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    • 32. 发明授权
    • Preparation for prevention and healing of inflammation affections
    • US06610284B1
    • 2003-08-26
    • US09555626
    • 2000-07-27
    • Ji{haeck over (r)}í LabskýJi{haeck over (r)}í VacíkPavel Ho{haeck over (s)}ek
    • Ji{haeck over (r)}í LabskýJi{haeck over (r)}í VacíkPavel Ho{haeck over (s)}ek
    • A61K3174
    • C08G73/0672A61K31/785A61K31/787A61K31/79C08G73/0213C08G73/0627C08G73/0633
    • A preparation for prevention and healing of inflammation affections comprising in an amount of 0.1 to 99.9% by weight derivatives of sterically hindered amines selected from the group consisting of: soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10% by weight, of initiators prepared:in a polymerization mixture comprising individually or in combination an aliphatic amine monomer of the general formula (A), soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10% by weight of initiators from monomers of cyclic sterically hindered amines of the general formula (B), soluble polymers prepared by polycondensation of difunctional sterically hindered amines of the general formula (F), soluble polymers or copolymers prepared by polycondensation of difunctional cyclic sterically hindered amines of the general formula (G), soluble copolymers prepared by polycondensation of difunctional cyclic, sterically hindered amines of the general formula (G) and monofunctional cyclic sterically hindered amines in an amount of 0.1 to 15%. by weight, based on the total polymerization mixture, of the general formula (H), derivatives of sterically hindered cyclic amines of the general formula (O), polymers, copolymers, or natural compounds comprising free reactive groups —OH, —NH2, —COOH, —CHO, oxiranyl, selected from the group poly(vinyl alcohol), cellulose, (2-hydroxyethyl)cellulose, (carboxymethyl)celullose, agar derivatives, polymers obtained by condensation, using alkanediol derivatives, oligomers and polymers of ethylene glycol or propylene glycol, natural or synthetic polymers, comprising a free carboxyl group, amino group or aldehyde group, prepared by additional functionalization of polymers or natural compounds by polymeranalogous reaction with a suitable sterically hindered amine.
    • 36. 发明授权
    • Unsaturated polyaminopolymer, derivatives thereof and processes for
making
    • 不饱和聚氨酯聚合物,其衍生物和制备方法
    • US5278255A
    • 1994-01-11
    • US927988
    • 1992-08-11
    • Otha G. Weaver, Jr.Terry W. GlassWanda G. Buckner
    • Otha G. Weaver, Jr.Terry W. GlassWanda G. Buckner
    • C08G73/02D21H17/55C08G69/48
    • C08G73/0213D21H17/55
    • The present invention is a process for preparing a polyaminopolymer which contains functionality comprising the steps of (a) contacting a polyfunctional amine with an unsaturated alkylating agent under reaction conditions to form an amine/unsaturated alkylating agent adduct; (b) contacting the adduct with a polyfunctional compound such that a polyaminopolymer is formed; (c) contacting the polyaminopolymer with a halogen, hypohalous acid or precursor thereof such that a polyaminopolymer having halohydrin or dihalo functionality is formed; and (d) raising the pH of the polyaminopolymer having halohydrin or vicinal dihalo functionality sufficiently to cause an increase in molecular weight. Alternatively, the invention is a process having steps (a), (b), (c) and optionally (d), but with a step (h) between steps (b) and (c) of contacting the polyaminopolymer with a crosslinking agent therefor having at least two functional groups reactive with amine groups such that a crosslinked polyaminopolymer is formed. The invention includes polyaminopolymers so prepared, papers prepared using such polymers, and processes for preparing such papers. The papers so prepared preferably have improved wet strength. The polyaminopolymers are useful when dried and redissolved. Certain of the polyamino-polymers have structures of Formula IV:[--R'N--(C.sub.n H.sub.2n NR).sub.m --CO--Q--CO--]wherein R and R' are independently H or an unsaturated organic group; n is the number of carbon atoms between nitrogen atoms in a repeating unit of an amine which unit is repeated m times; and Q is divalent organic group of a dicarboxylic polyfunctional compound. Compounds of Formula IV are also made by forming a polyamide then alkylating the polyamide with excess alkylating agent at high pH.
    • 本发明是一种制备含有官能团的聚氨基聚合物的方法,其包括以下步骤:(a)在反应条件下使多官能胺与不饱和烷基化剂接触以形成胺/不饱和烷基化剂加合物; (b)使加合物与多官能化合物接触,形成多聚氨基聚合物; (c)使多聚氨基聚合物与卤素,次卤酸或其前体接触,形成具有卤代醇或二卤官能团的聚氨基聚合物; 和(d)提高具有卤代醇或邻位二卤官能团的多聚氨基聚合物的pH足以引起分子量的增加。 或者,本发明是具有步骤(a),(b),(c)和任选(d)的方法,但是步骤(b)和(c)之间的步骤(h)使多胺聚合物与交联剂 因此具有至少两个与胺基反应的官能团,使得形成交联的聚氨基聚合物。 本发明包括如此制备的聚氨基聚合物,使用这种聚合物制备的纸张,以及制备这种纸张的方法。 这样制备的纸优选具有改善的湿强度。 当干燥和再溶解时,聚氨基聚合物是有用的。 某些聚氨基聚合物具有式IV的结构:(-R'N-(CnH2nNR)m-CO-Q-CO-),其中R和R'独立地为H或不饱和有机基团; n是单位重复m次的胺的重复单元中的氮原子之间的碳原子数; Q为二羧酸多官能化合物的二价有机基团。 式IV化合物也可以通过形成聚酰胺然后在高pH下用过量烷基化剂烷基化来制备。