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41. 发明授权

US10071528B2 Stiffened thin-walled fibre composite products and method of making same 有权
公开(公告)号：US10071528B2
公开(公告)日：2018-09-11
申请号：US13992382
申请日：2011-11-16
申请人： Christian Fischer , Julien Rion
发明人： Christian Fischer , Julien Rion
IPC分类号： B29C70/02 , B29K311/10 , B29D7/00 , B29D23/00 , B29C70/08 , B29C70/20 , B29C70/44 , B29D99/00
CPC分类号： B29C70/021 , B29C70/08 , B29C70/20 , B29C70/202 , B29C70/443 , B29D99/0014 , B29K2311/10 , Y10T428/1348 , Y10T428/24612
摘要： Stiffened thin-walled natural fiber composite product having first fiber yarns (A), each first fiber having a first thickness, and second fiber yarns (B) having a second thickness larger than the first thickness. At least one side of said product is even. Applications for a seat post; a bicycle saddle; a bicycle frame; a bicycle handle bar; a baseball bat; a piece of furniture; a paddle; or a sheet for automotive applications.

42. 发明授权

US09050941B2 Tensioning device for a safety belt 有权
标题翻译：安全带张紧装置
公开(公告)号：US09050941B2
公开(公告)日：2015-06-09
申请号：US13505164
申请日：2010-10-12
申请人： Christian Fischer , Martin Schmidt , Matthias Steinberg , Michael Pech , Tobias Voss , Thomas Schmidt , Simone Mesecke-Rischmann
发明人： Christian Fischer , Martin Schmidt , Matthias Steinberg , Michael Pech , Tobias Voss , Thomas Schmidt , Simone Mesecke-Rischmann
IPC分类号： B65H75/48 , B60R22/195 , B60R22/46
CPC分类号： B60R22/1954 , B60R22/4628 , B60R2022/4642
摘要： A tensioning device (10) for a seat belt, in particular in a motor vehicle, having a gas generator (17) and a piston (21) guided in a tube (16) that closes a pressure space (20) in the tube (16), whereas the pressure space (20) can be pressurized by the gas generator (17), as a result of which the piston (21) can be driven to perform a tensioning operation which can be transmitted to the seat belt by means of the force transmission means. The piston (21) having a closed or constricted opening (1, 1a), and the opening (1, 1a) can be enlarged and/or opened by the material erosion caused by the pressure and/or pressure conditions in the pressure space (20).
摘要翻译：一种用于安全带，特别是机动车辆的张紧装置（10），具有气体发生器（17）和引导管（16）的活塞（21），所述管子封闭管中的压力空间（20） 16），而压力空间（20）可以由气体发生器（17）加压，结果可以驱动活塞（21）进行张紧操作，该张紧操作可通过以下方式传递到安全带力传递装置。具有闭合或缩小的开口（1,1a）的活塞（21）和开口（1,1a）可以通过由压力空间中的压力和/或压力条件引起的材料侵蚀而被扩大和/或打开（ 20）。

43. 发明授权

US08895125B2 Multi-layer wood veneer moulding 有权
标题翻译：多层木皮单板成型
公开(公告)号：US08895125B2
公开(公告)日：2014-11-25
申请号：US13696828
申请日：2011-05-12
申请人： Christian Fischer , Sebastien Lavanchy , Thomas Wolf
发明人： Christian Fischer , Sebastien Lavanchy , Thomas Wolf
IPC分类号： B32B5/12 , B27D1/04 , B27D1/08 , B32B7/00 , B32B7/12 , B32B21/14
CPC分类号： B27D1/04 , B27D1/08 , B32B7/005 , B32B7/12 , B32B21/047 , B32B21/13 , B32B21/14 , B32B2255/08 , B32B2255/26 , B32B2266/0221 , B32B2266/0242 , B32B2266/0271 , B32B2266/0278 , B32B2266/0285 , B32B2307/72 , B32B2307/732 , Y10T156/1052 , Y10T428/16 , Y10T428/167 , Y10T428/24066
摘要： Multi-layer moulding having a high structural load-carrying capacity with two opposing broad faces and a laterally peripheral end face, containing, in layers, broad face on broad face, layered wood veneers and, lying between the wood veneers, adhesives. The wood veneers are layered in such a way that the grain of at least one of the wood veneers deviates from the grain of one or the other wood veneers by 45° to 90° and in that the grain of the wood veneers deviates by 22.5 to 67.5° with respect to a surface normal to an end face of the moulding.
摘要翻译：多层成型具有高的结构承载能力，具有两个相对的宽面和横向周向的端面，其包括宽面上的宽面，层状木单板，以及位于木材单板之间的粘合剂。木材单板以这样的方式分层，使得至少一个木材单板的颗粒从一个或另一个木材单板的颗粒偏离45°至90°，并且木材单板的颗粒偏离22.5° 相对于与模制品的端面垂直的表面为67.5°。

44. 发明授权

US08871796B2 Diaryl ether derivatives as notch sparing gamma secretase inhibitors 有权
标题翻译：二芳基醚衍生物作为缺口保留的γ分泌酶抑制剂
公开(公告)号：US08871796B2
公开(公告)日：2014-10-28
申请号：US13501628
申请日：2010-10-05
申请人： William Colby Brown , Jason Brubaker , Christian Fischer , Richard W. Heidebrecht , John T. Hendrix , Elizabeth H. Kelley , Rachel N. MacCoss , Joey L. Methot , Thomas Miller , Karin M. Otte , Phieng Siliphaivanh , Thomas Reger , Peter D. Williams , Catherine M. Wiscount
发明人： William Colby Brown , Jason Brubaker , Christian Fischer , Richard W. Heidebrecht , John T. Hendrix , Elizabeth H. Kelley , Rachel N. MacCoss , Joey L. Methot , Thomas Miller , Karin M. Otte , Phieng Siliphaivanh , Thomas Reger , Peter D. Williams , Catherine M. Wiscount
IPC分类号： A61K31/415 , C07D401/00 , C07D421/00 , C07D405/10 , C07D413/12 , C07D409/12 , C07D417/12 , C07D231/22 , C07D413/14 , C07D491/113 , C07D405/12 , C07D401/04 , C07D405/14 , C07D401/12
CPC分类号： C07D231/22 , C07D231/20 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D491/113
摘要： The invention encompasses a novel class of diaryl ether derivatives which inhibit the processing of APP by the putative γ-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included.
摘要翻译：本发明包括一类新的二芳基醚衍生物，其抑制通过推定的γ-分泌酶处理APP，同时保留Notch信号通路，因此可用于治疗或预防阿尔茨海默病而不发展Notch抑制介导的胃肠道问题。还包括药物组合物和使用方法。

45. 发明申请

US20130065013A1 MULTI-LAYER WOOD VENEER MOULDING 有权
标题翻译：多层木制模具
公开(公告)号：US20130065013A1
公开(公告)日：2013-03-14
申请号：US13696828
申请日：2011-05-12
申请人： Christian Fischer , Sebastien Lavanchy , Thomas Wolf
发明人： Christian Fischer , Sebastien Lavanchy , Thomas Wolf
IPC分类号： B32B5/12 , B32B38/00
CPC分类号： B27D1/04 , B27D1/08 , B32B7/005 , B32B7/12 , B32B21/047 , B32B21/13 , B32B21/14 , B32B2255/08 , B32B2255/26 , B32B2266/0221 , B32B2266/0242 , B32B2266/0271 , B32B2266/0278 , B32B2266/0285 , B32B2307/72 , B32B2307/732 , Y10T156/1052 , Y10T428/16 , Y10T428/167 , Y10T428/24066
摘要： Multi-layer moulding having a high structural load-carrying capacity with two opposing broad faces and a laterally peripheral end face, containing, in layers, broad face on broad face, layered wood veneers and, lying between the wood veneers, adhesives. The wood veneers are layered in such a way that the grain of at least one of the wood veneers deviates from the grain of one or the other wood veneers by 45° to 90° and in that the grain of the wood veneers deviates by 22.5 to 67.5° with respect to a surface normal to an end face of the moulding.
摘要翻译：多层成型具有高的结构承载能力，具有两个相对的宽面和横向周向的端面，其包括宽面上的宽面，层状木单板，以及位于木材单板之间的粘合剂。木材单板以这样的方式分层，使得至少一个木材单板的颗粒从一个或另一个木材单板的颗粒偏离45°至90°，并且木材单板的颗粒偏离22.5° 相对于与模制品的端面垂直的表面为67.5°。

46. 发明申请

US20130040933A1 AZAINDOLES AS JANUS KINASE INHIBITORS 审中-公开
标题翻译：作为JANUS KINASE INHIBITORS的AZAINDOLES
公开(公告)号：US20130040933A1
公开(公告)日：2013-02-14
申请号：US13643323
申请日：2011-04-21
申请人： Brandon Cash , Christian Fischer , Yudith Garcia , Joon Jung , Jason Katz , June Kim , Alexey Rivkin , Adam Schell , Tony Siu , David Witter , Hua Zhou
发明人： Brandon Cash , Christian Fischer , Yudith Garcia , Joon Jung , Jason Katz , June Kim , Alexey Rivkin , Adam Schell , Tony Siu , David Witter , Hua Zhou
IPC分类号： A61K31/497 , C07D519/00 , A61K31/5377 , A61K31/541 , A61K31/4985 , A61P35/00 , A61P11/06 , A61P37/00 , A61P1/04 , A61P25/00 , A61P3/10 , C07D471/04 , A61P19/02
CPC分类号： C07D471/04 , C07D519/00
摘要： The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof. Compounds of formula I are inhibitors of Janus kinases and as such are useful for the treatment of various diseases and conditions mediated by said enzymes, such as rheumatoid arthritis, asthma, COPD, ALS, and the like.
摘要翻译：本发明提供式I化合物或其药学上可接受的盐。式I化合物是Janus激酶的抑制剂，因此可用于治疗由所述酶介导的各种疾病和病症，例如类风湿性关节炎，哮喘，COPD，ALS等。

47. 发明申请

US20120247946A1 MONOLITHIC PHOTOCATALYST SYSTEM FOR GENERATING ELECTRICITY 审中-公开
标题翻译：用于生成电力的单片光电子系统
公开(公告)号：US20120247946A1
公开(公告)日：2012-10-04
申请号：US13389397
申请日：2010-08-09
申请人： Sigrid Obenland , Christian Fischer , Harald Natter
发明人： Sigrid Obenland , Christian Fischer , Harald Natter
IPC分类号： B01J19/12 , C01B3/04 , C01B13/02
CPC分类号： C01B3/042 , B01J23/888 , B01J27/045 , B01J31/1815 , B01J35/004 , B01J35/04 , B01J2231/62 , B01J2231/70 , B01J2531/821 , C01B13/0207 , C25B1/003 , Y02E60/364 , Y02E60/368
摘要： Described is a monolithic catalyst system (1) for the cleavage of water into hydrogen and oxygen with the aid of light, comprising a first photoactive material (50) capable by itself or together with one or more auxiliary catalysts when irradiated with light having a wavelength ≧420 nm of generating oxygen and protons from water, and a second photoactive material (60) capable by itself or together one or more auxiliary catalysts (92) when irradiated with light having a wavelength ≧420 nm of reducing protons in water to hydrogen, the first photoactive material (50) and second photoactive material (60) being in electrical contact via one or more electron-conducting materials (30, 20, 40, 60a) the system being in that characterized in that a load or an electric consumer is interposed in between at least one electron-conducting material. Likewise described is a method of generating oxygen, hydrogen and electricity from water using the catalyst system.
摘要翻译：描述了一种用于借助于光将水裂解成氢和氧的整体式催化剂体系（1），其包括当用具有波长的光照射时本身或与一种或多种辅助催化剂一起使用的第一光活性材料（50）当波长≥420nm的光被水中的还原质子照射到氢时，能够自身或一个或多个辅助催化剂（92）产生的能量的第二光活性材料（60）所述第一光活性材料（50）和所述第二光敏材料（60）经由一个或多个电子传导材料（30,20,40,60a）电接触，所述系统的特征在于负载或电消费者是介于至少一种电子传导材料之间。同样地描述了使用催化剂体系从水产生氧气，氢气和电力的方法。

48. 发明申请

US20110313001A1 TRIAZOLE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE 审中-公开
标题翻译：用于治疗阿尔茨海默病的三唑衍生物
公开(公告)号：US20110313001A1
公开(公告)日：2011-12-22
申请号：US13133833
申请日：2009-12-07
申请人： Christian Fischer , Adam J. Schell , Benito Munoz
发明人： Christian Fischer , Adam J. Schell , Benito Munoz
IPC分类号： A61K31/4439 , A61P25/28 , C07D403/10 , A61K31/4192 , C07D401/10 , C07D413/14
CPC分类号： C07D403/10 , C07D401/10
摘要： According to the invention there is provided a compound of formula (I): (I) or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of Aβ42 and hence are useful in treatment of Alzheimer's disease and related conditions.
摘要翻译：根据本发明，提供式（I）化合物：（I）或其药学上可接受的盐或水合物; 其中变量如本文所定义。这些化合物选择性地减弱A＆bgr的产生42，因此可用于治疗阿尔茨海默病和相关病症。

49. 发明申请

US20100222320A1 TRIAZOLE DERIVATIVES FOR TREATING ALZHEIMER'S DISEASE AND RELATED CONDITIONS 失效
标题翻译：治疗阿尔茨海默病的三唑衍生物及相关条件
公开(公告)号：US20100222320A1
公开(公告)日：2010-09-02
申请号：US12663432
申请日：2008-06-09
申请人： Christian Fischer , Ben Munoz , Susan Zultanski , Joey Methot , Hua Zhou , W. Colby Brown
发明人： Christian Fischer , Ben Munoz , Susan Zultanski , Joey Methot , Hua Zhou , W. Colby Brown
IPC分类号： A61K31/337 , C07D403/10 , A61K31/4192 , C07D403/14 , A61K31/55 , C07D487/04 , C07D413/14 , A61K31/5377 , C07D205/04 , A61P25/28
CPC分类号： C07D403/10 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D455/04 , C07D471/04 , C07D487/04 , C07D487/06 , C07D491/048 , C07D495/04 , C07D513/04
摘要： Compounds of formula I: Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain, in particular Alzheimer's disease.
摘要翻译：式I化合物：选择性减弱A＆Bgr的产生（1-42），因此可用于治疗或预防与A＆Bgr沉积相关的疾病; 在大脑中，特别是阿尔茨海默病。

50. 发明授权

US06371069B1 Intake device 失效
标题翻译：进气装置
公开(公告)号：US06371069B1
公开(公告)日：2002-04-16
申请号：US09684956
申请日：2000-10-05
申请人： Christian Fischer
发明人： Christian Fischer
IPC分类号： F02N3510
CPC分类号： F02M35/10124 , F02B27/0215 , F02B27/0236 , F02M35/10052 , F02M35/10065 , F02M35/10072 , F02M35/10118 , F02M35/10301 , F02M35/10321 , F02M35/10347 , F02M35/1036 , F02M35/104 , Y02T10/146
摘要： An air intake device (10) especially adapted for use with an internal combustion engine, which achieves longer air intake tubes using a very simple geometry and which directly guides aspirated air without sharp deflections. The air intake device comprises a manifold (11), intake tubes (12), and an adjusting unit (13). The manifold (11) and the adjusting unit (13) form air intake channels (14), each leading into an air intake tube. The air intake channels (14) are arranged in a “cloverleaf” about the adjusting unit (13). To achieve an optimum charging of the cylinders of an internal combustion engine in all speed ranges, the adjusting unit (13) is steplessly or continuously adjustable. To establish preferred settings, rotary or sliding sleeves with interruptions can be integrated into the air intake device.
摘要翻译：一种特别适于与内燃机一起使用的进气装置（10），其使用非常简单的几何形状实现更长的进气管，并且直接引导吸气空气而没有尖锐的偏转。进气装置包括歧管（11），进气管（12）和调节单元（13）。歧管（11）和调节单元（13）形成进气通道（14），每个通道进入进气管。进气通道（14）围绕调节单元（13）布置在“三叶草”中。为了在所有速度范围内实现内燃机的气缸的最佳充气，调节单元（13）是无级或连续可调的。为了建立优先设置，可以将具有中断的旋转或滑动套筒集成到进气装置中。

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