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41. 发明授权

US09364665B2 Control and/or quantification of target stimulation volume overlap and interface therefor 有权
标题翻译：目标刺激体积的控制和/或定量重叠和界面
公开(公告)号：US09364665B2
公开(公告)日：2016-06-14
申请号：US13570736
申请日：2012-08-09
申请人： Hemant Sharad Bokil , Mark Pierre , Keith Carlton , Michael A. Moffitt , Richard Mustakos , Dean Chen
发明人： Hemant Sharad Bokil , Mark Pierre , Keith Carlton , Michael A. Moffitt , Richard Mustakos , Dean Chen
IPC分类号： A61N1/36 , A61N1/372 , A61N1/05 , A61N1/08
CPC分类号： A61N1/37247 , A61N1/0534 , A61N1/0551 , A61N1/08 , A61N1/36 , A61N1/36182
摘要： A method and system include a processor that outputs a characterization of a correspondence between a volume of estimated tissue activation and a target and/or side effect stimulation volume, and/or that provides controls by which to modify thresholds and/or amounts according to which the volume of estimated activation is to correspond to the target volume.
摘要翻译：一种方法和系统包括处理器，其输出估计组织激活的体积与靶和/或副作用刺激体积之间的对应关系的表征，和/或提供用于修改阈值和/或量的控制估计激活的音量与目标音量相对应。

42. 发明授权

US08918183B2 Systems and methods for stimulation-related volume analysis, creation, and sharing 有权
标题翻译：用于刺激相关体积分析，创建和共享的系统和方法
公开(公告)号：US08918183B2
公开(公告)日：2014-12-23
申请号：US13570998
申请日：2012-08-09
申请人： Keith Carlton , Jim Cassidy , Dean Chen , Michael A. Moffitt , Dennis Zottola
发明人： Keith Carlton , Jim Cassidy , Dean Chen , Michael A. Moffitt , Dennis Zottola
IPC分类号： A61N1/08 , A61N1/36 , A61N1/372 , G06F19/00
CPC分类号： A61N1/36128 , A61N1/37235 , A61N1/37247 , G06F19/00 , G06F19/30 , G16H40/20 , G16H40/63
摘要： A computer implemented system and method facilitates a cycle of generation, sharing, and refinement of volumes related to stimulation of anatomical tissue, such as brain or spinal cord stimulation. Such volumes can include target stimulation volumes, side effect volumes, and volumes of estimated activation. A computer system and method also facilitates analysis of groups of volumes, including analysis of differences and/or commonalities between different groups of volumes.
摘要翻译：计算机实施的系统和方法有助于生成，共享和改进与解剖组织的刺激相关的体积循环，例如脑或脊髓刺激。这样的体积可以包括目标刺激体积，副作用体积和估计的活化体积。计算机系统和方法还有助于分析体积组，包括对不同体积组之间的差异和/或共同性的分析。

43. 发明申请

US20110184550A1 Controller for Controlling Combination of Hot-Runner System and Mold Assembly 有权
标题翻译：控制热流道系统和模具组装的控制器
公开(公告)号：US20110184550A1
公开(公告)日：2011-07-28
申请号：US12692916
申请日：2010-01-25
申请人： Angelo MIER , Keith Carlton , David Scott Rotondo
发明人： Angelo MIER , Keith Carlton , David Scott Rotondo
IPC分类号： B29C45/74
CPC分类号： B29C45/78 , B29C2945/76531 , B29C2945/76732 , B29C2945/76752
摘要： A single stand alone controller system (100) for controlling combination of hot-runner system (102) and mold assembly (104), assembly (104) connectable to system (102), controller system (100) comprising: processor (110); interface modules (112) configured to operatively couple to system (102) and assembly (104), processor (110) connected with modules (112); and controller-usable medium (114) embodying instructions (116) executable by processor (110), processor (110) connected with said medium (114), instructions (116) including: executable instructions for directing said processor (110) to control said system (102) and said assembly (104).
摘要翻译：用于控制热流道系统（102）和模具组件（104）的组合的单个独立控制器系统（100），可连接到系统（102）的组件（104），控制器系统（100），包括：处理器（110）; 接口模块（112），被配置为可操作地耦合到系统（102）和组件（104），与模块（112）连接的处理器（110）; 以及体现由处理器（110）执行的指令（116）的控制器可用介质（114），与所述介质（114）连接的处理器（110），指令（116）包括：用于指示所述处理器（110）控制所述系统（102）和所述组件（104）。

44. 发明授权

US5932072A Paper forming activity blade with mounting buttons 失效
标题翻译：造纸活动刀片带安装按钮
公开(公告)号：US5932072A
公开(公告)日：1999-08-03
申请号：US903623
申请日：1997-07-31
申请人： John A. Neun , Jeffrey P. Bachand , Keith Carlton , Daniel Grogan
发明人： John A. Neun , Jeffrey P. Bachand , Keith Carlton , Daniel Grogan
IPC分类号： D21F1/54 , D21F1/20 , D21F1/48 , D21F1/52
CPC分类号： D21F1/483 , D21F1/20
摘要： A papermaking apparatus such as a Fourdrinier table which includes a long blade and a trail blade. In the first aspect of the invention, the long blade includes an upper undulated surface with vents passing from the upper undulated surface to the lower surface of the long blade which is at substantially atmospheric pressure. In the second aspect of the invention, the trail blade includes an elevator-type device for adjusting the vertical position of the trail blade. In a third aspect of the invention, a single elevator is used to adjust the angle of the blade, the blade is provided as a modular or multiple-piece design, mounting buttons are used to engage slots of T-shaped cross section in the blade and/or ceramic inserts are included at wear points.
摘要翻译：一种造纸装置，例如长网，其包括长刀片和轨迹刀片。在本发明的第一方面，长刀片包括上波纹表面，其具有从处于基本大气压的长叶片的上波纹表面延伸到下表面的通气口。在本发明的第二方面中，轨道叶片包括用于调整轨道叶片的垂直位置的升降机型装置。在本发明的第三方面中，使用单个电梯来调节叶片的角度，叶片被设置为模块化或多件式设计，安装按钮用于接合叶片中的T形横截面的狭槽和/或陶瓷刀片包括在磨损点。

45. 发明授权

US10201629B2 Container system 有权
公开(公告)号：US10201629B2
公开(公告)日：2019-02-12
申请号：US15490122
申请日：2017-04-18
申请人： Keith Carlton , Oliver Carlton , Hannah Carlton
发明人： Keith Carlton , Oliver Carlton , Hannah Carlton
IPC分类号： B65D77/00 , A61L9/12
摘要： A container system having a container assembly including a lid having a fastener and an attacher, and a container having a first-cavity, and a second-cavity. A multi-purpose container system having internal cavities for varying purposes. The second-cavity having an inner volume suitable for removably containing at least one item including a scented-item for providing air freshening via ventilated perforations for odor eliminating.

46. 发明授权

US08751008B2 Remote control data management with correlation of patient condition to stimulation settings and/or with clinical mode providing a mismatch between settings and interface data 失效
标题翻译：远程控制数据管理与患者状况与刺激设置和/或临床模式相关，提供设置和界面数据之间的不匹配
公开(公告)号：US08751008B2
公开(公告)日：2014-06-10
申请号：US13571119
申请日：2012-08-09
申请人： Keith Carlton , Stephen Carcieri
发明人： Keith Carlton , Stephen Carcieri
IPC分类号： A61N1/08
CPC分类号： A61N1/36128 , A61N1/37235 , A61N1/37247 , G06F19/00 , G06F19/30 , G16H40/20 , G16H40/63
摘要： A remote control device communicatively coupled to an implanted stimulation device displays representations of modifications to stimulation settings of the implanted stimulation device according to setting change instructions input by a user, without the instructed change being implemented at the implanted stimulation device. The remote control includes an input component(s) for input of patient condition information correlated to settings of the implanted stimulation device. The implanted stimulation device cycles through stimulation programs without the remote control device indicating the changes and while the remote control device receives input of patient condition information.
摘要翻译：通信地耦合到植入的刺激装置的遥控装置根据用户输入的设置改变指令显示对植入刺激装置的刺激设置的修改的表示，而没有在植入的刺激装置上实施指示的改变。遥控器包括用于输入与植入的刺激装置的设置相关的患者状况信息的输入部件。植入的刺激装置通过刺激程序循环，而遥控装置指示变化，而遥控装置接收患者状况信息的输入。

47. 发明申请

US20120136410A1 SYSTEMS AND METHODS FOR NEUROMODULATION USING PRE-RECORDED WAVEFORMS 审中-公开
标题翻译：使用预先记录的波形进行神经网络的系统和方法
公开(公告)号：US20120136410A1
公开(公告)日：2012-05-31
申请号：US13365549
申请日：2012-02-03
申请人： Ali Rezai , Andre Machado , Keith Carlton
发明人： Ali Rezai , Andre Machado , Keith Carlton
IPC分类号： A61N1/36
CPC分类号： A61N1/36103 , A61N1/00 , A61N1/0529 , A61N1/36 , A61N1/36067 , A61N1/37229
摘要： A method is provided for neuromodulation to treat stroke. One step of the method includes recording an input waveform from a first site in the nervous system in a source subject. The first site is healthy or at least partially functioning. Next, an output waveform is applied to a second site in the nervous system of a target subject suffering from the stoke. The second site is diseased due to the stroke.
摘要翻译：提供神经调节治疗中风的方法。该方法的一个步骤包括从源对象中的神经系统中的第一位置记录输入波形。第一个网站是健康的或至少部分功能。接下来，输出波形被施加到遭受脚蹬的目标对象的神经系统中的第二位置。第二个部位由于中风而患病。

48. 发明授权

US08112154B2 Systems and methods for neuromodulation using pre-recorded waveforms 有权
标题翻译：使用预先记录的波形进行神经调节的系统和方法
公开(公告)号：US08112154B2
公开(公告)日：2012-02-07
申请号：US11943344
申请日：2007-11-20
申请人： Ali Rezai , Andre Machado , Keith Carlton
发明人： Ali Rezai , Andre Machado , Keith Carlton
IPC分类号： A61N1/05
CPC分类号： A61N1/36067 , A61B5/0476 , A61B5/11 , A61B5/1106 , A61B5/4047 , A61B5/4052 , A61B5/6814 , A61N1/0529 , A61N1/36071
摘要： Methods for neuromodulation using waveform signals. In certain embodiments, an input waveform is obtained from a signal source site in a source subject and an output waveform is applied to a target site in a target subject. The source subject is a human or animal and the signal source site is in the nervous system, including the brain. The source subject and target subject are the same subjects or different subjects. The output waveform is identical to the input waveform or derived from the input waveform. In some embodiments, the output waveform is modified in response to physiologic feedback. Also provided are systems for neuromodulation using waveform signals.
摘要翻译：使用波形信号进行神经调节的方法。在某些实施例中，从源对象中的信号源站点获得输入波形，并且将输出波形应用于目标对象中的目标位置。来源主题是人或动物，信号源位置在神经系统中，包括大脑。来源科目和目标科目是相同的科目或不同科目。输出波形与输入波形相同或从输入波形导出。在一些实施例中，响应于生理反馈修改输出波形。还提供了使用波形信号进行神经调节的系统。

49. 发明授权

US07330764B2 Implantable medical electrical stimulation lead fixation method and apparatus 有权
标题翻译：植入式医用电刺激铅固定方法及装置
公开(公告)号：US07330764B2
公开(公告)日：2008-02-12
申请号：US10833761
申请日：2004-04-28
申请人： John M. Swoyer , Keith Carlton , Martin T. Gerber , George J. Mamo , Michele Spinelli , Steven David Hartle
发明人： John M. Swoyer , Keith Carlton , Martin T. Gerber , George J. Mamo , Michele Spinelli , Steven David Hartle
IPC分类号： A61N1/18
CPC分类号： A61N1/0558 , A61N1/0551
摘要： An implantable medical electrical lead particularly for stimulation of the sacral nerves comprises a lead body extending between a distal end and a proximal end, and the distal end having at least one electrode of an electrode array extending longitudinally from the distal end toward the proximal end. The lead body at its proximal end may be coupled to a pulse generator, additional intermediate wiring, or other stimulation device. A fixation mechanism is formed on or integrally with the lead body proximal to the electrode array that is adapted to be implanted in and engage subcutaneous tissue, particularly muscle tissue, to inhibit axial movement of the lead body and dislodgement of the stimulation electrodes. The fixation mechanism comprises a M tine elements arrayed in a tine element array along a segment of the lead proximal to the stimulation electrode array. Each tine element comprises at least N flexible, pliant, tines, each tine having a tine width and thickness and extending through a tine length from an attached tine end to a free tine end. The attached tine end is attached to the lead body from a tine attachment site and supports the tine extending outwardly of the lead body and proximally toward the lead proximal end. The M×N tines are adapted to be folded inward against the lead body when fitted into and constrained by the lumen of an introducer such that the tine free ends of more distal tines of more distal tine elements are urged toward or alongside the attached tine ends of the adjacent more proximal tines of more proximal tine elements, and the folded tines do not overlap one another.
摘要翻译：特别是用于刺激骶神经的可植入医用电气引线包括在远端和近端之间延伸的引线体，并且远端具有从远端向近端纵向延伸的电极阵列的至少一个电极。其近端的引线体可以耦合到脉冲发生器，附加的中间布线或其它刺激装置。在与电极阵列接近的引线体上形成一体的固定机构，该固定机构适于被植入并接合皮下组织，特别是肌肉组织，以抑制引线体的轴向移动和刺激电极的移动。固定机构包括沿着靠近刺激电极阵列的引线的段排列在齿元件阵列中的M元件。每个齿元件包括至少N个柔性，柔韧的尖齿，每个齿具有齿的宽度和厚度并且延伸穿过齿长从附接的齿端延伸到游离齿端。附着的尖端从齿附着位置附接到引线本体，并且支撑从引线主体向外延伸并向近端朝向引线近端的齿。 MxN齿适合于当插入导引器的内腔并被约束的引导体时向内折叠，使得更远端的尖齿元件的更远远的尖齿的齿自由端朝着或与其相连的齿端被推向相邻的更接近的尖齿元件的近端齿，并且折叠的齿不相互重叠。

50. 发明申请

US20060129218A1 Implantable medical electrical stimulation lead fixation method and apparatus 有权
公开(公告)号：US20060129218A1
公开(公告)日：2006-06-15
申请号：US11352552
申请日：2006-02-13
申请人： John Swoyer , Keith Carlton , Martin Gerber , George Mamo , Michele Spinelli , Steven Hartle
发明人： John Swoyer , Keith Carlton , Martin Gerber , George Mamo , Michele Spinelli , Steven Hartle
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61N1/0551
摘要： An implantable medical electrical lead particularly for stimulation of the sacral nerves comprises a lead body extending between a distal end and a proximal end, and the distal end having at least one electrode of an electrode array extending longitudinally from the distal end toward the proximal end. The lead body at its proximal end may be coupled to a pulse generator, additional intermediate wiring, or other stimulation device. A fixation mechanism is formed on or integrally with the lead body proximal to the electrode array that is adapted to be implanted in and engage subcutaneous tissue, particularly muscle tissue, to inhibit axial movement of the lead body and dislodgement of the stimulation electrodes. The fixation mechanism comprises a M tine elements arrayed in a tine element array along a segment of the lead proximal to the stimulation electrode array. Each tine element comprises at least N flexible, pliant, tines, each tine having a tine width and thickness and extending through a tine length from an attached tine end to a free tine end. The attached tine end is attached to the lead body from a tine attachment site and supports the tine extending outwardly of the lead body and proximally toward the lead proximal end. The M×N tines are adapted to be folded inward against the lead body when fitted into and constrained by the lumen of an introducer such that the tine free ends of more distal tines of more distal tine elements are urged toward or alongside the attached tine ends of the adjacent more proximal tines of more proximal tine elements, and the folded tines do not overlap one another.

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