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31. 发明授权

US07654948B2 Automated insomnia treatment system 有权
标题翻译：自动失眠治疗系统
公开(公告)号：US07654948B2
公开(公告)日：2010-02-02
申请号：US10790885
申请日：2004-03-01
申请人： Richard Kaplan , Kenneth A. Loparo
发明人： Richard Kaplan , Kenneth A. Loparo
IPC分类号： A61M21/00
CPC分类号： A61M21/00 , A61B5/4809 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0072 , A61M2230/10 , A61M2230/18 , A61M2230/42 , A61M2230/60 , A61M2230/63 , A61M2230/65
摘要： Automated behavioral methods and systems for treating insomnia that use passive means for determining wake/sleep states.
摘要翻译：用于治疗失眠的自动行为方法和系统，其使用被动方式来确定唤醒/睡眠状态。

32. 发明申请

US20080257349A1 Multilevel Ventilator 审中-公开
标题翻译：多层通风机
公开(公告)号：US20080257349A1
公开(公告)日：2008-10-23
申请号：US11568920
申请日：2005-05-10
申请人： Jan Hedner , Petter Knagenhjelm , Mikael Tiedje , Lutger Grote
发明人： Jan Hedner , Petter Knagenhjelm , Mikael Tiedje , Lutger Grote
IPC分类号： A61M16/00 , G05B13/02
CPC分类号： A61B5/02055 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/0496 , A61B5/083 , A61B5/087 , A61B5/4818 , A61B5/7264 , A61M16/026 , A61M2205/3375 , A61M2205/3553 , A61M2205/3584 , A61M2205/52 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/30 , A61M2230/432 , A61M2230/435 , G06F19/3418 , G06F19/3481 , G16H40/63 , G16H50/20 , Y02A90/24 , Y02A90/26
摘要： A method and apparatus for detecting breathing disorders and controlling a breathing ventilator using an artificial neural network working on signals indicative of a patient's physiological status. Preferably the artificial neural network works on a signal indicative of the pressure or flow of supplied breathing gas divided into two or more intervals (401, 402, 403, 404) indicative of patient (1) breathing cycle phases.
摘要翻译：一种用于检测呼吸障碍并且使用工作在指示患者的生理状态的信号的人造神经网络来控制呼吸呼吸机的方法和装置。优选地，人造神经网络工作在指示被分成指示患者（1）呼吸循环阶段的两个或更多个间隔（401,402,403,404）的供应呼吸气体的压力或流量的信号。

33. 发明申请

US20060258930A1 Device for use in sleep stage determination using frontal electrodes 审中-公开
标题翻译：用于使用正面电极进行睡眠阶段测定的装置
公开(公告)号：US20060258930A1
公开(公告)日：2006-11-16
申请号：US11435938
申请日：2006-05-18
申请人： Jianping Wu , Ronald Kurtz
发明人： Jianping Wu , Ronald Kurtz
IPC分类号： A61B5/04
CPC分类号： A61B5/0478 , A61B5/0002 , A61B5/0205 , A61B5/0492 , A61B5/0496 , A61B5/085 , A61B5/087 , A61B5/103 , A61B5/14552 , A61B5/4806 , A61B5/4812 , A61B5/4815 , A61B5/4818 , A61B5/6803 , A61B5/6814 , A61M16/06 , A61M16/0633 , A61M16/0683 , A61M2016/0021 , A61M2016/0027 , A61M2016/0036 , A61M2205/3553 , A61M2205/3561 , A61M2205/3592 , A61M2205/52 , A61M2205/8206 , A61M2230/04 , A61M2230/08 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/435 , A61M2230/62 , A61M2230/63
摘要： Embodiments relate to devices for use in sleep stage determination using frontal electrodes. One particular embodiment relates to a device for detecting electrical potentials corresponding to biological signals. The device comprises a flexible member for positioning over a forehead area of a human head and first, second and third electrodes located on the flexible member. The first electrode is located in a projecting portion of the flexible member to be positioned adjacent a nasion area of the head. The second electrode is to be positioned over a first lateral forehead area. The third electrode is to be positioned over a second lateral forehead area opposite the first lateral forehead area.
摘要翻译：实施例涉及用于使用正面电极进行睡眠阶段确定的装置。一个具体实施例涉及用于检测对应于生物信号的电位的装置。该装置包括用于定位在人头部的前额区域上的柔性构件以及位于柔性构件上的第一，第二和第三电极。第一电极位于柔性构件的突出部分中，以邻近头部的凹陷区域定位。第二电极被定位在第一横向前额区域上。第三电极被定位在与第一侧向额头区域相对的第二横向前额区域上。

34. 发明申请

US20060106275A1 Sleep guidance system and related methods 有权
标题翻译：睡眠指导系统及相关方法
公开(公告)号：US20060106275A1
公开(公告)日：2006-05-18
申请号：US11320058
申请日：2005-12-28
申请人： Keith Raniere
发明人： Keith Raniere
IPC分类号： A61M21/00
CPC分类号： A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2205/3569 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/20 , A61M2230/40 , A61M2230/50 , A61M2230/63 , Y10S128/905
摘要： A sleep efficiency monitor and methods for pacing and leading a sleeper through an optimal sleep pattern. Embodiments of the present invention include a physiological characteristic monitor for monitoring the sleep stages of a sleeper, a sensory stimulus generator for generating stimulus to affect the sleep stages of a sleeper, and a processor for determining what sleep stage the sleeper is in and what sensory stimulus is needed to cause the sleeper to move to another sleep stage. A personalized sleep profile may also be established for the sleeper and sleep guided in accordance with the profile parameters to optimize a sleep session. By providing sensory stimulus to a sleeper, the sleeper may be guided through the various sleep stages in an optimal pattern so that the sleeper awakens refreshed even if sleep is disrupted during the night or the sleeper's allotted sleep period is different than usual. Embodiments of the invention also involve calibration of the sleep guidance system to a particular sleeper.
摘要翻译：一种睡眠效率监测器和用于起搏和引导睡眠者通过最佳睡眠模式的方法。本发明的实施例包括用于监测睡眠者的睡眠阶段的生理特征监视器，用于产生刺激以影响睡眠者的睡眠阶段的感觉刺激发生器，以及用于确定卧铺睡眠阶段以及什么感觉的处理器刺激需要使睡眠者移动到另一个睡眠阶段。还可以根据轮廓参数为睡眠者和睡眠引导个人化睡眠概况，以优化睡眠会话。通过向睡眠者提供感觉刺激，睡眠者可以以最佳模式被引导穿过各种睡眠阶段，使得即使睡眠在夜晚中断睡眠或睡眠者的分配的睡眠期间不同于平常睡眠睡眠者也可以更新。本发明的实施例还涉及将睡眠引导系统校准到特定的睡眠者。

35. 发明申请

US20060102179A1 System and method for diagnosis and treatment of a breathing pattern of a patient 失效
公开(公告)号：US20060102179A1
公开(公告)日：2006-05-18
申请号：US11240197
申请日：2005-09-30
申请人： David Rapoport , Robert Norman
发明人： David Rapoport , Robert Norman
IPC分类号： A61M16/00
CPC分类号： A61M16/0069 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/0816 , A61B5/0826 , A61B5/087 , A61B5/4809 , A61B5/4812 , A61B5/4818 , A61B5/4836 , A61B5/7267 , A61B5/7282 , A61M16/00 , A61M16/0003 , A61M16/0066 , A61M16/026 , A61M16/06 , A61M2016/0021 , A61M2016/0027 , A61M2016/003 , A61M2016/0033 , A61M2016/0039 , A61M2016/0042 , A61M2205/3334 , A61M2205/3344 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/30 , A61M2230/42 , G06F19/00 , Y10S128/925
摘要： Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of a REM sleep state. In another embodiment, the processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of one of the following states: (i) a wake state and (ii) a sleep state. In another embodiment, a neural network analyzes the data to determine whether the breathing patterns are indicative of one of the following states: (i) a REM sleep state, (ii) a wake state and (iii) a sleep state. In another embodiment, the processing arrangement analyzes the data to determine whether the breathing pattern is indicative of an arousal.

36. 发明授权

US07041049B1 Sleep guidance system and related methods 有权
公开(公告)号：US07041049B1
公开(公告)日：2006-05-09
申请号：US10718960
申请日：2003-11-21
申请人： Keith Raniere
发明人： Keith Raniere
IPC分类号： A61M21/00
CPC分类号： A61M21/02 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0072 , A61M2205/3569 , A61M2205/3592 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/20 , A61M2230/40 , A61M2230/50 , A61M2230/63 , Y10S128/905
摘要： A sleep efficiency monitor and methods for pacing and leading a sleeper through an optimal sleep pattern. Embodiments of the present invention include a physiological characteristic monitor for monitoring the sleep stages of a sleeper, a sensory stimulus generator for generating stimulus to affect the sleep stages of a sleeper, and a processor for determining what sleep stage the sleeper is in and what sensory stimulus is needed to cause the sleeper to move to another sleep stage. A personalized sleep profile may also be established for the sleeper and sleep guided in accordance with the profile parameters to optimize a sleep session. By providing sensory stimulus to a sleeper, the sleeper may be guided through the various sleep stages in an optimal pattern so that the sleeper awakens refreshed even if sleep is disrupted during the night or the sleeper's allotted sleep period is different than usual. Embodiments of the invention also involve calibration of the sleep guidance system to a particular sleeper.

37. 发明申请

US20050283089A1 Method and apparatus useful in the diagnosis of obstructive sleep apnea of a patient 失效
标题翻译：用于诊断患者阻塞性睡眠呼吸暂停的方法和装置
公开(公告)号：US20050283089A1
公开(公告)日：2005-12-22
申请号：US11186695
申请日：2005-07-21
申请人： Colin Sullivan , Christopher Lynch
发明人： Colin Sullivan , Christopher Lynch
IPC分类号： A61B5/097 , A61B7/00 , A61F5/56 , A61M16/00 , A61M16/06 , A62B7/00
CPC分类号： A61B5/097 , A61B5/6814 , A61B7/003 , A61F5/56 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0024 , A61M2016/0036 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/432 , A61M2230/60
摘要： Patients may operate a CPAP system to deliver appropriate airway pressure at their home. A patient's apnea problem can be diagnosed at home without supervision with a CPAP device which delivers a continuously minimum appropriate pressure for substantially the entire period of therapy.
摘要翻译：患者可以运用CPAP系统在家中提供适当的气道压力。患者的呼吸暂停问题可以在家中进行诊断，而不用CPAP设备进行监督，CPAP设备在大体上整个治疗期间都能持续提供适当的压力。

38. 发明申请

US20050283039A1 System and method for manipulating sleep architecture by sub-awakening non-intrusive stimulations 有权
标题翻译：通过辅助唤醒非侵入性刺激来操纵睡眠结构的系统和方法
公开(公告)号：US20050283039A1
公开(公告)日：2005-12-22
申请号：US11210835
申请日：2005-08-25
申请人： Lustig Cornel
发明人： Lustig Cornel
IPC分类号： A61B20060101 , A61M21/00 , A61M21/02
CPC分类号： A61M21/02 , A61B2560/0242 , A61M21/00 , A61M2021/0016 , A61M2021/0022 , A61M2021/0027 , A61M2021/0044 , A61M2021/0055 , A61M2021/0066 , A61M2021/0083 , A61M2230/10 , A61M2230/18 , A61M2230/60
摘要： The present invention which is a new system and method employing stimulation control to treat sleep disorders, and improve sleep states operates in a dynamic, adaptable manner without causing a premature state of arousal. Stimulation is achieved by controlling a wide variety of environmental factors around the sleeping person. The invention is based on a real-time, self-adaptive feedback system including a sleep and environment monitoring unit or a preset adjustable protocol, an integrating, controlling and deciding unit and a stimulation unit. The system and method take into account individual variability and sensitivity to sensory stimulation and phenomena as adaptation and sensitization. The system and method are aimed at improving the overall sleep architecture, and correcting specific disorders. Alternatively the same invention may be used to promote alertness, specific moods and conditions in the awake subject. The invention may be used by professional in sleep laboratories or by individuals in a home environment. It may be adjusted to operate on groups of people and on non-human subjects.
摘要翻译：作为使用刺激控制来治疗睡眠障碍并改善睡眠状态的新系统和方法的本发明以动态的，适应性的方式运作，而不引起过早的觉醒状态。刺激是通过控制睡眠者周围的各种环境因素来实现的。本发明基于包括睡眠和环境监测单元或预设可调协议，集成，控制和决定单元和刺激单元的实时自适应反馈系统。系统和方法考虑到感觉刺激和现象的个体变异性和敏感性作为适应和敏化。该系统和方法旨在改善整体睡眠结构，并纠正特定疾病。或者，可以使用相同的发明来促进清醒对象中的警觉性，特定情绪和状况。本发明可以由专业人员在睡眠实验室或家庭环境中的个人使用。它可以调整为对一群人和非人类受试者进行操作。

39. 发明授权

US06705315B2 Device for monitoring breathing during sleep and ramped control of CPAP treatment 失效
标题翻译：在睡眠期间监测呼吸和CPAP治疗的控制的装置
公开(公告)号：US06705315B2
公开(公告)日：2004-03-16
申请号：US09875326
申请日：2001-06-06
申请人： Colin E. Sullivan , Christopher Lynch
发明人： Colin E. Sullivan , Christopher Lynch
IPC分类号： A61M1600
CPC分类号： A61B5/097 , A61B5/6814 , A61B7/003 , A61F5/56 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0024 , A61M2016/0036 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/432 , A61M2230/60
摘要： A CPAP apparatus including: a variable pressured air source and means to vary the air pressure delivered therefrom; a nose piece for sealed air communication with a patient's respiratory system; an air communication line from the air source to the nose piece; a sound transducer adapted to be in sound communication with the patient's respiratory system; and a feedback system controlling the output pressure of the air source in response to an output from the transducer so as to increase the output air pressure from said air source, in response to detection of sound indicative of snoring, in accordance with a predefined procedure. The sound transducer, in its most general form, comprises a pressure transducer which, in addition to detecting snoring sounds, can detect other respiratory parameters such as the rate of breathing, inhaled air flow volume, and inhaled air flow rate. Output air pressure from air source is increased in response to one or more of these parameters in accordance with a pre-defined procedure.
摘要翻译：一种CPAP设备，包括：可变压力空气源和改变从其传送的空气压力的装置; 用于与患者的呼吸系统进行密封空气通信的鼻片; 从空气源到鼻片的空气通信线; 适于与患者呼吸系统进行声音通信的声音换能器; 以及反馈系统，其响应于来自换能器的输出来控制空气源的输出压力，以响应于根据预定义的过程检测到指示打鼾的声音来增加来自所述空气源的输出空气压力。声音传感器在其最通用的形式中包括一个压力传感器，除了检测打鼾的声音之外，还可以检测其他呼吸参数，例如呼吸速率，吸入空气流量和吸入空气流速。响应于根据预定义过程的这些参数中的一个或多个，来自空气源的输出空气压力增加。

40. 发明申请

US20020100477A1 Method and apparatus useful in the diagnosis of obstructive sleep apnea of a patient 失效
公开(公告)号：US20020100477A1
公开(公告)日：2002-08-01
申请号：US10086444
申请日：2002-03-04
申请人： ResMed Limited
发明人： Colin Edward Sullivan , Christopher Lynch
IPC分类号： A62B007/00 , A61M016/00 , F16K031/02 , A61B005/08
CPC分类号： A61B5/097 , A61B5/6814 , A61B7/003 , A61F5/56 , A61M16/0051 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0024 , A61M2016/0036 , A61M2230/04 , A61M2230/10 , A61M2230/18 , A61M2230/205 , A61M2230/432 , A61M2230/60
摘要： Patients may operate a CPAP system to deliver appropriate airway pressure at their home. A patient's apnea problem ca be diagnosed at home without supervision with a CPAP device which delivers a continuously minimum appropriate pressure for substantially the entire period of therapy.

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