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31. 发明申请

US20130237853A1 Geometry of a Transcutaneous Sensor 审中-公开
标题翻译：经皮传感器几何
公开(公告)号：US20130237853A1
公开(公告)日：2013-09-12
申请号：US13792066
申请日：2013-03-09
申请人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema , IVWATCH, LLC
发明人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema
IPC分类号： A61B5/00
CPC分类号： B23P19/04 , A61B5/0082 , A61B5/0507 , A61B5/443 , A61B2562/0242 , A61B2562/12 , A61M5/16836 , B23P25/00 , Y10T29/49764 , Y10T29/49826 , Y10T29/53052 , Y10T29/49771 , Y10T29/49888 , Y10T29/49885 , Y10T29/4989
摘要： A housing for a transcutaneous electromagnetic signal sensor including an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue.
摘要翻译：一种用于经皮电磁信号传感器的壳体，包括发射器和收集器。发射器包括被配置为发射进入动物界组织的第一电磁辐射信号的发射器端面。收集器包括被配置为收集离开动物界组织的第二电磁辐射信号的检测器端面。第二电磁辐射信号包括第一电磁辐射信号的一部分，其是从动物组织反射，散射和重定向中的至少一个。第二电磁辐射信号监测动物组织中随时间的解剖变化。

32. 发明申请

US20130237851A1 Geometry of a Transcutaneous Sensor 审中-公开
公开(公告)号：US20130237851A1
公开(公告)日：2013-09-12
申请号：US13792061
申请日：2013-03-09
申请人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema , IVWATCH, LLC
发明人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema
IPC分类号： A61B5/00
CPC分类号： B23P19/04 , A61B5/0082 , A61B5/0507 , A61B5/443 , A61B2562/0242 , A61B2562/12 , A61M5/16836 , B23P25/00 , Y10T29/49764 , Y10T29/49826 , Y10T29/53052 , Y10T29/49771 , Y10T29/49888 , Y10T29/49885 , Y10T29/4989
摘要： A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue.

33. 发明申请

US20130237849A1 Geometry of a Transcutaneous Sensor 审中-公开
公开(公告)号：US20130237849A1
公开(公告)日：2013-09-12
申请号：US13792053
申请日：2013-03-09
申请人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema , IVWATCH, LLC
发明人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema
IPC分类号： A61B5/00
CPC分类号： B23P19/04 , A61B5/0082 , A61B5/0507 , A61B5/443 , A61B2562/0242 , A61B2562/12 , A61M5/16836 , B23P25/00 , Y10T29/49764 , Y10T29/49826 , Y10T29/53052 , Y10T29/49771 , Y10T29/49888 , Y10T29/49885 , Y10T29/4989
摘要： A transcutaneous electromagnetic signal sensor includes an emitter and a collector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue.

34. 发明申请

US20130232760A1 Method of Manufacturing a Transcutaneous Sensor 审中-公开
公开(公告)号：US20130232760A1
公开(公告)日：2013-09-12
申请号：US13792069
申请日：2013-03-10
申请人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema , IVWATCH, LLC
发明人： Gary P. Warren , Matthew S. Alley , Scott J. Anchell , William J. Naramore , Garret T. Bonnema
IPC分类号： B23P25/00
CPC分类号： B23P19/04 , A61B5/0082 , A61B5/0507 , A61B5/443 , A61B2562/0242 , A61B2562/12 , A61M5/16836 , B23P25/00 , Y10T29/49764 , Y10T29/49826 , Y10T29/53052 , Y10T29/49771 , Y10T29/49888 , Y10T29/49885 , Y10T29/4989
摘要： A method of manufacturing a transcutaneous electromagnetic signal sensor including an emitter and a detector. The emitter includes an emitter end face configured to emit a first electromagnetic radiation signal that enters Animalia tissue. The collector includes a detector end face configured to collect a second electromagnetic radiation signal that exits the Animalia tissue. The second electromagnetic radiation signal includes a portion of the first electromagnetic radiation signal that is at least one of reflected, scattered and redirected from the Animalia tissue. The second electromagnetic radiation signal monitors anatomical changes over time in the Animalia tissue.

35. 发明授权

US08521244B2 Physiological parameter monitoring apparatus 失效
标题翻译：生理参数监测仪
公开(公告)号：US08521244B2
公开(公告)日：2013-08-27
申请号：US12560744
申请日：2009-09-16
申请人： Lewis Norman Harrold
发明人： Lewis Norman Harrold
IPC分类号： A61B5/1455
CPC分类号： A61B5/14552 , A61B5/6833 , A61B2562/0242 , A61B2562/146 , A61B2562/164
摘要： A tissue oximeter sensor includes a substrate with a non-zero finite depth and first and second major sides. At least a first material free region extends along the depth from one of the sides to the other of the two sides forming a first well in the substrate. One of the sides of the substrate is configured to be removeably affixed to a human or animal subject. The sensor also includes a first channel with first and second end portions. One of the end portions of the first channel is selectively positioned in the first well along the depth alternatively at one of a plurality of different depth positions. The first channel routes radiation at least one of from the first end portion to the second end portion or from the second end portion to the first end portion.
摘要翻译：组织血氧计传感器包括具有非零有限深度和第一和第二主要侧面的基底。至少第一材料自由区域沿着从底板中的一个侧面到另一个侧面的深度延伸，形成衬底中的第一阱。衬底的一个侧面被配置为可移除地固定到人或动物受试者。传感器还包括具有第一和第二端部的第一通道。第一通道的一个端部选择性地沿着深度沿着深度位于多个不同深度位置中的一个处。第一通道将从第一端部到第二端部中的至少一个或从第二端部至第一端部中的至少一个辐射。

36. 发明申请

US20130100449A1 METHOD AND DEVICE FOR MEASURING SCATTERING-ABSORPTION BODY 有权
标题翻译：用于测量散射吸收体的方法和装置
公开(公告)号：US20130100449A1
公开(公告)日：2013-04-25
申请号：US13695362
申请日：2011-03-29
申请人： Etsuko Yamaki , Yutaka Yamashita , Motoki Oda , Hiroaki Suzuki , Toshihiko Suzuki , Hiroshi Watanabe , Shunsaku Koga
发明人： Etsuko Yamaki , Yutaka Yamashita , Motoki Oda , Hiroaki Suzuki , Toshihiko Suzuki , Hiroshi Watanabe , Shunsaku Koga
IPC分类号： G01N21/17
CPC分类号： G01N21/17 , A61B5/14546 , A61B5/1455 , A61B2562/0242 , G01N21/359 , G01N21/49
摘要： Light irradiates one light incident position on the surface of a scattering-absorption body. The light that propagates through the interior of the scattering-absorption body is detected at one light detecting position on the surface of the scattering-absorption body. On the basis of a light detection signal, a temporal profile of the light intensity of the detected light is acquired, and on the basis of the temporal profile, an mean optical path length of the light in the interior of the scattering-absorption body and information relating to the amount of substance to be measured in a region to be measured are calculated. The information relating to the amount of substance to be measured is corrected on the basis of the mean optical path length, such that the longer the mean optical path length, the greater the amount of substance to be measured is.
摘要翻译：光照射散射吸收体表面上的一个光入射位置。在散射吸收体的表面的一个光检测位置处检测通过散射吸收体的内部传播的光。基于光检测信号，获取检测光的光强度的时间分布，并且基于时间分布，散射吸收体内部的光的平均光路长度和计算与要测量的区域中的待测物质量有关的信息。基于平均光程长度校正与被测量物质量有关的信息，使得平均光程长度越长，待测物质量越多。

37. 发明申请

US20130018237A1 APPARATUS FOR NON-INVASIVE IN VIVO MEASUREMENT BY RAMAN SPECTROSCOPY 有权
标题翻译：通过拉曼光谱测量非侵入血糖的装置
公开(公告)号：US20130018237A1
公开(公告)日：2013-01-17
申请号：US13542462
申请日：2012-07-05
申请人： Morten HENNEBERG , Stefan Ovesen Banke , Anders Weber
发明人： Morten HENNEBERG , Stefan Ovesen Banke , Anders Weber
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/0068 , A61B5/0075 , A61B5/1451 , A61B5/14532 , A61B5/1495 , A61B5/441 , A61B2562/0238 , A61B2562/0242 , A61B2562/146 , G01N21/65
摘要： A metabolite concentration is measured in vivo using Raman spectroscopy in such a way as to receive at a detector (229) light scattered from the metabolite in interstitial fluid in skin in a measurement location (217) at a depth (218) of from 200-300 μm below the skin surface providing improved retention of correct calibration and transferability of calibration between individual subjects.
摘要翻译：在体内使用拉曼光谱测量代谢物浓度，以便在检测器（229）中从位于测量位置（217）处的间隔液（217）中的代谢物散射的光在深度（218）处接收来自200- 皮肤表面300μm以下，可提供保持正确的校准和个体受试者之间校准的可转移性。

38. 发明申请

US20120101347A1 CONCENTRATION DETERMINATION APPARATUS, CONCENTRATION DETERMINATION METHOD, AND PROGRAM 有权
标题翻译：浓度测定装置，浓度测定方法和程序
公开(公告)号：US20120101347A1
公开(公告)日：2012-04-26
申请号：US13274744
申请日：2011-10-17
申请人： Kazuhiko AMANO , Koichi SHIMIZU
发明人： Kazuhiko AMANO , Koichi SHIMIZU
IPC分类号： A61B5/1455
CPC分类号： A61B5/14532 , A61B5/1455 , A61B2562/0242
摘要： A concentration determination apparatus may include: an irradiation unit that irradiates short-pulsed light to an observed object; a light receiving unit that receives light backscattered from the observed object; a light intensity acquisition unit that acquires an intensity distribution of the light; an optical path length distribution storage unit that stores a model of an optical path length distribution in each layer of the plurality of layers of the short-pulsed light; an optical path length acquisition unit that acquires the optical path length distribution of each layer; a time-resolved waveform storage unit that stores a model of a time-resolved waveform; a light intensity model acquisition unit that acquires a light intensity model; an integral interval calculation unit that calculates a time range of an area; an optical absorption coefficient calculation and acquisition unit that calculates and acquires an optical absorption coefficient; and a concentration calculation unit that calculates the concentration.
摘要翻译：浓度测定装置可以包括：向观察对象照射短脉冲光的照射单元; 光接收单元，其接收从观察对象反射的光; 获取光的强度分布的光强度获取单元; 光路长度分布存储单元，其存储所述短脉冲光的所述多层的各层中的光路长度分布的模型; 获取各层的光路长度分布的光路长度取得部，时间分辨波形存储单元，其存储时间分辨波形的模型; 获取光强度模型的光强度模型获取单元; 积分间隔计算单元，计算区域的时间范围; 计算并获取光吸收系数的光吸收系数计算和获取单元; 以及计算浓度的浓度计算单元。

39. 发明申请

US20110205535A1 SPECTROSCOPIC SENSORS 有权
标题翻译：光谱传感器
公开(公告)号：US20110205535A1
公开(公告)日：2011-08-25
申请号：US13057617
申请日：2009-08-07
申请人： Babs R. Soller , John Coates , Ye Yang , Chunguang Jin
发明人： Babs R. Soller , John Coates , Ye Yang , Chunguang Jin
IPC分类号： G01J3/42
CPC分类号： A61B5/1455 , A61B5/0082 , A61B5/145 , A61B5/14539 , A61B5/14552 , A61B5/412 , A61B5/6801 , A61B2562/0233 , A61B2562/0238 , A61B2562/0242 , A61B2562/04 , A61B2562/046
摘要： Disclosed herein are sensors that include: (a) a circuit board that includes an electronic processor; (b) a plurality of radiation sources, each source being attached to the circuit board; and (c) a spectral detector attached to the circuit board, the spectral detector being configured to analyze radiation derived from one or more of the plurality of radiation sources. During use, the sensors are configured to be worn on a portion of a body of a subject. The electronic processor is configured to cause two or more of the plurality of radiation sources to direct incident radiation to the subject, to cause the spectral detector to analyze radiation from the subject, and to determine one or more properties of the subject based on the radiation from the subject. Methods of making and using these sensors are also disclosed.
摘要翻译：这里公开的传感器包括：（a）包括电子处理器的电路板; （b）多个辐射源，每个源连接到电路板; 和（c）附着到电路板的光谱检测器，所述光谱检测器被配置为分析从多个辐射源中的一个或多个发射的辐射。在使用期间，传感器被配置成佩戴在被检体的身体的一部分上。电子处理器被配置为使得多个辐射源中的两个或更多个辐射源将入射辐射引导到对象，以使得光谱检测器分析来自对象的辐射，并且基于辐射来确定对象的一个或多个属性从主题。还公开了制造和使用这些传感器的方法。

40. 发明授权

US07999938B2 Measurements of optical inhomogeneity and other properties in substances using propagation modes of light 有权
标题翻译：使用光的传播模式测量物质中的光学不均匀性和其他性质
公开(公告)号：US07999938B2
公开(公告)日：2011-08-16
申请号：US12569835
申请日：2009-09-29
申请人： Feiling Wang
发明人： Feiling Wang
IPC分类号： G01B9/02 , G01J4/00
CPC分类号： G01N21/55 , A61B5/0059 , A61B5/0066 , A61B5/0073 , A61B5/14532 , A61B5/1455 , A61B5/14558 , A61B2562/0242 , G01B9/0201 , G01B9/02044 , G01B9/02057 , G01B9/02091 , G01B2290/35 , G01B2290/40 , G01B2290/45 , G01B2290/70 , G01J3/02 , G01J3/021 , G01J3/0218 , G01J3/0224 , G01J3/42 , G01N21/21 , G01N21/27 , G01N21/474 , G01N21/4795 , G01N21/49 , G01N2021/4709 , G01N2021/4792 , G02B21/06
摘要： This application describes designs, implementations, and techniques for controlling propagation mode or modes of light in a common optical path, which may include one or more waveguides, to sense a sample.
摘要翻译：该应用描述了用于控制公共光路中的传播模式或光模式的设计，实现和技术，其可以包括一个或多个波导以感测样本。

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