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    • 42. 发明授权
    • Point-based customer tracking and maintenance incentive system
    • 基于点的客户跟踪和维护激励系统
    • US07698149B2
    • 2010-04-13
    • US10929949
    • 2004-08-31
    • Hiroshi NishikawaYouichi ArakiKiichi Hama
    • Hiroshi NishikawaYouichi ArakiKiichi Hama
    • G06Q10/00G06F15/173
    • G06Q10/10G06Q10/20G06Q30/02G06Q30/0207G06Q30/0208G06Q30/0212
    • A computer terminal 110 connected to a manufacturing apparatus 120 as an object of the maintenance management is connected to a server machine 210 providing a maintenance management service by a network 500, enabling bi-directional communication. The computer terminal transmits status information on an apparatus as an object of the maintenance management to the server machine in response to a status information transmission request received from a server at every predetermined interval. The server machine includes a status point information management database for storing status points generated according to status information and determines whether status information has been received at every predetermined interval. Each time it is determined that status information is received, a predetermined point is added so as to update the status points of the status point information management database. This can encourage a customer to perform maintenance by him/herself and reduce workload of a serviceman.
    • 连接到作为维护管理对象的制造装置120的计算机终端110连接到由网络500提供维护管理服务的服务器机器210,从而实现双向通信。 计算机终端响应于从每个预定间隔从服务器接收到的状态信息发送请求,将关于作为维护管理对象的装置的状态信息发送到服务器机器。 服务器机器包括状态点信息管理数据库,用于存储根据状态信息生成的状态点,并且确定是否已经以每个预定间隔接收到状态信息。 每次确定接收到状态信息时,添加预定点以更新状态点信息管理数据库的状态点。 这可以鼓励客户自己进行维护,减少维修人员的工作量。
    • 43. 发明授权
    • Image reading device
    • 图像读取装置
    • US07649656B2
    • 2010-01-19
    • US11009462
    • 2004-12-13
    • Noritoshi MaruchiHiroshi NishikawaKazuhiro Ishiguro
    • Noritoshi MaruchiHiroshi NishikawaKazuhiro Ishiguro
    • H04N1/46G06F15/00
    • H04N1/00013H04N1/00002H04N1/00037H04N1/00063H04N1/00082H04N1/00909H04N1/12H04N1/193H04N1/4097
    • An image reading device capable of detecting foreign particles on a transparent member by including the transparent member, a conveyance unit that conveys an original document to the transparent member, a reading unit that reads via the transparent member an image of the original document being conveyed on the transparent member at multiple reading positions that exist with a prescribed distance therebetween along an original document conveyance direction, an output unit that outputs signals for different color components corresponding to each of the reading positions, a transparent member moving unit that moves the transparent member in a prescribed direction such that the original document slides over the transparent member while being conveyed to the reading positions during image reading, and a detector that detects noise components caused by foreign particles on the transparent member based on the output signals from the output unit.
    • 一种能够通过包括透明构件来检测透明构件上的异物的图像读取装置,将原始文件传送到透明构件的传送单元,读取单元,其通过透明构件读取正在传送的原始文档的图像 沿着原稿传送方向以规定距离存在的多个读取位置的透明构件,输出与各读取位置对应的不同颜色成分的信号的输出单元,使透明构件移动到的透明构件移动单元 规定的方向,使得原稿在图像读取期间被传送到读取位置时在透明构件上滑动;以及检测器,其基于来自输出单元的输出信号,检测由透明构件上的异物引起的噪声分量。
    • 44. 发明申请
    • PHARMACEUTICAL COMPOSITION AND METHOD USING ANTIFUNGAL AGENT IN COMBINATION
    • 药物组合物和使用抗真菌剂组合的方法
    • US20090087480A1
    • 2009-04-02
    • US11910999
    • 2006-04-05
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • Nobuhiko NomuraHiroshi NishikawaNoritomo Fujino
    • A61K9/127A61K31/44A61K31/496A61K31/436A61P31/10A61K31/422A61K31/497A61K31/4196
    • A61K45/06A61K31/4196A61K31/445A61K31/7048A61K2300/00
    • A pharmaceutical composition containing one or more antifungal agents selected from an arylamidine derivative represented by the general formula: (wherein R1 represents an amidino group that may be substituted with a hydroxyl group that may be protected with an acyl group, an amidino group that may be substituted with an alkoxy group that may be substituted, or an amidino group that may be substituted with an aralkyloxy group that may be substituted; R2 and R3 identically or differently represent a hydrogen atom or a halogen atom) or a salt thereof, an azole antifungal agent, a polyene antifungal agent, a candin antifungal agent and a fluoropyrimidine antifungal agent has a strong antifungal activity and is useful for the treatment of fungal infection. A method for using them in combination is useful as an excellent therapeutic method for fungal infection. A pharmaceutical composition containing the arylamidine derivative represented by the above general formula or a salt thereof and an immunosuppressant has a strong antifungal activity and is useful for the treatment of fungal infection and a skin disease such as atopic dermatitis. A method for using them in combination is useful as an excellent therapeutic method for fungal infection and a skin disease such as atopic dermatitis.
    • 一种含有一种或多种抗真菌剂的药物组合物,其选自由以下通式表示的芳基脒衍生物:(其中R1表示可被可被酰基保护的羟基取代的脒基,可以是酰基的脒基) 被可被取代的烷氧基取代,或被可被取代的芳烷氧基取代的脒基; R2和R3相同或不同地表示氢原子或卤素原子)或其盐,唑类抗真菌剂 药剂,多烯抗真菌剂,栀子抗真菌剂和氟嘧啶抗真菌剂具有很强的抗真菌活性,可用于治疗真菌感染。 组合使用它们的方法可用作真菌感染的优良治疗方法。 含有上述通式所示的芳基脒衍生物或其盐和免疫抑制剂的药物组合物具有很强的抗真菌活性,可用于治疗真菌感染和皮肤病如特应性皮炎。 组合使用它们的方法可用作真菌感染和皮肤疾病如特应性皮炎的优异治疗方法。
    • 46. 发明申请
    • Ascorbic acid derivatives and skin-whitening cosmetics
    • 抗坏血酸衍生物和美白化妆品
    • US20080253982A1
    • 2008-10-16
    • US11889158
    • 2007-08-09
    • Hiroharu ShibayamaKoichi UedaHachiro IndoSatoshi TachibanaHiroshi NishikawaMasaru Yamabe
    • Hiroharu ShibayamaKoichi UedaHachiro IndoSatoshi TachibanaHiroshi NishikawaMasaru Yamabe
    • A61K8/55A61K31/665A61Q19/02
    • A61Q19/02A61K8/676C07F9/65515
    • It is an object to provide an L-ascorbic acid derivative which can keep the L-ascorbic acid stable to heat and light and thus has a long shelf life, which is high in permeability into the skin, which can be quickly hydrolyzed by phosphatase, an enzyme that is ubiquitous in vivo, and which exhibits physiological activities that are inherent to L-ascorbic acid and beneficial to health, a method for producing such an L-ascorbic acid derivative, and a skin-whitening cosmetic material.There is provided an ascorbic acid derivative comprising an L-ascorbic acid-2-phosphate ester or a salt thereof wherein the phosphate ester has a branched alkyl group, the L-ascorbic acid-2-phosphate ester being of formula [13]. The ascorbic acid derivative is produced by a method comprising reacting a branched alkanol with phosphorus oxychloride to synthesize monoalkyldichlorophosphate or dialkylmonochlorophosphate, reacting the thus obtained substance with 5,6-O-isopropylidene-L-ascorbic acid obtained by reacting L-ascorbic acid with acetone, and subjecting the thus obtained substance to acid hydrolysis. There is also provided a cosmetic material containing such an ascorbic acid derivative by 0.05 to 80 percent by weight. (wherein each of R1 and R2 is a hydrogen (H) atom or an alkyl group having branches and including 3 to 30 carbon atoms, but not both of R1 and R2 are hydrogen (H) atoms)
    • 本发明的目的是提供一种L-抗坏血酸衍生物,其能够保持L-抗坏血酸对热和光的稳定性,因此具有长的保存期限,其对皮肤的渗透性高,可以通过磷酸酶快速水解, 在体内无处不在,表现出L-抗坏血酸固有的生理活性,有益健康的酶,生产这种L-抗坏血酸衍生物的方法,以及美白化妆品。 提供了包含L-抗坏血酸-2-磷酸酯或其盐的抗坏血酸衍生物,其中磷酸酯具有支链烷基,L-抗坏血酸-2-磷酸酯具有式[13]。 抗坏血酸衍生物是通过使支链烷醇与磷酰氯反应合成二烷基单磷酸二烷基酯和一氯二磷酸二烷基酯,使得到的物质与通过L-抗坏血酸与丙酮反应得到的5,6-O-异亚丙基-L-抗坏血酸 并将由此获得的物质进行酸水解。 还提供含有0.05〜80重量%的抗坏血酸衍生物的化妆品。 (其中R 1和R 2各自为氢(H)原子或具有分支且包含3至30个碳原子的烷基,但不是R' SUP> 1和R 2是氢(H)原子)
    • 50. 发明授权
    • Heating/cooling system
    • 加热/冷却系统
    • US07228700B2
    • 2007-06-12
    • US11055072
    • 2005-02-11
    • Kenzo MatsumotoYoshio WatabeHiroshi Nishikawa
    • Kenzo MatsumotoYoshio WatabeHiroshi Nishikawa
    • F25B15/00
    • F25D11/02F25B1/10F25B5/02F25B6/04F25B9/008F25B29/003F25B40/00F25B41/04F25B2309/061F25B2400/22F25D23/069
    • An object is to provide a heating/cooling system capable of achieving reduction of power consumption, and enhancement of performance in a heating/cooling system usable in such a manner as to be switched to be hot/cold. The heating/cooling system having a storage chamber usable in such a manner as to be switched to be hot/cold, comprises: a refrigerant circuit comprising a compressor, a gas cooler, a pressure reducing device, an evaporator and the like, containing carbon dioxide sealed as a refrigerant therein, and having a supercritical pressure on a high-pressure side; a radiator through which the refrigerant flowing out of the gas cooler flows before entering the pressure reducing device; and an air blower which sends air through the gas cooler, the inside of the storage chamber is heated by the radiator, the inside of the storage chamber is cooled by the evaporator, and the air blower is stopped in a case where the inside of the storage chamber is heated by the radiator.
    • 本发明的目的是提供一种能够实现能够降低功耗的加热/冷却系统,并且能够以能够切换为热/冷的方式使用的加热/冷却系统中的性能的提高。 具有可以切换为热/冷的方式使用的储存室的加热/冷却系统包括:制冷剂回路,包括压缩机,气体冷却器,减压装置,蒸发器等,其含有碳 二氧化碳作为制冷剂密封,在高压侧具有超临界压力; 在进入减压装置之前,从气体冷却器流出的制冷剂通过该散热器流动; 以及通过气体冷却器送风的鼓风机,储存室的内部由散热器加热,储存室的内部由蒸发器冷却,在鼓风机内部停止的情况下, 储存室由散热器加热。