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41. 发明授权

US06974454B2 Transmural ablation device with thermocouple for measuring tissue temperature 有权
标题翻译：具有用于测量组织温度的热电偶的跨膜消融装置
公开(公告)号：US06974454B2
公开(公告)日：2005-12-13
申请号：US10015303
申请日：2001-12-12
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B17/00 , A61B18/14 , A61B18/18
CPC分类号： A61B18/1445 , A61B18/14 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00023 , A61B2018/00363 , A61B2018/00642 , A61B2018/00738 , A61B2018/00755 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1432 , A61B2018/145
摘要： A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then applied between the two electrodes, or the probes are cryogenically cooled, thus ablating the tissue therebetween. A monitoring device measures a suitable parameter, such as impedance or temperature, and indicates when the tissue between the electrodes has been fully ablated.
摘要翻译：使用包含两个电极或低温探针的仪器进行透壁消融的方法和装置。夹紧力施加在两个电极或探针上，使得中空器官的组织夹在其间。然后将双极RF能量施加在两个电极之间，或者探针被低温冷却，从而烧蚀它们之间的组织。监测装置测量合适的参数，例如阻抗或温度，并指示电极之间的组织何时完全消融。

42. 发明授权

US6086586A Bipolar tissue grasping apparatus and tissue welding method 有权
标题翻译：双极组织抓取装置和组织焊接方法
公开(公告)号：US6086586A
公开(公告)日：2000-07-11
申请号：US152397
申请日：1998-09-14
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/14 , A61B18/18
CPC分类号： A61B18/1442 , A61B2018/00101 , A61B2018/00589 , A61B2018/126
摘要： A bipolar electrosurgical instrument having a pair of relatively moveable jaws, each of which includes a tissue contacting surface. The tissue contacting surfaces of the jaws are in face-to-face relation with one another, and adjacent each of the tissue contacting surfaces are first and second spaced-apart electrodes that are adapted for connection to the opposite terminals of a bipolar RF generator so as to generator a current flow therebetween. The first and second electrodes of one jaw are in opposed relation, respectively, with the first and second electrodes of the other jaw. The tissue contacting surfaces are disposed between the electrodes on each jaw, and the first opposed electrodes of each jaw are connectable to one terminal of the bipolar RF generator, while the second opposed electrodes of each jaw are connectable to the other terminal of the bipolar RF generator.
摘要翻译：一种双极电外科器具，具有一对相对可移动的钳口，每个钳口包括组织接触表面。钳口的组织接触表面彼此面对面地连接，并且每个组织接触表面相邻的第一和第二间隔开的电极适于连接到双极RF发生器的相对端子，因此以产生它们之间的电流。一个钳口的第一和第二电极分别与另一个钳口的第一和第二电极相对。组织接触表面设置在每个钳口上的电极之间，并且每个钳口的第一相对电极可连接到双极RF发生器的一个端子，而每个钳口的第二相对电极可连接到双极RF的另一个端子发电机。

43. 发明授权

US6007512A Apparatus and method for morselating and removing tissue from a patient 失效
公开(公告)号：US6007512A
公开(公告)日：1999-12-28
申请号：US924806
申请日：1997-09-05
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B17/00 , A61B17/32 , A61B17/34 , A61B18/14 , A61M1/00 , A61B17/20 , A61B17/22
CPC分类号： A61B17/32002 , A61B18/1487 , A61B17/3421 , A61B2017/00287 , A61B2017/320024 , A61B2017/32004 , A61B2017/320775 , A61B2018/00208 , A61B2018/1253 , A61B2018/126 , A61B2018/162 , A61B2018/1861 , A61B2217/005 , A61B2218/007
摘要： A method for morselating and removing the morselated tissue through a small incision comprising in general inserting a tissue container into the body cavity of a patient through an incision, placing resected tissue in the vessel, inserting a morselator having a rotatable electrode thereon through the incision and into the vessel, morselating the tissue and removing the tissue from the containment vessel and the body. An apparatus for morselating and removing tissue through a small incision within the body cavity of a patient is also disclosed and may comprise a tissue container having an inner chamber for containing resected tissue, and a morselator having a proximal end and a distal end carrying an electrode wherein the distal end is insertable into the body cavity and containment vessel for morselating resected tissue.

44. 发明授权

US4769002A Intercranial pressure regulator valve 失效
标题翻译：颅内压调节阀
公开(公告)号：US4769002A
公开(公告)日：1988-09-06
申请号：US837333
申请日：1986-02-28
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61M27/00 , F16K15/14
CPC分类号： F16K15/144 , A61M27/006 , Y10T137/7834 , Y10T137/7927
摘要： An intercranial pressure regulator valve adapted particularly for the treatment of hydrocephalus and the draining of cerebrospinal fluid (CSF) from a ventricle in the brain to another location in the patient's body includes a movable, flexible diaphragm having first and second surfaces of substantial area which are contacted by the fluid which is being drained and the fluid in the area to which the CSF is to be drained, respectively. A valve seat on the diaphragm is movable therewith and the valve seat includes a passage for the flow of the fluid which is being drained through the diaphragm. A ball closure valve is positioned on the cephalad side of the diaphragm. When the pressure differential on both surfaces of the diaphragm is low, the valve seat flexes into engagement with the ball closure valve to close the passage. When the pressure differential between these two surfaces increases, the diaphragm flexes in response to the increase such that the valve seat moves away from the ball closure valve to open the passage and drain the CSF from the ventricle to the other location in the body.
摘要翻译：适用于特别用于治疗脑积水的脑内压力调节阀，以及将脑脊液从脑室中排出到患者体内的另一位置的可动的柔性隔膜，其具有第一表面和第二表面，分别被排出的流体和CSF排出的区域中的流体接触。隔膜上的阀座可与其一起移动，阀座包括用于流经隔膜的流体流动的通道。球闭合阀位于隔膜的头部侧。当隔膜的两个表面上的压力差低时，阀座弯曲成与球阀关闭，以关闭通道。当这两个表面之间的压差增加时，隔膜响应于增加而弯曲，使得阀座从球闭合阀移开以打开通道并将CSF从心室排出到体内的另一个位置。

45. 发明授权

US4714458A Three stage valve with flexible valve seat 失效
标题翻译：具有柔性阀座的三级阀
公开(公告)号：US4714458A
公开(公告)日：1987-12-22
申请号：US812771
申请日：1985-12-23
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61M27/00
CPC分类号： A61M27/006 , G05D7/012 , Y10T137/7792 , Y10T137/7834
摘要： An implantable valve for controlling the passage of cerebrospinal fluid (CSF) from a ventricle of the brain to a suitable drainage location in the body includes a movable diaphragm, one side of which is in pressure communication with the drainage location of the body and the other side of which is in pressure communication with the ventricular spaces of the brain. The diaphragm includes a flexible valve seat which moves relative to a valve closure means and a fluid flow control means in response to applied pressure differentials, thus regulating passage of CSF from the ventricular spaces to the drainage location. When the pressure differential is relatively small, the valve operates in a constant pressure mode to maintain a predetermined pressure differential across the valve. In response to a sudden increase in differential pressure, the valve operates in a constant flow mode to maintain a desired relatively constant CSF flow rate through the valve. Above a predetermined pressure differential, the valve operates n a constant pressure mode to maintain a predetermined maximum pressure differential across the valve.
摘要翻译：用于控制脑脊液（CSF）从脑室流通到体内适当引流位置的可植入阀包括可移动隔膜，其一侧与身体的排泄位置压力连通，另一侧其一侧与脑的心室空间压力相通。隔膜包括柔性阀座，其相对于阀闭合装置移动并响应于所施加的压力差流动流体控制装置，从而调节CSF从心室空间到排出位置的通道。当压差相对较小时，阀以恒定压力模式运行，以保持跨阀的预定压力差。响应于差压的突然增加，阀以恒定流动模式运行，以保持通过阀所需的相对恒定的CSF流速。在预定的压力差之上，阀在恒定压力模式下运行，以保持跨阀的预定最大压差。

46. 发明授权

US4627832A Three stage intracranial pressure relief valve having single-piece valve stem 失效
标题翻译：三级颅内压力释放阀具有单件阀杆
公开(公告)号：US4627832A
公开(公告)日：1986-12-09
申请号：US608137
申请日：1984-05-08
申请人： Michael D. Hooven , Christian Sainte-Rose
发明人： Michael D. Hooven , Christian Sainte-Rose
IPC分类号： A61M27/00 , A61M5/00
CPC分类号： A61M27/006 , Y10T137/7834
摘要： An implantable valve for allowing the passage of cerebrospinal fluid (CSF) from a ventricle of the brain to a suitable drainage location in the body includes a movable diaphragm, one side of which is in pressure communication with the drainage location of the body and the other side of which is in pressure communication with the ventricular spaces of the brain. A valve assembly, actuable by displacement of the diaphragm in response to applied pressure differentials, regulates passage of CSF from the ventricular spaces to the drainage location. When the pressure differential is relatively small, the valve operates in a constant pressure mode to maintain a predetermined pressure differential across the valve. In response to a sudden increase in differential pressure, the valve mechanism operates in a constant flow mode to maintain a desired relatively constant CSF flow rate through the valve. Above a predetermined pressure differential, the valve operates in a constant pressure mode to maintain a predetermined maximum pressure differential across the valve. To simplify construction, the valve includes a single-piece valve stem having a ramp surface at one end and a fluid restrictor surface at the other end which cooperate with the valve diaphragm to provide the three operating modes.
摘要翻译：用于允许脑脊液（CSF）从脑的脑室通过到体内合适的引流位置的可植入阀包括可移动的隔膜，其一侧与身体的排泄位置压力连通，另一侧其一侧与脑的心室空间压力相通。通过响应于施加的压力差使隔膜移动而致动的阀组件调节CSF从心室空间到排水位置的通过。当压差相对较小时，阀以恒定压力模式运行，以保持跨阀的预定压力差。响应于差压的突然增加，阀机构以恒定流动模式运行，以保持通过阀所需的相对恒定的CSF流速。在预定的压力差之上，阀以恒定压力模式运行，以保持阀上的预定的最大压差。为了简化结构，阀包括一端具有一个斜面的单件式阀杆，另一端具有一个流体限制器表面，与阀膜相配合以提供三种操作模式。

47. 发明申请

US20130018326A1 MEDICAL FLUID INJECTION DEVICE AND SYSTEM 审中-公开
标题翻译：医用流体注射装置和系统
公开(公告)号：US20130018326A1
公开(公告)日：2013-01-17
申请号：US13637756
申请日：2011-03-31
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61M5/32 , A61J1/20
CPC分类号： A61M5/20 , A61M5/14248 , A61M5/152 , A61M5/2425 , A61M5/326 , A61M5/3287 , A61M2005/14252 , A61M2005/14256 , A61M2005/3267 , A61M2202/30
摘要： A medical fluid injection device and/or medical fluid vial are disclosed. The medical fluid vial includes an outer body with a mouth and an inner member having a resilient expandable container portion and an access portion normally sealing the container portion. The injection device has a housing or needle holder mounting an access member for accessing the vial contents and a needle for injection into a patient. The housing may include a needle shield movable relative to the needle holder.
摘要翻译：公开了一种药液注射装置和/或医用流体小瓶。医用流体小瓶包括具有口部的外部本体和具有弹性可膨胀容器部分的内部构件和通常密封容器部分的通路部分。注射装置具有安装用于进入小瓶内容物的入口构件的壳体或针座，以及用于注射到患者体内的针。壳体可以包括相对于针保持器可移动的针罩。

48. 发明申请

US20100274129A1 Apparatus And Methods for Separating Pericardial Tissue From The Epicardium of the Heart 审中-公开
标题翻译：从心脏心包中分离心包组织的装置和方法
公开(公告)号：US20100274129A1
公开(公告)日：2010-10-28
申请号：US12767280
申请日：2010-04-26
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B17/00 , A61B6/00 , A61B17/34
CPC分类号： A61B17/00234 , A61B5/0215 , A61B5/042 , A61B5/065 , A61B6/12 , A61B17/3478 , A61B2017/00243 , A61B2017/320044 , A61B2090/064
摘要： Systems and methods for separating pericardial tissue from the epicardium of the heart are disclosed. The apparatus includes a catheter comprising an elongated body, including a proximal end and a distal end and a lumen extending therebetween. The apparatus further comprises a needle carried at the distal end of the catheter. The needle includes a proximal end, a distal end, and a lumen extending between the proximal and distal ends, and is in fluid communication with the catheter lumen. The needle is of a length sufficient to penetrate myocardial tissue of the heart, from the endocardium to and through the epicardium. A coupling on the catheter is provided for communication with a fluid source, to facilitate flow of fluid through the catheter lumen and needle lumen. Fluid can thereby flow through the catheter and needle lumens to a location between the epicardium and pericardial tissue. Fluid flow to this location serves, among other things, to separate the pericardial tissue from the epicardium of the heart.
摘要翻译：公开了从心脏心外膜分离心包组织的系统和方法。该装置包括导管，其包括细长主体，其包括近端和远端以及在其间延伸的内腔。该装置还包括在导管的远端处承载的针。针包括近端，远端和在近端和远端之间延伸并且与导管腔流体连通的内腔。该针的长度足以穿透心脏的心肌组织，从心内膜到心外膜并通过心外膜。导管上的联接件被提供用于与流体源连通，以促进流体流过导管内腔和针腔。因此，流体可以通过导管流动并将针腔流到心外膜组织和心包组织之间的位置。除了别的以外，到这个位置的流体流动可以将心包组织与心脏的心外膜分开。

49. 发明授权

US07393353B2 Transmural ablation device with temperature sensor 有权
标题翻译：具有温度传感器的透壁消融装置
公开(公告)号：US07393353B2
公开(公告)日：2008-07-01
申请号：US10920574
申请日：2004-08-18
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61B18/14
CPC分类号： A61B18/1445 , A61B18/14 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00023 , A61B2018/00363 , A61B2018/00642 , A61B2018/00738 , A61B2018/00755 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1432 , A61B2018/145
摘要： A method and apparatus for transmural ablation using an instrument containing first and second jaw member and at least one of the jaw members having an ablation member. A clamping force is exerted on the jaw members such that the tissue of the hollow organ is clamped therebetween. An ablation energy source is then applied thus ablating the tissue between the jaw members. A monitoring device measures a suitable parameter, such as impedance or temperature, and indicates when the tissue has been fully ablated.
摘要翻译：一种用于使用包含第一和第二钳口构件的仪器进行透壁消融的方法和装置，以及具有消融构件的至少一个钳口构件。夹钳力施加在钳口构件上，使得中空器官的组织夹在其间。然后施加消融能量源，从而消除钳口构件之间的组织。监测装置测量适当的参数，例如阻抗或温度，并指示组织何时完全消融。

50. 发明授权

US07113831B2 Transmural ablation device 有权
公开(公告)号：US07113831B2
公开(公告)日：2006-09-26
申请号：US10015346
申请日：2001-12-12
申请人： Michael D. Hooven
发明人： Michael D. Hooven
IPC分类号： A61F2/00
CPC分类号： A61B18/1445 , A61B18/14 , A61B2017/00026 , A61B2017/00243 , A61B2017/2945 , A61B2018/00023 , A61B2018/00363 , A61B2018/00642 , A61B2018/00738 , A61B2018/00755 , A61B2018/00875 , A61B2018/0212 , A61B2018/0225 , A61B2018/0262 , A61B2018/1432 , A61B2018/145
摘要： A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then applied between the two electrodes, or the probes are cryogenically cooled, thus ablating the tissue therebetween. A monitoring device measures a suitable parameter, such as impedance or temperature, and indicates when the tissue between the electrodes has been fully ablated.

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