主体可以由具有内轴内腔，设置在内轴腔内的加强心轴和具有外轴腔的外轴的内轴组成，其中内轴设置在外轴内腔内。外轴包括与充气室的内部区域连通的多个充气腔，其将充气介质输送到可充气室。内轴包括多个腔，其容纳用于将消融能量传递到电极结构的电引线。

42. 发明授权

US06620159B2 Conductive expandable electrode body and method of manufacturing the same 有权
公开(公告)号：US06620159B2
公开(公告)日：2003-09-16
申请号：US09876009
申请日：2001-06-06
申请人： Anant V. Hegde
发明人： Anant V. Hegde
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/00148 , A61B2018/00214 , A61B2018/0022 , A61B2018/1467
摘要： A balloon body of an electrode assembly includes an elastomeric non-conductive body expandable to a wide variety of working diameters to accommodate a wide variety of anatomical structures. The elastomeric non-conductive body has a circumferential region and an interior adapted to receive an electrically conductive fluid medium for expanding the elastomeric non-conductive body and transmitting electrical current therethough. A plurality of holes are located in the circumferential region of the elastomeric non-conductive body and a conductive elastomeric material covers the holes and forms one or more conductive regions adapted to transmit electrical current received from the electrically conductive fluid medium through the plurality of holes to adjacent body tissue.

43. 发明授权

US06454766B1 Microporous electrode structure and method of making the same 有权
标题翻译：微孔电极结构及其制作方法
公开(公告)号：US06454766B1
公开(公告)日：2002-09-24
申请号：US09565710
申请日：2000-05-05
申请人： David K. Swanson , Huy D. Phan , Anant V. Hegde
发明人： David K. Swanson , Huy D. Phan , Anant V. Hegde
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/00065 , A61B2018/00214 , A61B2018/00238 , A61B2018/1472
摘要： An electrode assembly adapted to transmit electrical energy for ablating body tissue includes an expandable and collapsible non-compliant body made of a durable material and defining an interior adapted to receive a medium containing ions. The body includes a porous region, an electrode adapted to transmit electrical energy located in the interior of the body, a microporous membrane located on the porous region of the non-compliant body, and the microporous membrane is sized to pass ions contained in the medium without substantial medium perfusion therethrough, to thereby enable ionic transport of electrical energy from the ion-containing medium to the exterior of the electrode assembly to ablate body tissue.
摘要翻译：适于传递用于烧蚀身体组织的电能的电极组件包括由耐用材料制成并且限定适于接收含有离子的介质的内部的可膨胀和可折叠的非柔顺体。主体包括多孔区域，适于透射位于身体内部的电能的电极，位于非顺应性体的多孔区域上的微多孔膜，并且该微多孔膜的尺寸设定成使包含在介质中的离子无需通过其进行实质的介质灌注，从而使电能从电离离子的介质到电极组件的外部离子转运以烧蚀身体组织。

44. 发明授权

US6156053A Dual catheter assembly 失效
标题翻译：双导管组装
公开(公告)号：US6156053A
公开(公告)日：2000-12-05
申请号：US71018
申请日：1998-05-01
申请人： Deepak R. Gandhi , Cecily M. Hillsman , Anant V. Hegde , Harm TenHoff
发明人： Deepak R. Gandhi , Cecily M. Hillsman , Anant V. Hegde , Harm TenHoff
IPC分类号： A61F2/82 , A61M25/09 , A61M29/00
CPC分类号： A61M25/1011 , A61F2/958 , A61F2002/826
摘要： The present invention relates to a combination device comprising two catheters, or a dual catheter assembly, for use in vascular procedures wherein the shaft of the first catheter functions as a guidewire for the second catheter. The dual catheter assembly comprises a first balloon catheter and a second balloon catheter wherein the second balloon catheter is slidably disposed on the shaft of the first balloon. In preferred embodiments, the first catheter is a low profile balloon on a wire catheter and the second catheter is a full size balloon catheter having a plurality of balloons mounted thereon. Optionally, a stent is carried by at least one of the balloons on the second catheter. In more preferred embodiments, the second catheter includes a manifold that may be used to inflate and deflate any combination of the plurality of balloons via a single port. The dual catheter assembly of the present invention is especially useful in vascular procedures such as angioplasty, progressive/multiple angioplasty, and stent delivery.
摘要翻译：本发明涉及一种组合装置，其包括用于血管程序的两个导管或双重导管组件，其中第一导管的轴用作第二导管的导丝。双重导管组件包括第一气囊导管和第二气囊导管，其中第二球囊导管可滑动地设置在第一气囊的轴上。在优选实施例中，第一导管是导线导管上的低轮廓气囊，并且第二导管是其上安装有多个气囊的全尺寸球囊导管。任选地，支架由第二导管上的气囊中的至少一个承载。在更优选的实施例中，第二导管包括可用于经由单个端口对多个气囊的任何组合进行充气和放气的歧管。本发明的双导管组件在诸如血管成形术，进行性/多重血管成形术和支架递送的血管手术中特别有用。

45. 发明授权

US08857439B2 Variable automated tissue retention system 有权
标题翻译：可变自动组织保留系统
公开(公告)号：US08857439B2
公开(公告)日：2014-10-14
申请号：US12831913
申请日：2010-07-07
申请人： Anant V. Hegde , Kasey Kai-Chi Li
发明人： Anant V. Hegde , Kasey Kai-Chi Li
IPC分类号： A61F5/56 , A61C5/14
CPC分类号： A61F5/566
摘要： A variably automated tissue retention system generally comprises an oral appliance retractably coupled to a covering which is secured to an anterior portion of the tongue. As the subject moves their tongue naturally or sleeps and the tongue becomes hypotonic, the subject's tongue may move posteriorly. As the covering pulls the tongue anteriorly or maintains a position of the tongue, the base of the tongue may be inhibited or prevented from collapsing posteriorly against the pharyngeal tissue walls and thereby allow the subject to breathe normally by automatically increasing the suction pressure on the tongue to maintain securement of the covering to the tongue as the tongue moves posteriorly.
摘要翻译：可变地自动化的组织保持系统通常包括可伸缩地联接到覆盖物的口腔器具，其被固定到舌头的前部。当主体自然地移动舌头或睡觉时，舌头变低，受试者的舌头可能向后移动。当覆盖物将舌头向前拉或保持舌头的位置时，可以抑制或防止舌头的基部向后折叠到咽组织壁，从而允许受试者通过自动增加舌头上的吸入压力而正常呼吸当舌头向后移动时，保持覆盖物到舌头的固定。

46. 发明申请

US20110180076A1 WEARABLE TISSUE RETENTION DEVICE 审中-公开
标题翻译：耐磨损组织保持装置
公开(公告)号：US20110180076A1
公开(公告)日：2011-07-28
申请号：US13045396
申请日：2011-03-10
申请人： Anant V. Hegde , Kasey Kai-Chi LI
发明人： Anant V. Hegde , Kasey Kai-Chi LI
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： A wearable tissue retention system generally comprises an oral appliance retractably coupled to a covering which is secured to an anterior portion of the tongue. As the subject moves their tongue naturally or sleeps and the tongue becomes hypotonic, the subject's tongue may move posteriorly. As the covering pulls the tongue anteriorly or maintains a position of the tongue, the base of the tongue may be inhibited or prevented from collapsing posteriorly against the pharyngeal tissue walls and thereby allow the subject to breathe normally by automatically increasing the suction pressure on the tongue to maintain securement of the covering to the tongue as the tongue moves posteriorly. The pump and electronics may be comfortably worn directly by the subject to prevent any tubing or wire entanglement.
摘要翻译：可穿戴组织保持系统通常包括可伸缩地联接到固定到舌头的前部的覆盖物的口腔器具。当主体自然地移动舌头或睡觉时，舌头变低，受试者的舌头可能向后移动。当覆盖物将舌头向前拉或保持舌头的位置时，可以抑制或防止舌头的基部向后折叠到咽组织壁，从而允许受试者通过自动增加舌头上的吸入压力而正常呼吸当舌头向后移动时，保持覆盖物到舌头的固定。泵和电子设备可以被物体直接舒适地磨损，以防止任何管道或电线缠结。

47. 发明申请

US20100319711A1 AIRWAY IMPLANT AND METHODS OF MAKING AND USING 审中-公开
公开(公告)号：US20100319711A1
公开(公告)日：2010-12-23
申请号：US12821912
申请日：2010-06-23
申请人： Anant V. Hegde , George S. Choi , Wally S. Buch
发明人： Anant V. Hegde , George S. Choi , Wally S. Buch
IPC分类号： A61F5/56
CPC分类号： A61L31/125 , A61B2017/248 , A61C7/00 , A61F2/00 , A61F5/56 , A61F5/566 , A61F2210/0023 , A61L31/14 , A61N1/0517 , A61N1/0519 , A61N1/0548 , A61N1/3601 , Y10S602/902
摘要： A system and device for maintaining and/or creating patency in airways is disclosed. The methods of using the system and device are also disclosed. The system includes a power source that energizes a electro-active polymer implant. The energized polymer implant provides stiffness and shape to the airway, thereby minimizing collapse or deformation of the airway. A method of making the device is also disclosed.
摘要翻译：公开了一种用于在气道中维持和/或产生通畅的系统和装置。还公开了使用该系统和装置的方法。该系统包括为电活性聚合物植入物通电的电源。通电的聚合物植入物为气道提供刚度和形状，从而最小化气道的塌陷或变形。还公开了制造该器件的方法。

48. 发明申请

US20090099564A1 Surgical Probe For Supporting Inflatable Therapeutic Devices In Contact With Tissue In Or Around Body Orifice And Within Tumors 有权
标题翻译：用于支持充气治疗设备的手术探针与组织内或周围的孔和肿瘤内接触
公开(公告)号：US20090099564A1
公开(公告)日：2009-04-16
申请号：US12175433
申请日：2008-07-17
申请人： Josef V. Koblish , Anant V. Hegde , David K. Swanson
发明人： Josef V. Koblish , Anant V. Hegde , David K. Swanson
IPC分类号： A61B18/18 , A61M25/10
CPC分类号： A61B18/1492 , A61B5/0422 , A61B2018/00065 , A61B2018/00083 , A61B2018/00095 , A61B2018/00214 , A61B2018/0022 , A61B2018/00238 , A61B2018/00577 , A61B2018/00839 , A61B2090/065 , A61B2218/002
摘要： A probe that facilitates the creation of lesions in bodily tissue. The probe includes a relatively short shaft and an inflatable therapeutic element.
摘要翻译：有助于在身体组织中产生损伤的探针。探针包括相对短的轴和可膨胀的治疗元件。

49. 发明授权

US06645199B1 Loop structures for supporting diagnostic and therapeutic elements contact with body tissue and expandable push devices for use with same 失效
标题翻译：用于支持诊断和治疗元件的环结构与身体组织接触并与可扩展的推动装置相接触
公开(公告)号：US06645199B1
公开(公告)日：2003-11-11
申请号：US09447180
申请日：1999-11-22
申请人： Thomas R. Jenkins , Russell B. Thompson , Robert Burnside , Anant V. Hegde , David K. Swanson
发明人： Thomas R. Jenkins , Russell B. Thompson , Robert Burnside , Anant V. Hegde , David K. Swanson
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B2018/00107 , A61B2018/00214 , A61B2018/00285 , A61B2018/00351 , A61B2018/00577 , A61B2018/00797 , A61B2018/00839 , A61B2018/1407
摘要： An apparatus that facilitates the creation of circumferential lesions in body tissue. The apparatus includes a first probe having a loop structure that supports electrodes or other operative elements against the body tissue and a second probe with an expandable push structure that may be used to urge the loop structure against body tissue.
摘要翻译：一种便于在身体组织中产生周缘损伤的装置。该装置包括具有支撑电极或抵抗身体组织的其它操作元件的环形结构的第一探针和具有可膨胀推动结构的第二探针，其可用于将环结构推向身体组织。

50. 发明授权

US06542781B1 Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue 有权
公开(公告)号：US06542781B1
公开(公告)日：2003-04-01
申请号：US09447186
申请日：1999-11-22
申请人： Josef V. Koblish , Russell B. Thompson , Thomas R. Jenkins , Anant V. Hegde
发明人： Josef V. Koblish , Russell B. Thompson , Thomas R. Jenkins , Anant V. Hegde
IPC分类号： A61N100
CPC分类号： A61B18/1492 , A61B2018/00065 , A61B2018/00077 , A61B2018/00113 , A61B2018/00148 , A61B2018/00214 , A61B2018/00375 , A61B2018/00797 , A61B2018/00821 , A61B2018/1407 , A61B2018/1435 , A61B2018/1467
摘要： A probe that facilitates the creation of circumferential lesions in body tissue. The probe includes a elongate body and a loop structure, in the form of a helical structure or other loop structure, that supports electrodes or other operative elements against the body tissue.

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