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41. 外观设计

USD381281S Electric meter cover 失效
公开(公告)号：USD381281S
公开(公告)日：1997-07-22
申请号：US47289
申请日：1995-11-30
申请人： David J. Miller , Warren R. Germer , Raymond E. Fearnley , Rajiv D. Katwala
设计人： David J. Miller , Warren R. Germer , Raymond E. Fearnley , Rajiv D. Katwala

42. 发明授权

US5514959A Electric meter including a switch cover lockable in an open position 失效
标题翻译：电表包括可在闭合位置锁定的开关盖
公开(公告)号：US5514959A
公开(公告)日：1996-05-07
申请号：US364090
申请日：1994-12-27
申请人： Patrick J. Horan , Joseph R. Legere , David J. Miller
发明人： Patrick J. Horan , Joseph R. Legere , David J. Miller
IPC分类号： E05D11/10 , G01R11/02 , G01R11/24 , G01R1/00
CPC分类号： G01R11/02 , E05D11/105 , G01R22/066 , E05Y2900/20 , Y10T16/54028
摘要： An electric meter includes a housing, a switch positioned within an opening in the housing, a hinge pin having a first cross-sectional shape and being connected to the housing, and a switch cover having a passageway receiving the hinge pin therein and permitting pivotal movement of said switch cover between a closed position and an open position. The passageway has a second cross-sectional shape cooperating with the first cross-sectional shape of the hinge pin for locking the switch cover in the open position. The hinge pin preferably includes a generally cylindrical shaft and a ridge extending longitudinally thereon to define the first cross-sectional shape. Accordingly, the passageway of the switch cover is preferably defined by a generally cylindrical portion with a first longitudinally extending channel in communication therewith to define the second cross-sectional shape. The passageway may also include a second longitudinal channel cooperating with the ridge to lock the switch cover in the closed position.
摘要翻译：电表包括壳体，位于壳体内的开口内的开关，具有第一横截面形状并连接到壳体的铰链销，以及开关盖，其具有在其中容纳铰链销并允许枢转运动所述开关盖在关闭位置和打开位置之间。通道具有与铰链销的第一横截面形状配合的第二横截面形状，用于将开关盖锁定在打开位置。铰链销优选地包括大致圆柱形的轴和在其上纵向延伸以限定第一横截面形状的脊。因此，开关盖的通道优选地由具有与其连通的第一纵向延伸通道的大致圆柱形部分限定，以限定第二横截面形状。通道还可以包括与脊相配合的第二纵向通道，以将开关盖锁定在关闭位置。

43. 发明授权

US5505581A Loading and unloading system for motor vehicle transporter 失效
公开(公告)号：US5505581A
公开(公告)日：1996-04-09
申请号：US312401
申请日：1994-09-26
申请人： Peter Gearin , David J. Miller
发明人： Peter Gearin , David J. Miller
IPC分类号： B60P3/08
CPC分类号： B60P3/08
摘要： A system for loading motor vehicles onto, and unloading motor vehicles from, a transporting vehicle enables motor vehicles to be supported one above the other on a frame, after which the frame with its supported motor vehicles is moved as a unit onto a transporting vehicle at a loading location. After transport of the frame and its motor vehicles from the loading location to a destination, the motor vehicles are unloaded from the transporting vehicle not as a unit but rather individually while the frame remains on the transporting vehicle.

44. 发明授权

US5351805A Method and apparatus for unloading bulk materials 失效
标题翻译：卸载散装材料的方法和装置
公开(公告)号：US5351805A
公开(公告)日：1994-10-04
申请号：US129803
申请日：1993-09-30
申请人： David J. Miller , Allen R. Miller , Charles P. Miller
发明人： David J. Miller , Allen R. Miller , Charles P. Miller
IPC分类号： B65G53/48 , B65G65/16 , B65G67/62 , B65G33/32
CPC分类号： B65G65/22 , B65G53/48 , B65G67/606
摘要： An unloader for bulk materials is provided to transfer material such as cement from a barge or other bulk container. It includes a moveable and rotatable support member such as a crane or cantilevered arm that is adjacent the bulk container. A first conveyor or auger is connected to the support for pivotal movement and extends generally horizontally. A second conveyor or auger is connected to the distal end of the first conveyor for pivotal movement and is generally vertically oriented. A feeder unit is connected to the distal end of the second conveyor for universal and rotational movement. The feeder includes an uplift portion communicating with the second conveyor, the uplift portion advancing the bulk material at a rate slower than the second conveyor, and a collector portion communicating with the uplift portion. The collector portion includes converging auger assembly to advance the bulk material towards the uplift portion and to assist in transferring it into the uplift portion. The apparatus may further include a selectively operable energy responsive aeration system to inject air into the bulk material while it is being handled by the unloader, a scraper assembly attached to the feeder unit to assist in removing the last of the bulk material from its container, and a take-away assembly to transport the bulk material away from the unloader.
摘要翻译：提供用于散装材料的卸载机以从驳船或其他散装容器转移诸如水泥的材料。它包括可移动和可旋转的支撑构件，例如与散装容器相邻的起重机或悬臂。第一输送机或螺旋钻连接到支撑件以进行枢转运动，并且大体上水平地延伸。第二输送机或螺旋钻连接到第一输送机的远端，用于枢转运动，并且通常垂直定向。馈送单元连接到第二输送机的远端，用于通用和旋转运动。进料器包括与第二输送器连通的隆起部分，提升部分以比第二输送机慢的速率推进散装材料，以及与隆起部分连通的收集器部分。收集器部分包括会聚的螺旋推运器组件以将散装材料推向隆起部分并且帮助将其转移到隆起部分中。所述设备还可以包括选择性操作的能量响应式曝气系统，以便在其被卸载机处理时将空气注入到散装材料中;刮板组件，其附接到进料器单元以帮助从容器中去除最后的散装材料，以及将散装物料从卸载机运送出去的组件。

45. 发明授权

US4041623A Grade cutting machine 失效
标题翻译：等级切割机
公开(公告)号：US4041623A
公开(公告)日：1977-08-16
申请号：US615767
申请日：1975-09-22
申请人： David J. Miller , Charles P. Miller
发明人： David J. Miller , Charles P. Miller
IPC分类号： E02F3/78 , E01C23/12 , E02F3/76 , E02F3/84 , E02F7/04 , E02F5/00
CPC分类号： E01C19/008 , E01C23/088 , E02F3/7695 , E02F3/78 , E02F3/841 , Y10S37/907
摘要： A grade cutting machine having an elongated main frame supported on three bogey-mounted individually driven endless tracks. The cutting tool is rotatably mounted on an axis transverse the front of the main frame within an enclosing bowl. A vertically adjustable moldboard is provided across the back wall of the bowl behind the cutting tool. Two of the endless tracks are mounted on vertical non-rotatable axes on opposite sides of the main frame behind the moldboard and each is provided with an extensible frame-supporting member for automatic simultaneous or independent vertical adjustment. The third endless track which can control the steering under certain conditions is provided with an extensible frame-supporting member connected for independent manually controlled vertical adjustment. In one embodiment the drive means for the front pair of endless tracks are under the control of the steering function of the rear endless track so that, as a steering correction is made, the front endless track on the outside of the curve is driven faster while the front endless track on the inside of the curve is driven slower, the speed differences being inversely proportional to the radius of the curve being negotiated. A conveyor having a pivotal rear section under the control of dual rams through dual levers for deposit of the cuttings anywhere in a 180.degree. arc is provided. The moldboard is under the control of a pair of rams and carries both the grade sensor and the slope pendulum control whereby slope corrections are isolated from grade corrections.
摘要翻译：一种具有延长的主框架的等级切割机，支撑在三个独立驱动的环形履带上。切割工具可旋转地安装在横向包围碗内的主框架前部的轴上。在切割工具后面的碗的后壁上提供了可垂直调节的鞋面板。两个环形轨道安装在垂直不可旋转的轴上，位于模板的后面的主框架的相对侧上，并且每个设置有用于自动同时或独立的垂直调节的可延伸框架支撑构件。在一定条件下可以控制转向的第三条履带具有连接用于独立的手动控制垂直调节的可伸展的框架支撑件。在一个实施例中，用于前面一对环形轨道的驱动装置处于后部环形轨道的转向功能的控制之下，因此，作为转向校正，曲线外侧的前部循环轨道被更快地驱动，而曲线内侧的前面的无尽轨迹被驱动较慢，速度差与正在协商的曲线的半径成反比。提供了一种输送机，其具有通过双杆控制双重凸起的枢转后部分，用于在180度弧度的任何地方沉积切屑。刨花板处于一对公the的控制之下，同时承载坡度传感器和倾斜摆控制，从而将坡度修正与等级校正隔离开来。

46. 发明授权

US3999314A Small sub-grader 失效
标题翻译：小学生
公开(公告)号：US3999314A
公开(公告)日：1976-12-28
申请号：US629023
申请日：1975-11-05
申请人： David J. Miller , Charles P. Miller
发明人： David J. Miller , Charles P. Miller
IPC分类号： E01C19/22 , E01C23/00 , E02F3/76 , E02F3/84 , E02F3/85 , E02F5/00
CPC分类号： E02F3/783 , E02F3/78 , E02F3/841 , Y10S37/907
摘要： The rotating cutting tool of a sub-grader is adjustably mounted transverse the front of the frame of the machine upon a tool support in a manner which isolates changes in grade from changes in slope and which minimizes the influence of changes in slope upon the grade of the tool. The transverse pivot axis for grade control of the tool support is located at an intermediate point on the main frame, while the cutting tool, its associated drive means and housing are mounted on an independent pivot axis for slope control that extends longitudinally on one side of the main frame. Any changes made in the grade are accomplished by raising and lowering the entire tool support on the transverse axis equally at both ends which does not alter the slope of the tool. The arc of movement is relatively long so that the change in fore and aft altitude of the tool is minimal. The rotating tool is maintained perpendicular to and in the plane of its longitudinal slope control axis by the tool frame. However, any changes in slope are entirely independent of the grade deviations and the tool is maintained in a desired plane at all times.
摘要翻译：分级机的旋转切削工具可以横向机器框架的前部可调节地安装在工具支撑上，其方式是将坡度变化与坡度变化隔离，并使坡度变化对坡度变化的影响最小化工具。用于工具支撑件的坡度控制的横向枢转轴线位于主框架上的中间点处，而切割工具及其相关联的驱动装置和壳体安装在用于斜坡控制的独立枢转轴线上，用于在主框架。通过在两端均匀地升高和降低横向轴上的整个工具支架，而不会改变工具的斜率，可以实现任何改变。运动弧相对较长，使得工具的前后高度变化很小。旋转工具通过工具框架垂直于其纵向斜率控制轴线的平面保持。然而，斜率的任何变化完全独立于等级偏差，并且工具始终保持在所需的平面上。

47. 发明授权

US3981968A Solvent extraction of nickel from ammoniacal solutions 失效
标题翻译：从氨溶液中提取镍溶剂
公开(公告)号：US3981968A
公开(公告)日：1976-09-21
申请号：US487560
申请日：1974-07-11
申请人： David J. Miller , Tadeusz K. Wiewiorowski
发明人： David J. Miller , Tadeusz K. Wiewiorowski
IPC分类号： C22B23/00 , C01G51/10 , C22B3/30 , C22B3/36 , C01G53/00
CPC分类号： C22B23/04 , C22B3/0017 , C22B3/0037 , C22B3/0039 , Y02P10/234
摘要： An ammoniacal solution containing nickel and cobalt is contacted with an extractant comprising an oxime or oxine compound dissolved in an organic diluent to selectively extract the nickel into the organic phase while leaving most of the cobalt in the aqueous ammoniacal phase from which it is subsequently recovered. The nickel-loaded organic extract is washed with water and aqueous carbon dioxide to remove and recover ammonia which undesirably transfers to the organic phase during the extraction. The ammonia-free, nickel-loaded extract is then stripped with aqueous sulfuric acid at low temperature to remove the nickel. The ammonia-free nickel sulfate solution produced in the stripping operation is particularly suitable for recovering the nickel by electrolytic deposition. The stripped organic extract is further stripped with aqueous sulfuric acid at high temperature to remove and recover the small amount of cobalt which transfers to the organic phase during extraction and hampers reuse of the organic extractant in the process. Removal of the cobalt permits recycle of the extractant to the process.
摘要翻译：将含有镍和钴的氨溶液与溶解在有机稀释剂中的肟或氧化合物的萃取剂接触以选择性地将镍提取到有机相中，同时使大部分钴在其后续回收的氨水相中。将镍负载的有机萃取物用水和二氧化碳水溶液洗涤以除去并回收在萃取期间不期望地转移到有机相中的氨。然后将无氨，镍负载的萃取液在低温下用硫酸水溶液去除以除去镍。在剥离操作中产生的无氨硫酸镍溶液特别适用于通过电解沉积来回收镍。汽提的有机萃取液在高温下用硫酸水溶液进一步汽提，以除去和回收在萃取过程中转移到有机相中的少量钴，并阻碍了该方法中有机萃取剂的再利用。去除钴允许将萃取剂再循环到该方法中。

48. 发明申请

US20180086821A1 HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM 审中-公开
公开(公告)号：US20180086821A1
公开(公告)日：2018-03-29
申请号：US15629123
申请日：2017-06-21
申请人： Moses Rodriguez , David J. Miller , Larry R. Pease
发明人： Moses Rodriguez , David J. Miller , Larry R. Pease
IPC分类号： C07K16/18 , A61K38/00 , A61K39/00
CPC分类号： A61K38/00 , A61K2039/505 , C07K16/18 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/77 , C12Q1/6876 , Y02A50/473
摘要： Antibodies, particularly human antibodies, are disclosed having activity in treatment of demyelinating diseases and diseases of the central nervous system. Neuromodulatory agents are provided comprising a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, and active fragments, monomers and combinations thereof having one or more of the following characteristics: capable of inducing remyelination; binding to neural tissue; promoting Ca++ signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, and active fragments thereof. The invention extends to the use of antibodies and fragments in diagnostic and therapeutic applications, including screening assays.

49. 发明授权

US09701745B2 Human IgM antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system 有权
公开(公告)号：US09701745B2
公开(公告)日：2017-07-11
申请号：US14990325
申请日：2016-01-07
申请人： Moses Rodriguez , David J. Miller , Larry R. Pease
发明人： Moses Rodriguez , David J. Miller , Larry R. Pease
IPC分类号： C07K16/18 , C12Q1/68 , A61K38/00 , A61K39/00
CPC分类号： A61K38/00 , A61K2039/505 , C07K16/18 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/77 , C12Q1/6876 , Y02A50/473
摘要： Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of the central nervous system that are of viral, bacterial or idiopathic origin, including neural dysfunction caused by spinal cord injury. Neuromodulatory agents are set forth that include and comprise a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, a hapten, active fragments thereof, agonists thereof, mimics thereof, monomers thereof and combinations thereof. The neuromodulatory agent has one or more of the following characteristics: it is capable of inducing remyelination; binding to neural tissue; promoting Ca−− signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system of humans and domestic animals, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, active fragments thereof and the like. The invention also extends to the use of human antibodies, fragments, peptide derivatives and like materials, and their use in diagnostic and therapeutic applications, including screening assays for the discovery of additional antibodies that bind to cells of the nervous system, particularly oligodendrocytes.

50. 发明申请

US20160333078A1 HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM 有权
标题翻译：人IgM抗体，其特异性的诊断和治疗用途，特别是中枢神经系统
公开(公告)号：US20160333078A1
公开(公告)日：2016-11-17
申请号：US14990325
申请日：2016-01-07
申请人： Moses Rodriguez , David J. Miller , Larry R. Pease
发明人： Moses Rodriguez , David J. Miller , Larry R. Pease
IPC分类号： C07K16/18 , C12Q1/68
CPC分类号： A61K38/00 , A61K2039/505 , C07K16/18 , C07K2317/56 , C07K2317/565 , C07K2317/75 , C07K2317/77 , C12Q1/6876 , Y02A50/473
摘要： Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of the central nervous system that are of viral, bacterial or idiopathic origin, including neural dysfunction caused by spinal cord injury. Neuromodulatory agents are set forth that include and comprise a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, a hapten, active fragments thereof, agonists thereof, mimics thereof, monomers thereof and combinations thereof. The neuromodulatory agent has one or more of the following characteristics: it is capable of inducing remyelination; binding to neural tissue; promoting Ca−− signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system of humans and domestic animals, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, active fragments thereof and the like. The invention also extends to the use of human antibodies, fragments, peptide derivatives and like materials, and their use in diagnostic and therapeutic applications, including screening assays for the discovery of additional antibodies that bind to cells of the nervous system, particularly oligodendrocytes.
摘要翻译：公开了抗体，特别是人抗体，其表现出治疗脱髓鞘疾病以及中枢神经系统的病毒，细菌或特发性起源的其它疾病，包括由脊髓损伤引起的神经功能障碍的活性。阐述神经调节剂，其包括并且包含选自能够结合中枢神经系统结构或细胞的抗体，肽类似物，半抗原，其活性片段，其激动剂，其模拟物，其单体及其组合。神经调节剂具有以下一个或多个特征：它能够诱导髓鞘再生; 结合神经组织; 促进少突胶质细胞的Ca-信号传导; 并促进神经胶质细胞的细胞增殖。公开了示例性抗体的氨基酸和DNA序列。描述了使用多克隆IgM抗体和人单克隆抗体sHIgm22（LYM22），sHIgm46（LYM46）ebvHIgM MSI19D10，CB2bG8，AKJR4，CB2iE12，CB2iE7等治疗脱髓鞘疾病和人和家畜的中枢神经系统疾病的方法， MSI19E5和MSI10E10，其活性片段等。本发明还延伸到使用人类抗体，片段，肽衍生物和类似材料，以及它们在诊断和治疗应用中的用途，包括用于发现结合神经系统细胞，特别是少突胶质细胞的其它抗体的筛选测定。

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