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41. 发明申请

US20110230746A1 METHOD, IMPLANTABLE MEDICAL DEVICE, AND SYSTEM FOR DETERMINING THE CONDITION OF A HEART VALVE 有权
标题翻译：方法，可植入医疗装置和用于确定心脏瓣膜状态的系统
公开(公告)号：US20110230746A1
公开(公告)日：2011-09-22
申请号：US13131824
申请日：2008-11-28
申请人： Karin Jarverud , Andreas Blomovist
发明人： Karin Jarverud , Andreas Blomovist
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/02028 , A61B5/04012 , A61B5/042 , A61B5/0432 , A61B5/076 , A61B5/4836 , A61B5/686 , A61B2562/0214 , A61B2562/227 , A61N1/3627 , A61N1/36521 , A61N1/368 , A61N1/3682 , A61N1/3684 , A61N1/3702
摘要： An implantable medical device has an impedance processor for determining atrial impedance data reflective of the cardiogenic impedance of an atrium of a heart during diastole and/or systole of heart cycle. Ventricular impedance data reflective of the cardiogenic impedance of a ventricle during diastole and/or systole are also determined. The determined impedance data are processed by a representation processor for estimating a diastolic and/or a systolic atrial impedance representation and a diastolic and/or a systolic ventricular impedance representation. A condition processor determines the presence of any heart valve malfunction, such as valve regurgitation and/or stenosis, of at least one heart valve based on the estimated atrial and ventricular impedance representations.
摘要翻译：可植入医疗装置具有阻抗处理器，用于在舒张期和/或心脏周期收缩期间确定反映心脏心房的心源阻抗的心房阻抗数据。还确定了反映舒张期和/或收缩期心室心源阻抗的心室阻抗数据。确定的阻抗数据由用于估计舒张和/或收缩期心房阻抗表示以及舒张和/或收缩期心室阻抗表示的表示处理器处理。条件处理器基于估计的心房和心室阻抗表示来确定至少一个心脏瓣膜的任何心脏瓣膜故障（例如瓣膜反流和/或狭窄）的存在。

42. 发明授权

US08000790B2 Device for adjusting the sensitivity level of an implantable medical device 有权
标题翻译：用于调节植入式医疗装置的灵敏度水平的装置
公开(公告)号：US08000790B2
公开(公告)日：2011-08-16
申请号：US10576178
申请日：2003-10-27
申请人： Anders Björling , Nils Holmström , Karin Järverud , Martin Obel
发明人： Anders Björling , Nils Holmström , Karin Järverud , Martin Obel
IPC分类号： A61N1/00 , A61B5/04
CPC分类号： A61N1/3704 , A61B5/0452 , A61N1/368
摘要： An implantable cardiac stimulation device has an atrial detector that detects atrial events of a patient's heart, and a memory in which sequences of IEGM signals are stored, having a predetermined length, and an analyzing unit that analyzes the sequences to determine if the stored sequences contain atrial events having a lower amplitude than the current sensitivity setting of the atrial detector. A control unit is connected to the atrial detector to adjust the sensitivity setting thereof to a threshold that is determined based on the aforementioned analysis of the IEGM signals.
摘要翻译：可植入心脏刺激装置具有心房检测器，其检测患者心脏的心房事件，以及存储具有预定长度的IEGM信号序列的存储器，以及分析单元，其分析序列以确定所存储的序列是否包含心房事件的振幅低于心房检测器的当前灵敏度设置。控制单元连接到心房检测器以将其灵敏度设置调整到基于上述对IEGM信号的分析确定的阈值。

43. 发明申请

US20110160605A1 IMPLANTABLE HEART MONITORING DEVICE AND METHOD 有权
标题翻译：可注入的心脏监测装置和方法
公开(公告)号：US20110160605A1
公开(公告)日：2011-06-30
申请号：US13060649
申请日：2008-08-29
申请人： Andreas Blomqivst , Michael Broomé
发明人： Andreas Blomqivst , Michael Broomé
IPC分类号： A61B5/042
CPC分类号： A61B5/026 , A61B5/0245 , A61B5/029 , A61B5/042 , A61B5/0452 , A61B5/053 , A61B5/6846 , A61N1/3627 , A61N1/36585
摘要： In an implantable heart monitoring device and method, particularly for monitoring diastolic dysfunction, a control circuit (a) detects the heart rate, (b) derives information correlated to the stroke volume of the heart at the detected heart rate, and (c) stores the detected heart rate and the derived information correlated to the stroke volume in a memory. The control circuit automatically implements (a), (b) and (c) at a number of different occasions for a number of different, naturally varying heart rates, so that the memory contains information indicating the stroke volume as a function of the heart rate.
摘要翻译：在可植入心脏监测装置和方法中，特别是用于监测舒张功能障碍，控制电路（a）检测心率，（b）以检测到的心率导出与心脏的搏动体积相关的信息，以及（c）检测到的心率和导出的信息与存储器中的笔画体积相关。控制电路在许多不同的，自然变化的心率的多个不同场合自动实现（a），（b）和（c），使得存储器包含指示作为心率的函数的行程体积的信息。

44. 发明授权

US07908005B2 Medical system for monitoring and localization of electrode leads in the heart 有权
标题翻译：用于心脏中电极引线的监测和定位的医疗系统
公开(公告)号：US07908005B2
公开(公告)日：2011-03-15
申请号：US12294268
申请日：2006-03-27
申请人： Sven-Erik Hedberg , Kenth Nilsson
发明人： Sven-Erik Hedberg , Kenth Nilsson
IPC分类号： A61N1/365
CPC分类号： A61N1/37 , A61B2034/2053 , A61N1/368 , A61N1/3682 , A61N1/3684 , A61N1/3704
摘要： A medical system has an implantable heart stimulator with sensing and stimulating pairs of electrodes, with an electric field through the heart being generated by the respective pairs by the application of alternating voltages at a preset frequency to the respective pairs. A signal receiver receives a signal representing the voltage potential difference between the voltage potential at one of the electrodes in the pair, and a reference electrode. The detected voltage is related to the generated electric field, and the signal receiver generates a potential different signal that is supplied to a control unit to determine parameters therefrom representing cardiac activity.
摘要翻译：医疗系统具有可植入的心脏刺激器，其具有感测和刺激电极对，其中通过将预定频率的交变电压施加到相应的对，由相应的对产生心脏的电场。信号接收器接收表示一对电极之间的电压电位与参考电极之间的电压电位差的信号。检测到的电压与所产生的电场相关，并且信号接收器产生提供给控制单元的电位不同信号，以确定代表心脏活动的参数。

45. 发明授权

US07908002B2 Heart stimulator detecting atrial arrhythmia by determining wall distension by impedance measuring 有权
标题翻译：心脏刺激器通过阻抗测量确定壁膨胀来检测房性心律失常
公开(公告)号：US07908002B2
公开(公告)日：2011-03-15
申请号：US10540604
申请日：2003-08-19
申请人： Carl-Johan Höijer
发明人： Carl-Johan Höijer
IPC分类号： A61N1/365
CPC分类号： A61N1/36521
摘要： In an implantable pacemaker, pacing pulses are delivered to a ventricle in a P-wave synchronous mode as long as no atrial arrhythmia is detected, pacing pulses and a mode switch is made to deliver pacing pulses to the ventricle in a non-P-wave synchronous mode if atrial arrhythmia is detected. From an impedance signal measured in the atrium, atrial distention is determined and, in the non-P-wave synchronous mode, the delivery rate of the pacing pulses is increased to decrease the atrial distention during atrial arrhythmia.
摘要翻译：在植入式心脏起搏器中，只要没有检测到心房心律不齐，起搏脉冲就以P波同步模式输送到心室，起搏脉冲和模式开关用于在非P波中向心室输送起搏脉冲检测到心房心律不齐的同步模式。根据在心房测量的阻抗信号，确定心房膨胀，并且在非P波同步模式中，起搏脉冲的输送速率增加以降低心房心律失常期间的心房膨胀。

46. 发明申请

US20100160992A1 IMPLANTABLE MEDICAL DEVICE, SYSTEM AND METHOD 审中-公开
标题翻译：可植入医疗装置，系统和方法
公开(公告)号：US20100160992A1
公开(公告)日：2010-06-24
申请号：US12600542
申请日：2007-05-28
申请人： Andreas Blomqvist
发明人： Andreas Blomqvist
IPC分类号： A61N1/365
CPC分类号： A61N1/36521 , A61B5/0205 , A61B5/076 , A61B5/0809 , A61N1/3601 , A61N1/36557
摘要： In an implantable medical device and method for monitoring a lung deficiency in a patient, a housing containing a control circuit. Is implanted in a patient. The control circuit is configured to analyze one or more signals that represent the breathing of the patient. The control circuit is also configured to monitor a relationship between an expiratory phase and an inspiratory phase of the breathing cycle, or an analogous relationship, and to monitor a change in the lung deficiency by monitoring a change in this relationship.
摘要翻译：在用于监测患者的肺缺血的可植入医疗装置和方法中，包含控制电路的壳体。植入患者。控制电路被配置为分析表示患者呼吸的一个或多个信号。控制电路还被配置为监测呼吸周期的呼气阶段和吸气阶段之间的关系或类似的关系，并且通过监视该关系的变化来监测肺缺血的变化。

47. 发明授权

US07725189B2 Method, device, and system concerning heart stimulation 有权
标题翻译：心脏刺激的方法，装置和系统
公开(公告)号：US07725189B2
公开(公告)日：2010-05-25
申请号：US11660771
申请日：2004-08-31
申请人： Anders Björling
发明人： Anders Björling
IPC分类号： A61N1/37
CPC分类号： A61N1/371
摘要： In a cardiac stimulation method, device and system, a capture verification condition is determined. For this purpose, a number of pacing pulses are delivered to a heart chamber and signals are sensed within a time window following each pacing pulse. The sensed signals are stored and categorized as representing capture or non-capture. Using the stored signals, a weight vector is determined, that assigns different weights for different parts of each sensed signal within the time window. The weight vector is used for calculating a weighted area within the time window. The capture verification condition is determined by identifying whether the weighted area, calculated with the weight vector, of a sensed signal within the time window is above or below a predetermined value.
摘要翻译：在心脏刺激方法，装置和系统中，确定捕获验证条件。为此，将多个起搏脉冲输送到心室，并且在每个起搏脉冲之后的时间窗内感测信号。感测到的信号被存储并分类为表示捕获或非捕获。使用存储的信号，确定权重向量，其在时间窗口内为每个感测信号的不同部分分配不同的权重。权重向量用于计算时间窗口内的加权区域。通过识别在时间窗内的感测信号的权重向量计算的加权面积是否高于或低于预定值来确定捕获验证条件。

48. 发明申请

US20100106222A1 METHOD AND SYSTEM FOR INITIATING COMMUNICATION BETWEEN A HOME MONITORING DEVICE AND AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于启动家庭监控设备和可植入医疗设备之间的通信的方法和系统
公开(公告)号：US20100106222A1
公开(公告)日：2010-04-29
申请号：US12531567
申请日：2007-03-27
申请人： Leif Lychou , Jan Ljungstrom , Niklas Sköldengen , Hans Abrahamson
发明人： Leif Lychou , Jan Ljungstrom , Niklas Sköldengen , Hans Abrahamson
IPC分类号： A61N1/08 , H04Q9/00
CPC分类号： A61N1/37276
摘要： In a method and system for establishing a wireless communication session between an implantable medical device IMD and a home monitoring device, the home monitoring device frequently sends communication-initiating signals to an IMD arranged within the body of a patient for establishing a communication session between the monitoring device and the IMD. In order to save energy, RF telemetry circuitry of the IMD is normally set in a low-power, idle mode. Occasionally, the RF circuitry will leave the low-power mode and enter an active mode in which it is able to detect a communication-initiating signal transmitted by the monitoring device. When a communication-initiating signal is detected, the IMD will respond accordingly to the monitoring device and a communication session will be established. In the present invention, the telemetry circuitry of the IMD will be controlled to wake up from low-power mode and enter an active detection mode independently of the transmission of the communication-initiating signals from the monitoring device. Hence, the external monitoring device will frequently transmit communication-initiating signals, but the IMD will only detect a wakeup signal when leaving its low-power mode and entering active mode at a predetermined instant of time.
摘要翻译：在用于在可植入医疗装置IMD和家庭监视装置之间建立无线通信会话的方法和系统中，家庭监视装置经常向布置在患者体内的IMD发送通信发起信号，以建立在病人身体之间的通信会话监控设备和IMD。为了节约能源，IMD的RF遥测电路通常设置在低功耗，空闲模式。偶尔，RF电路将离开低功率模式并进入有效模式，在该模式下，它能够检测监控设备发送的通信启动信号。当检测到通信发起信号时，IMD将相应地对监视设备进行响应，并建立通信会话。在本发明中，IMD的遥测电路将被控制为从低功率模式唤醒并且独立于来自监视设备的通信启动信号的传输而进入主动检测模式。因此，外部监视装置将频繁地发送通信启动信号，但是IMD将仅在预定时刻离开其低功率模式并进入主动模式时检测唤醒信号。

49. 发明申请

US20100013668A1 METHOD IN A MEDICAL TELEMETRY SYSTEM AND MEDICAL TELEMETRY SYSTEM 审中-公开
标题翻译：医疗电报系统和医疗电报系统中的方法
公开(公告)号：US20100013668A1
公开(公告)日：2010-01-21
申请号：US12522022
申请日：2007-01-31
申请人： Ingemar Kantervik
发明人： Ingemar Kantervik
IPC分类号： H04Q9/00
CPC分类号： A61N1/08 , A61B5/0031 , A61N1/37252 , H04L1/1877 , H04L67/12
摘要： In a method and a medical telemetry system for communication between an external monitoring device and an implantable medical device of the medical telemetry system at a transmitting end, an implantable medical device frame layer packet is segmented into one or more data blocks of a radio packet. The data blocks are transmitted in the communication between the external monitoring device and the implantable medical device. A start of the implantable medical device is indicated in the frame layer packet by including in a first data block of the radio packet a segmentation and reassembly indicator having a first value. At the transmitting end, the data blocks are transmitted over a short-range medical radio link. At the receiving end, the data blocks are reassembled into the originally transmitted implantable medical device frame layer packet.
摘要翻译：在用于在发送端的医疗遥测系统的外部监视装置和可植入医疗装置之间进行通信的方法和医疗遥测系统中，可植入医疗装置帧层分组被分割成无线分组的一个或多个数据块。在外部监视装置和可植入医疗装置之间的通信中发送数据块。通过在无线电分组的第一数据块中包括具有第一值的分段和重组指示符，在帧层分组中指示可植入医疗装置的开始。在发送端，通过短程医疗无线电链路传输数据块。在接收端，将数据块重新组装到原始传输的可植入医疗设备帧层分组中。

50. 发明授权

US07569020B2 Method for extracting timing parameters using a cardio-mechanical sensor 有权
标题翻译：使用心机械传感器提取定时参数的方法
公开(公告)号：US07569020B2
公开(公告)日：2009-08-04
申请号：US11455518
申请日：2006-06-19
申请人： Kjell Norén , Nils Holmström
发明人： Kjell Norén , Nils Holmström
IPC分类号： A61B5/026
CPC分类号： A61B5/02416 , A61B5/0031 , A61B5/0452 , A61B5/083 , A61B5/1116 , A61B5/686 , A61B5/7239 , A61N1/36514 , A61N1/36578
摘要： In a method and apparatus for measuring the ejection fraction in a mammalian heart, the opening and closing of a heart valve is sensed with an implanted sensor, and a pre-ejection period is measured as a function of the sensed opening and closing of the heart valve. The ventricular ejection time also is measured, and the ejection fraction is determined as a function of the measured pre-ejection period and the ejection time.
摘要翻译：在用于测量哺乳动物心脏中的射血分数的方法和装置中，用植入的传感器感测心脏瓣膜的打开和关闭，并且根据检测到的心脏的开启和关闭来测量预喷射周期阀。也测量心室射血时间，并且将射血分数确定为所测量的预喷射时间和喷射时间的函数。

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