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31. 发明授权

US06577889B2 Radiographic image diagnosis apparatus capable of displaying a projection image in a similar position and direction as a fluoroscopic image 有权
标题翻译：能够以与透视图像相同的位置和方向显示投影图像的射线照相图像诊断装置
公开(公告)号：US06577889B2
公开(公告)日：2003-06-10
申请号：US09977504
申请日：2001-10-16
申请人： Masahide Ichihashi
发明人： Masahide Ichihashi
IPC分类号： A61B505
CPC分类号： A61B6/481 , A61B6/02 , A61B6/12 , A61B6/4233 , A61B6/4441 , A61B6/463 , A61B6/464 , A61B6/466 , A61B6/469 , A61B6/504 , A61B6/547 , A61B6/588 , A61B6/589
摘要： A radiographic image diagnosis apparatus includes a photographing unit having a radiation source and a 2D radiation detector to generate data of a fluoroscopic image of an object to be examined. Volume data is generated on the basis of the data of plurality of fluoroscopic images of the object at different angles which are acquired by the photographing unit. A measuring mechanism measures the position and angle of the photographing unit with respect to the object. Projection image data is generated from the volume data on the basis of the position and angle of the photographing unit which are measured by the measuring mechanism. The volume data is then displayed. This makes it possible to display the projection image with substantially the same position and direction as those of a fluoroscopic image.
摘要翻译：射线照相图像诊断装置包括具有辐射源和2D辐射检测器的拍摄单元，用于生成待检查对象的透视图像的数据。基于由拍摄单元获取的以不同角度的对象的多个透视图像的数据生成体数据。测量机构测量拍摄单元相对于物体的位置和角度。基于由测量机构测量的拍摄单元的位置和角度，从音量数据生成投影图像数据。然后显示音量数据。这使得可以以与透视图像的位置和方向基本相同的位置和方向来显示投影图像。

32. 发明授权

US06574496B1 Magnetic resonance imaging 失效
标题翻译：磁共振成像
公开(公告)号：US06574496B1
公开(公告)日：2003-06-03
申请号：US09572949
申请日：2000-05-18
申请人： Klaes Golman , Oskar Axelsson , Haukur Johannesson
发明人： Klaes Golman , Oskar Axelsson , Haukur Johannesson
IPC分类号： A61B505
CPC分类号： G01R33/5601 , G01R33/56308
摘要： A method of magnetic resonance investigation of a sample by (i) reacting ortho-deuterium enriched hydrogen with a hydrogenatable MR imaging agent precursor to produce a hydrogenated (i.e. deuterated) MR imaging agent; (ii) optionally, subjecting the hydrogenated MR imaging agent to a low magnetic field;(iii) administering the hydrogenated MR imaging agent to the sample; (iv) exposing the sample to radiation of a frequency selected to excite nuclear spin transitions of selected non-zero nuclear spin nuclei in said hydrogenated MR imaging agent; (v) detecting magnetic resonance signals of the selected non-zero nuclear spin nuclei from the sample; and (vi) optionally, generating an image or biological functional data or dynamic flow data from the detected signals.
摘要翻译：通过（i）使富氘氢与可氢化MR显像剂前体反应以产生氢化（即氘代）MR成像剂，对样品进行磁共振研究的方法; （ii）任选地，使氢化MR成像剂经受低磁场;（iii）向该样品施用氢化MR显像剂; （iv）将所述样品暴露于所选择的用于激发所述氢化MR成像剂中选定的非零核自旋核的核自旋跃迁的频率的辐射; （v）从所述样品检测所选择的非零核自旋核的磁共振信号; 和（vi）可选地，从检测到的信号生成图像或生物功能数据或动态流量数据。

33. 发明授权

US06567686B2 Method for improving lung delivery of pharmaceutical aerosols 失效
标题翻译：改善药物气溶胶肺输送的方法
公开(公告)号：US06567686B2
公开(公告)日：2003-05-20
申请号：US09825011
申请日：2001-04-03
申请人： Frederick Sexton , Akwete L. Adjei , Perry Arthur Genova , Richard Joel Melker , Johannes Hugo van Oostrom , Ilona Maria Schmalfuss , Anthony A. Mancuso
发明人： Frederick Sexton , Akwete L. Adjei , Perry Arthur Genova , Richard Joel Melker , Johannes Hugo van Oostrom , Ilona Maria Schmalfuss , Anthony A. Mancuso
IPC分类号： A61B505
CPC分类号： A61B5/411 , A61B5/055 , A61B5/0813 , Y10S128/922
摘要： Disclosure is made of a method employing real-time imaging techniques such as Magnetic Resonance Imaging in order to investigate the effect of air way structures or administration and respiratory drugs when administered by oral inhalation. The information obtained from the practice of this method yields the criteria that can be used, among other things, to design more efficient aerosol drug delivery systems which optimize the amount of medicine delivered to the lung.
摘要翻译：公开了采用诸如磁共振成像技术的实时成像技术的方法，以便通过口服吸入来研究气道结构或给药和呼吸药物的作用。从该方法的实践获得的信息产生了可用于设计更有效的气溶胶药物递送系统的标准，其优化递送至肺的药物的量。

34. 发明授权

US06567683B1 Apparatus and method for conducting nuclear magnetic resonance experiments on a member of the body of a big animal 失效
标题翻译：对大动物身体的成员进行核磁共振实验的装置和方法
公开(公告)号：US06567683B1
公开(公告)日：2003-05-20
申请号：US09648213
申请日：2000-08-25
申请人： Bertold Knuettel
发明人： Bertold Knuettel
IPC分类号： A61B505
CPC分类号： A61B5/0555 , A61B5/4528 , A61B5/7207 , A61B2503/40 , G01R33/465
摘要： An apparatus is disclosed for conducting nuclear magnetic resonance experiments on an extremity of a big animal, in particular a horse. The apparatus includes a magnet assembly for receiving the extremity. A housing is provided adapted to the shape of the big animal. The housing incorporates a protrusion for receiving the extremity. The protrusion is adapted to be inserted into the magnetic assembly. A radio frequency (rf) assembly is provided for irradiating rf signals on the extremity and/or for receiving nuclear magnetic resonance signals from the extremity. The rf assembly is adapted to be attached to the protrusion.
摘要翻译：公开了用于在大动物，特别是马的末端进行核磁共振实验的装置。该装置包括用于接收末端的磁体组件。提供适应大动物形状的外壳。壳体包括用于接收肢体的突起。突起适于插入到磁性组件中。提供射频（RF）组件用于在末端照射rf信号和/或从末端接收核磁共振信号。射频组件适于附接到突起。

35. 发明授权

US06567682B1 Apparatus and method for lesion feature identification and characterization 失效
标题翻译：用于病变特征识别和表征的装置和方法
公开(公告)号：US06567682B1
公开(公告)日：2003-05-20
申请号：US09711966
申请日：2000-11-15
申请人： Josef Osterweil , Niels K. Winsor
发明人： Josef Osterweil , Niels K. Winsor
IPC分类号： A61B505
CPC分类号： A61B5/0059
摘要： An apparatus and method for determining a characteristic of a selected skin lesion. A capture device produces data representing an image of an object. A processing device processes the data to derive a three-dimensional model of the skin lesion, which is stored in a database. A reporting device indicates at least one specific property of the selected skin lesion. The processing device determines a change in at least one specific property of the skin lesion by comparing the three-dimensional model with at least one previously derived three-dimensional model that is stored in the database.
摘要翻译：一种用于确定所选皮肤损伤特征的装置和方法。捕获设备产生表示对象的图像的数据。处理装置处理数据以导出存储在数据库中的皮肤损伤的三维模型。报告装置指示所选皮肤损伤的至少一个特定属性。处理装置通过将三维模型与存储在数据库中的至少一个先前导出的三维模型进行比较来确定皮肤损伤的至少一个特定属性的变化。

36. 发明授权

US06564080B1 MR imaging on ASL technique 有权
标题翻译： ASL技术的MR成像
公开(公告)号：US06564080B1
公开(公告)日：2003-05-13
申请号：US09539775
申请日：2000-03-31
申请人： Tokunori Kimura
发明人： Tokunori Kimura
IPC分类号： A61B505
CPC分类号： A61B5/0263 , G01R33/4835 , G01R33/563
摘要： MR imaging is provided based on the ASL method providing an ASL image. In this imaging, MT effects are steadily canceled to reduce difference errors inherent in excluding stationary tissue from the image and sensitivity is given to only a signal from one-way blood flow. A first RF wave and a first magnetic gradient Gtag both for selective-exciting a tagging slab and a second RF wave and a second magnetic gradient Gcont both for selective-exciting a controlling slab are set, in which offset amounts of exciting central frequencies of both of the first and second RF waves to a central position of an imaging slab are equal to each other and offset positions Offsettag and Offsetcont of the tagging slab and the controlling slab to the imaging slab are different from each other. Both of the RF pulses are IR pulses. A pulse sequence including the first RF wave and the first magnetic gradient Gtag is performed and a pulse sequence including the second RF wave and the second magnetic gradient Gcont is performed, so that echo signals are acquired for each performance. The echo signals are subject to mutual difference calculation to provide an ASL image.
摘要翻译：基于提供ASL图像的ASL方法提供MR成像。在该成像中，MT效应被稳定地消除，以减少从图像中排除固定组织所固有的差异误差，并且仅对来自单向血流的信号提供灵敏度。设置用于选择性地激励标签板和第二RF波的第一RF波和第一磁梯度Gtag，以及用于选择性激励控制板的第二磁梯度Gcont，其中两个的激励中心频率的偏移量第一和第二RF波到成像板的中心位置彼此相等，并且标签板和控制板到成像板的偏移位置Offsettag和Offsetcont彼此不同。两个RF脉冲都是IR脉冲。执行包括第一RF波和第一磁梯度Gtag的脉冲序列，并且执行包括第二RF波和第二磁梯度Gcont的脉冲序列，从而针对每个演奏采集回波信号。回波信号经过相互差异计算，以提供ASL图像。

37. 发明授权

US06560471B1 Analyte monitoring device and methods of use 有权
标题翻译：分析物监测装置及使用方法
公开(公告)号：US06560471B1
公开(公告)日：2003-05-06
申请号：US09753746
申请日：2001-01-02
申请人： Adam Heller , Steven H. Drucker , Robert Y. Jin , Jeffery V. Funderburk
发明人： Adam Heller , Steven H. Drucker , Robert Y. Jin , Jeffery V. Funderburk
IPC分类号： A61B505
CPC分类号： A61B5/1495 , A61B5/0002 , A61B5/0022 , A61B5/0031 , A61B5/076 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/4839 , A61B5/6832 , A61B5/6833 , A61B5/6849 , A61B5/7405 , A61B5/742 , A61B5/743 , A61B5/7445 , A61B2560/0252 , A61B2560/0412 , A61B2560/063 , A61N1/08 , H04B1/707 , H04L1/0071
摘要： An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.
摘要翻译：分析物监测器包括传感器，传感器控制单元和显示单元。传感器具有例如基板，形成在基板中的凹陷通道，以及设置在凹陷通道中以形成工作电极的导电材料。传感器控制单元通常具有适于放置在皮肤上并适于接收电化学传感器的一部分的壳体。传感器控制单元还包括设置在壳体上并被配置为耦合到传感器上的两个或更多个接触垫的两个或更多个导电触头。发射器设置在壳体中并且耦合到多个导电接触件，用于传送使用传感器获得的数据。显示单元具有用于接收由传感器控制单元的发送器发送的数据的接收器和耦合到接收器的显示器以显示分析物水平的指示的接收器。分析物监测器还可以是药物递送系统的一部分，以基于使用传感器获得的数据来改变分析物的水平。

38. 发明授权

US06556854B1 Blood vessel imaging system using homodyne and heterodyne effects 失效
标题翻译：血管成像系统使用零差和外差效应
公开(公告)号：US06556854B1
公开(公告)日：2003-04-29
申请号：US09495758
申请日：2000-02-01
申请人： Tomoo Sato , Masahiro Toida , Kazuhiro Tsujita
发明人： Tomoo Sato , Masahiro Toida , Kazuhiro Tsujita
IPC分类号： A61B505
CPC分类号： A61B5/02007 , A61B5/0059
摘要： A homodyne interference system splits first and second light beams from a common light source and causes the first and second light beams to impinge upon an irradiating point of an organism at different directions. An optical heterodyne system splits a third beam from the common light source and imparts a frequency shift to the third beam. The outputs of the homodyne and heterodyne systems combine to permit extraction of a beat component of the homodyne system at a high SNR level. The output of the homodyne and heterodyne system are output as an image, which may be timed to a phase timing mechanism to provide an improved output.
摘要翻译：零差干涉系统分离来自公共光源的第一和第二光束，并且使第一和第二光束在不同方向上撞击生物体的照射点。光学外差系统将来自公共光源的第三光束分离，并向第三光束施加频移。零差和外差系统的输出结合起来，允许以高SNR水平提取零差系统的拍子分量。零差和外差系统的输出作为图像输出，其可以被定时到相位定时机构以提供改进的输出。

39. 发明授权

US06553248B1 Computing by anticipation for nuclear medicine imaging 有权
标题翻译：计算核医学成像预期
公开(公告)号：US06553248B1
公开(公告)日：2003-04-22
申请号：US09437783
申请日：1999-11-09
申请人： Daniel Gagnon , Jerome W. Brack
发明人： Daniel Gagnon , Jerome W. Brack
IPC分类号： A61B505
CPC分类号： G01T1/1647
摘要： A method for reconstructing an image representation of a subject from data sets collected using a medical diagnostic imaging apparatus is provided. The method includes defining operations which are performed in reconstructing desired types of image representations. The operations are applicable to data sets having particular formats. Data sets having particular formats are identified, and operations are selected from the defined operations based upon the particular format of the identified data sets. When a detected load on available image processing equipment is below a desired level, then selected operations are automatically performed on the identified data sets.
摘要翻译：提供了一种用于使用医学诊断成像装置收集的数据集重建对象的图像表示的方法。该方法包括定义在重建期望类型的图像表示中执行的操作。这些操作适用于具有特定格式的数据集。识别具有特定格式的数据集，并且基于所识别的数据集的特定格式从定义的操作中选择操作。当检测到的可用图像处理设备的负载低于期望的水平时，对所识别的数据集进行自动执行所选择的操作。

40. 发明授权

US06543933B2 Non-invasive 3-D intracranial thermography system 失效
公开(公告)号：US06543933B2
公开(公告)日：2003-04-08
申请号：US10046547
申请日：2002-01-16
申请人： Stergios Stergiopoulos , Nikolaos Uzunoglu
发明人： Stergios Stergiopoulos , Nikolaos Uzunoglu
IPC分类号： A61B505
CPC分类号： A61B5/015 , A61B5/0507 , A61B5/4064 , G01K11/006
摘要： A microwave thermography apparatus to measure temperatures within a dielectric body comprises a partial ellipsoidal cavity with an electrical conductive surface wherein the body can be located at one focus of the cavity. A microwave antenna located at a second focus of the cavity is connected to a radiometer. That radiometer amplifies and filters signals from the antenna before they are applied to a detector with the temperature of the body being determined from the voltage amplitude of the detected signals.

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