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31. 发明申请

US20070167725A1 Systems, methods and apparatus for an endo-rectal receive-only probe 有权
标题翻译：用于直肠内接受探针的系统，方法和装置
公开(公告)号：US20070167725A1
公开(公告)日：2007-07-19
申请号：US11320361
申请日：2005-12-27
申请人： James Tropp , Paul Calderon , Daniel Vigneron , Konstantinos Karpodinis , Lucas Carvajal
发明人： James Tropp , Paul Calderon , Daniel Vigneron , Konstantinos Karpodinis , Lucas Carvajal
IPC分类号： A61B5/05
CPC分类号： G01R33/3657 , A61B1/31 , A61B5/055 , A61B5/4381 , A61B5/68 , A61B2562/02 , G01R33/287 , G01R33/3635
摘要： Systems, methods and apparatus are provided through which a compact pod insertable into the rectum for Magnetic Resonance Imaging/Magnetic Resonance Spectroscopy (MRI/MRS) examination of the prostate and containing two receive coils, each connected to transmit blocking and pre-tuned trap circuitry which can be superimposed within the pod in close proximity, can, without either circuit interfering with the other, efficiently gather, for imaging and tissue analysis, radio frequency signals emanating from magnetically disturbed nuclei in prostate tissue.
摘要翻译：提供了一种系统，方法和装置，通过该系统，方法和装置将可插入直肠的紧凑型盒体用于前列腺的磁共振成像/磁共振光谱（MRI / MRS）检查，并包含两个接收线圈，每个接收线圈连接到传输阻塞和预调谐陷波电路可以在舱内叠加在靠近的位置，可以在没有电路干扰另一个的情况下，有效地收集来自前列腺组织中的磁性干扰的核发出的射频信号，用于成像和组织分析。

32. 发明申请

US20040254445A1 Use of MRI to screen individuals for prostate cancer 审中-公开
标题翻译：使用MRI筛查个人前列腺癌
公开(公告)号：US20040254445A1
公开(公告)日：2004-12-16
申请号：US10460798
申请日：2003-06-13
发明人： Craig Bittner
IPC分类号： A61B005/05
CPC分类号： A61B5/4381 , A61B5/055
摘要： Methods of screening individuals for prostate cancer are provided, which may enable early diagnosis of prostate cancer. The methods may involve the use of a contrast agent while screening individuals using MRI technology. The methods may involve the use of MRI spectroscopy while screening individuals using MRI technology. Also provided are methods of detecting prostate cancer in individuals, which include screening such individuals using MRI technology.
摘要翻译：提供筛选前列腺癌个体的方法，其可以使得能够早期诊断前列腺癌。该方法可以涉及使用造影剂，同时使用MRI技术筛选个体。该方法可能涉及使用MRI光谱，同时使用MRI技术筛选个体。还提供了检测个体中前列腺癌的方法，其包括使用MRI技术筛选这些个体。

33. 发明授权

US06685702B2 Device for treating tissue and methods thereof 失效
标题翻译：用于治疗组织的装置及其方法
公开(公告)号：US06685702B2
公开(公告)日：2004-02-03
申请号：US09900586
申请日：2001-07-06
申请人： Rodolfo C. Quijano , Hosheng Tu
发明人： Rodolfo C. Quijano , Hosheng Tu
IPC分类号： A61B1814
CPC分类号： A61B5/053 , A61B5/0538 , A61B5/4381
摘要： A method and devices for treating a target tissue comprising providing thermal energy to the target tissue and simultaneously providing cryogenic energy to peripheral tissue adjacent or surrounding said target tissue adapted for shielding the peripheral tissue from any adverse effect of the thermal energy. The cooling may be accomplished with a cryogenic arrangement comprising two elements of different electromotive potential conductively connected at a probe junction, and passing an electrical current through the elements to reduce a temperature of the probe junction in accordance with the Peltier effect.
摘要翻译：一种用于治疗靶组织的方法和装置，包括向靶组织提供热能，并且同时向毗邻或围绕所述靶组织的周围组织提供低温能量，适用于屏蔽周边组织免受热能的任何不利影响。冷却可以通过低温装置来实现，该低温装置包括在探针结处导电连接的不同电动势的两个元件，并且使电流通过元件以根据珀耳帖效应降低探针结的温度。

34. 发明申请

US20040010192A1 Optical imaging of induced signals in vivo under ambient light conditions 有权
标题翻译：诱导信号在环境光条件下的体内光学成像
公开(公告)号：US20040010192A1
公开(公告)日：2004-01-15
申请号：US10437670
申请日：2003-05-13
申请人： Spectros Corporation
发明人： David A. Benaron , Yair Talmi , Ilian H. Parachikov
IPC分类号： A61B006/00
CPC分类号： B82Y20/00 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/415 , A61B5/418 , A61B5/4381 , A61B5/7285 , A61B2503/40 , B82Y5/00 , B82Y10/00
摘要： A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals from the detector, and passes these signals to memory for accumulation and storage, and to then to image processing engine for determination of the localization and distribution of the contrast agent. The computer also provides an output signal based upon the localization and distribution of the contrast agent, allowing trace amounts of the target tissue to be detected, located, or imaged. A system for carrying out the method is also described.
摘要翻译：一种用于在存在环境光的情况下检测和定位身体内的目标组织的方法，其中光学造影剂被施用并被允许其功能地定位在待诊断的造影剂标记的靶组织内。光源光学耦合到潜在地包含对比度标记的靶组织的组织区域。门控光检测器光学耦合到组织区域并被布置成检测与环境光相比基本上富集目标信号的光，其中目标信号是已经通过对比度标记的组织区域并被对比剂修饰的光。计算机从检测器接收信号，并将这些信号传递到存储器用于累积和存储，然后传送到图像处理引擎以确定造影剂的定位和分布。计算机还基于造影剂的定位和分布提供输出信号，允许检测，定位或成像痕量的靶组织。还描述了用于执行该方法的系统。

35. 发明授权

US06549800B1 Methods for in vivo magnetic resonance imaging 有权
标题翻译：体内磁共振成像方法
公开(公告)号：US06549800B1
公开(公告)日：2003-04-15
申请号：US09549921
申请日：2000-04-14
申请人： Ergin Atalar , Paul A. Bottomley , Elias Zerhouin , Henry Halperin , Elliot McVeigh , Albert C. Lardo
发明人： Ergin Atalar , Paul A. Bottomley , Elias Zerhouin , Henry Halperin , Elliot McVeigh , Albert C. Lardo
IPC分类号： A61B505
CPC分类号： A61B5/415 , A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , A61B5/418 , A61B5/42 , A61B5/4381 , A61B10/0275 , A61B2090/374 , G01R33/285 , G01R33/34084 , G01R33/3628 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/44 , H01Q11/08
摘要： The systems and methods of the present invention provide for MRI probes adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof and to treat the diagnosed abnormalities. MRI probes are described that are suitable for use in the mediastinum, in the pancreaticohepaticobiliary system, in the tracheobronchopulmonary system, in the head and neck, in the genitourinary system, the gastrointestinal system, the vascular system, and in the evaluation, diagnosis and treatment of internal fluid collections.
摘要翻译：本发明的系统和方法提供适于插入多个体孔的MRI探针，以评估近端解剖结构的解剖结构，诊断其异常并治疗诊断异常。描述了适用于纵隔，胰胆管系统，气管支气管系统，头颈部，泌尿生殖系统，胃肠系统，血管系统以及评估，诊断和治疗中的MRI探针的内部流体收集。

36. 发明申请

US20020040185A1 Systems and methods for evaluating the urethra and the periurethral tissues 有权
标题翻译：用于评估尿道和尿道周围组织的系统和方法
公开(公告)号：US20020040185A1
公开(公告)日：2002-04-04
申请号：US09824536
申请日：2001-04-02
发明人： Ergin Atalar , Harald Quick , Parag Karmarkar
IPC分类号： A61B005/055
CPC分类号： G01R33/34084 , A61B1/273 , A61B1/303 , A61B1/307 , A61B1/31 , A61B5/055 , A61B5/415 , A61B5/418 , A61B5/4381 , G01R33/285 , G01R33/34007 , G01R33/341 , H01Q1/36 , H01Q1/362 , H01Q1/40 , H01Q1/44 , H01Q11/08
摘要： The present invention provides systems and methods for the evaluation of the urethra and periurethral tissues using an MRI coil adapted for insertion into the male, female or pediatric urethra. The MRI coil may be in electrical communication with an interface circuit made up of a tuning-matching circuit, a decoupling circuit and a balun circuit. The interface circuit may also be in electrical communication with a MRI machine. In certain practices, the present invention provides methods for the diagnosis and treatment of conditions involving the urethra and periurethral tissues, including disorders of the female pelvic floor, conditions of the prostate and anomalies of the pediatric pelvis.
摘要翻译：本发明提供了使用适于插入到男性，女性或儿科尿道中的MRI线圈来评估尿道和尿道周围组织的系统和方法。 MRI线圈可以与由调谐匹配电路，去耦电路和平衡 - 不平衡转换电路组成的接口电路电连通。接口电路也可以与MRI机器电连通。在某些实践中，本发明提供了用于诊断和治疗涉及尿道和尿道周围组织的病症的方法，包括女性骨盆底部疾病，前列腺疾病和儿科骨盆异常。

37. 发明授权

US6004267A Method for diagnosing and staging prostate cancer 失效
标题翻译：诊断和分期前列腺癌的方法
公开(公告)号：US6004267A
公开(公告)日：1999-12-21
申请号：US36307
申请日：1998-03-06
申请人： Ashutosh Tewari , Perinchery Narayan
发明人： Ashutosh Tewari , Perinchery Narayan
IPC分类号： A61B5/06 , G06F19/00 , A01B5/00
CPC分类号： A61B5/06 , A61B5/415 , A61B5/418 , A61B5/4381 , A61B5/7267 , G06F19/345 , Y10S128/925
摘要： The subject invention provides a method for diagnosing prostate cancer and determining preoperatively the pathological stage in patients with prostate cancer. The methods described herein can be used for prediction of margin positivity, seminal vesicle (S.V.) involvement, and lymph nodal (L.N.) involvement in patients with clinically localized prostate cancer. The method includes use of a neural network which provides prostate cancer stage information for a patient based upon input data which includes the patient's preoperative serum PSA, biopsy Gleason score, and systemic biopsy-based information. Its positive predictive value (PPV), negative predictive value (NPV), and accuracy are superior to that of current nomograms in use. Use of this method can result in enormous cost savings by accurately diagnosing patients with prostate cancer and by avoiding multiple imaging tests and expensive surgery in unindicated patients.
摘要翻译：本发明提供了一种用于诊断前列腺癌并在术前确定前列腺癌患者的病理分期的方法。本文描述的方法可用于预测边缘阳性，精囊（S.V.）参与和淋巴结（L.N.）参与临床局限性前列腺癌患者。该方法包括使用神经网络，其基于包括患者术前血清PSA，活检Gleason评分和全身活组织检查的信息的输入数据为患者提供前列腺癌阶段信息。其阳性预测值（PPV），阴性预测值（NPV）和准确度优于目前使用的图表。使用这种方法可以通过准确诊断患有前列腺癌的患者，并通过避免多次成像测试和昂贵的手术在无指征的患者中实现巨大的成本节省。

38. 发明授权

US5949845A Temperature-measuring microwave radiometer apparatus 失效
标题翻译：温度测量微波辐射仪
公开(公告)号：US5949845A
公开(公告)日：1999-09-07
申请号：US896450
申请日：1997-07-18
申请人： Fred Sterzer
发明人： Fred Sterzer
IPC分类号： A61B5/00 , G01K11/00 , A61B6/04
CPC分类号： A61B5/0507 , A61B5/015 , A61B5/4381 , G01K11/006
摘要： Disclosed are four improvements in temperature-measuring radiometric equipment. The first improvement is directed to increasing the sensitivity of a radiometer by employing microwave noise power derived from a reference noise source in an amount that corresponds to a temperature higher than that of the specimen, and applying the reference-noise-source-derived microwave noise power as an input to the radiometer for a shorter time than is microwave noise power derived from a specimen. The second improvement is directed to reducing emissivity error by employing open-loop means comprising a microwave circulator for applying microwave noise power generated by at least one resistor thermostatically heated to a temperature in the neighborhood of the temperature of a patient's body tissue back to the body tissue. The third improvement, which is suitable for use in an applicator insertable into a natural opening of a patient's body that is employed in the detection and location of a cancerous lesion, is directed to a microwave radiometer that employs two displaced microwave antennas to measure the temperature difference between two points of a patient's body tissue or other type of specimen. The fourth improvement is directed to radiometric equipment that is combined with mammographic equipment to provide a superior capability for detecting and locating a breast cancer lesion.
摘要翻译：披露了温度测量辐射测量设备的四项改进。第一个改进是针对通过使用从参考噪声源导出的微波噪声功率来提高辐射计的灵敏度，其量对应于比样本的温度高的温度，以及将参考噪声源衍生的微波噪声作为辐射计的输入的时间短于来自样本的微波噪声功率。第二个改进是针对通过采用开环装置来降低发射率误差，所述开环装置包括微波循环器，用于将由至少一个恒温加热到患者身体组织的温度附近的温度的至少一个电阻产生的微波噪声功率提供给身体组织。适用于可插入到用于检测和定位癌性病变的患者身体的天然开口中的施放器的第三改进被引导到微波辐射计，其使用两个置换的微波天线来测量温度患者的身体组织或其他类型的标本的两点之间的差异。第四个改进是针对与乳房X线照相设备相结合的辐射测量设备，以提供检测和定位乳腺癌病变的优越能力。

39. 发明授权

US5331548A Method and system for on-line measurement, storage, retrieval and analysis of urodynamical data 失效
标题翻译：在线测量，存储，检索和分析尿动力学数据的方法和系统
公开(公告)号：US5331548A
公开(公告)日：1994-07-19
申请号：US783045
申请日：1991-10-28
申请人： Harm J. Rollema , Ron van Mastrigt
发明人： Harm J. Rollema , Ron van Mastrigt
IPC分类号： A61B5/20 , A61B17/00 , G06F19/00 , A61B10/00
CPC分类号： A61B5/4381 , A61B5/205 , A61B5/208 , G06F19/3487 , A61B2017/00274 , A61B2018/00547 , G06F19/322 , G06F19/3406
摘要： A computerized urological diagnostic method and system for use, for example, in preoperative assessment of prostatectomy candidates and other therapeutical measures in patients (males and females) with voiding complaints. The system includes a digital processor, a database, suitable input/output devices, and pressure and flow rate trandsucers for measure the patient's isometric detrusor pressure immediately before voiding and detrusor pressure and flow rate during micturition. These signals are processed and displayed to provide the clinician with objective data of bladder contractility and urethral resistance. With such data, the clinician can make informed treatment decisions.
摘要翻译：一种计算机化的泌尿系统诊断方法和系统，例如在术前评估前列腺切除术候选人和其他治疗措施（男性和女性）中进行排尿投诉。该系统包括数字处理器，数据库，合适的输入/输出装置，以及用于在排尿之前立即测量患者的等距逼尿肌压力以及排尿期间的逼尿肌压力和流量的压力和流量分级器。这些信号被处理和显示，以向临床医生提供膀胱收缩性和尿道阻力的客观数据。有了这样的数据，临床医生可以做出明智的治疗决定。

40. 发明申请

US20190183462A1 ECHO WINDOW ARTIFACT CLASSIFICATION AND VISUAL INDICATORS FOR AN ULTRASOUND SYSTEM 审中-公开
公开(公告)号：US20190183462A1
公开(公告)日：2019-06-20
申请号：US16213418
申请日：2018-12-07
申请人： Verathon Inc.
发明人： Fuxing Yang , Joon Hwan Choi
IPC分类号： A61B8/08 , A61B8/14 , A61B8/00 , G06N3/08 , G06N3/04 , G06K9/62 , G06T7/00
CPC分类号： A61B8/5223 , A61B5/4325 , A61B5/4381 , A61B5/7267 , A61B8/085 , A61B8/145 , A61B8/463 , A61B8/5269 , A61B8/5292 , G06K9/627 , G06K9/628 , G06N3/04 , G06N3/0454 , G06N3/08 , G06T5/001 , G06T7/0012 , G06T2207/10132 , G06T2207/20081 , G06T2207/20084 , G06T2207/30168 , G16H30/40 , G16H50/20
摘要： A method for providing artifact detection and visualization during ultrasound image collection is performed by a processor in an ultrasound system. The method includes receiving ultrasound image data from an ultrasound probe, detecting areas with artifacts in the ultrasound image data, classifying the areas with artifacts into one of a plurality of available artifact classes, generating an indication of the areas with artifact for an ultrasound-based image, wherein the indications include a designation of the artifact class, and presenting to an operator the ultrasound-based image and the indication of the areas with artifacts.

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