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41. 发明申请

US20100162663A1 Packaging Solutions 有权
标题翻译：包装解决方案
公开(公告)号：US20100162663A1
公开(公告)日：2010-07-01
申请号：US12641483
申请日：2009-12-18
申请人： Joseph A. McGee , David Paul Vanderbilt , Paul L. Valint, JR.
发明人： Joseph A. McGee , David Paul Vanderbilt , Paul L. Valint, JR.
IPC分类号： B65B63/08
CPC分类号： A61L12/086 , A61L12/00 , G02B1/043 , C08L85/04 , C08L51/085 , C08L83/10
摘要： Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed.
摘要翻译：公开了用于存储诸如隐形眼镜的眼科装置的包装系统，以及用于包装这些眼科装置的方法以提供穿戴期间镜片的舒适度的解决方案。

42. 发明申请

US20100118261A1 METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES 失效
标题翻译：用于光学医疗设备的基于甲基丙烯酸酯的双链双链交联剂
公开(公告)号：US20100118261A1
公开(公告)日：2010-05-13
申请号：US12267633
申请日：2008-11-10
申请人： Joseph A. McGee , Jay F. Kunzler , Richard M. Ozark , Joseph C. Salamone
发明人： Joseph A. McGee , Jay F. Kunzler , Richard M. Ozark , Joseph C. Salamone
IPC分类号： G02C7/04 , C08G77/04 , B42D15/00 , C08L83/06
CPC分类号： C08G77/24 , C08F283/124 , C08F290/068 , C08G77/20 , G02B1/043 , Y10T428/21 , C08L51/085
摘要： Novel polymers for biomedical use, especially rigid gas permeable contact lenses that are based on bulky side-chain siloxane cross linkers. The siloxanes, either alone, or as copolymers with bulky and non-bulky mono-functional polymerizable siloxanes, fluoro monomers, such as hexafluoroisopropyl methacrylate, and hydrophilic monomers, result in transparent, high oxygen permeable polymers possessing excellent lathing and milling characteristics.
摘要翻译：用于生物医学应用的新型聚合物，特别是基于体积大的侧链硅氧烷交联剂的刚性透气隐形眼镜。单独的硅氧烷或作为与体积大和非膨松的单官能可聚合硅氧烷的共聚物，氟单体如甲基丙烯酸六氟异丙酯和亲水性单体，得到具有优异的车床和研磨特性的透明的高透氧性聚合物。

43. 发明授权

US07021761B2 Lens with colored portion and coated surface 失效
标题翻译：透镜带有彩色部分和涂层表面
公开(公告)号：US07021761B2
公开(公告)日：2006-04-04
申请号：US10187153
申请日：2002-06-28
申请人： Jay F. Künzler , Gary D. Friends , Daniel M. Ammon , Joseph A. McGee , Michael G. Gartley
发明人： Jay F. Künzler , Gary D. Friends , Daniel M. Ammon , Joseph A. McGee , Michael G. Gartley
IPC分类号： G02C7/04
CPC分类号： G02C7/021 , G02C7/046
摘要： A lens with a colored portion is composed of a lens-forming polymer having a front lens surface and a back lens surface. A colorant is applied to at least one of these surfaces, and these surfaces may be coated with a coating layer composed of a material different than the lens-forming polymer. In the case of a cosmetic contact lens, the colorant may be applied in an annular ring pattern corresponding to an iris, so that the colorant pattern masks and changes the apparent color of the natural iris when the contact lens is worn.
摘要翻译：具有着色部分的透镜由具有前透镜表面和后透镜表面的透镜形成聚合物组成。将着色剂施加到这些表面中的至少一个，并且这些表面可以涂覆有由不同于透镜形成聚合物的材料构成的涂层。在化妆品隐形眼镜的情况下，着色剂可以以对应于虹膜的环形图案施加，使得着色剂图案掩蔽和改变隐形眼镜佩戴时天然虹膜的表观颜色。

44. 发明申请

US20100168855A1 Method of Applying Renewable Polymeric Lens Coating 失效
标题翻译：应用可再生聚合物镜片涂层的方法
公开(公告)号：US20100168855A1
公开(公告)日：2010-07-01
申请号：US12641422
申请日：2009-12-18
申请人： Joseph A. McGee , David Paul Vanderbilt , Paul L. Valint, JR.
发明人： Joseph A. McGee , David Paul Vanderbilt , Paul L. Valint, JR.
IPC分类号： A61F2/02 , B05D7/00 , B65B55/02 , C08L33/04 , G02C7/04
CPC分类号： G02B1/043 , A61L27/34 , A61L29/085 , A61L31/10 , A61L2400/18 , A61L2430/16
摘要： Disclosed are biomedical devices having a hydrophilic coating on a portion of a surface thereof, the biomedical device comprising: (a) a biomedical device obtained from a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; and (b) a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer of (b) bind with the boronic acid moieties of the biomedical device of (a), thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to substantially as-new condition. Methods for treating the biomedical device are also disclosed.
摘要翻译：公开了在其表面的一部分上具有亲水涂层的生物医学装置，所述生物医学装置包括：（a）由单体混合物的聚合产物获得的生物医学装置，其包含（i）含有硼酸部分的可聚合单体和吸电子部分; 和（ii）生物医学装置形成共聚单体; 和（b）沿着聚合物链具有互补的反应性官能团的亲水性反应性聚合物，其中沿着（b）的亲水性反应性聚合物的聚合物链的互补反应性官能团与（a）的生物医学装置的硼酸部分结合，从而产生生物相容性涂层，其可以被去除并重新施加以将生物医学装置的表面性质恢复到基本上新的状态。还公开了用于治疗生物医学装置的方法。

45. 发明申请

US20090168013A1 Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains 审中-公开
标题翻译：含有极性氟化侧链的三甲基甲硅烷基封端的聚硅氧烷大分子单体
公开(公告)号：US20090168013A1
公开(公告)日：2009-07-02
申请号：US12269442
申请日：2008-11-12
申请人： Jay F. Kunzler , Richard M. Ozark , Joseph A. McGee , Joseph C. Salamone
发明人： Jay F. Kunzler , Richard M. Ozark , Joseph A. McGee , Joseph C. Salamone
IPC分类号： G02C7/04 , C07F7/02 , C08F290/06
CPC分类号： C08F290/068 , C08G77/20 , C08G77/385 , G02B1/043 , C08L51/085
摘要： A method for reducing the modulus of polymer siloxane hydrogel compositions by employing monomeric polysiloxanes endcapped with trimethylsilyl to reduce the crosslinking density of the hydrogel. The synthesis consists of a single vessel acid catalyzed ring opening polymerization and may be employed to produce copolymers useful as hydrogel contact lens materials.
摘要翻译：通过使用用三甲基甲硅烷基封端的单体聚硅氧烷降低聚合物硅氧烷水凝胶组合物的模量以降低水凝胶的交联密度的方法。该合成由单容器酸催化的开环聚合组成，可用于产生可用作水凝胶隐形眼镜材料的共聚物。

46. 发明授权

US07147326B2 Lens with colored portion and coated surface 失效
公开(公告)号：US07147326B2
公开(公告)日：2006-12-12
申请号：US11332006
申请日：2006-01-13
申请人： Jay F. Künzler , Gary D. Friends , Daniel M. Ammon , Joseph A. McGee , Michael G. Gartley
发明人： Jay F. Künzler , Gary D. Friends , Daniel M. Ammon , Joseph A. McGee , Michael G. Gartley
IPC分类号： G02C7/04
CPC分类号： G02C7/021 , G02C7/046
摘要： A lens with a colored portion is composed of a lens-forming polymer having a front lens surface and a back lens surface. A colorant is applied to at least one of these surfaces, and these surfaces may be coated with a coating layer composed of a material different than the lens-forming polymer. In the case of a cosmetic contact lens, the colorant may be applied in an annular ring pattern corresponding to an iris, so that the colorant pattern masks and changes the apparent color of the natural iris when the contact lens is worn.

47. 发明授权

US06958169B2 Surface treatment of medical device 有权
标题翻译：医疗器械表面处理
公开(公告)号：US06958169B2
公开(公告)日：2005-10-25
申请号：US10321949
申请日：2002-12-17
申请人： Jay F. Künzler , Joseph A. McGee , Joseph C. Salamone , David E. Seelye
发明人： Jay F. Künzler , Joseph A. McGee , Joseph C. Salamone , David E. Seelye
IPC分类号： A61L27/34 , A61L27/50 , A61L31/10 , A61L27/08 , G02C7/04
CPC分类号： A61L27/34 , A61L27/50
摘要： A method for improving the wettability of a medical device involves: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic device-forming monomer including a copolymerizable group and an electron donating moiety, and a second device-forming monomer including a copolymerizable group and a reactive functional group; and (b) contacting a surface of the medical device with a wetting agent including a proton donating moiety reactive with the functional group provided by the second lens-forming monomer and that complexes with the electron donating moiety provided by the hydrophilic lens-forming monomer.
摘要翻译：一种用于改善医疗装置的润湿性的方法包括：（a）提供由包含包含可共聚基团和给电子部分的亲水装置形成单体的单体混合物形成的医疗装置，以及第二装置形成单体，可共聚基团和反应性官能团; 和（b）使医疗装置的表面与包含与由第二透镜形成性单体提供的官能团反应的质子供体部分的润湿剂和与亲水性透镜形成性单体提供的给电子部分的配合物接触。

48. 发明授权

US06858310B2 Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers 失效
标题翻译：具有反应性亲水聚合物的有机硅医疗器械的可再生表面处理
公开(公告)号：US06858310B2
公开(公告)日：2005-02-22
申请号：US10427055
申请日：2003-04-30
申请人： Joseph A. McGee , Paul L. Valint, Jr. , James A. Bonafini, Jr.
发明人： Joseph A. McGee , Paul L. Valint, Jr. , James A. Bonafini, Jr.
IPC分类号： G02C7/04 , A61F9/00 , A61L27/00 , A61L27/34 , C08J7/04 , G02B1/04 , G02B1/10 , B32B9/04
CPC分类号： G02B1/043 , A61L27/34 , C08J7/047 , Y10T428/31511 , Y10T428/31663 , C08L83/00 , C08L43/04
摘要： The present invention is directed toward the renewable surface treatment of medical devices such as contact lenses and medical implants. In particular, the present invention is directed to a method of modifying the surface of a medical device to increase its biocompatibility or hydrophilicity by coating the device with a removable hydrophilic polymer by means of reaction between reactive functionalities on the hydrophilic polymer which functionalities are complementary to reactive functionalities on or near the surface of the medical device. The present invention is also directed to a contact lens or other medical device having such a surface coating.
摘要翻译：本发明涉及医疗装置如隐形眼镜和医用植入物的可再生表面处理。特别地，本发明涉及通过借助亲水性聚合物上的反应性官能团之间的反应涂覆具有可去除的亲水性聚合物的装置来改变医疗装置的表面以增加其生物相容性或亲水性的方法，其功能性与在医疗装置的表面上或附近的反应性功能。本发明还涉及具有这种表面涂层的隐形眼镜或其它医疗装置。

49. 发明授权

US5364918A Surface modification of polymer objects 失效
标题翻译：聚合物物体的表面改性
公开(公告)号：US5364918A
公开(公告)日：1994-11-15
申请号：US38384
申请日：1993-03-29
申请人： Paul L. Valint, Jr. , Joseph A. McGee , Yu-Chin Lai
发明人： Paul L. Valint, Jr. , Joseph A. McGee , Yu-Chin Lai
IPC分类号： C08F2/00 , C08F290/00 , C08F290/04 , C08F290/06 , C08F290/14 , C08F299/00 , C08J7/04 , C08L101/00 , G02B1/04 , G02C7/04 , C08F18/20 , C08F12/30 , C08F20/10
CPC分类号： C08F290/14 , C08F290/04 , G02B1/043
摘要： A method of modifying the surfaces of the polymeric objects by adding a polymerizable surfactant to the monomer mix used to form the object. Also disclosed are surface-modified objects prepared by this method, which is particularly suited for modifying the surfaces of contact lenses.
摘要翻译：通过向用于形成物体的单体混合物中加入可聚合表面活性剂来改性聚合物体的表面的方法。还公开了通过该方法制备的表面改性物体，其特别适用于改变隐形眼镜的表面。

50. 发明授权

US5336797A Siloxane macromonomers 失效
标题翻译：硅氧烷大分子单体
公开(公告)号：US5336797A
公开(公告)日：1994-08-09
申请号：US998346
申请日：1992-12-30
申请人： Joseph A. McGee , Paul L. Valint, Jr.
发明人： Joseph A. McGee , Paul L. Valint, Jr.
IPC分类号： G02C7/04 , C08F2/38 , C08F30/08 , C08F290/00 , C08F290/04 , C08F299/00 , G02B1/04 , C07F7/08 , C08F228/02 , C08F230/08
CPC分类号： C08F290/04 , C08F2/38 , G02B1/043
摘要： Siloxane macromonomers are disclosed which can be copolymerized with hydrophilic monomers or hydrophobic monomers to prepare polymeric materials useful as biomedical devices. The copolymers made from hydrophilic monomers exhibit good oxygen permeability and are particularly suitable for use in contact lenses.
摘要翻译：公开了可与亲水单体或疏水单体共聚以制备可用作生物医学装置的聚合物材料的硅氧烷大分子单体。由亲水性单体制得的共聚物表现出良好的透氧性，特别适用于隐形眼镜。

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