专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

41. 发明申请

US20120303292A1 Binding Affinity Scoring With Penalty For Breaking Conjugation Between Aromatic Ligand Groups 有权
标题翻译：用于打破芳族配位体之间的共轭的结合亲和力评分
公开(公告)号：US20120303292A1
公开(公告)日：2012-11-29
申请号：US13113506
申请日：2011-05-23
申请人： Richard A. Friesner , Robert Murphy
发明人： Richard A. Friesner , Robert Murphy
IPC分类号： G06F19/00
CPC分类号： G06F19/706
摘要： A method of scoring binding affinity of a proposed ligand molecule for a receptor molecule using computer analysis and computer data bases to accounts for the increase in energy required where docking disrupts or partially disrupts the π-conjugated character of the ligand when bound to the receptor. The method uses data representing one or more proposed ligand molecules to be scored and data representing the receptor molecule. Computer analysis of the proposed ligand molecule data determines whether the ligand includes at least one π-conjugated moiety having multiple possible geometries, one of those geometries being characterized by less delocalization of electrons across the π-conjugated moiety than the delocalization of electrons characterizing another of those geometries. Computer analysis of the predicted ligand-receptor structure determines whether the ligand in the ligand-receptor structure adopts the geometry characterized by less delocalization. If so, a penalty is explicitly imposed for reduced delocalization of electrons across the π-conjugated moieties.
摘要翻译：使用计算机分析和计算机数据库对拟议的配体分子对受体分子的结合亲和力进行评估的方法，以考虑到所需能量的增加所需的能量的增加，其中对接在与受体结合时破坏或部分地破坏配体的共轭特征。该方法使用表示一个或多个所提出的配体分子得分的数据和表示受体分子的数据。所提出的配体分子数据的计算机分析确定配体是否包括具有多个可能几何形状的至少一个共轭部分，其中一个几何的特征在于电子跨越π-共轭部分的离域远离局部化另一个这些几何。预测的配体 - 受体结构的计算机分析确定配体 - 受体结构中的配体是否采用以较少离域为特征的几何。如果是这样的话，明确规定减少电子跨越π-共轭部分的局域化的惩罚。

42. 发明申请

US20120252683A1 Binding Affinity Scoring Function Penalizing Compounds Which Make Unfavorable Hydrophobic Contacts With Localized Water Molecules In The Receptor Active Site 有权
标题翻译：结合亲和力评分功能处罚化合物，其与受体活性位点中的局部水分子形成不利的疏水接触
公开(公告)号：US20120252683A1
公开(公告)日：2012-10-04
申请号：US13079725
申请日：2011-04-04
申请人： Richard A. Friesner , Robert Murphy
发明人： Richard A. Friesner , Robert Murphy
IPC分类号： C40B30/02
CPC分类号： G06F19/706 , G06F19/16
摘要： A method of scoring binding affinity of a proposed ligand molecule for a receptor molecule using a computer and computer data bases, which accounts for the increase in energy required where docking disrupts water molecules that are localized at ligand hydration sites. The method uses computer-stored data representing a predicted ligand-receptor structure (preferably one that is validated). The computerized scoring analysis includes determining whether the receptor includes one or more hydration sites occupied by localized water, and, if so, assessing a penalty if docking the ligand into the receptor results in unfavorable interaction of the ligand with a localized water molecule remaining at the receptor hydration site (i.e. after docking).
摘要翻译：使用计算机和计算机数据库对拟议的配体分子对受体分子的结合亲和力进行评分的方法，其考虑到对接破坏位于配体水合位点的水分子所需的能量的增加。该方法使用表示预测的配体 - 受体结构的计算机存储的数据（优选被验证的数据）。计算机化评分分析包括确定受体是否包含被局部水占据的一个或多个水合位点，如果是，则将配体对接到受体中来评估惩罚，导致配体与保留在该位点处的局部水分子的不利相互作用受体水合位点（即对接后）。

43. 发明授权

US08247255B2 Modular system and process for continuous deposition of a thin film layer on a substrate 有权
标题翻译：用于在衬底上连续沉积薄膜层的模块化系统和工艺
公开(公告)号：US08247255B2
公开(公告)日：2012-08-21
申请号：US12638653
申请日：2009-12-15
申请人： Mark Jeffrey Pavol , Russell Weldon Black , Brian Robert Murphy , Christopher Rathweg , Edwin Jackson Little , Max William Reed
发明人： Mark Jeffrey Pavol , Russell Weldon Black , Brian Robert Murphy , Christopher Rathweg , Edwin Jackson Little , Max William Reed
IPC分类号： H01L21/00
CPC分类号： C23C14/568
摘要： A process and associated system for vapor deposition of a thin film layer on a photovoltaic (PV) module substrate is includes establishing a vacuum chamber and introducing the substrates individually into the vacuum chamber. The substrates are pre-heated as they are conveyed through the vacuum chamber, and are then conveyed in serial arrangement through a vapor deposition apparatus in the vacuum chamber wherein a thin film of a sublimed source material is deposited onto an upper surface of the substrates. The substrates are conveyed through the vapor deposition apparatus at a controlled constant linear speed such that leading and trailing sections of the substrate in a conveyance direction are exposed to the same vapor deposition conditions within the vapor deposition apparatus. The vapor deposition apparatus may be supplied with source material in a manner so as not to interrupt the vapor deposition process or non-stop conveyance of the substrates through the vapor deposition apparatus.
摘要翻译：用于在光伏（PV）模块衬底上蒸镀薄膜层的工艺和相关系统包括建立真空室并将衬底单独地引入真空室中。衬底在被输送通过真空室时被预热，然后通过真空室中的气相沉积设备以串联方式输送，其中将升华的源材料的薄膜沉积在衬底的上表面上。基板以受控的恒定线速度传送通过蒸镀装置，使得基板的输送方向的前段和后段在气相沉积装置内暴露于相同的气相沉积条件。可以以不中断气相沉积处理或通过气相沉积设备不间断地输送基板的方式向气相沉积设备供应源材料。

44. 发明授权

US08151633B2 Methods and systems for characterizing LCM particle plugging and rheology in real time 有权
标题翻译：实时表征LCM颗粒堵塞和流变学的方法和系统
公开(公告)号：US08151633B2
公开(公告)日：2012-04-10
申请号：US12328836
申请日：2008-12-05
申请人： Dale Jamison , Robert Murphy , J. G. Savins
发明人： Dale Jamison , Robert Murphy , J. G. Savins
IPC分类号： G01N11/04
CPC分类号： G01N33/2823 , E21B21/003 , G01N11/04
摘要： Methods and systems for characterizing drilling fluids laden with LCM (Lost Circulation Material) and other solid materials are disclosed. A test cell for analyzing a fluid is provided with a first conical inner portion and an axial positioning device positioned along an axis of the test cell. A first conical plug is coupled to the axial positioning device and is movable in and out of the first conical inner portion along the axis of the test cell. A fluid inlet is positioned at a first location on the test cell and a fluid outlet at a second location.
摘要翻译：公开了用LCM（失物循环材料）和其他固体材料表征钻井液的方法和系统。用于分析流体的测试单元设置有沿着测试单元的轴线定位的第一锥形内部部分和轴向定位装置。第一锥形塞被联接到轴向定位装置，并且可沿着测试电池的轴线移动进出第一锥形内部部分。流体入口位于测试电池的第一位置，在第二位置处设有流体出口。

45. 发明申请

US20110263070A1 TREATMENT OF THIN FILM LAYERS PHOTOVOLTAIC MODULE MANUFACTURE 有权
标题翻译：薄膜层的处理光伏组件制造
公开(公告)号：US20110263070A1
公开(公告)日：2011-10-27
申请号：US12766135
申请日：2010-04-23
申请人： Cory Allen Schaeffer , Brian Robert Murphy
发明人： Cory Allen Schaeffer , Brian Robert Murphy
IPC分类号： H01L31/18 , H01L21/06
CPC分类号： H01L21/6715 , H01L21/67706 , H01L31/0296 , H01L31/073 , H01L31/206 , Y02E10/543 , Y02P70/521
摘要： Systems and processes for treatment of a cadmium telluride thin film photovoltaic device are generally provided. The systems can include a treatment system and a conveyor system. The treatment system includes a preheating section, a treatment chamber, and an anneal oven that are integrally interconnected within the treatment system. The conveyor system is operably disposed within the treatment system and configured for transporting substrates in a serial arrangement into and through the preheat section, into and through the treatment chamber, and into and through the anneal oven at a controlled speed. The treatment chamber is configured for applying a material to a thin film on a surface of the substrate and the anneal oven is configured to heat the substrate to an annealing temperature as the substrates are continuously conveyed by the conveyor system through the treatment chamber.
摘要翻译：通常提供用于处理碲化镉薄膜光伏器件的系统和方法。系统可以包括处理系统和输送系统。处理系统包括在处理系统内整体互连的预热段，处理室和退火炉。输送系统可操作地设置在处理系统内并且被配置用于将串联装置中的基板输送并通过预热部分进入和通过处理室，并以受控的速度进入和通过退火炉。处理室被配置为将材料施加到基板的表面上的薄膜上，并且退火炉被构造成当基板被输送系统通过处理室连续输送时，将基板加热到退火温度。

46. 发明申请

US20100139387A1 Methods and Systems for Characterizing LCM Particle Plugging and Rheology in Real Time 有权
标题翻译：实时表征LCM颗粒堵塞和流变学的方法和系统
公开(公告)号：US20100139387A1
公开(公告)日：2010-06-10
申请号：US12328836
申请日：2008-12-05
申请人： Dale E. Jamison , Robert Murphy , J.G. Savins
发明人： Dale E. Jamison , Robert Murphy , J.G. Savins
IPC分类号： E21B49/10
CPC分类号： G01N33/2823 , E21B21/003 , G01N11/04
摘要： Methods and systems for characterizing drilling fluids laden with LCM (Lost Circulation Material) and other solid materials are disclosed. A test cell for analyzing a fluid is provided with a first conical inner portion and an axial positioning device positioned along an axis of the test cell. A first conical plug is coupled to the axial positioning device and is movable in and out of the first conical inner portion along the axis of the test cell. A fluid inlet is positioned at a first location on the test cell and a fluid outlet at a second location.
摘要翻译：公开了用LCM（失物循环材料）和其他固体材料表征钻井液的方法和系统。用于分析流体的测试单元设置有沿着测试单元的轴线定位的第一锥形内部部分和轴向定位装置。第一锥形塞被联接到轴向定位装置，并且可沿着测试电池的轴线移动进出第一锥形内部部分。流体入口位于测试电池的第一位置，在第二位置处设有流体出口。

47. 发明授权

US07407227B1 Headrest having an integrated video screen 有权
标题翻译：头枕具有集成的视频屏幕
公开(公告)号：US07407227B1
公开(公告)日：2008-08-05
申请号：US11415696
申请日：2006-05-02
申请人： Eugene M. Tuccinardi , Ernesto R. Haack , Robert Murphy , Frank Barrese , Roel C. Espina , Jon A. Molo , Theo Zoetemelk
发明人： Eugene M. Tuccinardi , Ernesto R. Haack , Robert Murphy , Frank Barrese , Roel C. Espina , Jon A. Molo , Theo Zoetemelk
IPC分类号： A47C7/62
CPC分类号： B60R11/0235 , B60N2/879
摘要： A seat back video display assembly adapted to be positioned in the back of a vehicle seat having an outer skin cover. In one aspect, the assembly may comprise a receptacle member having sidewalls and a back wall so as to define an opening wherein the receptacle member is adapted to be positioned in the back of the vehicle seat. In addition, the assembly may further comprise a carrier member having sidewalls and a back wall so as to define an opening, wherein the carrier member includes at least one fastener that extends from the back wall of the carrier member and engages with the back wall of the receptacle member to secure the carrier member into the receptacle member. Moreover, the assembly may still further comprise a video display unit that is sized so as to be positioned secured within the opening in the carrier member, wherein the video display unit provides video signals.
摘要翻译：一种座椅靠背视频显示组件，其适于定位在具有外护罩的车辆座椅的后部。在一个方面，组件可以包括具有侧壁和后壁以便限定开口的容器构件，其中容器构件适于定位在车辆座椅的后部。此外，组件还可以包括具有侧壁和后壁以便限定开口的承载构件，其中承载构件包括至少一个紧固件，该紧固件从承载构件的后壁延伸并与所述容器构件将所述承载构件固定到所述容器构件中。此外，组件还可以包括视频显示单元，其尺寸设计成被固定在承载构件中的开口内，其中视频显示单元提供视频信号。

48. 发明授权

US07395324B1 Method and apparatus for maintaining a computer system 有权
标题翻译：用于维护计算机系统的方法和装置
公开(公告)号：US07395324B1
公开(公告)日：2008-07-01
申请号：US09606786
申请日：2000-06-28
申请人： Robert Murphy , Andrew Woodward
发明人： Robert Murphy , Andrew Woodward
IPC分类号： G06F15/173 , G06F15/177
CPC分类号： G06F17/30067 , H04L41/0803 , H04L41/0843 , H04L41/0869 , H04L41/0893 , H04L41/22
摘要： In various embodiments of the invention, a server monitors a network for a startup message from a client computer as appropriate. The server may include a computer application that generates configuration instructions in response to commands from an administrator and/or information obtained from a client computer. The instructions may be in the form of scripts, data, objects, or the like. The instructions may be passed to the client computer, which may execute various administrative functions as directed. In exemplary embodiments, the instructions may command direct placement, verification and/or replacement of files, directory entries, BIOS attributes or other characterisitics of the client computer.
摘要翻译：在本发明的各种实施例中，服务器根据需要从客户端计算机监控网络的启动消息。服务器可以包括响应于来自管理员的命令和/或从客户端计算机获得的信息来生成配置指令的计算机应用程序。指令可以是脚本，数据，对象等的形式。指令可以被传递到客户端计算机，其可以按照指示执行各种管理功能。在示例性实施例中，指令可以命令直接放置，验证和/或替换客户端计算机的文件，目录条目，BIOS属性或其他特征。

49. 发明授权

US07373730B2 Tool for installing electrical boxes 失效
标题翻译：用于安装电器箱的工具
公开(公告)号：US07373730B2
公开(公告)日：2008-05-20
申请号：US11420925
申请日：2006-05-30
申请人： Robert Murphy
发明人： Robert Murphy
IPC分类号： G01B1/00
CPC分类号： H02G3/123 , H02G1/00 , H02G2200/30 , Y10S33/10
摘要： A tool for installing various configurations of electrical boxes to framing studs during building construction includes a staff having graduations indicating distances from an end of the staff. A mounting fixture is slidably disposed on the staff and can be secured at a desired position along the length of the staff corresponding to a desired installation height for the electrical boxes. The mounting fixture may include pins for engaging apertures on an electrical box, and magnets for magnetically engaging metal electrical boxes, to help retain the electrical boxes on the mounting fixture during installation.
摘要翻译：在建筑施工期间，用于将各种配置的电气箱安装到框架螺柱上的工具包括一名工作人员，其具有指示距离工作人员一端的距离的刻度。安装夹具可滑动地布置在工作人员上，并且可以沿着与电气箱的期望的安装高度对应的工作人员的长度固定在期望的位置。安装固定件可以包括用于接合电气箱上的孔的销和用于磁性接合金属电箱的磁体，以帮助在安装期间将电箱保持在安装夹具上。

50. 发明申请

US20070277388A1 Tool For Installing Electrical Boxes 失效
标题翻译：工具用于安装电气箱
公开(公告)号：US20070277388A1
公开(公告)日：2007-12-06
申请号：US11420925
申请日：2006-05-30
申请人： Robert Murphy
发明人： Robert Murphy
IPC分类号： G01D21/00
CPC分类号： H02G3/123 , H02G1/00 , H02G2200/30 , Y10S33/10
摘要： A tool for installing various configurations of electrical boxes to framing studs during building construction includes a staff having graduations indicating distances from an end of the staff. A mounting fixture is slidably disposed on the staff and can be secured at a desired position along the length of the staff corresponding to a desired installation height for the electrical boxes. The mounting fixture may include pins for engaging apertures on an electrical box, and magnets for magnetically engaging metal electrical boxes, to help retain the electrical boxes on the mounting fixture during installation.
摘要翻译：在建筑施工期间，用于将各种配置的电气箱安装到框架螺柱上的工具包括一名工作人员，其具有指示距离工作人员一端的距离的刻度。安装夹具可滑动地布置在工作人员上，并且可以沿着与电气箱的期望的安装高度对应的工作人员的长度固定在期望的位置。安装固定件可以包括用于接合电气箱上的孔的销和用于磁性接合金属电箱的磁体，以帮助在安装期间将电箱保持在安装夹具上。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式