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41. 发明申请

US20120077190A1 SUBSTRATES, SYSTEMS AND METHODS FOR ANALYZING MATERIALS 有权
标题翻译：用于分析材料的基板，系统和方法
公开(公告)号：US20120077190A1
公开(公告)日：2012-03-29
申请号：US13245578
申请日：2011-09-26
申请人： Paul Lundquist , Stephen Turner
发明人： Paul Lundquist , Stephen Turner
IPC分类号： C12Q1/68 , G01N21/64 , C12M1/40
CPC分类号： C12Q1/6874 , B01L2300/0636 , C12Q1/6869 , G01N21/64 , G01N21/6428 , G01N21/645 , G01N21/6452 , G01N21/648 , G01N21/7703 , G01N21/7743 , G01N2021/6439 , G01N2021/7786 , G01N2201/08 , G02B6/10 , G02B6/43
摘要： Substrates, systems and methods for analyzing materials that include waveguide arrays disposed upon or within the substrate such that evanescent fields emanating from the waveguides illuminate materials disposed upon or proximal to the surface of the substrate, permitting analysis of such materials. The substrates, systems and methods are used in a variety of analytical operations, including, inter alia, nucleic acid analysis, including hybridization and sequencing analyses, cellular analyses and other molecular analyses.
摘要翻译：用于分析材料的衬底，系统和方法，其包括设置在衬底上或衬底内的波导阵列，使得从波导发出的消逝场照射设置在衬底表面上或其附近的材料，从而允许分析这些材料。底物，系统和方法用于各种分析操作，包括核酸分析，包括杂交和测序分析，细胞分析和其他分子分析。

42. 发明授权

US07903698B1 Controlled optical filament generation and energy propagation 有权
标题翻译：受控的光纤丝生成和能量传播
公开(公告)号：US07903698B1
公开(公告)日：2011-03-08
申请号：US11357701
申请日：2006-02-17
申请人： Paul Lundquist , Stephen William McCahon
发明人： Paul Lundquist , Stephen William McCahon
IPC分类号： H01S3/10
CPC分类号： G02F1/3511 , G01S7/484
摘要： Systems and methods herein provide for the controlled formation of plasma filaments. For example, a system that radiates energy through a gas includes a laser that generates a laser pulse, and an optical element with which the laser propagates the laser pulse to control placement of an optical filament within a beam cross-section of the laser pulse. The optical filament may thereby generate a plasma filament, which may propagate energy. In this regard, an energy source may provide energy such that the plasma filament directs propagation of the energy for delivery to an application. The energy may be electrical energy, electromagnetic energy, optical energy, or a combination thereof. Generally, the optical element may impart at least one phase singularity within the laser pulse. Alternatively or additionally, the optical element may include at least one optical inhomogeneity.
摘要翻译：本文的系统和方法提供等离子体细丝的受控形成。例如，通过气体辐射能量的系统包括产生激光脉冲的激光器和激光器传播激光脉冲以控制光纤在激光脉冲的光束横截面内的放置的光学元件。因此，光纤丝可能产生可能传播能量的等离子体灯丝。在这方面，能量源可以提供能量，使得等离子体细丝将能量的传播引导到应用。能量可以是电能，电磁能，光能或其组合。通常，光学元件可以在激光脉冲内赋予至少一个相位奇点。或者或另外，光学元件可以包括至少一个光学不均匀性。

43. 发明申请

US20090303576A1 TRANSIENT OPTICAL POWER SUPPRESSING APPARATUS, METHOD, AND NETWORK 有权
标题翻译：瞬态光电抑制装置，方法和网络
公开(公告)号：US20090303576A1
公开(公告)日：2009-12-10
申请号：US12174395
申请日：2008-07-16
申请人： Paul Lundquist , Marc Levesque , Denis Zaccarin
发明人： Paul Lundquist , Marc Levesque , Denis Zaccarin
IPC分类号： H01S3/00
CPC分类号： H04B10/296 , H01S5/042 , H01S5/06825
摘要： An apparatus for suppressing optical power transients includes a variable optical attenuator receiving an input optical signal and outputting an output optical signal; an optical power sensing element coupled to the input optical signal and sensing a portion of the input optical signal; and a feedforward loop controller coupled to the variable optical attenuator and to the optical power sensing element; the feedforward control loop providing feedforward control of the variable optical attenuator to reduce optical power transients of the input optical signal and maintain a substantially constant output power based on the input optical power and a reference value; the variable optical attenuator having a default opaque state in which the input optical signal is substantially attenuated when power is not being supplied to said variable optical attenuator. Variations include feedback loop controllers and a combination feedback and feedforward loop controllers.
摘要翻译：用于抑制光功率瞬变的装置包括：可变光衰减器，其接收输入光信号并输出输出光信号; 耦合到所述输入光信号并感测所述输入光信号的一部分的光功率感测元件; 以及耦合到所述可变光衰减器和所述光功率感测元件的前馈环路控制器; 所述前馈控制环路提供所述可变光衰减器的前馈控制以减少所述输入光信号的光功率瞬变，并且基于所述输入光功率和参考值保持基本恒定的输出功率; 所述可变光衰减器具有默认不透明状态，其中当功率未被提供给所述可变光衰减器时，所述输入光信号基本衰减。变化包括反馈回路控制器和组合反馈和前馈回路控制器。

44. 发明授权

US07589889B2 Transient optical power suppressing apparatus, method, and network 有权
公开(公告)号：US07589889B2
公开(公告)日：2009-09-15
申请号：US12174351
申请日：2008-07-16
申请人： Paul Lundquist , Marc Levesque , Denis Zaccarin
发明人： Paul Lundquist , Marc Levesque , Denis Zaccarin
IPC分类号： H04B10/17 , G02B6/26
CPC分类号： H04B10/296 , H01S5/042 , H01S5/06825
摘要： An apparatus for suppressing optical power transients includes a variable optical attenuator receiving an input optical signal and outputting an output optical signal; an optical power sensing element coupled to the input optical signal and sensing a portion of the input optical signal; and a feedforward loop controller coupled to the variable optical attenuator and to the optical power sensing element; the feedforward control loop providing feedforward control of the variable optical attenuator to reduce optical power transients of the input optical signal and maintain a substantially constant output power based on the input optical power and a reference value; the variable optical attenuator having a default opaque state in which the input optical signal is substantially attenuated when power is not being supplied to said variable optical attenuator. Variations include feedback loop controllers and a combination feedback and feedforward loop controllers.

45. 发明授权

US07483205B1 Transient optical power suppressing apparatus, method, and network 有权
标题翻译：瞬态光功率抑制装置，方法和网络
公开(公告)号：US07483205B1
公开(公告)日：2009-01-27
申请号：US10855385
申请日：2004-05-28
申请人： Paul Lundquist , Marc Levesque , Denis Zaccarin
发明人： Paul Lundquist , Marc Levesque , Denis Zaccarin
IPC分类号： H04B10/17 , G02B6/26
CPC分类号： H04B10/296 , H01S5/042 , H01S5/06825
摘要： An apparatus for suppressing optical power transients includes a variable optical attenuator receiving an input optical signal and outputting an output optical signal; an optical power sensing element coupled to the input optical signal and sensing a portion of the input optical signal; and a feedforward loop controller coupled to the variable optical attenuator and to the optical power sensing element; the feedforward control loop providing feedforward control of the variable optical attenuator to reduce optical power transients of the input optical signal and maintain a substantially constant output power based on the input optical power and a reference value; the variable optical attenuator having a default opaque state in which the input optical signal is substantially attenuated when power is not being supplied to said variable optical attenuator. Variations include feedback loop controllers and a combination feedback and feedforward loop controllers.
摘要翻译：用于抑制光功率瞬变的装置包括：可变光衰减器，其接收输入光信号并输出输出光信号; 耦合到所述输入光信号并感测所述输入光信号的一部分的光功率感测元件; 以及耦合到所述可变光衰减器和所述光功率感测元件的前馈环路控制器; 所述前馈控制环路提供所述可变光衰减器的前馈控制以减少所述输入光信号的光功率瞬变，并且基于所述输入光功率和参考值保持基本恒定的输出功率; 所述可变光衰减器具有默认不透明状态，其中当功率未被提供给所述可变光衰减器时，所述输入光信号基本衰减。变化包括反馈回路控制器和组合反馈和前馈回路控制器。

46. 发明申请

US20080157005A1 Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources 有权
公开(公告)号：US20080157005A1
公开(公告)日：2008-07-03
申请号：US11978211
申请日：2007-10-26
申请人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
发明人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
IPC分类号： A61N5/00
CPC分类号： G01J3/02 , G01J3/0224 , G01J3/10 , G01J3/14 , G01J3/2803 , G01N21/6445 , G01N21/6452 , G01N21/6456 , G01N21/648 , G01N2021/6417
摘要： Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.

47. 发明申请

US20080152280A1 Substrates, systems and methods for analyzing materials 有权
公开(公告)号：US20080152280A1
公开(公告)日：2008-06-26
申请号：US11981796
申请日：2007-10-31
申请人： Paul Lundquist , Stephen Turner
发明人： Paul Lundquist , Stephen Turner
IPC分类号： G02B6/26
CPC分类号： G01N21/648 , G01N21/6428 , G01N21/6452 , G01N21/7703 , G01N2021/7786 , G02B6/43
摘要： Substrates, systems and methods for analyzing materials that include waveguide arrays disposed upon or within the substrate such that evanescent fields emanating from the waveguides illuminate materials disposed upon or proximal to the surface of the substrate, permitting analysis of such materials. The substrates, systems and methods are used in a variety of analytical operations, including, inter alia, nucleic acid analysis, including hybridization and sequencing analyses, cellular analyses and other molecular analyses.

48. 发明授权

US08149399B2 Methods and systems for simultaneous real-time monitoring of optical signals from multiple sources 有权
公开(公告)号：US08149399B2
公开(公告)日：2012-04-03
申请号：US13103278
申请日：2011-05-09
申请人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
发明人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
IPC分类号： G01J3/30
CPC分类号： G01J3/02 , G01J3/0224 , G01J3/10 , G01J3/14 , G01J3/2803 , G01N21/6445 , G01N21/6452 , G01N21/6456 , G01N21/648 , G01N2021/6417
摘要： Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.

49. 发明申请

US20110287981A1 METHODS AND SYSTEMS FOR SIMULTANEOUS REAL-TIME MONITORING OF OPTICAL SIGNALS FROM MULTIPLE SOURCES 有权
公开(公告)号：US20110287981A1
公开(公告)日：2011-11-24
申请号：US13103278
申请日：2011-05-09
申请人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
发明人： Paul Lundquist , Denis Zaccarin , Yves Lacroix , Stephen Turner , John Dixon
IPC分类号： C40B60/12
CPC分类号： G01J3/02 , G01J3/0224 , G01J3/10 , G01J3/14 , G01J3/2803 , G01N21/6445 , G01N21/6452 , G01N21/6456 , G01N21/648 , G01N2021/6417
摘要： Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.

50. 发明授权

US07820983B2 Substrates, systems and methods for analyzing materials 有权
标题翻译：基材，分析材料的系统和方法
公开(公告)号：US07820983B2
公开(公告)日：2010-10-26
申请号：US11849157
申请日：2007-08-31
申请人： Paul Lundquist , Stephen Turner
发明人： Paul Lundquist , Stephen Turner
IPC分类号： G01N21/64
CPC分类号： G01N21/648 , G01N21/6428 , G01N21/6452 , G01N21/7703 , G01N2021/7786 , G02B6/43
摘要： Substrates, systems and methods for analyzing materials that include waveguide arrays disposed upon or within the substrate such that evanescent fields emanating from the waveguides illuminate materials disposed upon or proximal to the surface of the substrate, permitting analysis of such materials. The substrates, systems and methods are used in a variety of analytical operations, including, inter alia, nucleic acid analysis, including hybridization and sequencing analyzes, cellular analyzes and other molecular analyzes.
摘要翻译：用于分析材料的衬底，系统和方法，其包括设置在衬底上或衬底内的波导阵列，使得从波导发出的消逝场照射设置在衬底表面上或其附近的材料，从而允许分析这些材料。底物，系统和方法用于各种分析操作，包括核酸分析，包括杂交和测序分析，细胞分析和其他分子分析。

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