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41. 发明申请

US20110033426A1 USE OF MODIFIED CELLS FOR THE TREATMENT OF MULTIPLE SCLEROSIS 有权
标题翻译：用于治疗多发性硬化症的改良细胞的使用
公开(公告)号：US20110033426A1
公开(公告)日：2011-02-10
申请号：US12740502
申请日：2008-10-31
申请人： Roland Martin , Andreas Lutterotti , Stephen Miller
发明人： Roland Martin , Andreas Lutterotti , Stephen Miller
IPC分类号： A61K35/14 , C12N5/078 , A61P25/00
CPC分类号： A61K39/0008 , C07K14/4713 , C07K14/70503
摘要： The present invention describes blood cells chemically coupled with immunodominant myelin peptides and their use in the treatment of Multiple Sclerosis.
摘要翻译：本发明描述了与免疫显性髓磷脂肽化学偶联的血细胞及其在治疗多发性硬化症中的用途。

42. 发明申请

US20100093734A1 CYTOKINE INHIBITORS 有权
标题翻译：细胞因子抑制剂
公开(公告)号：US20100093734A1
公开(公告)日：2010-04-15
申请号：US12637712
申请日：2009-12-14
申请人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhijun Wang
发明人： Erik Boman , Susana Conde Ceide , Russell Dahl , Nancy G.J. Delaet , Justin Ernst , Antonio Garrido Montalban , Jeffrey Kahl , Christopher Larson , Stephen Miller , Hiroshi Nakanishi , Edward Roberts , Eddine Saiah , Robert Sullivan , Zhijun Wang
IPC分类号： A61K31/5375 , C07D295/14
CPC分类号： A61K31/416 , C07D207/40 , C07D231/12 , C07D231/40 , C07D239/47 , C07D249/12 , C07D253/075 , C07D295/088 , C07D403/12 , C07D471/04 , C07D487/04 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention provides low molecular weight compounds useful as cytokine inhibitors, and compositions thereof. In particular, compounds of the invention are useful as anti-inflammatory agents. There are further provided methods for the preparation of such agents and their use in preventing or treating conditions mediated by cytokines such as arthritis.
摘要翻译：本发明提供可用作细胞因子抑制剂的低分子量化合物及其组合物。特别地，本发明的化合物可用作抗炎剂。还提供了制备这些试剂的方法及其在预防或治疗由细胞因子如关节炎介导的病症中的用途。

43. 发明申请

US20070270313A1 Method for thinning fruit blossoms using eugenol 失效
标题翻译：使用丁香酚稀释水果开花的方法
公开(公告)号：US20070270313A1
公开(公告)日：2007-11-22
申请号：US11801622
申请日：2007-05-10
申请人： Thomas Tworkoski , Stephen Miller
发明人： Thomas Tworkoski , Stephen Miller
IPC分类号： A01N31/00
CPC分类号： A01N31/16
摘要： A method for thinning fruit blossoms involving applying an effective amount of a blossom thinning composition to the blossoms and associated living tissue (e.g., nearby buds and leaves) of fruit bearing plants (e.g., fruit trees), the blossom thinning composition comprising eugenol as an active ingredient for the purpose of blossom thinning.
摘要翻译：一种减少水果开花的方法，其涉及将有效量的开花变薄组合物施用于含果实植物（例如果树）的花朵和相关生物体组织（例如附近的芽和叶）中，所述花粉稀化组合物包含丁子香酚作为活性成分为开花变薄的目的。

44. 发明申请

US20070238627A1 Gear lubricant with low Brookfield ratio 失效
标题翻译：低布鲁克菲尔德比的齿轮润滑剂
公开(公告)号：US20070238627A1
公开(公告)日：2007-10-11
申请号：US11399773
申请日：2006-04-07
申请人： Michael Haire , John Zakarian , John Rosenbaum , Nancy Bertrand , Stephen Miller
发明人： Michael Haire , John Zakarian , John Rosenbaum , Nancy Bertrand , Stephen Miller
IPC分类号： C10M105/38
CPC分类号： C10M171/02 , C10M2201/087 , C10M2203/1085 , C10M2205/0285 , C10M2205/173 , C10M2209/084 , C10M2219/08 , C10M2223/049 , C10N2220/02 , C10N2220/022 , C10N2230/02 , C10N2230/08 , C10N2230/10 , C10N2230/12 , C10N2230/58 , C10N2230/72 , C10N2240/02 , C10N2240/04 , Y10S208/95
摘要： Gear lubricant with a low Brookfield Ratio, comprising: a base oil having sequential carbon atoms, low aromatics, greater than 20 wt % molecules with cycloparaffins and a high ratio of monocycloparaffins to multicycloparaffins; less than 22 wt % of a second base oil having less than 40 wt % molecules with cycloparaffins and a lower ratio of monocycloparaffins to multicycloparaffins; a pour point depressant, an EP additive; and less than 10 wt % VI improver. Gear lubricant with a low Brookfield Ratio, comprising a first base oil having low aromatics and high VI; less than 22 wt % of a second base oil with a lower VI; a pour point depressant; and an EP additive. Gear lubricant having a low Brookfield Ratio comprising: an FT derived base oil; a pour point depressing base oil blending component; and an EP additive. Processes for making gear lubricants with low Brookfield Ratios. Method for reducing Brookfield Ratio.
摘要翻译：具有低布鲁克菲尔德比的齿轮润滑剂，包括：具有连续碳原子的基础油，低芳族化合物，大于20重量％的具有环烷烃的分子和高比例的单环烷烃与多环烷烃; 小于22重量％的具有小于40重量％分子的第二基础油与环烷烃和较低的单环烷烃与多环烷烃的比例; 倾点抑制剂，EP添加剂; 和少于10重量％的VI改进剂。具有低布鲁克菲尔德比率的齿轮润滑剂，包括具有低芳族化合物和高VI的第一基础油; 少于22重量％的具有较低VI的第二基础油; 倾点抑制剂; 和EP添加剂。具有低布鲁克菲尔德比率的齿轮润滑剂包括：FT衍生的基础油; 一种倾点降低的基础油混合组分; 和EP添加剂。制造具有低布鲁克菲尔德比率的齿轮润滑剂的方法。降低布鲁克菲尔德率的方法。

45. 发明申请

US20070187291A1 HIGHLY PARAFFINIC, MODERATELY AROMATIC DISTILLATE FUEL BLEND STOCKS PREPARED BY LOW PRESSURE HYDROPROCESSING OF FISCHER-TROPSCH PRODUCTS 审中-公开
标题翻译：高效液相色谱法，由FISCHER-TROPSCH产品的低压水解制备的中等芳烃蒸馏燃料混合物
公开(公告)号：US20070187291A1
公开(公告)日：2007-08-16
申请号：US10464546
申请日：2003-06-19
申请人： Stephen Miller , Dennis O'Rear
发明人： Stephen Miller , Dennis O'Rear
IPC分类号： C10L1/04 , C10G65/02 , C10G69/02
CPC分类号： C10L1/08 , C10G2400/04 , C10L1/04
摘要： The invention relates to a distillate fuel comprising a highly paraffinic, moderately aromatic distillate fuel blend stock. The highly paraffinic, moderately aromatic distillate fuel blend stock exhibits excellent combustion properties in diesel and jet engines as a result of the high paraffin content. In addition, the highly paraffinic, moderately aromatic distillate fuel blend stock exhibits improved seal-swell characteristics as a result of the moderate aromatic content. The blend stock is preferably prepared from a Fischer-Tropsch derived product that is hydroprocessed under conditions during which a moderate amount of aromatics are formed.
摘要翻译：本发明涉及一种包含高度链烷烃，中等芳香族馏分燃料混合原料的馏出物燃料。由于高石蜡含量，高度链烷烃，中等芳香族馏分燃料混合原料在柴油和喷气发动机中表现出优异的燃烧性能。此外，由于中等芳族化合物含量，高度链烷烃，中等芳香族馏分燃料混合原料表现出改进的密封膨胀特性。共混料优选由费托衍生的产物制备，其在形成中等量芳族化合物的条件下进行加氢处理。

46. 发明申请

US20070081194A1 FLEXOGRAPHIC PRINTING 有权
标题翻译：灵活印刷
公开(公告)号：US20070081194A1
公开(公告)日：2007-04-12
申请号：US11611178
申请日：2006-12-15
申请人： Devon McCrea , Stephen Miller
发明人： Devon McCrea , Stephen Miller
IPC分类号： H04N1/29
CPC分类号： G03F7/2022 , B41C1/00 , B41C1/02 , B41C1/05 , B41M1/04 , B41N1/12 , G03F5/12 , G03F7/2055 , H04N1/405 , H04N1/4057
摘要： A method of screening a continuous tone image into a halftone representation for a flexographic printing operation can compensate for characteristic printing problems in highlight areas by selectively placing non-printing dots or pixels proximate highlight dots. The non-printing dots or pixels raise the printing relief floor in the highlight areas providing additional support for marginally printable image features.
摘要翻译：将连续色调图像筛选为用于柔性版印刷操作的半色调表示的方法可以通过选择性地将非印刷点或像素放置在高亮点附近来补偿高光区域中的特征印刷问题。非打印点或像素在突出显示区域中提高了印刷浮雕层，为边缘打印图像特征提供了额外的支持。

47. 发明申请

US20060289337A1 Process for making lubricating base oils with high ratio of monocycloparaffins to multicycloparaffins 失效
标题翻译：制造具有高比例的单环烷烃的润滑基础油与多环烷烃的方法
公开(公告)号：US20060289337A1
公开(公告)日：2006-12-28
申请号：US11438108
申请日：2006-05-19
申请人： John Rosenbaum , Nancy Bertrand , Scott Deskin , Kamala Krishna , Stephen Miller , Susan Abernathy
发明人： John Rosenbaum , Nancy Bertrand , Scott Deskin , Kamala Krishna , Stephen Miller , Susan Abernathy
IPC分类号： C10G73/02
CPC分类号： C10G45/64 , C10G2/32 , C10G65/043 , C10G2400/10 , Y10S208/95
摘要： A process for manufacturing a lubricating base oil, comprising dewaxing a substantially paraffinic wax feed by hydroisomerization dewaxing using a shape selective intermediate pore size molecular sieve under hydroisomerization conditions including a hydrogen to feed ratio from about 712.4 to about 3562 liter H2/liter oil, whereby a lubricating base oil is produced having a)a total weight percent of molecules with cycloparaffinic functionality greater than 10, and b) a ratio of weight percent molecules with monocycloparaffinic functionality to weight percent molecules with multicycloparaffinic functionality greater than 30. Also a method for producing a base oil having a high ratio of weight percent molecules with monocycloparaffinic functionality to weight percent molecules with multicycloparaffinic functionality by hydroisomerization dewaxing a selected Fischer-Tropsch wax under hydroisomerization conditions including a hydrogen to feed ratio from about 712.4 to about 3562 liter H2/liter oil. Also a lubricating base oil manufacturing plant.
摘要翻译：一种润滑油基础油的制造方法，其特征在于，在加氢异构化条件下，通过使用形状选择性中等孔径分子筛，通过加氢异构化脱蜡将大体上链烷烃化的蜡进料脱蜡，所述加氢异构化条件包括氢与进料比约为712.4〜3562升H 2， / l油，由此产生润滑基础油，其具有a）具有大于10的环烷烃官能团的分子的总重量百分比，以及b）分子与单环烷烃官能团的重量百分比与重均分子百分比的多环烷烃官能团的比例更大 30.另外，通过在加氢异构化条件下加氢异构化脱蜡选择的费 - 托蜡来生产具有高单体重量百分比的分子与单环烷属官能度的重量百分比的基础油的方法，其中多烷基官能度分子的重量百分比为约712.4 至约3562 升H 2 /升/升油。也是润滑油基础油生产厂。

48. 发明申请

US20050274845A1 Lightweight air vehicle and pneumatic launcher 有权
标题翻译：轻型机动车和气动发射器
公开(公告)号：US20050274845A1
公开(公告)日：2005-12-15
申请号：US10509659
申请日：2004-02-19
申请人： Stephen Miller , Matthew Velazquez
发明人： Stephen Miller , Matthew Velazquez
IPC分类号： B64B20060101 , B64B1/00 , B64C3/56 , B64C39/02 , B64F1/04 , B64F1/06
CPC分类号： B64C39/024 , B64C2201/021 , B64C2201/042 , B64C2201/084 , B64C2201/102 , B64C2201/165 , B64C2201/201 , B64C2201/203 , B64F1/06
摘要： A portable unmanned air vehicle and launcher system is provided that includes a foldable unmanned air vehicle having a pressure tube; a launch gas reservoir for holding launch gas; a launch tube operatively connected to the launch gas reservoir and having a free end that is positioned in the pressure tube of the air vehicle; a free piston positioned within the launch tube; and a free piston stop to prevent the free piston from leaving the launch tube. A first portion of the launch gas in the launch gas reservoir is released into the launch tube and forces the free piston from an initial position to an end position at which the free piston is stopped by the free piston stop.
摘要翻译：提供了一种便携式无人驾驶飞行器和发射系统，其包括具有压力管的可折叠无人驾驶飞行器; 用于发射气体的发射气藏; 操作地连接到发射气体储存器并具有位于空中载体的压力管中的自由端的发射管; 位于发射管内的自由活塞; 和自由活塞止挡件，以防止自由活塞离开发射管。发射气体储存器中的发射气体的第一部分被释放到发射管中，并且将自由活塞从初始位置推动到自由活塞由自由活塞停止的终止位置。

49. 发明申请

US20050271583A1 Preparation of molecular sieves involving spray drying 有权
公开(公告)号：US20050271583A1
公开(公告)日：2005-12-08
申请号：US11107496
申请日：2005-04-14
申请人： Stephen Miller , David Cooper , Gerald Woltermann , William Cormier
发明人： Stephen Miller , David Cooper , Gerald Woltermann , William Cormier
IPC分类号： B01J21/00 , B01J29/00 , C01B33/36 , C01B37/02 , C01B39/00 , C01B39/40 , C01B39/48 , C01F7/00
CPC分类号： C01B39/40 , C01B37/02 , C01B39/48 , Y10S423/22 , Y10S423/27
摘要： Molecular sieves are prepared by forming a reaction mixture slurry, spray drying the reaction mixture slurry to form particles, and heating the spray dried reaction mixture at a temperature and pressure sufficient to cause crystallization of the molecular sieve. The reaction mixture contains an organic templating agent capable of forming the molecular sieve. The template may be added to the reaction mixture either by adding all of the template prior to spray drying, or by adding a portion of the template prior to spray drying with the remainder being added after spray drying.

50. 发明申请

US20050261145A1 Lubricant blends with low brookfield viscosities 有权
标题翻译：润滑剂与低布氏粘度混合
公开(公告)号：US20050261145A1
公开(公告)日：2005-11-24
申请号：US10847997
申请日：2004-05-19
申请人： John Rosenbaum , Stephen Miller , Joseph Pudlak
发明人： John Rosenbaum , Stephen Miller , Joseph Pudlak
IPC分类号： C10M157/00 , C10M169/04 , C10M11/02
CPC分类号： C10M169/041 , C10M169/04 , C10M2203/1006 , C10M2205/02 , C10M2205/022 , C10M2205/024 , C10M2205/026 , C10M2205/028 , C10M2205/173 , C10M2209/04 , C10M2209/084 , C10M2209/086 , C10M2209/101 , C10M2211/08 , C10M2217/024 , C10N2220/021 , C10N2220/022 , C10N2220/025 , C10N2230/02 , C10N2230/08 , C10N2240/04 , C10M2209/062 , C10M2205/04
摘要： Lubricant blends and finished gear oils comprising a Fischer-Tropsch derived lubricant base oil fraction, a petroleum derived base oil, and a pour point depressant are provided. The Fischer-Tropsch derived lubricant base oil fraction comprises less than 0.30 weight percent aromatics, greater than 5 weight percent molecules with cycloparaffinic functionality, and a ratio of weight percent of molecules with monocycloparaffinic functionality to weight percent of molecules with multicycloparaffnic functionality greater than 15. The petroleum derived base oils comprises greater than 90 weight percent saturates and less than 300 ppm sulfur and is preferably selected from the group consisting of a Group II base oil, a Group III base oil, and mixtures thereof. These lubricant blends have surprising low Brookfield viscosities at −40° C.
摘要翻译：提供了包含费 - 托衍生的润滑剂基础油馏分，石油衍生的基础油和倾点下降剂的润滑剂混合物和成品齿轮油。费 - 托衍生的润滑剂基础油馏分包含小于0.30重量％的芳族化合物，大于5重量％的具有环烷烃官能团的分子，以及具有单环烷烃官能团的分子的重量百分比与多环烷烃官能度大于15的分子的重量百分比的比率。石油衍生的基础油包含大于90重量％的饱和物和小于300ppm的硫，并且优选选自第II组基础油，III族基础油及其混合物。这些润滑剂混合物在-40°C时具有惊人的低Brookfield粘度。

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