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41. 发明授权

US07724865B2 System and method of optimizing a monochromatic representation of basis material decomposed CT images 失效
标题翻译：优化基材分解CT图像的单色表示的系统和方法
公开(公告)号：US07724865B2
公开(公告)日：2010-05-25
申请号：US11843031
申请日：2007-08-22
申请人： Xiaoye Wu , John Eric Tkaczyk , James W. LeBlanc
发明人： Xiaoye Wu , John Eric Tkaczyk , James W. LeBlanc
IPC分类号： A61B6/00
CPC分类号： A61B6/4035 , A61B6/032 , A61B6/4233 , A61B6/4241 , A61B6/4411 , A61B6/469 , A61B6/482 , A61B6/505 , A61B6/5205 , A61B6/5235 , G01T1/249 , G06T5/002 , G06T5/50 , G06T11/008 , G06T2207/10081 , G06T2207/20216 , G06T2207/30004 , G06T2207/30112 , H01L27/14676
摘要： A system and method of a diagnostic imaging system includes a high frequency electromagnetic energy source that emits a beam of high frequency electromagnetic energy toward an object to be imaged, a detector that receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source and attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to obtain CT scan data with two or more incident energy spectra, decompose the obtained CT scan data into projection CT data of two or more basis materials, reconstruct linearly weighted projections of the two or more basis materials, determine an optimized energy for the two or more basis materials within a region-of-interest (ROI), and form a monochromatic image of the projection CT data at the optimized energy using the two or more basis material projections.
摘要翻译：诊断成像系统的系统和方法包括：高频电磁能源，其向待成像对象发射高频电磁能束;检测器，其接收高频电磁能源发射的高频电磁能量，并衰减通过该目的，可操作地连接到检测器的数据采集系统（DAS）和可操作地连接到DAS的计算机。计算机被编程以获得具有两个或更多个入射能谱的CT扫描数据，将获得的CT扫描数据分解成两个或更多个基础材料的投影CT数据，重建两个或多个基础材料的线性加权投影，确定优化的能量对于感兴趣区域（ROI）中的两个或更多个基础材料，并且使用两个或更多个基础材料投影在优化的能量下形成投影CT数据的单色图像。

42. 发明授权

US07391844B2 Method and apparatus for correcting for beam hardening in CT images 失效
标题翻译：用于校正CT图像中的束硬化的方法和装置
公开(公告)号：US07391844B2
公开(公告)日：2008-06-24
申请号：US11036618
申请日：2005-01-14
申请人： Xiaoye Wu , Piero Ugo Simoni , Thomas Louis Toth , Neil Barry Bromberg
发明人： Xiaoye Wu , Piero Ugo Simoni , Thomas Louis Toth , Neil Barry Bromberg
IPC分类号： A61B6/00
CPC分类号： A61B6/488 , A61B6/032 , A61B6/482 , A61B6/583
摘要： A method for determining a correction for beam hardening in CT images includes obtaining air scans at a plurality of kVp's, determining detection efficiencies for detector elements of the CT imaging apparatus, and estimating projection values through a combination of at least two different materials of different thicknesses. The method further includes determining a transfer function that translates the estimated projection values into ideal projection values for at least two of the different materials and storing the transfer function as the beam hardening correction for images of the CT imaging apparatus.
摘要翻译：用于确定CT图像中的束硬化校正的方法包括以多个kVp获得空气扫描，确定CT成像装置的检测器元件的检测效率，以及通过组合至少两种不同厚度的不同厚度的材料来估计投影值。该方法还包括确定将估计的投影值转换为不同材料中的至少两种的理想投影值并将传递函数存储为CT成像装置的图像的束硬化校正的传递函数。

43. 发明申请

US20080137803A1 DIAGNOSTIC IMAGING TWO NON K-EDGE BASIS MATERIALS PLUS N K-EDGE CONTRAST AGENTS 有权
标题翻译：诊断成像两个非K边缘基础材料
公开(公告)号：US20080137803A1
公开(公告)日：2008-06-12
申请号：US11608162
申请日：2006-12-07
申请人： Xiaoye Wu , Robert F. Senzig , Deborah Joy Walter , James W. LeBlanc , John Eric Tkaczyk
发明人： Xiaoye Wu , Robert F. Senzig , Deborah Joy Walter , James W. LeBlanc , John Eric Tkaczyk
IPC分类号： A61B6/00 , G12B13/00
CPC分类号： A61B6/4241 , A61B6/032 , A61B6/481 , A61B6/482 , A61B6/583
摘要： A diagnostic imaging system in an example comprises a high frequency electromagnetic energy source, a detector, a data acquisition system (DAS), and a computer. The high frequency electromagnetic energy source emits a beam of high frequency electromagnetic energy toward an object to be imaged and be resolved by the system. The detector receives high frequency electromagnetic energy emitted by the high frequency electromagnetic energy source. The DAS is operably connected to the detector. The computer is operably connected to the DAS and programmed to employ an inversion table or function to convert N+2 measured projections at different incident spectra into material specific integrals for N+2 materials that comprise two non K-edge basis materials and N K-edge contrast agents. N comprises an integer greater than or equal to 1.
摘要翻译：示例中的诊断成像系统包括高频电磁能源，检测器，数据采集系统（DAS）和计算机。高频电磁能源向待成像对象发射高频电磁能束，并由系统解决。检测器接收高频电磁能源发出的高频电磁能。 DAS可操作地连接到检测器。计算机可操作地连接到DAS并被编程为采用反演台或功能来将不同入射光谱下的N + 2个测量的投影转换为包含两个非K边缘基础材料的N + 2材料的材料特定积分，并且N K- 边缘造影剂。 N包括大于或等于1的整数。

44. 发明申请

US20080101535A1 DISTINCT INCIDENT ENERGY SPECTRA DETECTION 有权
标题翻译：不同的发生能量光谱检测
公开(公告)号：US20080101535A1
公开(公告)日：2008-05-01
申请号：US11553411
申请日：2006-10-26
申请人： Xiaoye Wu , James W. LeBlanc , Samit Kumar Basu
发明人： Xiaoye Wu , James W. LeBlanc , Samit Kumar Basu
IPC分类号： H05G1/60 , A61B6/00 , G01N23/00 , G21K1/12
CPC分类号： A61B6/405 , A61B6/032 , A61B6/4241 , A61B6/482 , A61B6/5235 , G01T1/2985
摘要： A CT system in an example comprises one or more high frequency electromagnetic energy sources, a detection assembly, a data acquisition system (DAS), and a computer. The one or more high frequency electromagnetic energy sources emit one or more beams of high frequency electromagnetic energy toward an object to be imaged. The detection assembly is capable of measuring a plurality of projection data at a same projection path that corresponds to a plurality of distinct incident energy spectra. The detection assembly comprises one or more energy discriminating (ED) detectors and/or one or more energy integration (EI) detectors that receive high frequency electromagnetic energy emitted by the one or more high frequency electromagnetic energy sources. The data acquisition system (DAS) is operably connected to the one or more ED detectors and/or the one or more EI detectors. The computer is operably connected to the DAS.
摘要翻译：示例中的CT系统包括一个或多个高频电磁能源，检测组件，数据采集系统（DAS）和计算机。一个或多个高频电磁能源朝向要成像的物体发射一个或多个高频电磁能量束。检测组件能够在对应于多个不同入射能谱的相同投影路径上测量多个投影数据。检测组件包括一个或多个能量识别（ED）检测器和/或接收由一个或多个高频电磁能源发射的高频电磁能的一个或多个能量积分（EI）检测器。数据采集系统（DAS）可操作地连接到一个或多个ED检测器和/或一个或多个EI检测器。计算机可操作地连接到DAS。

45. 发明授权

US07031426B2 Methods and system for detecting components of plaque 有权
标题翻译：检测斑块成分的方法和系统
公开(公告)号：US07031426B2
公开(公告)日：2006-04-18
申请号：US10625437
申请日：2003-07-23
申请人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
发明人： Maria Iatrou , Ricardo Scott Avila , Peter Michael Edic , Jiang Hsieh , James Walter LeBlanc , Xiaoye Wu
IPC分类号： A61B6/03
CPC分类号： A61B5/02007 , A61B6/032 , A61B6/4035 , A61B6/405 , A61B6/4241 , A61B6/481 , A61B6/482 , A61B6/583 , A61B17/22 , A61B2090/374 , A61B2090/376
摘要： A method including detecting components of plaque using a multi-energy computed tomography (MECT) system is provided.
摘要翻译：提供了一种使用多能计算机断层摄影（MECT）系统检测斑块成分的方法。

46. 发明申请

US20050259784A1 Methods for spectrally calibrating CT imaging apparatus detectors 有权
标题翻译：频谱校准CT成像装置检测器的方法
公开(公告)号：US20050259784A1
公开(公告)日：2005-11-24
申请号：US10850009
申请日：2004-05-20
申请人： Xiaoye Wu , Neil Bromberg , Alexander Kolker , Piero Simoni , Thomas Toth
发明人： Xiaoye Wu , Neil Bromberg , Alexander Kolker , Piero Simoni , Thomas Toth
IPC分类号： A61B6/00 , A61B6/03 , G01N23/00 , G21K1/12 , H05G1/60
CPC分类号： A61B6/583 , A61B6/032 , A61B6/585
摘要： A method for calibrating a computed tomographic imaging apparatus having a gantry, a radiation source operable at a plurality of kVp's, and a detector array having a plurality of detector elements includes using a system detection function to estimate signals of each detector element that would have been detected through air and through a given thickness of water to determine estimated datasets. The estimated datasets are used to determine data pair sets each comprising a normalized water projection value and an ideal projection value for each detector element. The method further includes determining and storing a representation of a mapping function of the normalized water projections values to the ideal projection values in a memory of the computed tomographic imaging apparatus as a spectral calibration of the computed tomographic imaging apparatus.
摘要翻译：一种用于校准具有台架的计算机断层成像设备的方法，可在多个kVp处操作的辐射源以及具有多个检测器元件的检测器阵列的方法包括使用系统检测功能来估计已经被检测到的每个检测器元件的信号通过空气和通过给定厚度的水检测以确定估计的数据集。估计的数据集用于确定每个包括每个检测器元件的归一化水投影值和理想投影值的数据对集合。该方法还包括将计算机断层成像设备的存储器中的归一化水投影值的映射函数的映射函数确定和存储为理想投影值，作为计算机断层成像设备的光谱校准。

47. 发明授权

US06848827B2 Method and apparatus for calibrating detector spectral response 失效
标题翻译：用于校准检测器光谱响应的方法和装置
公开(公告)号：US06848827B2
公开(公告)日：2005-02-01
申请号：US10437222
申请日：2003-05-13
申请人： Xiaoye Wu , James LeBlanc , Deborah J. Walter
发明人： Xiaoye Wu , James LeBlanc , Deborah J. Walter
IPC分类号： A61B6/00 , G01D18/00
CPC分类号： A61B6/583
摘要： The present technique provides for the spectral calibration of the detector elements of a CT detector using one or more offset calibration phantoms. The offset phantoms provide greater coverage of the detector elements as well as spectral response data associated with penetration lengths ranging in length from a minimum chord of the phantom to the diameter of the phantom. The spectral response as a function of penetration length can be obtained for each detector element by comparing the fitting of each projection view to the corresponding measured projection view over all view angles. The fitting information may then be employed to derive the coefficients of the spectral response curve for each detector element, which may in turn be employed to provide rapid correction of the spectral response for each element.
摘要翻译：本技术提供使用一个或多个偏移校准体模的CT检测器的检测器元件的光谱校准。偏移模型提供了更大的检测器元件的覆盖范围以及与从体模的最小和弦到体模直径的长度范围相关联的光谱响应数据。通过比较每个投影视图与所有视角上对应的测量投影视图的拟合，可以为每个检测器元件获得作为穿透长度的函数的光谱响应。然后可以采用拟合信息来导出每个检测器元件的光谱响应曲线的系数，其可以用于提供对于每个元件的光谱响应的快速校正。

48. 发明授权

US08385499B2 2D reflector and collimator structure and method of manufacturing thereof 有权
标题翻译： 2D反射器和准直器结构及其制造方法
公开(公告)号：US08385499B2
公开(公告)日：2013-02-26
申请号：US12647603
申请日：2009-12-28
申请人： Zhaoping Wu , Haochuan Jiang , Joseph James Lacey , James S. Vartuli , Yunfeng Sun , Qun Deng , Xiaoye Wu , Kun Tao , Zhaohui Yang
发明人： Zhaoping Wu , Haochuan Jiang , Joseph James Lacey , James S. Vartuli , Yunfeng Sun , Qun Deng , Xiaoye Wu , Kun Tao , Zhaohui Yang
IPC分类号： H05G1/00 , G21K1/02 , G21K1/00
CPC分类号： G21K1/025 , A61B6/032 , A61B6/4291 , B29D11/00596
摘要： A two dimensional collimator assembly and method of manufacturing thereof is disclosed. The collimator assembly includes a wall structure constructed to form a two dimensional array of channels to collimate x-rays. The wall structure further includes a first portion positioned proximate the object to be scanned and configured to absorb scattered x-rays and a second portion formed integrally with the first portion and extending out from the first portion away from the object to be scanned. The first portion of the wall structure has a height greater than a height of the second portion of the wall structure. The second portion of the wall structure includes a reflective material coated thereon in each of the channels forming the two dimensional array of channels.
摘要翻译：公开了二维准直器组件及其制造方法。准直器组件包括构造成形成二维阵列阵列以准直X射线的壁结构。壁结构还包括靠近待扫描物体定位的第一部分，并且被配置成吸收散射的x射线，以及第二部分与第一部分整体形成并从第一部分延伸离开被扫描物体。壁结构的第一部分的高度大于壁结构的第二部分的高度。壁结构的第二部分包括在每个通道中涂覆的反射材料，形成二维通道阵列。

49. 发明申请

US20120134561A1 METHOD AND SYSTEM FOR CORRELATED NOISE SUPPRESSION IN DUAL ENERGY IMAGING 有权
标题翻译：双能量成像中相关噪声抑制的方法与系统
公开(公告)号：US20120134561A1
公开(公告)日：2012-05-31
申请号：US12955227
申请日：2010-11-29
申请人： Dan Xu , David Allen Langan , Xiaoye Wu , Jed Douglas Pack , Andrea Marie Schmitz
发明人： Dan Xu , David Allen Langan , Xiaoye Wu , Jed Douglas Pack , Andrea Marie Schmitz
IPC分类号： G06K9/00
CPC分类号： G06T11/008 , G06T5/002 , G06T5/50 , G06T2207/10081 , G06T2211/408
摘要： Methods and systems for correlated noise suppression are presented. The present correlated noise suppression technique estimates a correlation direction between noise values in a first and a second MD image corresponding to a first and a second basis material, respectively. The two MD images are diffused using the estimated correlation direction to generate a first and a second diffused image. Further, first and second noise masks are generated by subtracting the diffused image from the corresponding MD image. Edges in the first and the second MD images are processed with the first and second noise masks, respectively to generate a final first noise mask and a final second noise mask. The first MD image is then processed with the final second noise mask to generate a final first MD image and the second MD image is processed with the final first noise mask to generate a final second MD image.
摘要翻译：提出了相关噪声抑制的方法和系统。本相关噪声抑制技术分别估计与第一和第二基础材料对应的第一和第二MD图像中的噪声值之间的相关方向。使用估计的相关方向来扩散两个MD图像以生成第一和第二扩散图像。此外，通过从相应的MD图像中减去漫射图像来产生第一和第二噪声掩码。第一和第二MD图像中的边缘分别用第一和第二噪声掩模进行处理，以产生最终的第一噪声掩模和最终的第二噪声掩模。然后用最终的第二噪声掩码处理第一MD图像以产生最终的第一MD图像，并且用最终的第一噪声掩码处理第二MD图像以产生最终的第二MD图像。

50. 发明申请

US20110249879A1 CT SPECTRAL CALIBRATION 有权
标题翻译： CT光谱校准
公开(公告)号：US20110249879A1
公开(公告)日：2011-10-13
申请号：US12976785
申请日：2010-12-22
申请人： Xiaoye Wu , Robert Franklin Senzig , Jing Zhao
发明人： Xiaoye Wu , Robert Franklin Senzig , Jing Zhao
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B6/5205 , A61B6/5229 , A61B6/583 , G06T11/005
摘要： The present disclosure relates to the performing spectral calibration of a CT imaging system. In accordance with certain embodiments, spectral calibration phantoms are scanned while positioned on a table in the imaging volume of the CT imaging system. The scans of the calibration phantoms, in conjunction with air sans performed on the CT imaging system, are used to derive information about the deviation of the measured phantom scans from an ideal. The deviation information is in turn used to derive spectral calibration vectors that may be used with the CT imaging system.
摘要翻译：本公开涉及执行CT成像系统的光谱校准。根据某些实施例，在定位在CT成像系统的成像体积的台上的同时扫描光谱校准模体。校准模型的扫描结合在CT成像系统上执行的空气，用于得到关于测量的幻影扫描与理想的偏差的信息。偏差信息又用于导出可与CT成像系统一起使用的光谱校准矢量。

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